CCR6 Antibody MAB590-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCCR6 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB590-100
Quantity100 ug (also 25 ug)
ApplicationsFlow Cytometry, Immunohistochemistry, CyTOF-ready
Conjugate/TagUnconjugated
ReactivityMouse
TargetCCR6
IsotypeIgG2a
Clone140706
HostRat
NCBI Full Gene Namechemokine (C-C motif) receptor 6
NCBI Gene AliasesCC-CKR-6, CCR-6, KY411, Cmkbr6
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenRBL-1 rat basophilic leukemia cell line transfected with mouse CCR6, Met1-Met367, Accession # O54689
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse CCR6-transfected rat RBL cells but not the parent cell line or cells transfected with mouse CCR5

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) IL-1β and IL-23 Promote Extrathymic Commitment of CD27⁺CD122^- γδ T Cells to γδT17 CellsJournal of immunology (Baltimore, Md. : 1950)October 15, 2017Muschaweckh A, Petermann F, Korn T.

(2) IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require α4β1 Integrin To Migrate between the Peritoneum and Inflamed SkinJournal of immunology (Baltimore, Md. : 1950)March 15, 2016Geherin SA, Gómez D, Glabman RA, Ruthel G, Hamann A, Debes GF.

(3) The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophagesMolecular cancerJune 6, 2015Boyle ST, Faulkner JW, McColl SR, Kochetkova M.

(4) SerpinB1 regulates homeostatic expansion of IL-17+ γδ and CD4+ Th17 cellsJournal of leukocyte biologyMarch 1, 2014Zhao P, Hou L, Farley K, Sundrud MS, Remold-O'Donnell E.

(5) CCR6 is a prognostic marker for overall survival in patients with colorectal cancer, and its overexpression enhances metastasis in vivoPloS oneJanuary 1, 2014Liu J, Ke F, Xu Z, Liu Z, Zhang L, Yan S, Wang Z, Wang H, Wang H.

(6) Colonic patch and colonic SILT development are independent and differentially regulated eventsMucosal immunologyMay 1, 2013Baptista AP, Olivier BJ, Goverse G, Greuter M, Knippenberg M, Kusser K, Domingues RG, Veiga-Fernandes H, Luster AD, Lugering A, et al.

(7) Programmed downregulation of CCR6 is important for establishment of epidermal γδT cells by regulating their thymic egress and epidermal locationJournal of immunology (Baltimore, Md. : 1950)April 1, 2013Hu S, Xiong N.

(8) CCR6 is required for epidermal trafficking of γδ-T cells in an IL-23-induced model of psoriasiform dermatitisThe Journal of investigative dermatologyJanuary 1, 2013Mabuchi T, Singh TP, Takekoshi T, Jia GF, Wu X, Kao MC, Weiss I, Farber JM, Hwang ST.

(9) Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2Journal of immunology (Baltimore, Md. : 1950)June 15, 2010Röhrl J, Yang D, Oppenheim JJ, Hehlgans T.

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(1)

1/26/2018Mouse CCR6 Antibody Jeeho LeeThe aim was to study T cell trafficking. The specific goal was to examine the expression of CCR6 chemokine receptor (mainly expressed by Th17 cells) by CD4 T cells. I selected this product because it ... Read Review

CCR6 Antibody

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CCR6 Antibody

CCR6 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (9)

Reviews

CCR6 Antibody from R&D Systems, a Bio-Techne Brand

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