Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(161) The Impact of Tartrazine on DNA Methylation, Histone Deacetylation, and Genomic Stability in Human Cell LinesNutrientsMarch 6, 2025Afshin Zand, John M. Macharia, Istvan Szabó, Gellért Gerencsér, Ádám Molnár, Bence L. Raposa, Timea Varjasmanufacturer’s instructions, total RNA was extracted using a semiauto-mated procedure made possible by the Maxwell® RSC Instrument (Promega, Fitchburg, WI, USA) and a Maxwell® RSC RNA FFPE Kit (AS1440, Promega, Fitchburg, WI, USA).

(162) A genome-wide association study identifies a novel East Asian-specific locus for dementia with Lewy bodies in Japanese subjectsMol MedMarch 6, 2025Risa Mitsumori, Yuya Asanomi, Takashi Morizono, Daichi Shigemizu, Shumpei Niida, Kouichi OzakiHelsinki. Genomic DNA was extracted from peripheral blood leukocytes by standard protocols using a Maxwell RSC Instrument and a Maxwell RSC Buffy Coat DNA Kit (Promega, Madison, WI, USA). Genotyping and quality control for

(163) Rhodococcus spp. interacts with human norovirus in clinical samples and impairs its replication on human intestinal enteroidsGut MicrobesMarch 3, 2025Cristina Santiso-Bellón, Walter Randazzo, Noelia Carmona-Vicente, Nazaret Peña-Gil, Roberto Cárcamo-Calvo, Sergi Lopez-Navarro, Noemi Navarro-Lleó, Maria J. Yebra, Vicente Monedero, Javier Buesa, et al.replication. Quantification of GII.4 Sydney 2012 NoV replication in HIE Viral RNA was extracted using the Maxwell® RSC Instrument (Promega) according to the manufacturer’s instructions. Then, NoV RNA was detected in duplicate by TaqMan

(164) Molecular Profiling of Sinonasal Adenoid Cystic Carcinoma: Canonical and Noncanonical Gene Fusions and MutationAmerican Journal of Surgical PathologyMarch 1, 2025Alena Skálová, Martina Bradová, Abbas Agaimy, Jan Laco, Cécile Badual, Stephan Ihrler, Ivan Damjanov, Niels J. Rupp, Carlos E. Bacchi, Sarina Mueller, et al.Oncology 500 Kit (Illumina, San Diego, CA). RNA was extracted using the Maxwell RSC DNA FFPE Kit and the Maxwell RSC Instrument (Promega, Madison, WI) according to the manufacturer’s instructions and quantified using the Qubit HS

(165) Bi-allelic LAMP3 variants in childhood interstitial lung disease: a surfactant-related diseaseEBioMedicineMarch 1, 2025Louvrier C, Desroziers T, Soreze Y, Delgado Rodriguez M, Thomas L, Nau V, Dastot-Le Moal F, Bernstein JA, Cole FS, Damme M, et al.manufacturer's protocol. RNA from lung biopsy was extracted using the Maxwell RSC simply RNA tissue Kit on a Maxwell RSC instrument (Promega) according to the manufacturer's protocol with an initial stage of manual grinding of lung

(166) Skim Milk Culture of Lactobacillus johnsonii SBT0309 Increases Intestinal Alkaline Phosphatase Activity and Inhibits Lipopolysaccharide-Induced Interleukin-8 Production in Intestinal Epithelial CellsCellsFebruary 28, 2025Michio Kawano, Toshinobu Arai, Toshihide Kabukiice-cold saline, we isolated total RNA from Caco-2 cells using Maxwell RSC simplyRNA Tissue Kits and a Maxwell RSC Instrument (Promega, Madison, WA, USA). Total RNA extracted from five Drosophila pulverized midgut using an RNeasy

(167) Preventive effects of Weissella cibaria CMU on the progression of periodontitis in a rat modelJ Oral MicrobiolFebruary 26, 2025Kyung-Hyo Do, Soyoung Boo, Rayoung You, Sanggu Kim, Soochong Kim, Kwang-Won Seo, Mi-Sun Kang, Wan-Kyu LeeDNA from bacteria was extracted from samples collected through oral swabs with the assistance of a Maxwell RSC Instrument (Promega, Madison, WI, USA) alongside a Maxwell RSC Fecal Microbiome DNA Kit AS1700 (Promega), in accordance

(168) Sinonasal adenoid cystic carcinomas accompanied by seromucinous hamartoma and/or atypical sinonasal glands arising from seromucinous hamartoma: insight into their histogenesisVirchows ArchivFebruary 22, 2025Martina Bradová, Abbas Agaimy, Jan Laco, Petr Martínek, Stanislav Kormunda Ing, Cécile Badoual, Ivan Damjanov, Ilmo Leivo, Carlos E. Bacchi, Eva Comperat, et al.Oncology 500 Kit (Illumina, San Diego, CA). RNA was extracted using the Maxwell RSC DNA FFPE Kit and the Maxwell RSC Instrument (Promega, Madison, WI) according to the manufacturer’s instructions and quantified using the Qubit HS

(169) Comparative Analysis of Transcriptomic and Proteomic Expression between Two Non-Small Cell Lung Cancer SubtypesJournal of Proteome ResearchFebruary 7, 2025Ben Nicholas, Alistair Bailey, Katy J. McCann, Peter Johnson, Tim Elliott, Christian Ottensmeier, Paul Skippnitrogen. Ten to twenty 10 μm cryosections were used for nucleic acid extraction using an automated Maxwell RSC instrument (Promega) and a Maxwell RSC simplyRNA tissue kit according to the manufacturer’s instructions. RNA was

(170) Differential Expression of miR-223-3p and miR-26-5p According to Different Stages of Mastitis in Dairy CowsBiomoleculesFebruary 6, 2025Eleonora Dall'Olio, Fabio De Rensis, Eugenio Martignani, Silvia Miretti, Ugo Ala, Valeria Cavalli, Claudio Cipolat-Gotet, Melania Andrani, Mario Baratta, Roberta SaleriUSA), an automated system for obtaining high-quality total RNA with enhanced miRNA enrichment on a Maxwell® RSC Instrument (Promega, Madison, WI, USA). c-miRNAs from the immune-cell culture mediums were extracted using a protocol

(171) Prognostic Factors, FLT-3 Mutations, and Treatment Outcomes with pediatric inspired protocols in adolescent and young adults (AYA) and adult patients with Acute Lymphoblastic LeukemiaActa HaematologicaJanuary 30, 2025Noa Gross Even Zohar, Uriel Oanunu, Noa Gross Even-Zohar, Shlomzion Aumann, Vladimir Vainstein, Alexander Gural, Moshe E Gatt, Arnon Haran, Boaz Nachmiasred blood cell lysis buffer. Cell pellet was subjected for DNA extraction with Maxwell® RSC Blood DNA Kit using Maxwell® RSC Instrument. Detection of FLT-3-ITD Mutation DNA fragment encompassing exons 11–12 of FLT-3 gene was amplified

(172) MUC2 expression modulates immune infiltration in colorectal cancerFrontiers in ImmunologyJanuary 24, 2025Christophe M. Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad A. Al-Shaibi, Bernice Lo, Jessica Roelands, Davide Bedognetti, et al.(Promega, #AS1390) according to the manufacturer’s recommendations using Maxwell® RSC Instrument (Promega, #AS4500). RNA was recovered with 50 µL of RNase free water and measured with QuantiFluor® RNA System (Promega,

(173) Identification of the clinical and genetic characteristics of gliomas with gene fusions by integrated genomic and transcriptomic analysisEur J Med ResJanuary 23, 2025Guo-Zhong Yi, Hua-Yang Zhang, Tian-Shi Que, Shan-Qiang Qu, Zhi-Yong Li, Song-Tao Qi, Wen-Yan Feng, Guang-Long Huangthe Maxwell RSC Blood DNA Kit (cat# AS1400, Promega, Madison, WI, USA) on a Maxwell RSC system (cat# AS4500, Promega). For formalin-fixed, paraffin-embedded (FFPE) tissue, DNA was extracted using the MagMAX FFPE DNA/RNA Ultra Kit

(174) Impact of Genetic Variants on Pregabalin Pharmacokinetics and SafetyPharmaceuticals (Basel)January 23, 2025Sofía Calleja, Andrea Rodríguez-López, Dolores Ochoa, Sergio Luquero, Marcos Navares-Gómez, Manuel Román, Gina Mejia-Abril, Samuel Martín-Vilchez, Francisco Abad-Santos, Pablo Zubiaurconcentrate was resuspended in 0.9% NaCl to preserve the blood sample. DNA extraction was performed using the Maxwell® RSC Instrument (Promega, Madison, WI, USA). Genotyping was carried out using a QuantStudio 12k Flex real-time PCR System

(175) Transcriptomic analysis reinforces the implication of spatacsin in neuroinflammation and neurodevelopmentSci RepJanuary 18, 2025Liriopé Toupenet Marchesi, Daniel Stockholm, Typhaine Esteves, Marion Leblanc, Nicolas Auger, Julien Branchu, Khalid Hamid El Hachimi, Giovanni StevaninSimplyRNA Tissue - Promega kit). Subsequently, RNA extraction was performed in a Maxwell RSC instrument (AS4500) by transferring the tissue lysates to the first well of each RSC cartridge pre-filled with buffer (Maxwell

(176) Genomic Insights Into Red Squirrels in Scotland Reveal Loss of Heterozygosity Associated With Extreme Founder EffectsEvol ApplJanuary 15, 2025Melissa M. Marr, Emily Humble, Peter W. W. Lurz, Liam A. Wilson, Elspeth Milne, Katie M. Beckmann, Jeffrey Schoenebeck, Uva-Yu-Yan Fung, Andrew C. Kitchener, Kenny Kortland, et al.DNA Extraction and Sequencing DNA was extracted from c. 50 mg of tissue using the automated Promega Maxwell RSC instrument in conjunction with the Maxwell RSC PureFood and GMO Authentication Kit. Double‐stranded, single‐index,

(177) Altered microbiome and metabolome profiling in fearful companion dogs: An exploratory studyPLoS OneJanuary 15, 2025Luigi Sacchettino, Michele Costanzo, Iolanda Veneruso, Valeria D'Argenio, Maria Mayer, Francesco Napolitano, Danila d'Angeloextracted from each collected faecal sample by using the RSC Blood DNA kit and was purified using the Maxwell RSC instrument (both from Promega, Madison, WI, USA). In detail, 100 mg of each sample were treated with 400 μL of

(178) Analysis of Differences in the Classification of Endometrial Cancer Patients in PolandCancers (Basel)January 10, 2025Wiktor Szatkowski, Tomasz Kluz, Małgorzata Cieślak-Steć, Magdalena Śliwińska, Małgorzata Nowak-Jastrząb, Izabela Winkler, Jacek Tomaszewski, Paweł BlecharzDNA isolation:QIAamp DSP DNA FFPE Tissue Kit (Qiagen, Hilden, Germany);Maxwell® RSC DNA FFPE Kit and Maxwell® RSC Instrument (Promega, Madison, WI, USA). 2.4. Molecular Analysis POLE Sequencing Sanger sequencing was conducted

(179) Synthetic GPR84 Agonists in Colorectal Cancer: Effective in THP-1 Cells but Ineffective in BMDMs and MC38 Mouse Tumor ModelsInternational journal of molecular sciencesJanuary 9, 2025Schwarzfischer M, Walker MR, Curcio M, Boshta NM, Marchand A, Soons E, Pöhlmann D, Wawrzyniak M, Morsy Y, Lang S, et al.washed twice with PBS (0.5 mL, pH 7.4). RNA was isolated using a Maxwell RSC simplyRNA Cell kit and the Maxwell RSC instrument (Promega, Madison, WI, USA) according to the manufacturer’s instructions. RNA concentration was quantified,

(180) The integrated stress response drives MET oncogene overexpression in cancersThe EMBO JournalJanuary 7, 2025Marina Cerqua, Marco Foiani, Carla Boccaccio, Paolo M Comoglio, Dogus M Altintasisolated from cells using the Maxwell RSC miRNA Tissue Kit (Catalogue number AS1460, Promega) with the Maxwell RSC Instrument and reverse transcribed using the SuperScript III First-Strand Synthesis System (ThermoFisher Scientific™,

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