Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(81) Germline Mutations in DNA Repair Genes in Patients with Pancreatic Neuroendocrine Neoplasms: Diagnostic and Therapeutic ImplicationsCurrent OncologyNovember 10, 2025Beata Jurecka-Lubieniecka, Małgorzata Ros-Mazurczyk, Aleksandra Sygula, Alexander J. Cortez, Marcela Krzempek, Anna B. Tuleja, Agnieszka Kotecka-Blicharz, Marta Cieslicka, Malgorzata Oczko-Wojciechowska, Daria Handkiewicz-JunakVacutainer® tubes. Genomic DNA was isolated from leukocytes using the Maxwell® RSC Blood DNA Kit on the Maxwell® RSC Instrument (Promega GmbH, Madison, WI, USA). DNA concentration and quality were assessed using the Qubit® 2.0 fluorometer

(82) Altered expression of autophagy-related molecules and β-catenin in different subtypes of thyroid cancer: co-localization in intranuclear cytoplasmic inclusionsEndocrine JournalNovember 4, 2025Yerkezhan Sailaubekova, Katsuya Matsuda, Yuko Akazawa, Hirokazu Kurohama, Yuki Matsuoka, Keiji Suzuki, Adiya Kerimbayeva, Hisayoshi Kondo, Van Phu Thang Nguyen, Thi Ngoc Anh Nguyen, et al.56°C. DNA extraction was performed using a Maxwell RSC DNA FFPE kit (Promega, Madison, WI, USA) and Maxwell RSC instrument (Promega), according to the manufacturer’s protocols. The concentration of double-strand DNA was quantified

(83) Oxford Nanopore Technologies [ONT] Sequencing: Clinical Validation in Genetically Heterogeneous DisordersGenes (Basel)November 3, 2025Mario Urtis, Chiara Paganini, Viviana Vilardo, Antonio Tescari, Samantha Minetto, Claudia Cavaliere, Andrea Pilotto, Carmela Giorgianni, Alessia Cattaneo, Marilena Tagliani, et al.Supplementary Table S1. 2.4. DNA Isolation DNA previously extracted from peripheral blood samples by Maxwell RSC Instrument (Promega, Madison, WI, USA) using Maxwell CSC Blood DNA Kit (Promega) according to the manufacturer’s

(84) Collective homeostasis of condensation-prone proteins via their mRNAsNatureNovember 1, 2025Faraway R, Costello Heaven N, Digby H, Kuret Hodnik K, Rebselj J, Wilkins OG, Chakrabarti AM, Iosub IA, Vadnjal N, Dore R, et al.extractions were performed from cell pellets using the Maxwell RSC simplyRNA kit (Promega) using a Maxwell RSC Instrument (Promega). 3′ End sequencing For each sample, 250 ng µl−1 of RNA was fragmented in 10 mM Tris-HCl

(85) TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast CancerAdvanced ScienceNovember 1, 2025Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, et al.silenced cells using the Maxwell RSC miRNA Tissue kit (AS1460, Promega) with the Maxwell RSC Instrument (AS4500, Promega). cDNA preparation was performed using the i‐Script reverse transcription Supermix Real Time

(86) Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer's diseaseThe EMBO journalNovember 1, 2025Sepe S, Rey F, Mancheno-Ferris A, Bigi A, Fani G, Damiani D, Cabrini M, Marinelli E, Aguado J, Contu L, et al.extraction from mouse primary neurons, human cortical neurons and mouse brains total RNA was performed using Maxwell® RSC Instrument (Promega), with Maxwell® RSC simplyRNA Tissue Kit (Promega), following the manufacturer’s instructions.

(87) Preclinical biodistribution and toxicology assessment of an AAV5-based subretinal modifier gene therapy for retinitis pigmentosaFrontiers in MedicineOctober 29, 2025Arun Upadhyay, Selina Drag, Pushpendra Singh, Kalpana Rajanala, Rasappa Arumughamtissues were procured at Charles River Laboratories. DNA was isolated from study tissues using the Maxwell® RSC Instrument and Maxwell® RSC Blood DNA Kit (Promega, AS1400) and quantified by spectrophotometer (SpectraMax). Samples

(88) Loss of histone macroH2A1.1 causes kidney abnormalities secondary to a change in nutrient metabolizationSci AdvOctober 24, 2025René Winkler, Gemma Comas-Armangué, David Corujo, Adrián Sanz-Moreno, Julia Calzada-Wack, Shubhra Ashish Bhattacharya, Birgit Rathkolb, Nathalia Romanelli Vicente Dragano, Colina X. Qiao, Valentina Chiodi, et al.RNA was isolated from at least 20 mg of homogenized tissue using an automatic purification platform (Maxwell RSC Instrument, Promega, Madison, WI, USA) and the corresponding Maxwell RSC simplyRNA Tissue Kit (Promega) according

(89) Comparative Analysis of Concentration and Quantification Methods for Antibiotic Resistance Genes and Their Phage-Mediated Dissemination in Treated Wastewater and BiosolidsPathogensOctober 18, 2025Irene Falcó, Ana Allende, Francesca Cutrupi, Rosa Aznar, Gloria Sánchez, Pilar Truchadousing the Maxwell RSC Pure Food GMO and Authentication Kit (Promega, Southampton, UK) along with the Maxwell® RSC Instrument (Promega, UK). Briefly, 300 μL of the concentrated water samples or resuspended biosolids were added

(90) Malignant Potential of Thyroid Follicular Nodular Disease With Solid/Trabecular Components: A Case ReportPathology InternationalOctober 15, 2025Mayu Ueda, Katsuya Matsuda, Yusuke Mori, Hirokazu Kurohama, Hiroyuki Mishima, Koh‐Ichiro Yoshiura, Norisato Mitsutake, Hisakazu Shindo, Shinya Sato, Hiroyuki Yamashita, et al.Out‐N, In‐N, and the skin tumor using the Maxwell RSC DNA FFPE Kit (Promega, Madison, WI, USA) with the Maxwell RSC Instrument (Promega). Libraries were prepared from 50 ng of DNA using NEBNext FFPE DNA Repair Mix (Biolabs, Tokyo,

(91) RNA-seq Splicing Profile of the CDH1 Gene and Its Impact on the Clinical Pathogenicity Classification of CDH1 Variants: A Description of Alternative and Pathogenic Splicing PatternsCancers (Basel)October 14, 2025Molka Sebai, Roseline Tang, Yahia Adnani, Alice Fievet, Odile Cabaret, Marie-Aude Robert de Rancher, Nathalie Auger, Yasmina Elaribi, Houweyda Jilani, Jean-Marc Limacher, et al.extraction using Maxwell RSC SimplyRNA Blood kit (AS1380) (Promega Corporation, Madison, WI, USA) on Promega Maxwell RSC Instrument for LCLs and Maxwell RSC RNA FFPE kit (AS1440) for FFPE blocks. RNA yield and RNA quality were checked

(92) Impact of Light-Activated Nanocomposite with Erythrosine B on agr Quorum Sensing System in Staphylococcus aureusAntibiotics (Basel)October 11, 2025Larysa Bugyna, Ľubomír Švantner, Katarína Bilská, Marek Pribus, Helena BujdákováMD-01N-110/220, Major Science, Saratoga, CA, USA) and centrifuged (5 min, 10,413× g). For RNA isolation, a Maxwell RSC instrument (Promega, Madison, WI, USA) was used. A total of 600 µL of each sample, 10 µL of DNase (the Maxwell RSC miRNA Tissue Kit

(93) The Derkay Scale as a Predictor of Voice Dysfunction in Recurrent Respiratory Papillomatosis: Correlations Between Acoustic and Patient-Reported OutcomesJ Clin MedOctober 8, 2025Beata Miaśkiewicz, Elżbieta Gos, Aleksandra Panasiewicz, Paulina Krasnodębska, Dominika Oziębło, Monika Ołdak, Agata Szkiełkowskawas isolated from the collected tissue using the commercial Maxwell FSC DNA IQ Casework Kit and the Maxwell RSC instrument following the manufacturer’s protocol (Promega, Walldorf, Germany). Subsequently, virus genotyping was

(94) ALOXE3 missense variant in a Chihuahua with autosomal recessive ichthyosisAnim GenetOctober 7, 2025Carina Vinberg, Stefan J. Rietmann, Sara Soto, Vidhya Jagannathan, Susanne Åhman, Tosso Leebwhole genome sequencing Genomic DNA was extracted from EDTA blood samples using a Maxwell RSC Whole Blood Kit on a Maxwell RSC instrument (Promega, Dübendorf, Switzerland). For whole genome sequencing of the affected dog, a PCR‐free library

(95) RNA-seq dataset of land snails collected in AustraliaData BriefOctober 4, 2025Berenice Talamantes-Becerra, Wei-Shan Chang, Michelle Michie, Mike Hodda, Mariana Hopper, Valerie Caronprotocol of Maxwell ® RSC simplyRNA Tissue Kit (Promega A1340) and the Maxwell ® RSC Instrument (Cat. AS4500). The modification done to the protocol was the inclusion of 400 µL of lysis buffer to each cooled homogenate,

(96) Dissecting seed composition QTL from wild soybean: fine-mapping, candidate gene identification, and evaluation of introgression effects on agronomic performanceTheor Appl GenetOctober 3, 2025Elizabeth De Meyer, Anser Mahmood, Mariola Usovsky, Jason Gillman, Bing Yang, Jared Decker, Qijian Song, Clinton Meinhardt, Michael Dennigmann, Asheesh K. Singh, et al.trifoliate leaf set was collected from one plant per line. Total genomic DNA was extracted using a Promega Maxwell® RSC Instrument with the Maxwell® RSC PureFood GMO and Authentication Kit (Promega, Madison, WI, USA). DNA samples were

(97) A predictive endocrine resistance index accurately stratifies luminal breast cancer treatment responders and non-respondersJournal of Clinical InvestigationOctober 1, 2025Guokun Zhang, Vindi Jurinovic, Stephan Bartels, Matthias Christgen, Henriette Christgen, Leonie Donata Kandt, Lidiya Mishieva, Hua Ni, Mieke Raap, Janin Klein, et al.microdissection to enrich for invasive tumor cells, DNA was extracted using the Maxwell RSC DNA FFPE kit on a Maxwell RSC instrument (Promega), and quality control tested (post-QC, discovery cohort, n = 362; validation cohort 1, n =

(98) Development and Validation of a Scaffold‐Free Human Multilineage Spheroid Model for Early Stage Cholangiopathies Driven by Cholangiocyte SenescenceLiver InternationalOctober 1, 2025Cheuk‐Ting Wu, Anja Moncsek, Joachim Mertensin figure legends. RNA extraction was performed using the Maxwell RSC simply RNA Tissue Kit with the Maxwell RSC Instrument (Promega) according to the manufacturer's instructions. The concentration of extracted RNA was quantified

(99) A partially automated method for DNA extraction from marmoset hair follicles to avoid blood chimerismFrontiers in GeneticsSeptember 26, 2025Alexandra M. Stendahl, Qiangge Zhang, Ana C. Lima, Curtis Mello, James Nemesh, Sam Peterson, Jenna Castro, Fritzie T. Celino-Brady, Karina Ray, Xian Gao, et al.requires knowing a priori the DNA sequence of the host and twin. 2 Materials and equipment Promega’s Maxwell RSC instrument Vortex and centrifuge Thermal mixer for 1.5 mL centrifuge tubes Cell Lysis Solution (i.e., Qiagen Puregene

(100) Evaluating plasma adipokines and their cognate receptors, as biomarkers for non-invasive diagnosis of endometrial cancerBioscience ReportsSeptember 25, 2025Rebecca Karkia, Eshwa Zahra, Chaeyeoun Min, Kako Hirai, Evgeny Makarov, Emmanouil Karteris, Jayanta ChatterjeeMaxwell® RSC simplyRNA Blood Kit (Promega). The procedure involved lysis, DNase treatment and automated purification using the Maxwell® RSC Instrument. Blood samples stabilised in RNAlater were thawed before RNA extraction. Extracted RNA was stored at

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