Synthesis of Schiff Base

M.D. Anderson

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Quality of Results

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Company:

Sigma Aldrich

Product Name:

2,2-dimethyl-1,3-propanediamine

Catalog Number:

226920

Info: Supplier Page 

We synthesized a Schiff base using an amine and an aldehyde. This product will be then linked to a larger scaffold exploiting the imine moiety.

Experimental Design and Results Summary

Application

Synthesis of Schiff base

Starting Material

N/A

Tips

Note that it is corrosive, and flammable.

Results Summary

After protecting just one of the amine, we were able to link the compound to and aldehyde using 1 equivalent of the amine and 1 equivalent of the aldehyde in just 3 hours at 70 °C.

DOI or PMID #

N/A

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Summary

The Good

Affordable and easy to handle.

The Bad

None.

The Bottom Line

It is not too expensive and worked well for my project. I would recommend it.

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