Raffaele Bellini

M.D. Anderson

Effective Reducing Agent From Sigma Aldrich
July 23, 2023
This product was used to reduce ester to aldehydes avoiding the risk to get the corresponding alcohol read more
Trifluoroacetic Acid for Boc Deprotection From Oakwood Chemical
July 23, 2023
The goal of the work was to remove the Boc protective group from an amide to go further in the synthesis, following a coupling ... read more
Trifluoroacetic Acid From Thermo Scientific For Boc Deprotection
July 23, 2023
We need to deprotect a Boc amine to be able then to link it to a carboxylic acid and form a new peptide bond. read more
Di-tert-butyl dicarbonate for Boc Protection
July 23, 2023
The aim was to protect just one side of a diamine to be subsequently able to link it to a second scaffold. read more
Synthesis of Schiff Base
July 23, 2023
We synthesized a Schiff base using an amine and an aldehyde. This product will be then linked to a larger scaffold exploiting the ... read more
Acid Catalyzed Reaction with Titanium (III) Chloride
June 01, 2023
We tried to get a intramolecular cyclization using TiCl3 as catalyst. Its purpose was to activate the carboxylic functional moiety... read more
Bulky Base Works Well for Deprotonation
May 12, 2023
Synthesis of new peptide bond starting from an acyl chloride and an amide in a dry atmosphere of N2, using bulky base. read more
Hygroscopic Methanol-d4 for NMR Spectra
May 12, 2023
At the end of a synthesis of a compound, you need to check if the reaction has gone to the right way or not. Several method can be... read more
Deprotonation of Mild Acid Protons with Butyllithium
May 09, 2023
The product has been used to deprotonate protons with high pKa that are not possible to deprotonate with more mild bases. read more
Ester Reduction with Methyl 4-Bromophenylacetate
May 09, 2023
The corresponding aldehyde will be used to form a bicycle, where the aldehydic moiety will react to form part of the ring ... read more
Synthesizing New Peptide Bond with Acryloyl Chloride
May 04, 2023
Synthesis of new peptide bond starting from acyl chloride and an amine. I used 1 equivalent added at 0 °C and then brought to room... read more
Chloroform-d Works Well for NMR Spectra
April 25, 2023
After the end of any reaction, there are several methods that can be used to check if it is gone to the right way or not. One of... read more
Effective Tetrahydrofuran for Dry Synthesis
April 25, 2023
I used the THF extra dry at a C=0.5 M for the dehydrogenation of a secondary amide. The reaction worked fast, It needed 30 minutes... read more

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Excellent Astrocyte Labeling with Low Background in Mouse Hippocampus

Ksenia Novototskaya

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We used this antibody to immunofluorescently label astrocytes in the mouse dorsal hippocampus following astrocyte-specific MOR knockdown. The signal was bright,... read more

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