Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(81) Dissecting seed composition QTL from wild soybean: fine-mapping, candidate gene identification, and evaluation of introgression effects on agronomic performanceTheor Appl GenetOctober 3, 2025Elizabeth De Meyer, Anser Mahmood, Mariola Usovsky, Jason Gillman, Bing Yang, Jared Decker, Qijian Song, Clinton Meinhardt, Michael Dennigmann, Asheesh K. Singh, et al.trifoliate leaf set was collected from one plant per line. Total genomic DNA was extracted using a Promega Maxwell® RSC Instrument with the Maxwell® RSC PureFood GMO and Authentication Kit (Promega, Madison, WI, USA). DNA samples were

(82) A predictive endocrine resistance index accurately stratifies luminal breast cancer treatment responders and non-respondersJournal of Clinical InvestigationOctober 1, 2025Guokun Zhang, Vindi Jurinovic, Stephan Bartels, Matthias Christgen, Henriette Christgen, Leonie Donata Kandt, Lidiya Mishieva, Hua Ni, Mieke Raap, Janin Klein, et al.microdissection to enrich for invasive tumor cells, DNA was extracted using the Maxwell RSC DNA FFPE kit on a Maxwell RSC instrument (Promega), and quality control tested (post-QC, discovery cohort, n = 362; validation cohort 1, n =

(83) Development and Validation of a Scaffold‐Free Human Multilineage Spheroid Model for Early Stage Cholangiopathies Driven by Cholangiocyte SenescenceLiver InternationalOctober 1, 2025Cheuk‐Ting Wu, Anja Moncsek, Joachim Mertensin figure legends. RNA extraction was performed using the Maxwell RSC simply RNA Tissue Kit with the Maxwell RSC Instrument (Promega) according to the manufacturer's instructions. The concentration of extracted RNA was quantified

(84) A partially automated method for DNA extraction from marmoset hair follicles to avoid blood chimerismFrontiers in GeneticsSeptember 26, 2025Alexandra M. Stendahl, Qiangge Zhang, Ana C. Lima, Curtis Mello, James Nemesh, Sam Peterson, Jenna Castro, Fritzie T. Celino-Brady, Karina Ray, Xian Gao, et al.requires knowing a priori the DNA sequence of the host and twin. 2 Materials and equipment Promega’s Maxwell RSC instrument Vortex and centrifuge Thermal mixer for 1.5 mL centrifuge tubes Cell Lysis Solution (i.e., Qiagen Puregene

(85) Evaluating plasma adipokines and their cognate receptors, as biomarkers for non-invasive diagnosis of endometrial cancerBioscience ReportsSeptember 25, 2025Rebecca Karkia, Eshwa Zahra, Chaeyeoun Min, Kako Hirai, Evgeny Makarov, Emmanouil Karteris, Jayanta ChatterjeeMaxwell® RSC simplyRNA Blood Kit (Promega). The procedure involved lysis, DNase treatment and automated purification using the Maxwell® RSC Instrument. Blood samples stabilised in RNAlater were thawed before RNA extraction. Extracted RNA was stored at

(86) Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer’s diseaseThe EMBO JournalSeptember 21, 2025Sara Sepe, Federica Rey, Alexandra Mancheno-Ferris, Alessandra Bigi, Giulia Fani, Devid Damiani, Matteo Cabrini, Eugenia Marinelli, Julio Aguado, Liliana Contu, et al.extraction from mouse primary neurons, human cortical neurons and mouse brains total RNA was performed using Maxwell® RSC Instrument (Promega), with Maxwell® RSC simplyRNA Tissue Kit (Promega), following the manufacturer’s instructions.

(87) Ocean warming drives tissue-wide metabolic reprogramming in a fishiScienceSeptember 19, 2025Billy Moore, Shannon McMahon, Michael Izumiyama, Taewoo Ryu, Timothy Ravasifish x 7 tissues) using a Maxwell RSC simplyRNA Tissue Kit (Promega, Madison, USA) and the associated Maxwell RSC Instrument (Promega, Madison, USA), following the manufacturers guidelines. The quality and quantity of extracted

(88) ROBIN: A unified nanopore-based assay integrating intraoperative methylome classification and next-day comprehensive profiling for ultra-rapid tumor diagnosisNeuro-OncologySeptember 17, 2025Simon Deacon, Inswasti Cahyani, Nadine Holmes, Graeme Fox, Rory Munro, Satrio Wibowo, Thomas Murray, Hannah Mason, Mark Housley, Daniel Martin, et al.from frozen tumor samples were extracted using the Promega Maxwell® RSC Blood DNA Kit on a Promega Maxwell® RSC Instrument as per the methodology stated in the RapidCNS2 supplementary methods.5 Samples were quantified using

(89) Challenges and predictive value of morphologic features in panfungal sequencing of formalin-fixed, paraffin-embedded tissues: A 5-year retrospective studyAmerican Journal of Clinical PathologySeptember 9, 2025Shane A Kaysen, Matt X Luo, Ryan C Shean, Kimberly E Hanson, Benjamin T Bradley, Gillian L HaleMaxwell 16 FFPE Plus LEV DNA Purification Kit (Promega), and DNA extraction for fresh tissue was performed using the Maxwell RSC instrument and Maxwell RSC Blood DNA Kit (Promega). Amplification targets were acquired with M13 forward and reverse

(90) FOXR2 activation is not exclusive of CNS neuroblastomaNeuro-OncologySeptember 8, 2025Alexa N Siskar, Emily Hanzlik, Maria F Cardenas, Mohammad K Eldomery, Soniya Pinto, Christopher L Tinkle, Qunyu Zhang, Xiaoyu Li, Tong Lin, Sandeep K Dhanda, et al.Whole Genome Sequencing and Analysis Genomic DNA was extracted from snap-frozen tumor tissue using an automated Maxwell RSC Instrument (Promega), as previously described.15,16,26 DNA quality was assessed on a 4200 TapeStation (Agilent).

(91) Myeloid sarcoma shows a high frequency of mutations activating the MAPK/ERK pathway and association with clonal hematopoiesisThe Journal of Pathology: Clinical ResearchSeptember 4, 2025Dominik Nann, Tim‐Colin Schade, Mathis Overkamp, Lejla Mahmutovic, Eyyub Bag, Stephan Forchhammer, Julia Slotta‐Huspenina, Ludmila Boudova, Karl Sotlar, Leticia Quintanilla‐Martinez, et al.5 μm paraffin sections using the Maxwell® RSC DNA FFPE Kit, the Maxwell® RSC RNA FFPE Kit, and the Maxwell® RSC Instrument (Promega, Madison, WI, USA) according to the manufacturer's instructions. Next‐generation sequencing

(92) Infant Botulism and Carbohydrate Blood Group Antigens: Preliminary Results from a Discordant Twin StudyThe Journal of Pediatrics: Clinical PracticeSeptember 1, 2025Haydee A. Dabritz, Mayuri V. Panditrao, Suchitra Pandey, Nir Dover, Jason R. Barash, Jessica M. Khouri, Jennifer S. ReadFUT2 Gene to Determine Secretor Status Genomic DNA was extracted from 100 μl buffy coats with the Maxwell RSC instrument, using the buffy coat kit, according to the manufacturer's protocol (Promega), and were eluted into

(93) Evaluating novel and conventional cell‐separation techniques for sexual assault investigationsJournal of Forensic SciencesSeptember 1, 2025Janine Schulte, Simon Egger, Sarah Kron, Eva Scheurer, Iris Schulzmanufacturer's protocol [37]. Samples (including cell fractions and reference samples) were extracted on a Maxwell® RSC Instrument (Promega Corporation, Madison, USA) using the Maxwell® FSC DNA IQ™ Casework Kit (Promega) [38], with

(94) A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental ContextMolecular Biology and EvolutionSeptember 1, 2025Esra Durmaz Durmaz Mitchell, Envel Kerdaffrec, Paul Schmidt, Thomas Flatt, Sebastian Kittelmanndirections were pooled. Total RNA was extracted using a Promega Maxwell RSC simplyRNA Tissue Kit and Maxwell RSC Instrument, following the manufacturer's protocol. TruSeq stranded mRNA-seq library preparation and sequencing

(95) EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement DisorderMovement DisordersSeptember 1, 2025Cleo Schwarz, Florian Bartenschlager, Olivia Kershaw, Judith Braun, Julien Guevar, Vidhya Jagannathan, Jörg T. Epplen, Wencke Reineking, Wolfgang Baumgärtner, Kailash P. Bhatia, et al.Extraction Genomic DNA was extracted from EDTA blood with either the Maxwell RSC whole blood DNA kit on a Maxwell RSC instrument (Promega, Madison, WI, USA) or by using a QIAamp DNA Mini Kit (Qiagen GmbH, Hilden, Germany) according

(96) Monitoring SARS‐CoV‐2 Dissemination in Wastewater and Virus Isolation in Cell Cultures: An Integrated Approach for Pathogen Detection and SurveillanceJournal of Cellular and Molecular MedicineSeptember 1, 2025Elena Radu, Tudor Emanuel Fertig, Laura Denisa Dragu, Ioana Mădălina Pitică, Marius Surleac, Ana Iulia Neagu, Lavinia Pană, Alexandra Păiş, Lilia Matei, Ionut‐Lucian Antone‐Iordache, et al.and run on a FastPrep24 machine for 40 s at 6 m/s. The RNA extraction was performed on Maxwell RSC AS4500 (Promega) device using the Viral RNA/DNA Extraction Kit from WW (Promega). Total viral RNA was eluted

(97) Vagococcus lutrae Isolation in a Cat with Feline Urological Syndrome in Italy: A Case ReportMicroorganismsAugust 29, 2025Daniela Averaimo, Sabrina Vanessa Patrizia Defourny, Alessandra Alessiani, Marco Rulli, Alexandra Chiaverini, Marco Di Domenico, Iolanda Mangone, Cinzia Pompilii, Vanessa Piersanti, Roberta Giancristofaro, et al.and vancomycin (1–16 µg/mL). DNA extraction was performed using the Maxwell® RSC Genomic DNA Kit on Maxwell® RSC Instrument (Promega, Milano, Italy), and DNA quantity and quality were evaluated with a Quantus™ Fluorometer (Promega,

(98) Sex-related differences in cell-free DNA and neutrophil extracellular traps in patients with hematologic malignanciesImmunol ResAugust 26, 2025Gaia Gnecco, Alessandro Davini, Arianna Valeriano, Patrizia Mancuso, Enrico Derenzini, Giuseppe Lamorte, Daniele Prati, Giovanna Talarico, Francesco Bertolini(Maxwell RSC ccfDNA Plasma Kit, Promega, Madison, WI, USA, AS1840) on an automatic extractor (Maxwell, Promega, Madison, WI, USA, AS4500) according to the manufacturer’s instructions and stored at − 20 °C. Neutrophil and lymphocyte counts

(99) In Vitro Assessment of a Novel Piranha‐Passivated Dental Implant Surface Against Oral Biofilm FormationClinical Oral Implants ResearchAugust 25, 2025Paula Nuevo, Leire Virto, Honorato Ribeiro‐Vidal, Javier Gil, Mariano Sanz13,000 r.p.m. for 3 min, and DNA was extracted from the pelleted cells using an automated DNA extractor (Maxwell RSC Instrument, Promega, Madison, USA), along with its corresponding commercial kit (Maxwell RSC Genomic DNA Kit, Promega,

(100) Soma-localized Rab39 inhibits synaptic autophagy by controlling trafficking of Atg9 vesiclesThe EMBO JournalAugust 21, 2025Ayse Kilic, Gokhan Ozturan, Dirk Vandekerkhove, Sabine Kuenen, Jef Swerts, Esther Muñoz Pedrazo, Carles Calatayud Aristoy, Abril Escamilla Ayala, Nikky Corthout, Pablo Hernández Varas, et al.was extracted from 10 adult Drosophila heads (5 males and 5 females, 5 days old) per sample using the Maxwell RSC Instrument and Maxwell RSC RNA Kit (Promega), according to the manufacturer’s instructions. First-strand cDNA synthesis

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