Anti-tubulin alpha 4a antibodies are used for the immunodetection of the protein encoded by the TUBA4A gene. In humans, the canonical protein has a reported length of 448 amino acid residues and a mass of 49.9 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Tubulin protein family, it is known to be involved with cytoskeleton organization and the cell cycle. Post-translational modifications have been described, including acetylation. Other names for this target antigen include H2-ALPHA, TUBA1, tubulin alpha-4A chain, tubulin H2-alpha, tubulin alpha-1 chain, and ALS22. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species. Over 10000 citations in the literature describe the use of tubulin alpha 4a antibodies in research. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.