Sigma Aldrich
Titanium (III) Chloride
14010
Info:Supplier Page
We tried to get a intramolecular cyclization using TiCl3 as catalyst. Its purpose was to activate the carboxylic functional moiety of the structure.
Catalyst
N/A
Corrosive
We the aid of the Titanium, we could decrease the energy of the transition state to reach the cyclo-cheton structure. Equivalents = 4.5. Needed to be added dropwise.
Works well, stable for long periods.
I would suggest its use for anyone who needs to activate a carboxylic or carbonyl moiety.