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Automated DNA/RNA Purification Sample Preparation Workstations
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
Be the first to write a review!
Citations:
(881)
Figures:
(1)
Supplier Page
Supplier Page from
Promega for
Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV Lamp
Avg. lifetime approximately 6,000 hrs
Molecular Weight
~85kDa
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (881)
(161)
Discovery of glycerol phosphate and an immunogenic glycan motif in rhamnose-rich polysaccharides of Streptococcus uberis
Vet Res
July 7, 2025
Yao Shi, Göran Widmalm, Natalia Korotkova, Adrian Molenaar, Mark A. Holmes, Scott McDougall, Jetta J. E. Bijlsma, Nina M. van Sorge, Lindert Benedictus
120 rpm.
Whole-genome sequencing
and assembly Genomic DNA of S. uberis 233 was isolated using the
Maxwell® RSC Instrument
(
Promega
) after overnight growth in THY broth. DNA was quantified by
Qubit Fluorometer
(
Invitrogen
).
(162)
Efficient cell-free translation from diverse human cell types
Journal of Biological Chemistry
July 1, 2025
Jana Ziegelmüller, Nikolaos Kouvelas, Nino Schwaller, Priyanka Thambythurai, Alexander M. Hofer, Oliver Mühlemann, Evangelos D. Karousis
extraction RNA extraction for
RT-qPCR
analysis was carried out using the
Maxwell RSC Instrument
(
Promega
, Cat#
AS4500
) and the
Maxwell RSC simplyRNA Cells Kit
(
Promega
, Cat#
AS1390
), following the manufacturer’s protocol.
(163)
Comparative transcriptomics of salinomycin molecular toxicity in chicken and turkey
Sci Rep
July 1, 2025
İlksen Berfin Ekinci, Anna Sławińska, Kacper Żukowski, Małgorzata Olejnik
summarized in Fig. 1. RNA isolation The total RNA was isolated from the liver and heart samples using the
Maxwell® RSC instrument
(
Promega
, USA). The tissue size was 100 mg, and the extraction was performed with
Maxwell® RSC simplyRNA Tissue Kit
(164)
Examination of the enrichment of neuronal extracellular vesicles from cell conditioned media and human plasma using an anti-NCAM immunocapture bead approach
BMC Methods
July 1, 2025
Mary E. W. Collier, Natalie Allcock, Nicolas Sylvius, Jordan Cassidy, Flaviano Giorgini
was isolated from the EV lysates using the Maxwell RSC
miRNA
from plasma and serum kit (Promega) on a
Maxwell RSC instrument
(
Promega
) according to the manufacturer’s instructions and eluted in 40 µl of nuclease free water. RNA
(165)
Comparative Evaluation of the Serological Methods and the Molecular Genetics Techniques for the Diagnosis of Encephalitozoon cuniculi in Rabbits (Oryctolagus cuniculus)
Microorganisms
June 25, 2025
Anca-Alexandra Doboși, Anamaria Ioana Paștiu, Sanda Andrei, Dana Liana Pusta
samples, where the enzymatic digestion of the samples was performed with proteinase K at 56 °C. The
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA) for automatic extractions was required for this process and the final products
(166)
Identification of diagnostic DNA methylation markers in the blood of Japanese Alzheimer's disease patients using methylation capture sequencing
Clin Epigenetics
June 20, 2025
Risa Mitsumori, Kayoko Sawamura, Kimi Yamakoshi, Akinori Nakamura, Yutaka Arahata, Shumpei Niida, Daichi Shigemizu, Kouichi Ozaki, Nobuyoshi Shimoda
obtained from the NCGG biobank. Preparation of gDNA gDNA was extracted from peripheral blood using a
Maxwell RSC Instrument
(
Promega
, USA) with the
Maxwell RSC Buffy Coat DNA Kit
(
Promega
, USA). The quantity of gDNA was measured
(167)
Sustainable water reuse in food production: risks of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and antimicrobial resistance gene release from tertiary-treated reclaimed water
Frontiers in Microbiology
June 19, 2025
Pilar Truchado, Márcia Oliveira, Rebeca Cordero-García, Manuel Abellán Soler, Amador Rancaño, Francisca García, Avelino Álvarez-Ordóñez, Ana Allende
genomic DNA extraction. Genomic DNA extraction from wastewater concentrates was performed using the
Maxwell® RSC Instrument
(
Promega
) and the Maxwell RSC Pure Food GMO and Authentication Kit (Promega), following the Maxwell
(168)
Marked reduction of SARS-CoV-2 infection and improved recovery following supplementation with a probiotic mix of four strains and two strains of Bifidobacterium breve in hamsters
Applied and Environmental Microbiology
June 18, 2025
Edgar Torres-Maravilla, Marine Wasniewski, Aurélie Wauquier, Alexandre Servat, Evelyne Picard-Meyer, Elodie Monchatre-Leroy, Sandrine Auger, Sophie Holowacz, Franck Boué, Philippe Langella,
et al.
DNA was extracted from 100 mg of fecal sample using the
Maxwell RSC Fecal Microbiome DNA Kit
on the
Maxwell RSC Instrument
according to the provided user guidelines (
Promega
). The concentration and quality of extracted DNA
(169)
Pollen parent affects rutin content of seeds of buckwheat (
Fagopyrum esculentum
)
Breeding Science
June 18, 2025
Shiori Otsuka, Takashi Hara, Koji Ishiguro, Kenichi Matsushima, Yasuo Yasui, Katsuhiro Matsui
with a mortar and pestle. Total RNA was extracted from the seeds with a
Maxwell RSC Plant RNA Kit
in a
Maxwell RSC Instrument
(
Promega
) according to the manufacturer’s protocol. A
Next Generation Sequencing
library was constructed
(170)
Targeting inflammatory macrophages with hyaluronan tetrasaccharide: effects on fibroblast collagen degradation and synthesis
Front Immunol
June 5, 2025
Eiko Uno, Florence Kim, Mihoko Yoshino, Yasunari Sato, Masao Hashimoto, Kenji Watanabe, Yoichi Mizukami, Jun Muto
Cambridge, UK). 2.7 Real-time
qPCR
analysis Total RNA was extracted from
macrophages
and NHDF with the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA) following the manufacturer’s guidelines. The complementary DNA (cDNA) library
(171)
Visualizing fatigue mechanisms in non-communicable diseases: an integrative approach with multi-omics and machine learning
BMC Med Inform Decis Mak
June 3, 2025
Yusuke Kobayashi, Naoki Fujiwara, Yuki Murakami, Shoichi Ishida, Sho Kinguchi, Tatsuya Haze, Kengo Azushima, Akira Fujiwara, Hiromichi Wakui, Masayoshi Sakakura,
et al.
gene
sequencing
to characterize microbial communities. Extraction of DNA was performed using a
Promega
Maxwell RSC Instrument
(Promega Corporation, Madison, WI, USA), and the V3–V4 regions of the 16S rRNA gene were amplified using
(172)
Wastewater surveillance of SARS-CoV-2 from aircraft to citywide monitoring
Nat Commun
June 2, 2025
Mariel Perez-Zabaleta, Carlo Berg, Neus Latorre-Margalef, Isaac Owusu-Agyeman, Ayda Kiyar, Helene Botnen, Caroline Schönning, Luisa W. Hugerth, Zeynep Cetecioglu
loaded into a cartridge provided by the kit. Afterwards, total nucleic acid (TNA) was extracted using
Maxwell RSC Instrument
(
Promega
Biotech AB, Sweden) and Maxwell RSC Pure Food GMO programme was selected. The elution volume
(173)
Low-grade oncocytic tumor of the kidney-a clinical, pathological, and next generation sequencing-based study of 20 tumors
Pathol Oncol Res
June 2, 2025
Alex Jenei, Boglárka Pósfai, Borbála Dénes, Áron Somorácz, Gertrud Forika, Attila Fintha, Zsófia Mészáros, Noémi Kránitz, Tamás Micsik, Kornélia Veronika Eizler,
et al.
sequencing
was carried out.
Nucleic acid isolation
was performed using Maxwell RSC DNA/RNA FFPE Kit on
Maxwell RSC Instrument
(
Promega
) according to the manufacturer’s instruction. DNA and RNA concentrations were measured using
(174)
Cracking rare disorders: a new minimally invasive RNA-seq protocol
NPJ Genom Med
May 28, 2025
Laurenz De Cock, Erika D'haenens, Lies Vantomme, Lynn Backers, Aude Beyens, Kathleen Bm Claes, Griet De Clercq, Robin de Putter, Candy Kumps, Nika Schuermans,
et al.
kb (as described earlier44). RNA extraction RNA was extracted using the
Maxwell® RSC instrument
(
AS4500
,
Promega
). Depending from which tissue RNA was isolated a different extraction kit was used: (1) PBMCs,
(175)
A multi-omics integration approach relying on circulating factors does not discern subtypes of childhood type 1 diabetes
Commun Med (Lond)
May 27, 2025
Valentina Codazzi, Nicola Baldoni, Giulia M. Scotti, Anna Giovenzana, Andrea Rigamonti, Giulio Frontino, Eugenia Bezzecchi, Camillo Bechi Genzano, Alessandra Mandelli, Debora Carnovale,
et al.
from whole blood was conducted on a subset of 90 subjects using the
Maxwell® RSC Blood DNA Kit
and the
Maxwell® RSC Instrument
from
Promega
. For each participant, the
Type 1 Diabetes
Genetic
Risk Score
2 (T1D GRS-2) was calculated.
(176)
The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features
Molecular Oncology
May 26, 2025
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany
next‐generation sequencing
Genomic DNA was extracted using the
Maxwell® RSC DNA FFPE Kit
and the Maxwell® RSC Blood Kit, and the
Maxwell® RSC instrument
(
Promega
, Madison, WI, USA) according to the manufacturer's instructions. Targeted multigen mutation
(177)
Microevolution and genomic epidemiology of the diphtheria-causing zoonotic pathogen Corynebacterium ulcerans
Nat Commun
May 24, 2025
Chiara Crestani, Virginie Passet, Martin Rethoret-Pasty, Nora Zidane, Sylvie Brémont, Edgar Badell, Alexis Criscuolo, Sylvain Brisse
protocol described by the manufacturer38. DNA extraction for Oxford Nanopore
sequencing
was performed on a
Maxwell RSC Instrument
(
Promega
, Madison, USA) with the
Maxwell RSC Blood DNA Kit
(
Promega
, Madison, Wisconsin, USA) following
(178)
Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activity
Angiogenesis
May 23, 2025
Sarah E. J. Chambers, Jasenka Guduric-Fuchs, Edoardo Pedrini, Pietro M. Bertelli, Chutima Charoensuk, Elisa Peixoto, Varun Pathak, Hamza I. Alhamdan, Ruoxiao Xie, Anna Krasnodembskaya,
et al.
barrier. Real-time qRT-
qPCR
Total RNA was isolated using the
Maxwell RSC simplyRNA Cells Kit
(
Promega
) and a
Maxwell RSC instrument
(
Promega
) following the manufacturer’s instructions. RNA quantity and purity were assessed using the
(179)
TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysis
Front Immunol
May 19, 2025
Miguel Chirivi, Ursula Abou-Rjeileh, Madison Myers, Jair Parales-Giron, Lynn Worden, Adam L. Lock, G. Andres Contreras
genomic DNA, 5 µL of DNase I (Promega) was added. Automated
extraction of RNA
was carried out using the
Maxwell® RSC instrument
(
Promega
Corp.). RNA was flash-frozen in LN2, stored at -80°C, and the concentration and integrity of
(180)
Presence of Potentially Infectious Human Enteric Viruses and Antibiotic Resistance Genes in Mussels from the Campania Region, Italy: Implications for Consumer's Safety
Food Environ Virol
May 15, 2025
Iolanda Venuti, Enric Cuevas-Ferrando, Irene Falcó, Inés Girón-Guzmán, Marina Ceruso, Tiziana Pepe, Gloria Sánchez
– 80 °C (Fig. 2). Nucleic acid extraction from
mussel
concentrates (300 μL) was performed using the
Maxwell® RSC Instrument
(
Promega
, Spain) with the Maxwell RSC Pure Food GMO and authentication kit (Promega), utilizing the
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Maxwell RSC Instrument from Promega
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