Anti-MHC Class I antibodies are available from several suppliers for applications in immunodetection, such as ELISA, Western blot, immunohistochemistry, and more. Major histocompatibility complex (MHC) class I molecules are heterodimeric proteins composed of combinations of two polypeptides: beta-2 microglobulin (encoded by the B2M gene) and alpha microglobulin (encoded by the HLA family of genes). HLA gene isotypes include HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, and HLA-G. MHC Class I proteins are expressed on the cell surface and function by presenting antigenic peptide fragments to cytotoxic T cells. Visit the antibody supplier page for more information, including isotype or epitope specificity.