Anti-Iba1 antibodies enable researchers to detect and measure the Iba1 antigen in biological samples. This target is a reported synonym of the AIF1 gene, which encodes allograft inflammatory factor 1. This protein is known to function in the response to oxidative stress, among other biological roles. The human version of Iba1 has a canonical amino acid length of 147 residues and a protein mass of 16.7 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the membrane and cytoplasm of cells and notably expressed in many tissues, such as the bone marrow and cerebellum. The Iba1 marker has been described in the characterization of Brain Microglia, Macrophages, and Microglia.*
*HuBMAP Human Reference Atlas v1.4