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Automated DNA/RNA Purification Sample Preparation Workstations
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
Be the first to write a review!
Citations:
(881)
Figures:
(1)
Supplier Page
Supplier Page from
Promega for
Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV Lamp
Avg. lifetime approximately 6,000 hrs
Molecular Weight
~85kDa
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (881)
(181)
Blood collection tube and RNA purification method recommendations for extracellular RNA transcriptome profiling
Nat Commun
May 15, 2025
The exRNAQC Consortium
(
Promega
, AX5740 and
AS1680
) in combination with the
Maxwell RSC Instrument
(Maxwell method;
Promega
,
AS4500
), and MagNA Pure 24 Total NA Isolation Kit (Roche, 07658036001) in combination with the MagNA Pure 24
(182)
Novel cross-feeding human gut microbes metabolizing tryptophan to indole-3-propionate
Gut Microbes
May 8, 2025
Janina N. Zünd, Denisa Mujezinovic, Markus Reichlin, Serafina Plüss, Marina Caflisch, Serina Robinson, Christophe Lacroix, Benoit Pugin
rcf for 5 min. The DNA from fecal cultures incubated with tryptophan was further purified using the
Maxwell® RSC instrument
and the
Maxwell® RSC PureFood GMO and Authentication Kit
(
Promega
). The DNA from fecal cultures incubated
(183)
Clonal hematopoiesis in patients with cancer and its association with risk of thrombosis and prognosis of disease
Research and Practice in Thrombosis and Haemostasis
May 8, 2025
Cornelia Englisch, Roland Jäger, Jasmina Gassner, Alice Assinger, Matthias Preusser, Peter Valent, Ingrid Pabinger, Cihan Ay
preparation DNA was isolated from patients’ peripheral blood samples using the
Maxwell RSC Blood DNA Kit
on a
Maxwell RSC Instrument
(
Promega
). Routine parameters including hemoglobin,
platelet
and leucocyte counts,
red cell distribution width
(184)
Identification and characterization of tertiary lymphoid structures in brain metastases
Acta Neuropathol Commun
May 3, 2025
Sadaf S. Mughal, Yvonne Reiss, Jörg Felsberg, Lasse Meyer, Jadranka Macas, Silja Schlue, Tatjana Starzetz, Karl Köhrer, Tanja Fehm, Volkmar Müller,
et al.
of ≥ 80% were used for RNA extraction. RNA was extracted using the
Maxwell® RSC RNA FFPE kit
and the
Maxwell® RSC instrument
(
Promega
, Mannheim, Germany) as recommended by the manufacturer.
RNA sequencing
Total RNA samples
(185)
RNA sequencing driven diagnosis expands the phenotypic spectrum of NBAS deficiency
Molecular Genetics and Metabolism
May 1, 2025
Sarah Silverstein, Thomas Cassini, Jiayu Fu, Barbara Pusey, Ellen Macnamara, F Graeme Frost, Charlotte Williams, Yan Huang, Cynthia J. Tifft, Undiagnosed Diseases Network,
et al.
(
A1285901
,
Gibco
/ThermoFisher), washed with PBS and pelleted. Total RNA was extracted using Maxwell® RSC (
AS4500
,
Promega
) and
Maxwell® RSC simplyRNA Cells Kit
(
AS1390
,
Promega
) following manufacturer’s instructions.
(186)
Identifying Rare Germline Variants Associated with Metastatic Prostate Cancer Through an Extreme Phenotype Study
medRxiv
April 30, 2025
Yen-Yi Lin, Hamideh Sharifi Sharifi Noghabi, Stanislav Volik, Robert Bell, Funda Sar, Anne Haegert Haegert, Hee Chul Chung, Ladan Fazli, Htoo Zarni Zarni Oo, Mads Dauggard,
et al.
tumour and matched distant benign tissues was extracted using the
Maxwell RSC DNA FFPE kit
and with the
Maxwell RSC instrument
(
Promega
) according to the manufacturer’s instructions. The quality and quantity of the extracted DNA
(187)
Hypericin Suppresses SARS-CoV-2 Replication and Synergizes with Antivirals via Dual Targeting of RdRp and 3CLpro
Microorganisms
April 27, 2025
Helena da Silva Souza, Jéssica Santa Cruz Carvalho Martins, Thiagos das Chagas Sousa, Saiqa Sardar, Natalia Fintelman-Rodrigues, Lina Silva-Trujillo, Thiago Moreno Lopes e Souza, Marilda Mendonça Siqueira, Jorge Hernandes Fernandes, Aline da Rocha Matos
were collected for viral
RNA quantification
by
real-time RT-PCR
. Total RNA was extracted using the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA), according to the manufacturer’s instructions. Quantitative
RT-PCR
was performed
(188)
Genomic epidemiology of Salmonella Enteritidis human infections in the Netherlands, 2019 to 2023
Microb Genom
April 23, 2025
Linda E. Chanamé Pinedo, Eelco Franz, Timothy J. Dallman, Claudia E. Coipan, Roxanne Wolthuis, Kees T. Veldman, Lapo Mughini-Gras, Roan Pijnacker, Maaike J.C. van den Beld
performed using either the GenElute Bacterial Genomic DNA kit (Sigma-Aldrich, Inc.) or automated with the
Maxwell® RSC Instrument
using the
cultured cells
DNA kit (
Promega
Corp.), both according to the manufacturers' protocol. Library
(189)
Epileptic encephalopathy in a young Bengal cat caused by CAD deficiency
Sci Rep
April 18, 2025
Adriana Kaczmarska, Matthias Christen, Francisco Del Caño-Ochoa, Santiago Ramon-Maiques, Ana Cloquell Miro, Angie Rupp, Vidhya Jagannathan, Tosso Leeb, Rodrigo Gutierrez-Quintana
investigation Genomic DNA was extracted from EDTA blood samples using the Maxwell RSC Whole Blood Kit and the
Maxwell RSC instrument
(
Promega
, Dübendorf, Switzerland). An Illumina TruSeq DNA
PCR
-free library from the affected cat was
(190)
Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progression
Nat Commun
April 17, 2025
Akikazu Harada, Yoshiaki Yasumizu, Takeshi Harada, Katsumi Fumoto, Akira Sato, Natsumi Maehara, Ryota Sada, Shinji Matsumoto, Takashi Nishina, Kiyoshi Takeda,
et al.
203-15263) or 200 μM CoCl2 (Nacalai Tesque; Cat. 09206-92) for 24 h, and total RNA was isolated using
Maxwell RSC instrument
with
Maxwell RSC simplyRNA cells kit
(
Promega
, Madison, WI, USA; Cat.
AS1390
). Library preparation was
(191)
NTRK1 Gene Fusions Are Frequent in Juvenile Xanthogranuloma
American Journal of Surgical Pathology
April 16, 2025
Elisabeth Schlögl, Helga Hürner-Unterberger, Ingrid Simonitsch-Klupp, Gabriele Amann, Jaqueline Blank-Foltin, Barbara Neudert, Lisa Wozelka-Oltjan, Christine Haberler, Georg Ebetsberger-Dachs, Leonhard Müllauer
Plus DNA Kit (Promega), whereas RNA was extracted using the
Maxwell RSC RNA FFPE Kit
(
Promega
) on a
Maxwell RSC instrument
(
Promega
). DNA concentrations were quantified using the
Qubit dsDNA HS Assay Kit
(
Thermo Fisher Scientific
)
(192)
NTRK1 Gene Fusions Are Frequent in Juvenile Xanthogranuloma
Am J Surg Pathol
April 16, 2025
Elisabeth Schlögl, Helga Hürner-Unterberger, Ingrid Simonitsch-Klupp, Gabriele Amann, Jaqueline Blank-Foltin, Barbara Neudert, Lisa Wozelka-Oltjan, Christine Haberler, Georg Ebetsberger-Dachs, Leonhard Müllauer
Plus DNA Kit (Promega), whereas RNA was extracted using the
Maxwell RSC RNA FFPE Kit
(
Promega
) on a
Maxwell RSC instrument
(
Promega
). DNA concentrations were quantified using the
Qubit dsDNA HS Assay Kit
(
Thermo Fisher Scientific
)
(193)
Transmissibility of a new Plasmodium falciparum 3D7 bank for use in malaria volunteer infection studies evaluating transmission blocking interventions
Sci Rep
April 16, 2025
Sean A. Lynch, Azrin N. Abd-Rahman, Jenny M. Peters, Juanita M. Heunis, Jeremy S.E. Gower, Adam J. Potter, Rebecca Webster, Helen Jennings, Susan Mathison, Nischal Sahai,
et al.
samples incubated for 30 min at 65 °C. DNA was extracted as per Manufacturer’s instructions using the
Maxwell® RSC Instrument
(
Promega
) and eluted into 100 μL elution buffer.
qPCR
assays
were performed as previously described18. Outcomes The
(194)
Antiviral Effect of Erdosteine in Cells Infected with Human Respiratory Viruses
Pathogens
April 15, 2025
Pierachille Santus, Sergio Strizzi, Fiammetta Danzo, Mara Biasin, Irma Saulle, Claudia Vanetti, Marina Saad, Dejan Radovanovic, Daria Trabattoni
48 h post-
infection
(hpi). The total RNA was extracted from the
cell culture
supernatant using the
Maxwell RSC Instrument
with the
Maxwell RSC Viral Total Nucleic Acid Purification Kit
(
Promega
, Fitchburg, WI, USA) according
(195)
Closed genome sequence of Fretibacterium fastidiosum , a potential contributor to periodontal disease
Microbiology Resource Announcements
April 10, 2025
Asuka Mori, Mashu Kudoh, Masae Kuboniwa, Christian Rückert-Reed, Tobias Busche, Marion Eisenhut, Eiichiro Fukusaki, Andrea Bräutigam, Bianca Laker
DNA was isolated using the
Maxwell RSC Cultured Cells DNA Kit
(
Promega
, Madison, Wisconsin, US) and
Maxwell RSC Instrument
(
Promega
). The DNA quality and quantity were assessed with the Tape Station (Agilent) and the
Qubit fluorometer
(196)
Apomixis at a high resolution: unravelling diplospory in Asteraceae
Journal of Experimental Botany
April 9, 2025
Letizia Cornaro, Camilla Banfi, Alex Cavalleri, Peter J van Dijk, Tatyana Radoeva, Mara Cucinotta, Lucia Colombo
were ground together. Total RNA extraction was performed using the
Maxwell RSC Plant RNA Kit
with the
Maxwell RSC Instrument
(
Promega Corporation
). RNA integrity and quantity were measured with an
Agilent RNA 6000 Nano Kit
(
Agilent Technologies
(197)
Case Report: FGFR2 inhibitor resistance via PIK3CA and CDKN2A/B in an intrahepatic cholangiocarcinoma patient with FGFR2-SH3GLB1 fusion
Front Oncol
April 7, 2025
Nadja Ballin, Alexander Ott, Olga Seibel-Kelemen, Irina Bonzheim, Dominik Nann, Janina Beha, Stephan Spahn, Stephan Singer, Stephan Ossowski, Cristiana Roggia,
et al.
macrodissected 5μm paraffin sections using the
Maxwell RSC DNA FFPE Kit
and
Maxwell RSC RNA FFPE Kit
and the
Maxwell RSC Instrument
(
Promega
, Madison, WI, USA) according to the manufacturer’s instructions. DNA concentrations were determined
(198)
Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models
Elife
April 3, 2025
Ulrike Pech, Jasper Janssens, Nils Schoovaerts, Sabine Kuenen, Carles Calatayud Calatayud Aristoy, Sandra F Gallego, Samira Makhzami, Gert J Hulselmans, Suresh Poovathingal, Kristofer Davie,
et al.
US). Quantitative
RT-PCR
For each sample, 20 heads of 5-day-old males were collected, RNA was extracted using
Maxwell RSC instrument
and Maxwell RSC RNA kit (
Promega
) and transcribed using the SuperScriptIII synthesis system (Thermo
(199)
Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models
Elife
April 3, 2025
Ulrike Pech, Jasper Janssens, Nils Schoovaerts, Sabine Kuenen, Carles Calatayud Aristoy, Sandra F Gallego, Samira Makhzami, Gert J Hulselmans, Suresh Poovathingal, Kristofer Davie,
et al.
US). Quantitative
RT-PCR
For each sample, 20 heads of 5-day-old males were collected, RNA was extracted using
Maxwell RSC instrument
and Maxwell RSC RNA kit (
Promega
) and transcribed using the SuperScriptIII synthesis system (Thermo
(200)
Clade IIb Mpox virus (MPXV) vertical transmission and fetal demise in a pregnant rhesus macaque model
PLoS One
April 1, 2025
Nicholas P. Krabbe, Ann M. Mitzey, Saswati Bhattacharya, Elaina R. Razo, Xiankun Zeng, Nell Bekiares, Amy Moy, Amy Kamholz, Julie A. Karl, Gregory Daggett,
et al.
amniotic fluid and eluates from swab samples) using the Viral Total
Nucleic Acid Purification
Kit for the
Maxwell RSC instrument
(
Promega
, Madison WI) with the following modifications. After the addition of the lysis solution, samples
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Maxwell RSC Instrument from Promega
Supplier Page
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