Anti-CD279 antibodies enable researchers to detect and measure the CD279 antigen in biological samples. This target is a reported synonym of the PDCD1 gene, which encodes programmed cell death 1. This protein is known to function in adaptive immune responses and the apoptotic pathway, among other biological roles. The human version of CD279 has a canonical amino acid length of 288 residues and a protein mass of 31.6 kilodaltons. It is reported to be localized in the cell membrane of cells and notably expressed in the lymph node and tonsil. The CD279 marker has been described in the characterization of T Follicular Helper Cells and T Follicular Regulatory Cells.* Other names for this target antigen include PD-1 and PD1.
*HuBMAP Human Reference Atlas v1.4