Anti-mTOR antibodies are useful for applications like western blot, immunofluorescence, and flow cytometry for the measurement of the target protein 'mechanistic target of rapamycin kinase,' which is encoded by the MTOR gene in humans. Orthologs for MTOR have also been reported in other species, including mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken. The canonical mTOR protein is 2549 amino acids in length, 288.9 kDa in mass, and has a nuclear, cytoplasmic, mitochondrial, ER, Golgi and lysosomal subcellular localization. It is a member of the PI3/PI4-kinase protein family. mTOR functions in protein binding and ATP binding, as well as having a role in the adaptive immune system, signal transduction, and cellular stress response. It is widely expressed across many tissues. Post-translational modifications have been described, notably phosphorylation.