Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(101) Evaluating plasma adipokines and their cognate receptors as biomarkers for non-invasive diagnosis of endometrial cancerBiosci RepSeptember 22, 2025Rebecca Karkia, Eshwa Zahra, Chaeyeoun Min, Kako Hirai, Evgeny Makarov, Emmanouil Karteris, Jayanta ChatterjeeMaxwell® RSC simplyRNA Blood Kit (Promega). The procedure involved lysis, DNase treatment and automated purification using the Maxwell® RSC Instrument. Blood samples stabilised in RNAlater were thawed before RNA extraction. Extracted RNA was stored at

(102) Ocean warming drives tissue-wide metabolic reprogramming in a fishiScienceSeptember 19, 2025Billy Moore, Shannon McMahon, Michael Izumiyama, Taewoo Ryu, Timothy Ravasifish x 7 tissues) using a Maxwell RSC simplyRNA Tissue Kit (Promega, Madison, USA) and the associated Maxwell RSC Instrument (Promega, Madison, USA), following the manufacturers guidelines. The quality and quantity of extracted

(103) ROBIN: A unified nanopore-based assay integrating intraoperative methylome classification and next-day comprehensive profiling for ultra-rapid tumor diagnosisNeuro-OncologySeptember 17, 2025Simon Deacon, Inswasti Cahyani, Nadine Holmes, Graeme Fox, Rory Munro, Satrio Wibowo, Thomas Murray, Hannah Mason, Mark Housley, Daniel Martin, et al.from frozen tumor samples were extracted using the Promega Maxwell® RSC Blood DNA Kit on a Promega Maxwell® RSC Instrument as per the methodology stated in the RapidCNS2 supplementary methods.5 Samples were quantified using

(104) Challenges and predictive value of morphologic features in panfungal sequencing of formalin-fixed, paraffin-embedded tissues: A 5-year retrospective studyAmerican Journal of Clinical PathologySeptember 9, 2025Shane A Kaysen, Matt X Luo, Ryan C Shean, Kimberly E Hanson, Benjamin T Bradley, Gillian L HaleMaxwell 16 FFPE Plus LEV DNA Purification Kit (Promega), and DNA extraction for fresh tissue was performed using the Maxwell RSC instrument and Maxwell RSC Blood DNA Kit (Promega). Amplification targets were acquired with M13 forward and reverse

(105) FOXR2 activation is not exclusive of CNS neuroblastomaNeuro-OncologySeptember 8, 2025Alexa N Siskar, Emily Hanzlik, Maria F Cardenas, Mohammad K Eldomery, Soniya Pinto, Christopher L Tinkle, Qunyu Zhang, Xiaoyu Li, Tong Lin, Sandeep K Dhanda, et al.Whole Genome Sequencing and Analysis Genomic DNA was extracted from snap-frozen tumor tissue using an automated Maxwell RSC Instrument (Promega), as previously described.15,16,26 DNA quality was assessed on a 4200 TapeStation (Agilent).

(106) Myeloid sarcoma shows a high frequency of mutations activating the MAPK/ERK pathway and association with clonal hematopoiesisThe Journal of Pathology: Clinical ResearchSeptember 4, 2025Dominik Nann, Tim‐Colin Schade, Mathis Overkamp, Lejla Mahmutovic, Eyyub Bag, Stephan Forchhammer, Julia Slotta‐Huspenina, Ludmila Boudova, Karl Sotlar, Leticia Quintanilla‐Martinez, et al.5 μm paraffin sections using the Maxwell® RSC DNA FFPE Kit, the Maxwell® RSC RNA FFPE Kit, and the Maxwell® RSC Instrument (Promega, Madison, WI, USA) according to the manufacturer's instructions. Next‐generation sequencing

(107) A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental ContextMolecular Biology and EvolutionSeptember 1, 2025Esra Durmaz Durmaz Mitchell, Envel Kerdaffrec, Paul Schmidt, Thomas Flatt, Sebastian Kittelmanndirections were pooled. Total RNA was extracted using a Promega Maxwell RSC simplyRNA Tissue Kit and Maxwell RSC Instrument, following the manufacturer's protocol. TruSeq stranded mRNA-seq library preparation and sequencing

(108) Monitoring SARS‐CoV‐2 Dissemination in Wastewater and Virus Isolation in Cell Cultures: An Integrated Approach for Pathogen Detection and SurveillanceJournal of Cellular and Molecular MedicineSeptember 1, 2025Elena Radu, Tudor Emanuel Fertig, Laura Denisa Dragu, Ioana Mădălina Pitică, Marius Surleac, Ana Iulia Neagu, Lavinia Pană, Alexandra Păiş, Lilia Matei, Ionut‐Lucian Antone‐Iordache, et al.and run on a FastPrep24 machine for 40 s at 6 m/s. The RNA extraction was performed on Maxwell RSC AS4500 (Promega) device using the Viral RNA/DNA Extraction Kit from WW (Promega). Total viral RNA was eluted

(109) Infant Botulism and Carbohydrate Blood Group Antigens: Preliminary Results from a Discordant Twin StudyThe Journal of Pediatrics: Clinical PracticeSeptember 1, 2025Haydee A. Dabritz, Mayuri V. Panditrao, Suchitra Pandey, Nir Dover, Jason R. Barash, Jessica M. Khouri, Jennifer S. ReadFUT2 Gene to Determine Secretor Status Genomic DNA was extracted from 100 μl buffy coats with the Maxwell RSC instrument, using the buffy coat kit, according to the manufacturer's protocol (Promega), and were eluted into

(110) EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement DisorderMovement DisordersSeptember 1, 2025Cleo Schwarz, Florian Bartenschlager, Olivia Kershaw, Judith Braun, Julien Guevar, Vidhya Jagannathan, Jörg T. Epplen, Wencke Reineking, Wolfgang Baumgärtner, Kailash P. Bhatia, et al.Extraction Genomic DNA was extracted from EDTA blood with either the Maxwell RSC whole blood DNA kit on a Maxwell RSC instrument (Promega, Madison, WI, USA) or by using a QIAamp DNA Mini Kit (Qiagen GmbH, Hilden, Germany) according

(111) Evaluating novel and conventional cell‐separation techniques for sexual assault investigationsJournal of Forensic SciencesSeptember 1, 2025Janine Schulte, Simon Egger, Sarah Kron, Eva Scheurer, Iris Schulzmanufacturer's protocol [37]. Samples (including cell fractions and reference samples) were extracted on a Maxwell® RSC Instrument (Promega Corporation, Madison, USA) using the Maxwell® FSC DNA IQ™ Casework Kit (Promega) [38], with

(112) Vagococcus lutrae Isolation in a Cat with Feline Urological Syndrome in Italy: A Case ReportMicroorganismsAugust 29, 2025Daniela Averaimo, Sabrina Vanessa Patrizia Defourny, Alessandra Alessiani, Marco Rulli, Alexandra Chiaverini, Marco Di Domenico, Iolanda Mangone, Cinzia Pompilii, Vanessa Piersanti, Roberta Giancristofaro, et al.and vancomycin (1–16 µg/mL). DNA extraction was performed using the Maxwell® RSC Genomic DNA Kit on Maxwell® RSC Instrument (Promega, Milano, Italy), and DNA quantity and quality were evaluated with a Quantus™ Fluorometer (Promega,

(113) Sex-related differences in cell-free DNA and neutrophil extracellular traps in patients with hematologic malignanciesImmunol ResAugust 26, 2025Gaia Gnecco, Alessandro Davini, Arianna Valeriano, Patrizia Mancuso, Enrico Derenzini, Giuseppe Lamorte, Daniele Prati, Giovanna Talarico, Francesco Bertolini(Maxwell RSC ccfDNA Plasma Kit, Promega, Madison, WI, USA, AS1840) on an automatic extractor (Maxwell, Promega, Madison, WI, USA, AS4500) according to the manufacturer’s instructions and stored at − 20 °C. Neutrophil and lymphocyte counts

(114) In Vitro Assessment of a Novel Piranha‐Passivated Dental Implant Surface Against Oral Biofilm FormationClinical Oral Implants ResearchAugust 25, 2025Paula Nuevo, Leire Virto, Honorato Ribeiro‐Vidal, Javier Gil, Mariano Sanz13,000 r.p.m. for 3 min, and DNA was extracted from the pelleted cells using an automated DNA extractor (Maxwell RSC Instrument, Promega, Madison, USA), along with its corresponding commercial kit (Maxwell RSC Genomic DNA Kit, Promega,

(115) Soma-localized Rab39 inhibits synaptic autophagy by controlling trafficking of Atg9 vesiclesThe EMBO JournalAugust 21, 2025Ayse Kilic, Gokhan Ozturan, Dirk Vandekerkhove, Sabine Kuenen, Jef Swerts, Esther Muñoz Pedrazo, Carles Calatayud Aristoy, Abril Escamilla Ayala, Nikky Corthout, Pablo Hernández Varas, et al.was extracted from 10 adult Drosophila heads (5 males and 5 females, 5 days old) per sample using the Maxwell RSC Instrument and Maxwell RSC RNA Kit (Promega), according to the manufacturer’s instructions. First-strand cDNA synthesis

(116) Inter-Island Whole-Genome Comparison Reveals Micro-Evolutionary Dynamics of the Red Fox, Stimulated Through Post-Glacial Sea-Level AlterationsGenome Biol EvolAugust 21, 2025Takumi Watanabe, Shin Shinojima Satoh, Toshiaki Shiraishi, Shosei Kubota, Yuji YamazakiWhole-Genome Sequencing Genomic DNA (gDNA) was extracted from each sample using an automatic nucleic acid purification device Maxwell RSC Instrument (Promega Corp., Madison, WI, U.S.A.), following the protocol of the Maxwell RSC Tissue DNA Kit. Tissues

(117) Adjuvant anti-PD-1 therapy improves melanoma-specific survival in stage IIIC-IV melanoma patients with high tumor mutation burden and BRAF V600 mutationFront OncolAugust 12, 2025Julia Forschner, Julia Huynh, Christopher Schroeder, Sorin Armeanu-Ebinger, Olga Seibel-Kelemen, Axel Gschwind, Irina Bonzheim, Thomas K. Eigentler, Teresa Amaral, Stephan Ossowski, et al.DNA was isolated from tumor FFPE tissue and blood samples using the Maxwell® RSC DNA FFPE kit and the Maxwell® RSC instrument (Promega, Madison, WI, USA) according to the manufacturer’s standard protocols. After isolation, 200

(118) LMF1 frameshift deletion in Franches-Montagnes horses with hypertriglyceridemia-induced pancreatitisSci RepAugust 6, 2025Michaela Drögemüller, Nathalie Fouché, Michelle Wyler, Corinne Gurtner, Seraina L. Meister, Markus Neuditschko, Vidhya Jagannathan, Vinzenz Gerber, Tosso LeebDNA was extracted from EDTA blood using the Maxwell RSC Whole Blood DNA kit in combination with the Maxwell RSC instrument (Promega, Dübendorf, Switzerland). The same instrument was used for DNA isolation from formalin-fixed paraffin-embedded

(119) Detecting actionable mutations from matched plasma-based versus tissue next-generation sequencing in advanced non-small cell lung cancer: a retrospective single centre analysis on siteJ Exp Clin Cancer ResAugust 6, 2025Christophe Bontoux, Caroline Lacoux, Jonathan Benzaquen, Jacques Boutros, Guylène Rignol, Elodie Long-Mira, Sandra Lassalle, Maryline Allegra, Doriane Bohly, Mathieu Garcia, et al.cytological specimens and surgically resected specimens, using the Maxwell RSC Instrument (Promega, #AS4500) with the Maxwell RSC FFPE Plus DNA Kit (#AS1720) and Maxwell RSC RNA FFPE Kit (#AS1440). Extracted

(120) Comprehensive genetic profiling using tissue and blood in locally advanced tumorsOncol RepAugust 5, 2025Kenji Fujiyoshi, Rie Sugihara, Naoki Miyamoto, Yoriko Watanabe, Tomoya Sudo, Sanae Numata, Jun Akiba, Hideyuki Abe, Yuka Ichinose, Kenji Inoue, et al.quantification DNA and RNA from FFPE tissue specimens were extracted using a Maxwell RSC Instrument (cat. no. AS4500; Promega, Corp.), Maxwell RSC FFPE Plus DNA kit (cat. no. AS1720; Promega, Corp.) and Maxwell RSC RNA FFPE kit

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