Anti-MAPK activated protein kinase 2 antibodies are used for the immunodetection of the protein encoded by the MAPKAPK2 gene. In humans, the canonical protein has a reported length of 400 amino acid residues and a mass of 45.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in all tissues examined. A member of the CAMK Ser/Thr protein kinase protein family, it is known to be involved with DNA damage pathways and inflammatory response pathways. Post-translational modifications have been described, including sumoylation and phosphorylation. Other names for this target antigen include MK2, MAP kinase-activated protein kinase 2, MAPKAP kinase 2, mitogen-activated protein kinase-activated protein kinase 2, and MK-2. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.