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Automated DNA/RNA Purification Sample Preparation Workstations
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
Be the first to write a review!
Citations:
(908)
Figures:
(1)
Supplier Page
Supplier Page from
Promega for
Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV Lamp
Avg. lifetime approximately 6,000 hrs
Molecular Weight
~85kDa
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (908)
(161)
FOXR2 activation is not exclusive of CNS neuroblastoma
Neuro-Oncology
September 8, 2025
Alexa N Siskar, Emily Hanzlik, Maria F Cardenas, Mohammad K Eldomery, Soniya Pinto, Christopher L Tinkle, Qunyu Zhang, Xiaoyu Li, Tong Lin, Sandeep K Dhanda,
et al.
Whole Genome Sequencing
and Analysis Genomic DNA was extracted from snap-frozen
tumor
tissue using an automated
Maxwell RSC Instrument
(
Promega
), as previously described.15,16,26 DNA quality was assessed on a 4200 TapeStation (Agilent).
(162)
Myeloid sarcoma shows a high frequency of mutations activating the MAPK/ERK pathway and association with clonal hematopoiesis
The Journal of Pathology: Clinical Research
September 4, 2025
Dominik Nann, Tim‐Colin Schade, Mathis Overkamp, Lejla Mahmutovic, Eyyub Bag, Stephan Forchhammer, Julia Slotta‐Huspenina, Ludmila Boudova, Karl Sotlar, Leticia Quintanilla‐Martinez,
et al.
5 μm paraffin sections using the
Maxwell® RSC DNA FFPE Kit
, the
Maxwell® RSC RNA FFPE Kit
, and the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA) according to the manufacturer's instructions.
Next‐generation sequencing
(163)
EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder
Movement Disorders
September 1, 2025
Cleo Schwarz, Florian Bartenschlager, Olivia Kershaw, Judith Braun, Julien Guevar, Vidhya Jagannathan, Jörg T. Epplen, Wencke Reineking, Wolfgang Baumgärtner, Kailash P. Bhatia,
et al.
Extraction Genomic DNA was extracted from EDTA blood with either the
Maxwell RSC whole blood DNA kit
on a
Maxwell RSC instrument
(
Promega
, Madison, WI, USA) or by using a QIAamp DNA Mini Kit (Qiagen GmbH, Hilden, Germany) according
(164)
Monitoring SARS‐CoV‐2 Dissemination in Wastewater and Virus Isolation in Cell Cultures: An Integrated Approach for Pathogen Detection and Surveillance
Journal of Cellular and Molecular Medicine
September 1, 2025
Elena Radu, Tudor Emanuel Fertig, Laura Denisa Dragu, Ioana Mădălina Pitică, Marius Surleac, Ana Iulia Neagu, Lavinia Pană, Alexandra Păiş, Lilia Matei, Ionut‐Lucian Antone‐Iordache,
et al.
and run on a FastPrep24 machine for 40 s at 6 m/s. The RNA extraction was performed on Maxwell RSC
AS4500
(
Promega
) device using the Viral RNA/DNA Extraction Kit from WW (Promega). Total viral RNA was eluted
(165)
Evaluating novel and conventional cell‐separation techniques for sexual assault investigations
Journal of Forensic Sciences
September 1, 2025
Janine Schulte, Simon Egger, Sarah Kron, Eva Scheurer, Iris Schulz
manufacturer's protocol [37]. Samples (including cell fractions and reference samples) were extracted on a
Maxwell® RSC Instrument
(
Promega Corporation
, Madison, USA) using the
Maxwell® FSC DNA IQ™ Casework Kit
(
Promega
) [38], with
(166)
Infant Botulism and Carbohydrate Blood Group Antigens: Preliminary Results from a Discordant Twin Study
The Journal of Pediatrics: Clinical Practice
September 1, 2025
Haydee A. Dabritz, Mayuri V. Panditrao, Suchitra Pandey, Nir Dover, Jason R. Barash, Jessica M. Khouri, Jennifer S. Read
FUT2 Gene to Determine Secretor Status Genomic DNA was extracted from 100 μl buffy coats with the
Maxwell RSC instrument
, using the buffy coat kit, according to the manufacturer's protocol (
Promega
), and were eluted into
(167)
A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context
Molecular Biology and Evolution
September 1, 2025
Esra Durmaz Durmaz Mitchell, Envel Kerdaffrec, Paul Schmidt, Thomas Flatt, Sebastian Kittelmann
directions were pooled. Total RNA was extracted using a
Promega
Maxwell RSC simplyRNA Tissue Kit
and
Maxwell RSC Instrument
, following the manufacturer's protocol. TruSeq stranded
mRNA-seq
library preparation and
sequencing
(168)
Vagococcus lutrae Isolation in a Cat with Feline Urological Syndrome in Italy: A Case Report
Microorganisms
August 29, 2025
Daniela Averaimo, Sabrina Vanessa Patrizia Defourny, Alessandra Alessiani, Marco Rulli, Alexandra Chiaverini, Marco Di Domenico, Iolanda Mangone, Cinzia Pompilii, Vanessa Piersanti, Roberta Giancristofaro,
et al.
and vancomycin (1–16 µg/mL). DNA extraction was performed using the
Maxwell® RSC Genomic DNA Kit
on
Maxwell® RSC Instrument
(
Promega
, Milano, Italy), and DNA quantity and quality were evaluated with a
Quantus™ Fluorometer
(
Promega
,
(169)
Sex-related differences in cell-free DNA and neutrophil extracellular traps in patients with hematologic malignancies
Immunol Res
August 26, 2025
Gaia Gnecco, Alessandro Davini, Arianna Valeriano, Patrizia Mancuso, Enrico Derenzini, Giuseppe Lamorte, Daniele Prati, Giovanna Talarico, Francesco Bertolini
(
Maxwell RSC ccfDNA Plasma Kit
,
Promega
, Madison, WI, USA,
AS1840
) on an automatic extractor (Maxwell,
Promega
, Madison, WI, USA,
AS4500
) according to the manufacturer’s instructions and stored at − 20 °C.
Neutrophil
and
lymphocyte counts
(170)
In Vitro Assessment of a Novel Piranha‐Passivated Dental Implant Surface Against Oral Biofilm Formation
Clinical Oral Implants Research
August 25, 2025
Paula Nuevo, Leire Virto, Honorato Ribeiro‐Vidal, Javier Gil, Mariano Sanz
13,000 r.p.m. for 3 min, and DNA was extracted from the pelleted cells using an automated DNA extractor (
Maxwell RSC Instrument
,
Promega
, Madison, USA), along with its corresponding commercial kit (
Maxwell RSC Genomic DNA Kit
,
Promega
,
(171)
Inter-Island Whole-Genome Comparison Reveals Micro-Evolutionary Dynamics of the Red Fox, Stimulated Through Post-Glacial Sea-Level Alterations
Genome Biol Evol
August 21, 2025
Takumi Watanabe, Shin Shinojima Satoh, Toshiaki Shiraishi, Shosei Kubota, Yuji Yamazaki
Whole-Genome Sequencing
Genomic DNA (gDNA) was extracted from each sample using an automatic
nucleic acid purification
device
Maxwell RSC Instrument
(
Promega
Corp., Madison, WI, U.S.A.), following the protocol of the
Maxwell RSC Tissue DNA Kit
. Tissues
(172)
Soma-localized Rab39 inhibits synaptic autophagy by controlling trafficking of Atg9 vesicles
The EMBO Journal
August 21, 2025
Ayse Kilic, Gokhan Ozturan, Dirk Vandekerkhove, Sabine Kuenen, Jef Swerts, Esther Muñoz Pedrazo, Carles Calatayud Aristoy, Abril Escamilla Ayala, Nikky Corthout, Pablo Hernández Varas,
et al.
was extracted from 10 adult
Drosophila
heads (5 males and 5 females, 5 days old) per sample using the
Maxwell RSC Instrument
and Maxwell RSC RNA Kit (
Promega
), according to the manufacturer’s instructions.
First-strand cDNA synthesis
(173)
Adjuvant anti-PD-1 therapy improves melanoma-specific survival in stage IIIC-IV melanoma patients with high tumor mutation burden and BRAF V600 mutation
Front Oncol
August 12, 2025
Julia Forschner, Julia Huynh, Christopher Schroeder, Sorin Armeanu-Ebinger, Olga Seibel-Kelemen, Axel Gschwind, Irina Bonzheim, Thomas K. Eigentler, Teresa Amaral, Stephan Ossowski,
et al.
DNA was isolated from
tumor
FFPE tissue and blood samples using the
Maxwell® RSC DNA FFPE kit
and the
Maxwell® RSC instrument
(
Promega
, Madison, WI, USA) according to the manufacturer’s standard protocols. After isolation, 200
(174)
Detecting actionable mutations from matched plasma-based versus tissue next-generation sequencing in advanced non-small cell lung cancer: a retrospective single centre analysis on site
J Exp Clin Cancer Res
August 6, 2025
Christophe Bontoux, Caroline Lacoux, Jonathan Benzaquen, Jacques Boutros, Guylène Rignol, Elodie Long-Mira, Sandra Lassalle, Maryline Allegra, Doriane Bohly, Mathieu Garcia,
et al.
cytological specimens and surgically resected specimens, using the
Maxwell RSC Instrument
(
Promega
, #
AS4500
) with the
Maxwell RSC FFPE Plus DNA Kit
(#
AS1720
) and
Maxwell RSC RNA FFPE Kit
(#
AS1440
). Extracted
(175)
LMF1 frameshift deletion in Franches-Montagnes horses with hypertriglyceridemia-induced pancreatitis
Sci Rep
August 6, 2025
Michaela Drögemüller, Nathalie Fouché, Michelle Wyler, Corinne Gurtner, Seraina L. Meister, Markus Neuditschko, Vidhya Jagannathan, Vinzenz Gerber, Tosso Leeb
DNA was extracted from EDTA blood using the
Maxwell RSC Whole Blood DNA kit
in combination with the
Maxwell RSC instrument
(
Promega
, Dübendorf, Switzerland). The same instrument was used for DNA isolation from
formalin-fixed paraffin-embedded
(176)
Comprehensive genetic profiling using tissue and blood in locally advanced tumors
Oncol Rep
August 5, 2025
Kenji Fujiyoshi, Rie Sugihara, Naoki Miyamoto, Yoriko Watanabe, Tomoya Sudo, Sanae Numata, Jun Akiba, Hideyuki Abe, Yuka Ichinose, Kenji Inoue,
et al.
quantification DNA and RNA from FFPE tissue specimens were extracted using a
Maxwell RSC Instrument
(cat. no.
AS4500
;
Promega
, Corp.),
Maxwell RSC FFPE Plus DNA kit
(cat. no.
AS1720
;
Promega
, Corp.) and
Maxwell RSC RNA FFPE kit
(177)
Accurate genotyping of three major respiratory bacterial pathogens with ONT R10.4.1 long-read sequencing
Genome Research
August 1, 2025
Nora Zidane, Carla Rodrigues, Valérie Bouchez, Martin Rethoret-Pasty, Virginie Passet, Sylvain Brisse, Chiara Crestani
standardized conditions, as previously described (Bouchez et al. 2018). DNA extraction was performed on a
Maxwell RSC instrument
(
Promega
) with the
Maxwell RSC Blood DNA Kit
(
Promega
) following the manufacturer's instructions. Library
(178)
Identifying Genetic Variations in emm89 Streptococcus pyogenes Associated with Severe Invasive Infections
Elife
July 24, 2025
Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara,
et al.
mg/ml RNase A (Promega, Madison, WI, USA). Next, genomic DNA was extracted from each lysate using a
Maxwell RSC instrument
(
Promega
), according to the manufacturer’s instructions, and 250 bp paired-end libraries were then generated
(179)
A predictive endocrine resistance index accurately stratifies luminal breast cancer treatment responders and nonresponders
J Clin Invest
July 24, 2025
Guokun Zhang, Vindi Jurinovic, Stephan Bartels, Matthias Christgen, Henriette Christgen, Leonie Donata Kandt, Lidiya Mishieva, Hua Ni, Mieke Raap, Janin Klein,
et al.
microdissection
to enrich for invasive
tumor
cells, DNA was extracted using the
Maxwell RSC DNA FFPE kit
on a
Maxwell RSC instrument
(
Promega
), and quality control tested (post-QC, discovery cohort, n = 362; validation cohort 1, n =
(180)
FGFR4 p.Gly388Arg polymorphism in PBMCs of LAM patients: findings of a pilot study
Frontiers in Medicine
July 24, 2025
Sinem Koc-Gunel, Amy L. Ryan, Melanie Winter, Thomas O. F. Wagner
platelets
and Ficoll. DNA extraction and quantification Genomic DNA was (13) extracted using the
Maxwell® RSC Instrument
(
Promega Corporation
, Madison, Wisconsin, United States) with the
Maxwell® RSC FFPE Plus DNA Kit
(
Promega Corporation
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Maxwell RSC Instrument from Promega
Supplier Page
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