Isocitrate Dehydrogenase 1/IDH1 Antibody MAB7049 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIsocitrate Dehydrogenase 1/IDH1 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB7049
Quantity100 ug (also 25 ug)
ApplicationsWestern Blot, Simple Western, Immunohistochemistry, Immunocytochemistry
Conjugate/TagUnconjugated
ReactivityHuman
TargetIsocitrate Dehydrogenase 1/IDH1
IsotypeIgG1
Clone843219
HostMouse
NCBI Full Gene Nameisocitrate dehydrogenase (NADP(+)) 1
NCBI Gene AliasesIDPC, IDP, HEL-S-26, PICD, IDH, HEL-216, IDCD
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenE. coli-derived recombinant human Isocitrate Dehydrogenase 1/IDH1, Ser2-Leu414, Accession # O75874
ConcentrationLYOPH
Brand/TrademarkR&D Systems, a Bio-Techne Brand
PurityProtein A or G purified from hybridoma culture supernatant
ValidationKnockout Validated
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human Isocitrate Dehydrogenase 1/IDH1 in ELISAs and Western blots

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) TNFα-induced IDH1 hyperacetylation reprograms redox homeostasis and promotes the chemotherapeutic sensitivityOncogeneJanuary 1, 2023Yang H, Zhao X, Liu J, Jin M, Liu X, Yan J, Yao X, Mao X, Li N, Liang B, et al.

(2) Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cellsCell chemical biologyJuly 21, 2022Zhang R, Chen D, Fan H, Wu R, Tu J, Zhang FQ, Wang M, Zheng H, Qu CK, Elf SE, et al.2019a)",Cat# N/A; Clone# N/A; RRID: N/A Human Isocitrate Dehydrogenase1/IDH1 Antibody,R&D SYSTEMS,Cat# MAB7049; Clone# 843219; RRID: AB_2811299 "Goat anti-Mouse IgG (H+L) Secondary Antibody, HRP",Thermo Fisher Scientific

(3) Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cellsMolecular cellSeptember 16, 2021Chen D, Xia S, Zhang R, Li Y, Famulare CA, Fan H, Wu R, Wang M, Zhu AC, Elf SE, et al.2019)",Cat# N/A;Clone# N/A;RRID: N/A Human Isocitrate Dehydrogenase1/IDH1 Antibody,R&D SYSTEMS,Cat# MAB7049;Clone# 843219;RRID: AB_2811299 Acetylated-Lysine Antibody,Cell Signaling Technology,Cat# 9441;Clone#

(4) Exosomal IDH1 increases the resistance of colorectal cancer cells to 5-FluorouracilJournal of CancerJanuary 1, 2021Yang H, Xie S, Liang B, Tang Q, Liu H, Wang D, Huang G.

(5) Metabolic Diversity in Human Non-Small Cell Lung Cancer CellsMolecular cellDecember 5, 2019Chen PH, Cai L, Huffman K, Yang C, Kim J, Faubert B, Boroughs L, Ko B, Sudderth J, McMillan EA, et al.,Cell signaling,3777P Brdu,ThermoFisher,BDB347583 IDH1,"Shanghai Genomics, Inc.",N/A p-IDH1 (Y42),"Shanghai Genomics, Inc.",N/A p-IDH1 (Y391),R & D Systems,Cat# MAB7049 "Chemicals, Peptides, and Recombinant Proteins","Chemicals, Peptides, and Recombinant Proteins","Chemicals,

(6) Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in CancerCancer discoveryJune 1, 2019Chen D, Xia S, Wang M, Lin R, Li Y, Mao H, Aguiar M, Famulare CA, Shih AH, Brennan CW, et al.

Be the First to Write a Review!

Isocitrate Dehydrogenase 1/IDH1 Antibody

Isocitrate Dehydrogenase 1/IDH1 Antibody

Isocitrate Dehydrogenase 1/IDH1 Antibody

Isocitrate Dehydrogenase 1/IDH1 Antibody

Isocitrate Dehydrogenase 1/IDH1 Antibody

Isocitrate Dehydrogenase 1/IDH1 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (6)

Reviews

Isocitrate Dehydrogenase 1/IDH1 Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map