Anti-KDR antibodies are used in the immunodetection of the protein kinase insert domain receptor. In humans, the canonical protein has a reported length of 1356 amino acid residues and a mass of 151.5 kDa. Its subcellular localization is in the cytoplasmic vesicles, ER, and cell membrane. Up to 3 different isoforms have been reported for this protein. It is notably expressed in cornea. A member of the Tyr protein kinase protein family, KDR is reported to be a tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Synonyms for this target antigen include FLK1, VEGFR, VEGFR2, vascular endothelial growth factor receptor 2, fetal liver kinase-1, and CD309. KDR gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 3000 citations in the literature describe the use of KDR antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Flow Cytometry, and Immunohistochemistry are also common applications.