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APC/Cy7 anti-human CD38 Antibody
303533
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Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease. Here, we aimed at staining Plasmablasts (CD38+CD27+) in isolated PBMCs from peripheral blood of a healthy donor (HD).
Flow Cytometry
Isolated PBMCs from HD peripheral blood
Anti-CD38 APC-Cy7
Fc block
N/A
Flow Cytometer
There is background staining, but Plamablasts (PB) can be identified as CD38+CD27++.
It is useful
Background staining
It can be used, if in combination with other marker.