Anti-BCL2 antibodies are used in the immunodetection of the protein BCL2 apoptosis regulator. In humans, the canonical protein has a reported length of 239 amino acid residues and a mass of 26.3 kDa. Its subcellular localization is in the nucleus, mitochondria, ER, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in a variety of tissues. A member of the Bcl-2 protein family, BCL2 is known to be involved with the apoptotic pathway and neuronal development. Synonyms for this target antigen include apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, protein phosphatase 1, regulatory subunit 50, and PPP1R50. BCL2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 8900 citations in the literature describe the use of BCL2 antibodies in research. Western Blot is a widely used application for these antibodies. Flow Cytometry, Immunofluorescence, and Immunohistochemistry are also common applications.