Product Reviews

We work on using stem cells to model and treat rare pediatric diseases, especially demyelinating diseases. We differentiate patient-derived ... Read Review

I study NPC1 and NPC2 in the context of Niemann–Pick type C disease and cholesterol trafficking. I used this NPC2 antibody to investigate ... Read Review

I study gene signaling pathways and use ß-catenin to investigate cell adhesion and Wnt signaling. This monoclonal antibody is useful for ... Read Review

P-glycoprotein (P-gp) expression was confirmed by ICC-IF in human brain microvascular endothelial cells. Previous qRT-PCR analysis detected ... Read Review

We use Phalloidin (Orange-red; Alexa Fluor™ 568) to stain the F-actin fibers in human brain microvascular endothelial cells (HBMECs), before... Read Review

We edit endogenous pathway genes using Cas9 RNP electroporation and synthesize sgRNAs in-house by in vitro transcription. I use the Qiagen ... Read Review

CellMask Green was used to stain the plasma membrane of live primary human brain microvascular endothelial cells (HBMECs). Read Review

C/EBPß is an important transcriptional regulator of cellular senescence and is frequently induced or activated in response to senescence-... Read Review

I used the Cell Signaling Technology BCL9 Antibody to examine the subcellular distribution of endogenous BCL9 during WNT3A stimulation. Read Review

I used the Cell Signaling Technology ß-TrCP antibody to detect ß-TrCP in ß-catenin immunoprecipitates. Read Review

I use the Omega Bio-tek Mag-Bind® Blood & Tissue DNA HDQ 96 Kit to extract genomic DNA from the screened cell populations. Read Review

I used the Cell Signaling Technology E-Cadherin antibody to detect E-cadherin in ß-catenin immunoprecipitates from wild-type and CTNNB1-null... Read Review

I used the Cell Signaling Technology Dvl2 Antibody to examine the subcellular distribution of endogenous DVL2 during WNT3A stimulation. Read Review

Although none of the T cell activation markers is perfect, we needed to at least have reliable antibodies to stain for such markers. CD25 (... Read Review

I study gene signaling pathways and use mScarlet-tagged proteins to investigate protein abundance and interactions. Read Review

We routinely use GoldBio Agarose LE (Cat# A-201-500) to resolve PCR amplicons and restriction digestion products. Read Review

My lab studies the molecular mechanisms of oncogenic WNT signal transduction, with the goal of identifying therapeutic vulnerabilities in ... Read Review

The Thermo Forma Direct Heat CO2 Incubator was used as a reliable and practical instrument for routine cell culture work. The temperature ... Read Review

Dynabeads Protein A provide a simple and efficient magnetic-bead platform for antibody-based protein capture. Read Review

These precast Wedge-well gels provide a convenient way to load more sample volume. Read Review

This kit provides a simple and efficient way to recover clean DNA from agarose gels. Read Review

In my lab, I use the Pierce BCA Protein Assay Kit to measure protein concentrations in whole-cell extracts and, occasionally, purified ... Read Review

This antibody has been a dependable reagent for monitoring endogenous NPC1 expression. It consistently delivers specific, reproducible ... Read Review

I regularly express and purify GST-tagged proteins for biochemical studies. This glutathione agarose resin provides a straightforward ... Read Review

The Alexa 700 anti-mouse CD90.2 antibody (clone 30-H12, BioLegend) provides a quite strong and reliable staining of T cells in mouse colonic... Read Review