Anti-VEGF Receptor 2 antibody ab2349 from Abcam

Product Specs
ItemAnti-VEGF Receptor 2 antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab2349
Antibody TypePrimary
ApplicationsImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ClonalityPolyclonal
HostRabbit
Quantity500 UL
IsotypeIgG
Conjugate/TagUnconjugated
Concentration0.5 mg/ml
Research AreaImmuno-oncology
Gene NameKDR
ReactivityHuman
TargetVEGF Receptor 2

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Exosomal circCOL1A1 promotes angiogenesis via recruiting EIF4A3 protein and activating Smad2/3 pathway in colorectal cancerMolecular MedicineNovember 8, 2023Gui Hu, Changwei Lin, Kai Gao, Miao Chen, Fei Long, Buning Tiananti-E-cadherin (ab231303, Abcam), anti-N-cadherin (ab76011, Abcam), anti-CD31 (ab124432, Abcam) and anti-VEGFR (ab2349, Abcam). Statistical analysis Data were presented as mean ± standard deviation (SD). All experiments

(2) Toceranib phosphate and firocoxib-mediated partial response in a dog with advanced intranasal sarcomaJournal of Veterinary Medical ScienceSeptember 20, 2023Hironari OSADA, Taiga OKAZAWA, Kazuya KUSHIDA, Miori KISHIMOTO, Mitsuhiro IKEDA, Hirotaka KONDO, Junpei KIMURA, Keitaro OHMORIanti-human,Monoclonal (28E1),1:100,"Cell Signaling Technology, Danvers, MA, USA" VEGFR2,Rabbit anti-human,Polyclonal (ab2349),1:100,"Abcam, Cambridge, UK" COX-2,Mouse anti-human,Monoclonal (33/Cox-2),1:100,"BD Biosciences, Franklin

(3) Dual gene‐activated dermal scaffolds regulate angiogenesis and wound healing by mediating the coexpression of VEGF and angiopoietin‐1Bioengineering & Translational MedicineSeptember 1, 2023Tingting Weng, Min Yang, Wei Zhang, Ronghua Jin, Sizhan Xia, Manjia Zhang, Pan Wu, Xiaojie He, Chunmao Han, Xiong Zhao, et al.with anti‐CD31 (1:200, ab222783, Abcam), anti‐α‐SMA (1:200, ab7817, Abcam) and anti‐VEGFR‐2 (1:200, ab2349, Abcam) primary antibodies at 4°C overnight. After sections had been washed three times with PBS, they

(4) Camrelizumab combined with apatinib in patients with first-line platinum-resistant or PD-1 inhibitor resistant recurrent/metastatic nasopharyngeal carcinoma: a single-arm, phase 2 trialNat CommunAugust 14, 2023Li Yuan, Guo-Dong Jia, Xiao-Fei Lv, Si-Yi Xie, Shan-Shan Guo, Da-Feng Lin, Li-Ting Liu, Dong-Hua Luo, Yi-Fu Li, Shen-Wen Deng, et al.CD3 (ZM-0417 ZSbio Clone: LN10); Eomes (ab183991, Abcam, 1:200); α-SMA (ab7817, Abcam, 1μg/mL); KDR (ab2349, Abcam, 1:100); PD-L1 (ab205921, Abcam, 2μg/mL); CD31(ab28364, Abcam, 1:50); IL8 (94407 T, Cell Signaling

(5) Immunomagnetic Delivery of Adipose-Derived Endothelial Progenitor Cells for the Repair of Renal Ischemia–Reperfusion Injury in a Rat ModelBioengineering (Basel)April 24, 2023Di Wu, Jingyu Liu, Changcheng Zhou, Wenjie Ma, Liuhua Zhou, Yuzheng Ge, Ruipeng Jiaanti-CD34 (ab81289, Abcam, Cambridge, UK), anti-CD133 (ab19898, Abcam, Cambridge, UK), and anti-VEGFR2 (ab2349, Abcam, Cambridge, UK). After washing three times with PBS and incubating with Alexa Fluor 488 or 555

(6) Knockdown SENP1 Suppressed the Angiogenic Potential of Mesenchymal Stem Cells by Impacting CXCR4-Regulated MRTF-A SUMOylation and CCN1 ExpressionBiomedicinesMarch 15, 2023Rui Zhang, Qingxi Liu, Cuicui Lyu, Xing Gao, Wenjian Mawith normal goat serum for 30 min at room temperature. After incubation with rabbit anti-KDR (Abcam, ab2349) and anti-MRTF-A (Abcam, ab219981) in a humid chamber overnight, cells were incubated with appropriate

(7) Investigation of SAMD1 ablation in miceScientific ReportsFebruary 21, 2023Bruce Campbell, Lisa M. Weber, Sandra J. Engle, Terence R. S. Ozolinš, Patricia Bourassa, Robert Aiello, Robert Liefkewas stained with hematoxylin and eosin (H&E). Other slices were stained for CD31 (ab28364) or VEGFR2 (ab2349) with hematoxylin counterstaining following Abcam’s protocols. Cell culture E14 mESCs (E14TG2a) were

(8) CD34(dim) cells identified as pluripotent stem cell-derived definitive hemogenic endothelium purified using bone morphogenetic protein 4Cell proliferationFebruary 1, 2023Jeon SB, Han AR, Lee S, Lee SC, Lee MJ, Park SJ, Moon SH, Lee JY.rabbit anti‐human Runt‐related transcription factor 1 (RUNX1; ab35962), rabbit anti‐human FLK‐1 (KDR) (ab2349), mouse anti‐human CD71 (ab9179), rabbit anti‐human CD235a (ab129024), mouse anti‐human CD105 (ab230925),

(9) Vascular endothelial growth factor receptor 2 expression and immunotherapy efficacy in non–small cell lung cancerCancer ScienceSeptember 1, 2022Kenji Nakahama et al.(pH 6.0) for 20 minutes at 100°C. The sections were stained with an anti‐VEGFR2 antibody (polyclonal, ab2349, 1:200; Abcam, RRID: AB_302998) at 4°C overnight. Mouse skin tissue was used as the positive control.

(10) Protective role of VEGF/VEGFR2 signaling against high fatality associated with hepatic encephalopathy via sustaining mitochondrial bioenergetics functionsJournal of biomedical scienceJuly 3, 2022Tsai CY, Wu JCC, Wu CJ, Chan SHH.carried out by incubation for 48 h at 4 °C using a rabbit polyclonal antiserum against VEGFR2 (1:250; #ab2349, Abcam, Cambridge, MA, USA) and a mouse monoclonal antiserum against β-Tubulin III (1:1000; #T8578,

(11) IL‐10 promotes endothelial progenitor cell infiltration and wound healing via STAT3The FASEB JournalJuly 1, 2022Walker D. Short, Emily Steen, Aditya Kaul, Xinyi Wang, Oluyinka O. Olutoye, Hima V. Vangapandu, Natalie Templeman, Alexander J. Blum, Chad M. Moles, Daria A. Narmoneva, et al.of Fab to antibody target was used for CD133 (AbCam ab19898), and 6:1 molar ratio for FLK‐1 (AbCam, ab2349). The CD133‐488 complex was diluted 1:250, while the FLK‐1‐647 complex was diluted 1:25 in block and

(12) Comparison of vascular endothelial growth factor/vascular endothelial growth factor receptor 2 expression and its relationship to tumor cell proliferation in canine epithelial and mesenchymal tumorsJournal of Veterinary Medical ScienceJanuary 24, 2022Mayu KIMURA, Kaede MIYAHARA, Masahiro YAMASAKI, Naohiro UCHIDAanti-VEGF monoclonal antibody (1:100, ab1316; Abcam), rabbit anti-VEGFR2 polyclonal antibody (1:100, ab2349; Abcam), and rabbit anti-phospho-VEGFR2 antibody (1:250, MBS462155; MyBiosource, Nagoya, Japan) diluted

(13) Swimming attenuates tumor growth in CT-26 tumor-bearing mice and suppresses angiogenesis by mediating the HIF-1α/VEGFA pathwayOpen life sciencesJanuary 1, 2022Li J, Liu L, Cheng Y, Xie Q, Wu M, Chen X, Li Z, Chen H, Peng J, Shen A.GTX127309) was provided by GeneTex Inc. (San Antonio, TX, USA). VEGFA (Cat no. ab1316), VEGFR2 (Cat no. ab2349), and CD31 (Cat no. ab28364) antibodies were purchased from Abcam (Cambridge Science Park, Cambridge,

(14) Radix Astragalus Polysaccharide Accelerates Angiogenesis by Activating AKT/eNOS to Promote Nerve Regeneration and Functional RecoveryFrontiers in pharmacologyJanuary 1, 2022Zhang G, Huang J, Hao S, Zhang J, Zhou N.Abcam, ab52642), CD31 (1:200, Abcam, ab182981), CD34 (1:200, Abcam, ab81289), VEGFR (1:200, Abcam, ab2349), AKT (1:100, Abcam, ab179463), p-AKT (1:100, Abcam, ab192623), eNOS (1:100, ThermoFisher, PA1-037),

(15) Recombinant nanobody against MUC1 tandem repeats inhibits growth, invasion, metastasis, and vascularization of spontaneous mouse mammary tumorsMolecular OncologyJanuary 1, 2022Parnaz Merikhian et al.inducing angiogenesis and metastasis; anti‐VEGF receptor 2 (VEGFR2) monoclonal antibody (Catalog number: ab2349, Abcam), a receptor with pro‐angiogenic activity upon stimulation; anti‐CD31/platelet endothelial cell

(16) Engineered hypoxia-responding Escherichia coli carrying cardiac peptide genes, suppresses tumor growth, angiogenesis and metastasis in vivoJournal of Biological EngineeringDecember 1, 2021Mitra Samadi, Keivan Majidzadeh-A, Malihe Salehi, Neda Jalili, Zeinab Noorinejad, Marjan Mosayebzadeh, Ahad Muhammadnejad, Azadeh Sharif khatibi, Shima Moradi-Kalbolandi, Leila Farahmandenzyme involved in inducing angiogenesis and metastasis; anti-VEGF receptor 2 monoclonal antibody (ab2349, Abcam, USA), a proangiogenic growth factor; anti-CD31/PECAM-1 monoclonal antibody (ab24590, Abcam,

(17) Effect of endothelial progenitor cell-derived extracellular vesicles on endothelial cell ferroptosis and atherosclerotic vascular endothelial injuryCell Death DiscoveryDecember 1, 2021Lin Li, Haining Wang, Jing Zhang, Xiao Chen, Zhongwang Zhang, Qiang Li(ab110643, Abcam Inc., Cambridge, MA, USA), CD133 (ab222782, Abcam), vWF (ab6994, Abcam), and VEGF-2 (ab2349, Abcam) at 4 °C overnight. Then, the cells were added with TRITC-labeled fluorescent secondary antibody

(18) LINC00261 elevation inhibits angiogenesis and cell cycle progression of pancreatic cancer cells by upregulating SCP2 via targeting FOXP3Journal of cellular and molecular medicineOctober 1, 2021Zou J, Pei X, Xing D, Wu X, Chen S.incubated with 50 μl of rabbit anti‐mouse antibodies to CD31 (1: 100, ab28364, Abcam), VEGF (1: 100, ab2349, Abcam) and Brachyury (1: 100, ab140661, Abcam) overnight at 4℃. PBS was used as the primary antibody

(19) Effective Actions of Ion Release from Mesoporous Bioactive Glass and Macrophage Mediators on the Differentiation of Osteoprogenitor and Endothelial Progenitor CellsPharmaceuticsJuly 27, 2021Alberto Polo-Montalvo, Laura Casarrubios, María Concepción Serrano, Adrián Sanvicente, María José Feito, Daniel Arcos, María Teresa Portolésab81289, Abcam, UK), anti-eNOS (M221, ab76198, Abcam, UK), anti-vWF (ab6994, Abcam, UK), and anti-VEGFR2 (ab2349, Abcam, UK). Two secondary antibodies were used conjugated with either DyLight 633 (IgG (H + L) goat

(20) EPC-Derived Exosomal miR-1246 and miR-1290 Regulate Phenotypic Changes of Fibroblasts to Endothelial Cells to Exert Protective Effects on Myocardial Infarction by Targeting ELF5 and SP1Frontiers in Cell and Developmental BiologyMay 13, 2021Yulang Huang, Lifang Chen, Zongming Feng, Weixin Chen, Shaodi Yan, Rongfeng Yang, Jian Xiao, Jiajia Gao, Debao Zhang, Xiao Ke(ab32575, 1:3,000, Abcam), CD31 (ab24590, 1:500, Abcam), VE-cadherin (ab166715, 1:1,000, Abcam), VEGFR2 (ab2349, 1:400, Abcam), ELF5 (ab222251, 1:1,000, Abcam), SP1 (ab227383, 1:5,000, Abcam), Lamin A (ab26300, 1:1,000,

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Anti-VEGF Receptor 2 antibody from Abcam

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Anti-VEGF Receptor 2 antibody from Abcam

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