Anti-CCR6 antibodies are essential reagents in flow cytometry for detecting the target protein, C-C motif chemokine receptor 6. CCR6 serves as a surface receptor for the chemokine CCL20, whose binding leads to increased intracellular calcium ion levels. It can also act as a receptor for non-chemokine ligands such as beta-defensins. It localizes to the cell membrane. It is used as a phenotypic marker in distinguishing populations of T lymphocytes and NK T cells. Examine the supplier's provided validation data when comparing CCR6 antibodies for flow cytometry. Also look for application-specific recommendations, such as dilutions, protocols, sample types, and other helpful usage notes.