Anti-IKBE antibodies are used in antigen-specific immunodetection in biological samples. The target IKBE is a known alias name of the protein NFKB inhibitor epsilon, encoded by the NFKBIE gene in humans. This 500-amino acid residue protein is reported to inhibit NF-kappa-B by complexing with and trapping it in the cytoplasm. It is localized to the cytoplasm of the cell and features phosphorylated post-translational modifications. In terms of tissue expression, it is reported to be highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Other synonyms for IKBE include NF-kappa-B inhibitor epsilon and I-kappa-B-epsilon.