Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(101) Molecular Responses to Temperature Changes Across Timescales in the Madagascar Ground Gecko ( Paroedura picta )Molecular EcologyJanuary 17, 2026Fuku Sakamoto, Shunsuke Kanamori, Félix Rakotondraparany, Takashi Makino, Masakado KawataTranscriptome Analysis Total RNA was extracted using the Maxwell RSC Plant RNA Kit and Maxwell RSC Instrument AS4500 (Promega, Madison, WI, USA). RNA concentration and purity were verified using a Nanodrop spectrophotometer

(102) Statistical and Evolutionary Analysis of Sequenced DNA from Breast Cancer FFPE SpecimensbioRxivJanuary 16, 2026Monika K. Kurpas, Paweł Kuś, Roman Jaksik, Khanh N. Dinh, Agnieszka Adamczyk, Kaja Majchrzyk, Marek KimmelTumor Pathology from macrodissected FFPE tissue samples using a semi-automatic method available from Maxwell® RSC Instrument (Promega) with the settings recommended by the manufacturer. The quality and amount of DNA was evaluated

(103) Contrasting whole-genome diversity patterns and adaptation in honeybees from two southern European glacial refugiaiScienceJanuary 16, 2026Carlos A. Yadró Garcia, Dora Henriques, Giovanni Cilia, José Rufino, Cristina Vella, Abdessamad Aglagane, Soledad Sagastume, Marion Zammit-Mangion, Raquel Martín-Hernández, Antonio Nanetti, et al.Italian and 26 A. m. sahariensis samples was extracted from the thorax of individual drones using the Maxwell® RSC Instrument (Promega, USA) with the Maxwell® RSC PureFood GMO and Authentication kit (Promega, USA). To investigate

(104) Polyamine-dependent metabolic shielding regulates alternative splicingNatureJanuary 14, 2026Amaia Zabala-Letona, Mikel Pujana-Vaquerizo, Belen Martinez-Laosa, Maria Ponce-Rodriguez, Saioa Garcia-Longarte, Isabel Mendizabal, Ana Gimeno, Malgorzata Rogalska, Joycelyn Tan, Diana Cabrera, et al.NucleoSpin RNA isolation kit from Macherey-Nagel (ref: 740955.240 C) or automatically extracted using Maxwell RSC instrument (Promega) according to the manufacturers’ instructions (Supplementary Methods). RNA-seq analysis The

(105) Early-life stages impact later feeding behavior and physiology in light-born pigletsJournal of Animal ScienceJanuary 8, 2026Elizabeth Huenul, Susana M Martín-Orúe, Lluís Fabà, Ruth Forsten, Pau Salgado-López, Ferran Llobet-Cabau, María José Rodríguez-Lagunas, Marta Fornós, José Francisco Pérezobtained using the Maxwell RSC simplyRNA Tissue Kit (Promega Corporation, Madison, WI, United States) in a Maxwell RSC instrument (Promega Corporation, Madison, WI, United States) following the manufacturer’s instructions. The quantity

(106) Effects of phage-based treatments against an OXA-48-producing Klebsiella pneumoniae isolate in simulated human gut microbiomesBMC MicrobiologyJanuary 8, 2026Celia Ferriol-González, Ana Hernanz-Grimalt, Carlos Valdivia, Silvia García-Cobos, Ana Heredia, Jorge García-Hernández, Ana Andrés, Pilar Domingo-CalapDNA extraction was performed using the Maxwell PureFood GMO and Authentication Kit (Promega) on the Maxwell RSC Instrument (Promega). Quantification of the K. pneumoniae complex was performed by qPCR targeting the zur-khe intergenic

(107) Targeted next-generation sequencing-based sequencing of cell-free DNA in cerebrospinal fluid uncovers cancer-specific mutations in patients with brain cancer using a widely available panelNeuro-Oncology AdvancesJanuary 7, 2026Alexander Köpp, Peter Westarp, Marta Nowak, Nils Briel, Maximilian Mastall, Adela Brzobohata, Roger Schenk, Michael Schmid, Emilie Le Rhun, Holger Moch, et al.extraction from formalin-fixed paraffin-embedded tissue, the Maxwell RSC DNA FFPE Kit (Promega) on a Maxwell RSC instrument (Promega) was used following the manufacturer’s protocol. Molecular Analysis Liquid biopsy specimens

(108) Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severityeBioMedicineJanuary 6, 2026Claudio Cappadona, Valeria Rimoldi, Francesca Tettamanzi, Giulia Cardamone, Alberto Mantovani, Giulia Soldà, Elvezia Maria Paraboschi, Rosanna AsseltaPromega Maxwell RSC Blood DNA Kit (Promega, Madison, Wisconsin, USA) on a benchtop automated extractor (Maxwell RSC Instrument, RRID:SCR_025867). Library preparation was performed using the SureSelect Human All Exon V7 kit (Agilent Technologies

(109) Epigenetic, histological and clinical characterization of preeclampsia in oocyte donation pregnancies: insights into immune dysregulation and microRNA-mediated pathwaysFrontiers in Cell and Developmental BiologyJanuary 5, 2026Irma Saulle, Maria Di Giminiani, Ozge Yazici, Claudio Fenizia, Manuela Nebuloni, Roberta Rossi, Mara Biasin, Valeria SavasimicroRNA tissue extraction respectively (Promega, Fitchburg, WI, United States) and extracted through the Maxwell® RSC Instrument (Promega, Fitchburg, WI, United States) according to manufacturer’s protocol (Saulle et al., 2023);

(110) Comparison of two digital PCR platforms for quantification of genetically modified soybean eventsGM Crops & FoodDecember 31, 2025Daniela Verginelli, Sara Ciuffa, Katia Spinella, Davide La Rocca, Daniela Villa, Alessandra Barbante, Elena Perri, Ugo MarchesiUrbana, IL, USA). DNA was extracted from 200 mg of CRMs using the RSC PureFood GMO kit with the extractor Maxwell®RSC Instrument (Promega Madison, WI, USA), according to the manufacturer’s instructions for the Bio-Rad platform and

(111) Autologous fecal microbiota capsules are safe and potentially preserve beta-cell function in individuals with type 1 diabetesGut MicrobesDecember 31, 2025Pleun de Groen, Coco M. Fuhri Snethlage, Koen Wortelboer, Sevilay Tokgöz, Mark Davids, Xanthe Verdoes, Florine H.M. Westerbeke, Rick I. Meijer, Martin Gotthardt, Willem M. de Vos, et al.protocol, and the purification of the lysates was done using the Maxwell® system (RSC Promega, Cat# AS4500). For both sample types, 300 µL S.T.A.R. buffer (Roche Diagnostics, Cat# 03335208001) was added to the

(112) Liver-specific loss of Atg9a perturbs lipid metabolism and hepatocyte integrityAutophagy ReportsDecember 31, 2025Elodie Mailler, Asmita Singh, Michal Jarnik, Yan Li, Lynne Holtzclaw, Victoria Hoffmann, Sohtaro Mine, Paulina Stallcup, Laleh Ordoubadinia, Carlos M. Guardiagene expression analysis RNA was purified from FFPE sections using the Maxwell RSC RNA FFPE Kit (Promega, AS1440) with the Maxwell RSC Instrument, following the manufacturer’s protocol. Briefly, 3–4 sections (~30 μm thickness) were combined in a

(113) Performance evaluation of the automated haematology analyzer XN-31 for malaria diagnosis in Plasmodium vivax-dominant regions of ThailandMalaria JournalDecember 29, 2025Miki Kawaguchi, Kanako Komaki-Yasuda, Masami Nakatsu, Nattha Kerdsakundee, Mieko Hamana, Takahiro Tougan, Mina Kamei, Aya Konishi, Srivicha Krudsood, Shigeyuki Kanospecies. PCR DNA was extracted using the Maxwell DNA FFPE Kit (Promega, Madison, WI, USA) and the automated Maxwell RSC Instrument (Promega) from a punched dried blood spot of 5 mm in diameter (approximately equivalent to 20–30 µL

(114) Germline BRCA1/2 Variants in Polish Patients with Family History of Breast and Ovarian Cancer: Prevalence, CNV Detection, and Identification of a Novel Loss-of-Function MutationCurrent OncologyDecember 24, 2025Sebastian Skoczylas, Tomasz Płoszaj, Izabela Dróżdż, Hanna Moczulska, Marcin Serafin, Katarzyna Piekarska, Olga Wojtyczka, Karolina Żeżawska, Agnieszka Zmysłowskatheir informed written consent to genetic testing. DNA was extracted from peripheral blood using the Maxwell® RSC Instrument (Maxwell® RSC Blood DNA Kit, Promega, Madison, WI, USA). Libraries were prepared using the Devyser BRCA

(115) Centriflaken: An automated data analysis pipeline for assembly and in silico analyses of foodborne pathogens from metagenomic samplesPLoS OneDecember 23, 2025Kranti Konganti, Julie A. Kase, Narjol Gonzalez-Escalonaenriched agricultural water sample was extracted using the Maxwell RSC Cultured Cell DNA Kit with a Maxwell RSC Instrument (Promega Corporation, Madison, WI, USA) according to the manufacturer’s instructions DNA concentration

(116) Claudin‐18 expression in gastric type adenocarcinoma and HPV ‐associated adenocarcinoma of the uterine cervixHistopathologyDecember 22, 2025Nobuko Yasutake, Yuki Yokawa, Takehiro Tanaka, Riri Mishima, Misato Komamizu, Ryosuke Kuga, Rina Jiromaru, Shinichiro Kawatoko, Kenzo Sonoda, Hideaki Yahata, et al.CLDN18.2 mRNA Expression Total RNA was extracted from FFPE samples using a Maxwell® RSC RNA FFPE Kit and Maxwell® RSC Instrument (Promega Corporation, Madison, WI, USA) according to the manufacturer's protocol. RNA concentrations

(117) Variant analysis and biochemical investigation in two siblings with late onset idiopathic secondary erythrocytosis: A case reportMedicine (Baltimore)December 19, 2025Vincenza Ylenia Cusenza, Beatrice Melli, Chiara Marraccini, Agnese Razzoli, Margherita Genitoni, Laura Albertazzi, Nesrine Gamal, Gaia Gavioli, Davide Nicoli, Enrico Farnetti, et al.peripheral blood sample using the Maxwell® 16 LEV Blood DNA kit (Maxwell® 16 LEV Blood DNA Kit) on the Maxwell® RSC instrument (Promega Corporation, Madison), according to the manufacturer’s specifications. DNA amplification by

(118) Variant analysis and biochemical investigation in two siblings with late onset idiopathic secondary erythrocytosis: A case reportMedicine (Baltimore)December 19, 2025Vincenza Ylenia Cusenza, Beatrice Melli, Chiara Marraccini, Agnese Razzoli, Margherita Genitoni, Laura Albertazzi, Nesrine Gamal, Gaia Gavioli, Davide Nicoli, Enrico Farnetti, et al.peripheral blood sample using the Maxwell® 16 LEV Blood DNA kit (Maxwell® 16 LEV Blood DNA Kit) on the Maxwell® RSC instrument (Promega Corporation, Madison), according to the manufacturer’s specifications. DNA amplification by

(119) Genome and transcriptome-wide association studies identify multiple novel loci for dementia with grain in JapaneseJournal of Human GeneticsDecember 17, 2025Risa Mitsumori, Kouichi Ozaki, Yuko Saito, Daichi Shigemizu, Atsushi Iwata, Shigeo Murayama, Masahiro Akishita, Tomio Arai, Shumpei Niida, Kenji TobaDNA from NCGG biobank was extracted from peripheral blood leukocytes by standard protocols using a Maxwell RSC Instrument and a Maxwell RSC Buffy Coat DNA Kit (Promega, Madison, WI, USA). Genomic DNA from TMIG was extracted

(120) Effects of Long-Term Ocean Acidification Exposure on the Structural, Mineralogical, and Mechanical Properties of Sea Urchin (Echinometra spp.) Skeletons at a Natural Volcanic CO2 SeepEnviron Sci TechnolDecember 16, 2025Callum J. Hudson, Jeffrey Jolly, Sean D. Connell, Timothy Ravasi, Ben P. Harveyextracted from the tissue using Promega Maxwell RSC Tissue DNA Kits (Promega, USA) and the associated Maxwell RSC Instrument according to the manufacturer’s protocols. The extracted DNA concentration was measured by fluorometry

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