Anti-IDH1 R132H Point Mutation specific Antibody (Clone: H09) - prediluted ready-to use DIA-H09-L from dianova GmbH

Product Specs
ItemAnti-IDH1 R132H Point Mutation specific Antibody (Clone: H09) - prediluted ready-to use
Companydianova GmbH
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberDIA-H09-L
Quantity8 ml
ApplicationsImmunohistochemistry, Immunohistochemistry - fixed
Concentrationprediluted, ready to use (RTU)
Conjugate/TagUnconjugated
Purityantibody purified from culture supernatant
ReactivityHuman
TargetIDH1 R132H
IsotypeIgG2a
CloneH09
HostMouse
Antibody TypePrimary Antibody
ImmunogenSynthetic peptide, amino acid sequence CKPIIIGHHAYGD
NCBI Full Gene Nameisocitrate dehydrogenase (NADP(+)) 1, cytosolic
NCBI Gene AliasesIDPC, IDP, HEL-S-26, PICD, IDH, HEL-216, IDCD
ClonalityMonoclonal
Research AreaNeurobiology, Tumormarker/-biologie, Immunohistochemistry
Formatliquid; in PBS with 2% BSA, 0.05% NaN3, pH 7.4
ModificationsR132H

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dianova GmbH

Warburgstr. 45

20354 Hamburg

Germany

Phone: +49 (0) 40 / 45 0 67 - 0
+49 (0) 40 / 45 0 67 - 490

Email: order@dianova.de

Company Profile

Website: http://www.dianova.com

(1) Biomarkers in Adult-Type Diffuse Gliomas: Elevated Levels of Circulating Vesicular Heat Shock Protein 70 Serve as a Biomarker in Grade 4 Glioblastoma and Increase NK Cell Frequencies in Grade 3 GliomaBiomedicinesDecember 7, 2023Philipp Lennartz, Dennis Thölke, Ali Bashiri Dezfouli, Mathias Pilz, Dominik Lobinger, Verena Messner, Hannah Zanth, Karen Ainslie, Morteza Hasanzadeh Kafshgari, Gerhard Rammes, et al.by the guidelines. Sections with a high tumor burden were stained with the prediluted IDH1 antibody (DIA-H09-L RTU, Dianova, Hamburg, Germany) using the automated Ventana Benchmark XT stainer. A granular cytosolic

(2) The clinical and molecular characteristics of progressive hypothalamic/optic pathway pilocytic astrocytomaNeuro-OncologyApril 6, 2023Xiaoyu Li, Daniel C Moreira, Asim K Bag, Ibrahim Qaddoumi, Sahaja Acharya, Jason Chiang(Sigma, #HPA001906, diluted 1:600), BRAF V600E (Ventana, #790-4855, pre-diluted), IDH1 R132H (Dianova, #DIA H09L, clone R132H, diluted 1:50), TBX3 (Abcam, #ab99302, diluted 1:100, positive control: Placental trophoblasts,

(3) Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational statusCell Reports MedicineJanuary 17, 2023Jakob Maximilian Bader, Nikolaus Deigendesch, Martin Misch, Matthias Mann, Arend Koch, Felix MeissnerT6567 styroldivinylbenzol-reversed phase sulfonate (SDB-RPS),Empore 3M,Cat# 13427427 IDH1 R132H antibody,"DIANOVA, clone H09",Cat# DIA-H09-L Polymerase for IDH1 and IDH2 pyrosequencing,"HotStarTag DNA Polymerase, Qiagen",Cat# 203205 ,, Critical

(4) Congenital tumors of the central nervous system: an institutional review of 64 cases with emphasis on tumors with unique histologic and molecular characteristicsBrain PathologyJanuary 1, 2021Angela N. Viaene, Cunfeng Pu, Arie Perry, Marilyn M. Li, Minjie Luo, Mariarita Santi1:100), neurofilament (Thermo Scientific, QL215385, 1:400), EMA (Dako, E29, 1:200), IDH1‐R132H (Dianova, DIA‐H09‐L), ATRX (Sigma, HPA001906, 1:100), H3K27M (Sigma, SAB5600095, 1:1000), GAB1 (Santa Cruz Biotechnology,

(5) MRI Radiomic Features to Predict IDH1 Mutation Status in Gliomas: A Machine Learning Approach using Gradient Tree BoostingInternational Journal of Molecular SciencesOctober 27, 2020Yu Sakai, Chen Yang, Shingo Kihira, Nadejda Tsankova, Fahad Khan, Adilia Hormigo, Albert Lai, Timothy Cloughesy, Kambiz Naelmonoclonal anti-mIDH1 antibody, purified from culture supernatant in PBS (2% BSA, 0.05% NaN3, pH 7.4, DIA-H09L; Dianova, Hamburg, Germany), which has specificity for human IDH1 R132H point mutation. The high frequency

(6) Molecular diagnostic testing of diffuse gliomas in the real-life setting: A practical approachClinical NeuropathologyJuly 1, 2018MichaÅ BieÅkowski, Adelheid Wöhrer, Patrizia Moser, Melitta Kitzwögerer, Gerda Ricken, Thomas Ströbel, Johannes A. Hainfellnerchromogen. IDH1 immunostaining was performed manually in a humidified chamber. Primary antibody IDH1R132H (#DIA H09L, clone H09, Dianova, Hamburg, Germany) was used at a dilution of 1 : 30 for 60 minutes at room temperature.

(7) Overexpression of isocitrate dehydrogenase-1R132H enhances the proliferation of A172 glioma cells via aerobic glycolysisMolecular Medicine ReportsMay 1, 2015QUANMIN NIE et al.

(8) Proximity ligation assay evaluates IDH1R132H presentation in gliomasThe Journal of clinical investigationFebruary 1, 2015Bunse L, Schumacher T, Sahm F, Pusch S, Oezen I, Rauschenbach K, Gonzalez M, Solecki G, Osswald M, Capper D, et al.

(9) ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastomaActa neuropathologicaJanuary 1, 2015David E Reuss, Felix Sahm, Daniel Schrimpf, Benedikt Wiestler, David Capper, Christian Koelsche, Leonille Schweizer, Andrey Korshunov, David T W Jones, Volker Hovestadt, Michel Mittelbronn, Jens Schittenhelm, Christel Herold-Mende, Andreas Unterberg, Michael Platten, Michael Weller, Wolfgang Wick, Stefan M Pfister, Andreas von Deimling

(10) A vaccine targeting mutant IDH1 induces antitumour immunityNatureAugust 21, 2014Theresa Schumacher, Lukas Bunse, Stefan Pusch, Felix Sahm, Benedikt Wiestler, Jasmin Quandt, Oliver Menn, Matthias Osswald, Iris Oezen, Martina Ott, Melanie Keil, Jörg Balß, Katharina Rauschenbach, Agnieszka K Grabowska, Isabel Vogler, Jan Diekmann, Nico Trautwein, Stefan B Eichmüller, Jürgen Okun, Stefan Stevanovic, Angelika B Riemer, Ugur Sahin, Manuel A Friese, Philipp Beckhove, Andreas von Deimling, Wolfgang Wick, Michael Platten

(11) Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH-Mutant GliomasClinical Cancer ResearchJune 1, 2014Hiroaki Wakimoto et al.

(12) Spontaneous in vitro senescence of glioma cells confirmed by an antibody against IDH1R132HAnticancer researchJune 1, 2014Stoczynska-Fidelus E, Och W, Rieske P, Bienkowski M, Banaszczyk M, Winiecka-Klimek M, Zieba J, Janik K, Rosiak K, Treda C, et al.

(13) Can diffusion tensor imaging noninvasively detect IDH1 gene mutations in astrogliomas? A retrospective study of 112 casesAJNR. American journal of neuroradiologyMay 1, 2014W L Tan, W Y Huang, B Yin, J Xiong, J S Wu, D Y Geng

(14) Two cases of multinodular and vacuolating neuronal tumourActa neuropathologica communicationsJanuary 20, 2014Bodi I, Curran O, Selway R, Elwes R, Burrone J, Laxton R, Al-Sarraj S, Honavar M.(cr3/43),1:300,H2(20),Dako,M0775 HuC/HuD,1:160,H1 (30),Molecular probes,A-21271 IDH1,1:50,H1(20),Dianova,DIA H09 L Ki67,1:100,H2(20),Dako,M7240 Nestin,1:200,H2(20),Santa Cruz biotech,sc-23927 Neu N,1:2000,H1(20),Chemicon,MAB377 NF

(15) Comparative study of IDH1 mutations in gliomas by immunohistochemistry and DNA sequencingNeuro-oncologyJune 1, 2013Shipra Agarwal, Mehar Chand Sharma, Prerana Jha, Pankaj Pathak, Vaishali Suri, Chitra Sarkar, Kunzang Chosdol, Ashish Suri, Shashank Sharad Kale, Ashok Kumar Mahapatra, Pankaj Jha

(16) Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KGActa neuropathologica communicationsMay 29, 2013Navis AC, Niclou SP, Fack F, Stieber D, van Lith S, Verrijp K, Wright A, Stauber J, Tops B, Otte-Holler I, et al.

(17) Diagnostic implications of IDH1-R132H and OLIG2 expression patterns in rare and challenging glioblastoma variantsModern pathology : an official journal of the United States and Canadian Academy of Pathology, IncMarch 1, 2013Nancy M Joseph, Joanna Phillips, Sonika Dahiya, Michelle M Felicella, Tarik Tihan, Daniel J Brat, Arie Perry

(18) Disruption of Wild-Type IDH1 Suppresses D-2-Hydroxyglutarate Production in IDH1-Mutated GliomasCancer ResearchJanuary 15, 2013Genglin Jin et al.

(19) Isocitrate dehydrogenase 1R132H mutation in microglia/macrophages in gliomas: indication of a significant role of microglia/macrophages in glial tumorigenesisCancer biology & therapyAugust 1, 2012Ping-Pin Zheng, Marcel van der Weiden, Peter J van der Spek, Arnaud J P E Vincent, Johan M Kros

(20) Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric gliomaAnnals of diagnostic pathologyAugust 1, 2012Aditya Raghunathan, Adriana Olar, Hannes Vogel, John R Parker, Susan C Coventry, Robert Debski, Constance T Albarracin, Kenneth D Aldape, Daniel P Cahill, Suzanne Z Powell, Gregory N Fuller

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Anti-IDH1 R132H Point Mutation specific Antibody (Clone: H09) - prediluted ready-to use from dianova GmbH

dianova GmbH

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Anti-IDH1 R132H Point Mutation specific Antibody (Clone: H09) - prediluted ready-to use from dianova GmbH

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