Anti-IDH1 antibodies are used in the immunodetection of the protein isocitrate dehydrogenase (NADP(+)) 1. In humans, the canonical protein has a reported length of 414 amino acid residues and a mass of 46.7 kDa. Its subcellular localization is in the cytoplasm. It is notably widely expressed in many tissue types. A member of the Isocitrate and isopropylmalate dehydrogenases protein family, IDH1 is known to catalyze the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Synonyms for this target antigen include HEL-S-26, IDCD, IDH, IDP, IDPC, PICD, isocitrate dehydrogenase [NADP] cytoplasmic, and HEL-216. IDH1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 300 citations in the literature describe the use of IDH1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.