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  • How to Select the Best siRNA Transfection Reagent

    Choosing an siRNA Transfection Reagent

    Thursday, May 16, 2013
    There are myriad ways to introduce siRNA into the cell, from encoding it in plasmids or viruses (generally as a longer RNA that is then processed by ... read more
  • Microplate Readers: Many Options for Multiple Applications

    Plate Readers Continue to Evolve

    Tuesday, May 14, 2013
    Some microtiter plate readers are dedicated to specific functions, whereas more sophisticated instruments handle multiple tasks. Some read only ... read more
  • Forego the Law of Averages with Single Cell Analysis

    Multiple Approaches to Single Cell Analysis

    Thursday, May 09, 2013
    Single cell analysis is a research area that is growing exponentially, having begun with more sensitive molecular biology tools. We have just seen the... read more
  • Differential Expression Analysis of RNA-Seq Data

    RNA-Seq and the Transcriptome

    Tuesday, May 07, 2013
    RNA-Seq builds on next-generation DNA sequencing (NGS), taking as its input RNA that has been reverse-transcribed into cDNA and (usually) PCR-... read more
  • Tools to Optimize Cell Culture Conditions

    Cell-Line Optimization Comes of Age

    Thursday, May 02, 2013
    For well-studied cell lines, culture conditions are generally well established, and lines obtained from cell banks usually come with protocols for ... read more
  • Picking Apart PAGE: An Overview of Protein Gel Electrophoresis

    Protein Separation via PAGE for Multiple Applications

    Tuesday, April 30, 2013
    An overview of protein gel electrophoresis prior to Western blotting, mass spec, and other applications. read more
  • Whole Genome Sequencing Technologies Enhance Speed and Throughput

    Whole Genome Sequencing’s Speedy Pace

    Thursday, April 25, 2013
    Whole-genome sequencing (WGS) can sequence an entire genome at once, and it is advancing quickly enough to sequence a whole genome in about 24 hours. ... read more
  • Multiple Options for Accurate Cell Counts

    An Overview of Cell Counter Options

    Wednesday, April 24, 2013
    If you work with eukaryotic cells in culture, it’s a sure bet you’ll need to count them, at least occasionally. You need to know how many cells you ... read more
  • Biomarker Analysis: The Intersection of Research and Healing

    Biomarker Analysis

    Tuesday, April 23, 2013
    The very nature of biomarkers can affect how they [perform] and how they should be analyzed, yet there are wide variations in biomarker types, ... read more
  • Choosing a Cell Isolation Kit Comes Down to Method and Marker

    Buying Tips for Cell Isolation Kits

    Friday, April 19, 2013
    Isolation of a genetically homogeneous population of cells is a key step in many cell-based, downstream applications, including gene characterization ... read more
  • Mighty Mice Save the Day: Murine Genetics Reveals Answers to Human Problems

    Mouse Models of Human Disease

    Thursday, April 18, 2013
    The phenomenon means that researchers can genetically induce human diseases, like cancer, in mice to understand the causes or to test novel therapies.... read more
  • Molecular Diagnostics: Molecules of Evidence Advance Diagnostic and Treatment Capabilities

    Molecular Diagnostics

    Wednesday, April 17, 2013
    Molecular diagnostic tests are enabling physicians to pinpoint killers: cancer, Alzheimer’s Disease, cardiovascular disease, bacterial and viral ... read more
  • Real-time PCR: Multiple Options for Nucleic Acid Quantification

    The Latest in qPCR Technologies

    Tuesday, April 16, 2013
    qPCR is a fluorescence-based, quantitative assay. As the reaction runs, its fluorescence intensity changes. A qPCR instrument monitors that ... read more
  • The Cytogenetics Toolbox: Techniques to Study DNA from the Single Nucleotide to the Chromosomal Level

    The Cytogenetics Toolbox

    Thursday, April 11, 2013
    As cells grow and divide, their genetic material acquires changes. Sometimes those are single-base changes, and othertimes, those changes occur on a ... read more
  • Techniques for Reprogramming Stem Cells

    Techniques for Reprogramming Stem Cells

    Tuesday, April 09, 2013
    Even more astonishing than our ability to induce mature adult cells to revert to a pluripotent state – in which they could hypothetically become any ... read more
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