Anti-CD117 antibodies are protein reagents that detect specific antigens. The CD117 antigen is another term for the human protein KIT proto-oncogene, receptor tyrosine kinase, encoded by the KIT gene. The protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Canonically, it has an amino acid length of 976 residues and a mass of 109.9 kilodaltons. Its subcellular localization is in the cell membrane and cytoplasm and it is expressed in many tissues, such as the cerebellum and skin. The CD117 protein is a member of the Tyr protein kinase protein family. Other alias names for CD117 include C-Kit and C-Kit.