Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(81) Pediatric H3 G34-mutant diffuse hemispheric glioma: clinical, imaging and molecular prognostic factors, MGMT expression, and temozolomide responseActa NeuropatholMarch 2, 2026Dana Tlais, Qunyu Zhang, Jordan T. Roach, Christopher L. Tinkle, Tong Lin, Xiaoyu Li, Ayatullah Mostafa, Daniel C. Moreira, Rene Y. McNall-Knapp, Sarah Z. Rush, et al.guidelines. Whole genome sequencing Genomic DNA was extracted from snap-frozen tumor tissue using an automated Maxwell RSC Instrument (Promega), as previously described [6, 15, 18]. DNA quality was assessed on a 4200 TapeStation (Agilent).

(82) Impact of Heterogeneous DNA Methylation on the Accuracy of Quantitative Methylation-Specific PCR for Detecting DNA Hypermethylation in Prostate CancerInternational Journal of Molecular SciencesFebruary 27, 2026Wieke C. H. Visser, Hans de Jong, Laureen B. Janssen, Jolly Shrivastava, Peter F. A. Mulders, Jack A. Schalken, Willem J. G. MelchersUSA) to concentrate large-volume urine samples prior to extraction, followed by extraction using the Maxwell RSC Instrument (Promega Corporation, Madison, WI, USA), with the Maxwell RSC miRNA Plasma and Serum Kit (cat. no. AS1460,

(83) Prospective multicenter study of ctDNA versus tumor tissue guiding FGFR-targeted therapy in metastatic urothelial cancerNature CommunicationsFebruary 27, 2026David C. Müller, Andrew J. Murtha, Jack V. W. Bacon, Maria Stephenson, Connor Wells, Carlos Vasquez-Rios, Kimia Rostin, Lisa Rebane, Elena Schönlau, Jussi Nikkola, et al.using the QIAGEN DNeasy Blood and Tissue Kit, or the Promega Maxwell® RSC Blood DNA Kit and Promega Maxwell® RSC Instrument. Extracted gDNA was quantified with a NanoDrop spectrophotometer. cfDNA libraries were generated using

(84) Parasitic surveillance in wolves of central Italy: a focus on the Abruzzo regionParasites & VectorsFebruary 21, 2026Sabrina Vanessa Patrizia Defourny, Mariasole Colombo, Gianluca D’Amico, Stefania Salucci, Antonio Cocco, Maria Chiara Cantelmi, Daniela Averaimo, Marco Rulli, Gianfranco Romeo, Susanna Tora, et al.min. DNA was extracted from the sediment using the standardized lysis and purification protocol of the Maxwell RSC® Instrument Genomic Kit (Promega, Madison, WI, USA). DNA was analyzed by real-time PCR (qPCR) [23] to detect Leishmania

(85) Enhanced virulence of mpox virus clade Ib over clade IIb in the CAST/EiJ mouse modelCommunications BiologyFebruary 11, 2026Alazne R. Unanue, Rocío Martín, Carolina Sánchez, Isabel Alonso-Sánchez, Ana Moraga-Quintanilla, Laura Fernandez del Ama, Pedro J. Sánchez-Cordón, Antonio Alcamí, Bruno HernáezDNA was isolated from homogenized MPXV infected organs using Maxwell RSC Viral TNA kit (Promega) and Maxwell RSC instrument (Promega) and finally eluted in 50 μl nuclease free water. We set up a multiplex RT-qPCR to detect viral

(86) Detection of structural DNA variants in medulloblastomas using optical genome mappingActa Neuropathologica CommunicationsFebruary 11, 2026Nadezhda Kubon, Mirela Bălan, David Koppstein, Sophia Praeger, Marietta Wolter, Peter Ebert, David Pauck, Jörg Felsberg, Thomas Beez, Daniel Picard, et al.extracted from fresh-frozen MB tissue samples (n = 29) using the Maxwell® RSC simplyRNA Tissue Kit and Maxwell® RSC Instrument (Promega). RNA sequencing libraries were prepared either with the Illumina Stranded Total RNA Prep,

(87) Rapid Drug Sensitivity Profiling via a Novel High-Success-Rate Culture Method for Patient-Derived Pancreatic Cancer: An Exploratory Preclinical Platform for Advancing Clinical Applications and Drug DevelopmentCellsFebruary 7, 2026Yu Kato, Naoki Yamamoto, Yuichiro Uchida, Noriko Hiramatsu, Takato Ozeki, Yukari Minobe, Yukika Hasegawa, Sho Kawabe, Hikaru Yabuuchi, Seiji Yamada, et al.passage) using Maxwell® RSC Cultured Cell DNA Kit (Cat No. AS1620; Promega, Madison, WI, USA) with a Maxwell® RSC Instrument according to the manufacturer’s instructions. DNA concentration was quantified using a Quantus Fluorometer

(88) Enhancing the accuracy of molecular classification of pediatric CNS tumors: a dual-classifier approach using DNA methylation profilingFrontiers in OncologyFebruary 5, 2026Esra Moosa, Rania Alanany, Shimaa Sherif, Erdener Ozer, Sukoluhle Dube, Aayesha Jabeen, Apryl Sanchez, Asma Jamil, Aisha Khalifa, Chiara Cugno, et al.(#69504, Qiagen) or the Maxwell® RSC Tissue DNA Kit (AS1610, Promega) on the Maxwell RSC instrument (AS4500, Promega) following the manufacturers’ protocols. Two pathologists (W.M. and E.O.) and one research

(89) Cytoplasmic poly-adenosine binding proteins modulate susceptibility of mRNAs to Pumilio-mediated decayNucleic Acids ResFebruary 5, 2026Katherine M McKenney, Carmen Hernandez-Perez, Elise B Dunshee, John M Pum, Anna J DesMarais, Robert P Connacher, Aaron C Goldstrohmfor 5 min. RNA was purified from the cell pellet using the SimplyRNA Cells kit (Promega, AS1390) and Maxwell RSC instrument following the manufacturer’s protocol. For the on-bead DNase digestion, the amount of DNase I (Promega,

(90) Strawberry atlas: Fragaria vesca gene expression atlas for strawberry genomicsPeerJFebruary 5, 2026Minto Odagiri, Chonprakun Thagun, Takeshi Kurokura, Tomohiro Suzuki, Yutaka Kodama, Yoshinori Fukasawaexpression Total RNA was extracted from each tissue using the Maxwell RSC Plant RNA kit together with the Maxwell RSC instrument (Promega, Madison, WI, USA) according to the manufacturer’s instructions. Extracted RNA was quantified

(91) A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity TestingAdvanced Healthcare MaterialsFebruary 3, 2026Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla Iglesias García‐Iglesias, Jagoda Litowczenko-Cybulska, Alba Morillas Garcia, Anton Guimerà, et al.(qRT‐PCR) Total RNA was isolated from the iPSC‐CFs using Maxwell RSC simply RNA Cells kit (Promega) and Maxwell RSC instrument (Promega) following manufacturer's instructions. 1 µg was used to synthesize cDNA using the Transcriptor first‐strand cDNA synthesis kit

(92) GJB6 missense variant in a Labrador Retriever with paw pad hyperkeratosisAnimal GeneticsFebruary 1, 2026Stefan J. Rietmann, Joseph Malatos, Vidhya Jagannathan, Tosso Leebwhole genome sequencing Genomic DNA was extracted from EDTA‐whole blood samples. The extraction was performed with a Maxwell™ RSC instrument using the Maxwell RSC Whole Blood DNA Kit (Promega, Dübendorf, Switzerland). For whole genome sequencing

(93) Basal cell adenoma with S100 protein–positive “stroma”: a distinct triphasic salivary gland neoplasm characterized by CTNNB1 mutationVirchows ArchivFebruary 1, 2026Alena Skálová, Martina Bradová, Jan Laco, Tomáš Vaněček, Veronika Hájková, Petr Martínek, Marián Grendár, Giulia Querzoli, Ilmo Leivo, Michal Michal(Thermo Fisher Scientific, Waltham, MA). RNA was extracted using the Maxwell RSC DNA FFPE Kit and the Maxwell RSC Instrument (Promega, Madison, WI) according to the manufacturer’s instructions and quantified using the Qubit HS

(94) Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade gliomaFrontiers in RadiologyJanuary 29, 2026Georg Gihr, Hans Henkes, Ali Khanafer, Mehdi Allouche, Oliver Ganslandt, Sebastian Johannes Müller, Walter Alexander Wohlgemuth, Stefan Schobparaffin-embedded tissue blocks using the Maxwell® RSC FFPE Plus DNA Kit AS1720 (Promega, Madison, WI, USA) and the Maxwell® RSC Instrument (Promega). The isolated DNA underwent bisulfite treatment using the EpiTect® Bisulfite Kit (QIAGEN,

(95) Methylation-specific, universal, and highly sensitive identification of ctDNA in prostate cancer by multiplex droplet digital PCRPLOS OneJanuary 29, 2026Søren Kahns, Ahmed H. Zedan, Mads M. Aagaard, Luisa M. D. Canto, Sanne Kjær-Frifeldt, Stine V. Eriksen, Christine V. Madsen, Jonna S. Madsen, Palle J. S. Osther, Torben F. Hansen, et al.mCRPC. Extraction of DNA from tissue, whole blood, and plasma DNA was extracted from FFPE biopsy specimens on the Maxwell RSC instrument using the Maxwell RSC FFPE Plus DNA Kit (Promega, Madison, WI, USA) according to the manufacturer’s

(96) Surveillance of avian influenza viruses in migratory wild birds in South Korea, 2019–2025Journal of Veterinary ScienceJanuary 26, 2026Jae Kyung Lee, Min Beom Kim, Seo Hyeon Kim, Song Hwi Jeong, HaanWoo Sung, Hyung-Kwan Jang, Kang-Seuk Choi, Daesung Yoo, Se-Hee An, Gyeong-Beom Heo, et al.described [17]. Briefly, Viral RNA was directly extracted from pooled fecal supernatant sample using the Maxwell RSC instrument with Maxwell RSC simplyRNA Tissue Kit (Promega, Korea), and AI virus matrix (M), H5, and H7 real-time

(97) PCB 153 Modulates Genes Involved in Proteasome and Neurodegeneration-Related Pathways in Differentiated SH-SY5Y Cells: A Transcriptomic StudyCellsJanuary 23, 2026Aurelio Minuti, Serena Silvestro, Claudia Muscarà, Michele Scuruchi, Simone D’AngioliniRNA was then extracted using the Maxwell® RSC simplyRNA Cells Kit (Promega, Madison, WI, USA) on the Maxwell® RSC Instrument, following the manufacturer’s protocol. Library preparation was performed using 100 ng of total RNA

(98) Meta-analyses of genome-wide association studies identify novel loci influencing Japanese white matter hyperintensitiesJournal of Human GeneticsJanuary 20, 2026Yuya Asanomi, Risa Mitsumori, Akiko Yamakawa, Takashi Morizono, Daichi Shigemizu, Shumpei Niida, Takashi Sakurai, Kouichi Ozakifrom the NCGG Biobank database. Genomic DNA was extracted from peripheral blood leukocytes using a Maxwell RSC Instrument and a Maxwell RSC Buffy Coat DNA Kit (Promega, Madison, WI, USA). Genome-wide genotyping of all subjects

(99) Targeting metabolic vulnerabilities: REV-ERB agonist SR9009 potentiates sorafenib efficacy in liver cancerCell Death DiscoveryJanuary 19, 2026Silvia Sabbioni, Paola Guerriero, Ram C. Shankaraiah, Laura Masatti, Angelo Michilli, Cristian Bassi, Lucilla D’Abundo, Farzaneh Moshiri, Bruno De Siena, Edi Simoni, et al.protein expression. RNA purification Total RNA was extracted from frozen liver cells or tissues using a Maxwell RSC instrument (Promega Italia, Milan) and a Maxwell RSC miRNA from a tissue purification kit (#AS1460, Promega) according

(100) Germline variants in ATM, BRCA2, other cancer predisposition and novel candidate genes are implicated in glioma risk in adult glioma patients with a familial or personal history of tumorsActa NeuropathologicaJanuary 17, 2026Frank Brand, Lily S. Rose, Amir H. Akbarzadeh, Christine A. M. Weber, Isabel Eckert, Gunnar Schmidt, Bernd Auber, Alisa Förster, Ulrike Beyer, Robert Geffers, et al.tumor sections. DNA was extracted using the Maxwell RSC DNA FFPE Kit (Promega, Madison, WI, USA) and a Maxwell RSC Instrument (Promega). For TMB detection, 15 ng tumor DNA was used in an Oncomine Tumor Mutation Load Assay (n =

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