Anti-CD69 antibodies are used in the immunodetection of the protein CD69 molecule. In humans, the canonical protein has a reported length of 199 amino acid residues and a mass of 22.6 kDa. Its subcellular localization is in the membrane. It is noted to be expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. CD69 is known to be involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. Post-translational modifications have been described, including phosphorylation and glycosylation. The CD69 marker can be used to identify CD4+ Resident Memory T Cells, CD8+ Resident Memory T Cells, and CD4+ ?ß Memory T Cells.* Synonyms for this target antigen include BL-AC/P26, CLEC2C, EA1, GP32/28, MLR-3, and AIM. CD69 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4