Bcl-2 in Mouse T cells

Immunology
Northwestern University
Grad Student

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Company:

Cell Signaling Technology

Product Name:

Bcl-2 (D17C4) Rabbit mAb (Mouse Preferred)

Catalog Number:

3498S

Info: View Product View Product Specs

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The aim of the research was to measure Bcl-2 levels in primary mouse T cells after 24h of treatment by Western blot. For this experiment, we took primary T cells from mice and treated them with increasing concentrations of dexamethasone (0, 1,10,100, and 1000) to determine whether Bcl-2 was being regulated.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Primary Mouse T cells

Primary Incubation

1:4000, overnight, rocking, 4 degrees

Blocking Agent

10% Milk

Secondary Incubation

1:10,000 in 5% milk, 30 min

Tertiary Incubation

No tertiary incubation

Detection

Chemiluminescence

Results Summary

Clear bands

Additional Notes

None

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Summary

The Good

Easy to optimize

The Bad

Nothing negative to comment

The Bottom Line

Reliable antibody for the detection of Bcl-2

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