Electron Microscopy Sample Preparation

Electron Microscopy Sample Preparation Electron Microscopy Sample Preparation instruments are specialized tools for preparing samples for examination under an electron microscope. These include a variety of unique instruments that help ensure that samples are adequately prepared to provide clear and detailed images. Sputter Coaters are used to deposit a thin layer of metal onto a sample, enhancing the sample's conductivity and contrast. High-Pressure Freezers can rapidly freeze samples, preserving the structure and composition of their natural state for accurate imaging. Ultramicrotomes function by cutting ultra-thin sections of a sample, a necessary preparation for transmission electron microscopy (TEM). Cryo preparation and transfer systems prepare samples while maintaining their phsyical integrity under cryogenic conditions. Consult with the manufacturer for more detailed information, including instrument specifications and usage recommendations.

Electron Microscopy Sample Preparation

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EM AC20 Automatic contrasting instrument
Leica Microsystems
  • Description:
    The EM AC20 automatic contrasting system for ultrathin sections ensures minimum user contact with reagents and reduced reagent consumption.

    Usage of a ...
  • Applications:
    Automated staining and contrasting for TEM sample preparation
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Citations:
(159)
EM ACE200 Vacuum Coater
Leica Microsystems
  • Description:
    Desk-top coater for homogeneous coatings of conductive metal or carbon for electron microscopy. Fully automated instrument.

    Options include:
    • Carbon thread ...
  • Applications:
    Sputter and carbon coating of samples for SEM and TEM imaging
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Citations:
(805)
Figures:
(1)
EM ACE600 Sputter Coater
Leica Microsystems
  • Description:
    The EM ACE600 sputter coater is a versatile high vacuum film deposition instrument for your FE-SEM and TEM applications.
    • Enhance contrast by a fine-grained ...
  • Applications:
    High-resolution sputter and carbon coating for SEM, TEM, and cryo-SEM sample preparation
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Citations:
(>1k)
Figures:
(3)
EM ACE900 Freeze Fracture System
Leica Microsystems
  • Description:
    High-end system for freeze fracture applications. High vacuum, a 3-axis movable microtome, and low angle e-beam coating with rotation ensure the best results ...
  • Applications:
    TEM, SEM
Citations:
(48)
EM AFS2 Freeze Substitution and Low Temperature Embedding System for Light and Electron Microscopy
Leica Microsystems
  • Description:
    The EM AFS2 performs freeze substitution and progressive lowering of temperature (PLT) techniques and allows low temperature embedding and polymerization of ...
  • Applications:
    Low-temperature embedding and polymerization of resins
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Citations:
(396)
Figures:
(1)
EM GP2 Automatic Plunge Freezer
Leica Microsystems
  • Description:
    The EM GP2 plunge freezes fluid or extremely thin samples spread on an electron microscopy grid into liquid ethane after removing excess fluid by automatic ...
  • Applications:
    Vitrification of biological samples for cryo-electron microscopy preparation
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Citations:
(691)
Figures:
(1)
EM ICE High Pressure Freezer
Leica Microsystems
  • Description:
    High pressure system for freezing aqueous samples delivers optimal sample preservation. Offers the highest flexibility to meet multiple application demands.
  • Applications:
    Cryo-fixation of biological samples for electron microscopy ultrastructure preservation
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Citations:
(263)
Figures:
(3)
EM ICE Nano
Leica Microsystems
  • Description:
    High pressure system for freezing aqueous samples delivers optimal sample preservation. Equip for fast sample transfers for optimal sample fixation.
  • Applications:
    Cell biology; EM sample preparation
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Citations:
(209)
Figures:
(1)
EM RAPID Specimen Trimming Device
Leica Microsystems
  • Description:
    The EM RAPID milling system for pharmaceutical research enables sample preparation for analysis of active ingredient distribution on solid-dose pharmaceuticals....
  • Applications:
    High-speed milling system for TEM, SEM, LM and pharmaceutical milling of pills
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Citations:
(12)
EM TP Automated Tissue Processor
Leica Microsystems
  • Description:
    The innovative EM TP is the first tissue processor designed for EM and LM resin processing that features a heating/cooling system with pre-heat and pre-cool ...
  • Applications:
    Automated dehydration, infiltration, and embedding for electron microscopy sample preparation
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Citations:
(133)
EM TXP Target Surfacing System
Leica Microsystems
  • Description:
    The EM TXP is a target preparation device for milling, sawing, grinding, and polishing samples prior to examination by SEM, TEM, and LM techniques.

    An ...
  • Applications:
    Milling, sawing, grinding, and polishing samples prior to examination by SEM, TEM, and LM
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Citations:
(51)
EM VCT500 Vacuum Cryo Transfer System
Leica Microsystems
  • Description:
    Versatile vacuum cryo transfer system for contamination-free transfer of specimens between different preparation and analysis instruments.

    With the EM VCT500 ...
  • Applications:
    Cryo-transfer of vitrified samples for cryo-electron microscopy imaging
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Citations:
(68)
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Leica Microsystems
EM ACE200
2
1 Figure from 805 Publications
Leica Microsystems
EM ACE600
1
3 Figures from 1583 Publications
Leica Microsystems
EM AFS2
1
1 Figure from 396 Publications
Leica Microsystems
EM GP2
2
1 Figure from 691 Publications
Leica Microsystems
EM ICE
1
3 Figures from 263 Publications
Leica Microsystems
EM ICE
3
1 Figure from 209 Publications
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