Anti-CD38 antibodies are used in applications like western blot, immunofluorescence, and immunocytochemistry for the detection of the target antigen which is encoded by the gene, CD38 molecule (CD38), in humans. Orthologs for CD38 have also been reported in other species, including mouse, rat, bovine, frog, chimpanzee and chicken. The canonical CD38 protein is 300 amino acids in length, 34.3 kDa in mass, and has a membrane subcellular localization. It is a member of the ADP-ribosyl cyclase protein family. CD38 functions in NAD(P)+ nucleosidase activity and identical protein binding, as well as having a role in the apoptotic signaling pathway and artery smooth muscle contraction. Expression of CD38 is known in the blood and in several tissues, including brain, kidney, liver, testis, placenta and pancreas. It is a common marker for various lymphocytes. Synonyms for this protein include: ADPRC 1; ADPRC1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase.