IDH1 (D2H1) Rabbit mAb 8137S from Cell Signaling Technology

Product Specs
ItemIDH1 (D2H1) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8137S
Quantity100 µl
ApplicationsW, IP, IF-IC, FC-FP
ReactivityH, M, R, Mk
TargetIDH1
IsotypeIgG
Molecular Weight46
CloneD2H1
HostRabbit
NCBI Full Gene Nameisocitrate dehydrogenase (NADP(+)) 1
NCBI Gene AliasesHEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC, PICD
ClonalityMonoclonal
Research AreaMetabolism

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) CBFA2T2: a novel H3K27 reader regulating metabolism and tumor growthMolecular CancerFebruary 17, 2026Shengfei He, Yutian Ou, Fangfang Jiao, Jiuxing Feng, Ping Zhu, Jie Ma, Ning Xu, Haitao Li, Rui Guo,Cell Signaling Technology); UTX (1:1000;# 33510,Cell Signaling Technology); KDM6B (1:1000;# A12763,ABclonal); IDH1 (1:1000; # 8137,Cell Signaling Technology); IDH2 (1:1000;#56439,Cell Signaling Technology); OGDH (1:1000;# 15212-1-AP,

(2) Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant GliomaAdvanced ScienceJanuary 1, 2026Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, et al.western blots are as follows: IDH1R132H (Dianova, DIA‐H09, 1:500); IDH1(D2H1)(Cell Signaling Technology, 8137, 1:1000); β‐actin (Proteintech, 10004413, 1:1000); Vinculin (Sigma‐Aldrich, V4505, 1:5000); phospho‐VEGFR2

(3) Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastomaNature CommunicationsNovember 25, 2025Bethany Veo, Dong Wang, John DeSisto, Angela Pierce, Breauna Brunt, Pradeep Chandra Bompada, Andrew Donson, Andrew Goodspeed, Kiara Smart, Nicholas Foreman, et al.total protein was separated on a 4-20% gradient SDS-PAGE (BioRad). Primary antibodies α-IDH1 1:1000 (#8137), α-H3K27me3 1:1000 (#9733), α-H3K27ac 1:1000 (#8173), and α-H3 1:1000 (#9715) (Cell Signaling Technology)

(4) Senescent Fibroblasts Drive Melanoma Progression Through GCP ‐2 Induced CREB Phosphorylation Enhancing GlycolysisAging CellNovember 19, 2025Abhijit Basu, Vida Farsam, Karmveer Singh, Diana Crisan, Nicolai Treiber, Lars Alexander Schneider, Margit Huber, Jennifer I. Engelmeyer, Björn Schumacher, Pallab Maity, et al.purchased from Millipore and (HexI #2024; Hex II #2867; pPFKFB2 #13064; G3PDH #2118; PDH #3205; IDH1 #8137, IDH2 #12652; OGDH #13407; GDH1/2 #12793; SDH #11998; FH #4567; Cell Signalling Technologies) were diluted

(5) Opposing lineage specifiers induce a protumor hybrid identity state in lung adenocarcinomaGenes & DevelopmentSeptember 2, 2025Gabriela Fort, Henry Arnold, Soledad A. Camolotto, Kayla O'Toole, Rushmeen Tariq, Anna Waters, Katherine Gillis, Eric L. SnyderCell Signaling Technology 4696; RRID: AB_390780), ALDOB (1:1000; Abcam ab153828), IDH1 (1:1000; Cell Signaling Technology 8137; RRID: AB_10950504), Galectin-4 (1:1000; R&D Systems AF2128; RRID: AB_2297050), HOPX (1:1000; Abcam

(6) Sphingosine 1-phosphate derived from tumor-educated hepatic stellate cells combining with S1PR4 promotes tumor associated macrophages differentiation through FAO modulationSci RepJuly 1, 2025Rui Feng, Zilin Cui, Long Yang, Zirong Liuincubated with primary antibodies, specifically ACAA1 (44,276), ALOX5 (3289), CPT2 (52,552), IDO1 (8137), BAX (2772), Bcl2 (15,071), Caspase3 (6992), SphK1 (12,071), α-SMA (19,245), Vimentin (5471), Nrf2

(7) Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosisCancer CellJune 9, 2025Derek Dang, Akash Deogharkar, John McKolay, Kyle S. Smith, Pooja Panwalkar, Simon Hoffman, Wentao Tian, Sunjong Ji, Ana P. Azambuja, Siva Kumar Natarajan, et al.Active Motif), anti-GAPDH (2118, Cell Signaling Technology), anti-PDHB (PA5-27989, Invitrogen), anti-IDH1 (8137, Cell Signaling Technology), anti-BMI1 (5856, Cell Signaling Technology), anti-C-MYC (ab32072, Abcam),

(8) Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesityMolecular CellJune 5, 2025Tigist Y. Tamir, Shreya Chaudhary, Annie X. Li, Sonia E. Trojan, Cameron T. Flower, Paula Vo, Yufei Cui, Jeffrey C. Davis, Rachit Mukkamala, Francesca N. Venditti, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies GSTP1 (3F2) Mouse mAb,Cell Signaling Technology,3369 IDH1 (D2H1) Rabbit mAb,Cell Signaling Technology,8137 HA-Tag (6E2) Mouse mAb,Cell Signaling Technology,2367 PCNA (PC10) Mouse mAb,Cell Signaling Technology,2586 Rabbit anti-UMPS Antibody Affinity Purified

(9) Ethylene‐Activated E3 Ubiquitin Ligase MdEAEL1 Promotes Apple Fruit Softening by Facilitating the Dissociation of Transcriptional Repressor ComplexesAdvanced ScienceApril 9, 2025Tong Li, Li Liu, Guangxin Yang, Yingcong Cai, Yingda Wang, Bowen Sun, Le Sun, Weiting Liu, Aide Wangusing anti‐GFP, anti‐H3K9Ac (Cat. no. 9649, Cell Signaling Technologies), or anti‐H3K27Ac (Cat. no. 8137, Cell Signaling Technologies) antibody. The amount of immunoprecipitated chromatin was measured using

(10) RNF7‐Mediated ROS Targets Malignant Phenotype and Radiotherapy Sensitivity in Glioma With Different IDH1 GenotypesMolecular CarcinogenesisJanuary 9, 2025Yiran Tao, Zimin Shi, Xianyin Liang, Yuqian Zheng, Lirui Dai, Xiang Li, Zian Li, Wulong Liang, Gaojie Bai, Hao Li, et al.dilution, 1:1000; cat. no. 13110S; Cell Signaling Technology Inc.), anti‐IDH1 (dilution, 1:1000; cat. no. 8137; Cell Signaling Technology), anti‐IDH1‐R132H (dilution, 1:1000; cat. no. DIA‐HO9‐M; Dianova), anti‐γH2A.X

(11) Endogenous histidine peptides are physiological antioxidants that prevent oligodendrocyte cell death and myelin loss in vivoGliaJanuary 1, 2025Sajrawi C, Odeh M, Tiwari AK, Agranovich B, Abramovich I, Zubedat S, Saar G, Shaulov L, Avital A, Reznik D, et al.monoclonal",Cell Signaling Technology,#64414 "Anti-IDH1, rabbit monoclonal",Cell Signaling Technology,#8137 "Anti-Hexokinase1, rabbit monoclonal",Abcam,ab150423 "Anti-Hexokinase2, rabbit monoclonal",Abcam,ab209847 "Anti-CNDP2,

(12) Imbalance of redox homeostasis and altered cellular signaling induced by the metal complexes of terpyridineScientific ReportsNovember 6, 2024Katarzyna Malarz, Patryk Ziola, Dawid Zych, Patryk Rurka, Anna Mrozek-Wilczkiewiczincubated with following primary antibodies: HIF-1α (#14179, Cell Signalling Technology - CST); IDH1 (#8137, CST); Nrf2 (#12721, CST); BID (#2002, CST); cdc2 (#9116, CST); cdc25c (#4688, CST); cyclin A2 (#4656,

(13) Compensatory activity of the PC-ME1 metabolic axis underlies differential sensitivity to mitochondrial complex I inhibitionNature communicationsOctober 7, 2024Del Prado L, Jaraíz-Rodríguez M, Agro M, Zamora-Dorta M, Azpiazu N, Calleja M, Lopez-Manzaneda M, de Juan-Sanz J, Fernández-Rodrigo A, Esteban JA, et al.anti MPC1 (1/1000) (14462; Proteintech); anti-PC (1/1000) (NBP-49536; Novus); anti-IDH1 (1/1000) (#8137; Cell Signaling); anti-B III tubulin (1/1000) (ab78078; Abcam); anti-B actin (1/2000) (A5441; Sigma);

(14) Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesitybioRxivSeptember 1, 2024Tigist Y Tamir, Shreya Chaudhary, Annie X Li, Sonia E Trojan, Cameron T Flower, Paula Vo, Yufei Cui, Jeffrey C Davis, Rachit S Mukkamala, Francesca N Venditti, et al.,Thermo Fisher Scientific,LC6060 Antibodies,, GSTP1,Cell Signaling Technology,3369 IDH1,Cell Signaling Technology,8137 HA,Cell Signaling Technology,2367 PCNA,Cell Signaling Technology,2586 UMPS,Bethyl/Fortis Life Sciences,A304-258A-M Vinculin,Millipore Sigma

(15) Metastatic breast cancer cells are metabolically reprogrammed to maintain redox homeostasis during metastasisRedox BiologySeptember 1, 2024Marco Biondini, Camille Lehuédé, Sébastien Tabariès, Matthew G. Annis, Alain Pacis, Eric H. Ma, Christine Tam, Brian E. Hsu, Yannick Audet-Delage, Afnan Abu-Thuraia, et al.ab138491, Abcam); anti-GR (1:1000 dilution) (Cat. #: ab137513, Abcam); anti-IDH1 (1:1000 dilution) (Cat. #: 8137, Cell Signaling); anti- xCT/SLC7A11 (1:1000 dilution) (Cat. #: 98051, Cel Signaling); anti-αTubulin

(16) Exploiting Metabolic Defects in Glioma with Nanoparticle-Encapsulated NAMPT InhibitorsMolecular Cancer TherapeuticsAugust 1, 2024Matthew A. Murray, Katelyn J. Noronha, Yazhe Wang, Anna P. Friedman, Sateja Paradkar, Hee-Won Suh, Ranjini K. Sundaram, Charles Brenner, W.M. Saltzman, Ranjit S. BindraTBS-T: PPM1D (SCBT F-10 sc-376257), GAPDH (Proteintech group HRP-60004), IDH1 (Cell Signaling Technology 8137S), IDH1-R132H (DIANOVA DIA-H09); 5% BSA in 1× TBS-T: NAPRT (Proteintech group 66159-1-Ig). Membranes

(17) Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic-mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancerMolecular oncologyOctober 1, 2023Gonthier K, Weidmann C, Berthiaume L, Jobin C, Lacouture A, Lafront C, Harvey M, Neveu B, Loehr J, Bergeron A, et al.used were from Abcam (Toronto, ON, Canada): IDH1 (ab172964); Cell Signaling (Danvers, MA, USA): IDH1 (8137), IDH2 (56439S), Citrate Synthase (14309), Tubulin (2125); and Santa Cruz Biotechnology (Santa Cruz,

(18) FASN deficiency induces a cytosol-to-mitochondria citrate flux to mitigate detachment-induced oxidative stressCell ReportsAugust 14, 2023Wenting Dai, Zhichao Wang, Guan Wang, Qiong A. Wang, Ralph DeBerardinis, Lei Jiang,Cell Signaling Technology,Cat#3189; RRID:AB_2100798 Rabbit monoclonal anti-IDH1(D2H1),Cell Signaling Technology,Cat#8137; RRID:AB_10950504 Rabbit polyclonal anti-CTP (T-16),Santa Cruz Biotechnology,Cat# sc-86392; RRID:AB_2189618 Rodent

(19) QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolismCellJuly 20, 2023Zhao Z, Qing Y, Dong L, Han L, Wu D, Li Y, Li W, Xue J, Zhou K, Sun M, et al.(A303-426A, Bethyl Laboratories), METTL3 (ab195352, Abcam), METTL14 (HPA038002, Sigma-Aldrich), IDH1 (8137S, Cell Signaling Technology), FLAG (F3165, Sigma-Aldrich), RPL7 (14583-1-AP, Proteintech), GSK3B (22104-1-AP,

(20) Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formationCell reportsJune 27, 2023Pathmanapan S, Poon R, De Renshaw TB, Nadesan P, Nakagawa M, Seesankar GA, Ho Loe AK, Zhang HH, Guinovart JJ, Duran J, et al.anti-HIF1A,Abcam,"ab1, RRID:AB_296474" Rabbit monoclonal anti-IDH1,Cell Signaling Technology,"Cat# 8137, RRID:AB_10950504" Rabbit polyclonal anti-IDH1,Thermo Fisher Scientific,"PA5–28206, RRID:AB_2545682" Rabbit

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IDH1 (D2H1) Rabbit mAb

IDH1 (D2H1) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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IDH1 (D2H1) Rabbit mAb from Cell Signaling Technology

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