Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(121) Quality Assessment of Discarded Human Kidneys Using Normothermic PerfusionTransplant DirectDecember 12, 2025Enrique Montagud-Marrahi, Thomas Prudhomme, Tarek Ajami, Cristina García-Parejo, Lluis Peri, Adriana Rodriguez-Gonzalo, Yosu Luque, Antoni Vilaseca, Ruben Rabadan-Ros, Elena Cuadrado-Payan, et al.Quantitative Polymerase Chain Reaction The samples were homogenized and total RNA was extracted using the Maxwell RSC Instrument (Promega, Madrid, Spain). Total kidney RNAs were extracted using the Maxwell RSC miRNA Tissue Kit (Promega,

(122) Identification of Intronic Variants in NDUFA3 as a Cause of Leigh Syndrome by Whole Genome Sequencing and RNA SequencingNeurol GenetDecember 11, 2025Kohta Nakamura, Yoshihito Kishita, Ayumu Sugiura, Kokoro Ozaki, Yukiko Yatsuka, Naoyuki Matsumoto, Atsuko Okazaki, Holger Prokisch, Koichi Maruyama, Hiroyasu Iwasa, et al.RNA Sequencing RNA was purified from patient-derived skin fibroblasts by the Maxwell RSC simplyRNA Cells Kit and a Maxwell RSC Instrument (Promega). mRNA was enriched using oligo (dT) beads and rRNA removed using the Illumina Ribo-Zero kit.

(123) Identification of Intronic Variants in NDUFA3 as a Cause of Leigh Syndrome by Whole Genome Sequencing and RNA SequencingNeurol GenetDecember 11, 2025Kohta Nakamura, Yoshihito Kishita, Ayumu Sugiura, Kokoro Ozaki, Yukiko Yatsuka, Naoyuki Matsumoto, Atsuko Okazaki, Holger Prokisch, Koichi Maruyama, Hiroyasu Iwasa, et al.RNA Sequencing RNA was purified from patient-derived skin fibroblasts by the Maxwell RSC simplyRNA Cells Kit and a Maxwell RSC Instrument (Promega). mRNA was enriched using oligo (dT) beads and rRNA removed using the Illumina Ribo-Zero kit.

(124) A phage displaying an Aβ-interacting peptide mitigates neurotoxicity and prevents Aβ-driven gene expression changesFront Mol NeurosciDecember 10, 2025Laura Maria De Plano, Luigi Chiricosta, Simone D'Angiolini, Alessandra Saitta, Alessandra Trainito, Serena Silvestro, Sabrina Conoci, Salvatore Oddo, Antonella Caccamoof 12CIII1. Following treatment, cell pellets were collected, and total RNA was extracted using the Maxwell® RSC instrument according to the manufacturer’s instructions for the Maxwell® RSC simplyRNA Cells Kit (Promega, Madison,

(125) Replicon-based genome-wide CRISPR knockout screening for the identification of host factors involved in viral replicationNat CommunDecember 10, 2025Karen W. Cheng, Madhura Bhave, Andrew L. Markhard, Duo Peng, Karan D. Bhatt, Katherine A. Travisano, Josette V. Medicielo, Astrid Anaya, Sanae Lembirik, Leila Njoya, et al.Maxwell RSC Viral Total Nucleic Acid Purification Kit (Promega, AS1330) and the automated Maxwell RSC extractor (Promega, AS4500). Briefly, 200 µL of TRIzol LS-treated sample were added to 200 µL of the kit’s lysis buffer and vortexed

(126) Induction of immune education in type 1 diabetes through controlled allogeneic islet rejection at onset: a monocentric open-label pilot studyEClinicalMedicineDecember 4, 2025Lorenzo Piemonti, Andrea Mario Bolla, Amelia Caretto, Raffaella Melzi, Alessia Mercalli, Valeria Sordi, Paolo Monti, Paola Magistretti, Vito Lampasona, Ilaria Marzinotto, et al.12, 18 months; and 2, 3, 4, 5 years) using the Maxwell® RSC miRNA from Plasma and Serum kit with the Maxwell® RSC Instrument (Promega), according to manufacturer's instructions. All serum miRNAs underwent universal reverse transcription

(127) Soil phosphate availability drives shifts between arbuscular mycorrhizal and ectomycorrhizal fungi in the dual mycorrhizal plant Quercus serrataNew PhytologistDecember 1, 2025Tatsuhiro Ezawa, Chika Mizukami, Anjar Cahyaningtyas, Mana Mukai, Kanehiro KitayamaMulti‐Beads Shocker (Yasui Kikai), and DNA was extracted and purified from c. 100 mg FW of ground sample by Maxwell RSC Instrument using Maxwell RSC PureFood GMO and Authentication Kit (Promega, Tokyo, Japan) according to the manufacturer's

(128) Infection Dynamics and Host Biomarker Identification for Spotty Liver Disease in ChickensVet SciNovember 29, 2025Helen James, Emily Gan, Robert J. Moore, Daniel M. Andrews, Thi Thu Hao Vanwith C. hepaticus-specific primers as described by Van et al. 2017 [24]. DNA was extracted using the Maxwell® RSC instrument with the Maxwell® RSC PureFood GMO and Authentication Kit (Promega, Madison, WI, USA), following the

(129) Efficacy of nutraceutical supplements containing Passiflora incarnata L., Withania somnifera (L.) Dunal and Taraxacum officinale (L.) weber ex F.H.Wigg. on markers of inflammation, oxidative stress and gut microbiota in senior dogsFrontiers in Veterinary ScienceNovember 27, 2025Roberto Ciarcia, Consiglia Longobardi, Valeria Iervolino, Tommaso Manenti, Francesco Ferrucci, Iolanda Veneruso, Valeria D’Argenio, Antonio Rubino, Alessandra Pelagalli, Pietro Lombardi, et al.h, frozen at −80 °C until analysis. Genomic DNAs were obtained using the RSC Blood DNA kit and the Maxwell RSC instrument (both from Promega, Madison, WI, USA), as previously reported (26). Two blank/negative samples were

(130) NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasmsNature CommunicationsNovember 26, 2025Ruth-Miriam Koerber, Calvin Krollmann, Kevin Cieslak, Elisabeth Tregel, Maria L. Saenz, Tim H. Brümmendorf, Steffen Koschmieder, Martin Griesshammer, Ines Gütgemann, Conny K. Baldauf, et al.(IBL). Quantitative RT–PCR RNA was extracted from cells with the Maxwell RSC simplyRNA Cells Kit (Promega) on a Maxwell RSC instrument and mRNA reverse transcribed with the RevertAid First Strand cDNA Synthesis Kit (Thermo Fisher Scientific).

(131) The host range of generalist and specialist phages in capsule-diverse Klebsiella hosts is driven by the evolvability of receptor-binding proteinsPLOS BiologyNovember 26, 2025Celia Ferriol-González, Pilar Domingo-Calap5-Kit (Zymo) for the passages and using Maxwell PureFood GMO and Authentication Kit (Promega) with Maxwell RSC Instrument (Promega) for single plaques. Sequencing libraries were prepared using the Illumina Nextera XT DNA kit

(132) Genomic landscape and molecular subtypes of primary central nervous system lymphomaBlood Cancer JournalNovember 26, 2025Shengjie Li, Danhui Li, Zuguang Xia, Jianing Wu, Jun Ren, Yingzhu Li, Jiazhen Cao, Ying Sun, Chengxun Li, Wenjun Cao, et al.DNA (gDNA) was extracted via the Maxwell RSC Blood DNA Kit (AS1400, Promega) on a Maxwell RSC system (AS4500, Promega) following the manufacturer’s instructions. For FFPE tissue, total gDNA was extracted via the

(133) Alteration of miR-21 and miR-24 expression: biomarker for early detection of synchronous metastases in colorectal cancer: a cross-sectional study in IndonesiaIntestinal ResearchNovember 19, 2025Yudith Annisa Ayu Rezkitha, Amal Arifi Hidayat, Irine Normalina, Ricky Indra Alfaray, Maria Inge Lusida, Takashi Matsumoto, Yoshio Yamaoka, Muhammad MiftahussururMaxwell RSC miRNA Tissue Kit (Promega, Madison, WI, USA; AS1460) and a Maxwell RSC instrument (Promega, AS4500), following the manufacturer’s protocol. The RNA quantity was measured, and the samples were stored

(134) Olutasidenib for mutated IDH1 acute myeloid leukemia: final five-year results from the phase 2 pivotal cohortJournal of Hematology & OncologyNovember 14, 2025Jorge Cortes, Antonio Curti, Pierre Fenaux, Brian A. Jonas, Jürgen Krauter, Pau Montesinos, Christian Récher, David C. Taussig, Eunice S. Wang, Justin Watts, et al.in PAXGene® tubes. Blood genomic DNA (gDNA) was isolated using the Maxwell® RSC Blood DNA Kit on the Maxwell® RSC Instrument (Promega, Madison, WI, USA), according to the manufacturer’s instructions. The yield of gDNA was assessed

(135) Gut bacteria metabolize natural and synthetic steroid hormones via the reductive OsrABC pathwayCell Host & MicrobeNovember 12, 2025Christian Jacoby, Kaylie Scorza, Lia Ecker, Paola Nol Nol Bernardino, Alexander S. Little, Mary McMillin, Ramanujam Ramaswamy, Anitha Sundararajan, Ashley M. Sidebottom, Huaiying Lin, et al.processing. Cell pellets were thawed and total RNA from biological replicates were extracted using the Maxwell RSC instrument (Promega). Extracted RNA was quantified using Qubit, and integrity was measured using TapeStation (Agilent

(136) Identification of poultry commensal bacteria with the ability to inhibit the growth of Salmonella enterica serovar Typhimurium in co-cultureBMC MicrobiologyNovember 12, 2025Zhixuan Feng, Valérie Dagenais, Valérie Leclerc, Clara Pigozzo, Jennifer Ronholmincubation period. The suspension was then transferred into the DNA extraction cartridge and placed in the Maxwell® RSC instrument (Promega, USA). The DNA was extracted using the pre-programmed “Blood DNA extraction” program. The DNA

(137) Germline Mutations in DNA Repair Genes in Patients with Pancreatic Neuroendocrine Neoplasms: Diagnostic and Therapeutic ImplicationsCurrent OncologyNovember 10, 2025Beata Jurecka-Lubieniecka, Małgorzata Ros-Mazurczyk, Aleksandra Sygula, Alexander J. Cortez, Marcela Krzempek, Anna B. Tuleja, Agnieszka Kotecka-Blicharz, Marta Cieslicka, Malgorzata Oczko-Wojciechowska, Daria Handkiewicz-JunakVacutainer® tubes. Genomic DNA was isolated from leukocytes using the Maxwell® RSC Blood DNA Kit on the Maxwell® RSC Instrument (Promega GmbH, Madison, WI, USA). DNA concentration and quality were assessed using the Qubit® 2.0 fluorometer

(138) Altered expression of autophagy-related molecules and β-catenin in different subtypes of thyroid cancer: co-localization in intranuclear cytoplasmic inclusionsEndocrine JournalNovember 4, 2025Yerkezhan Sailaubekova, Katsuya Matsuda, Yuko Akazawa, Hirokazu Kurohama, Yuki Matsuoka, Keiji Suzuki, Adiya Kerimbayeva, Hisayoshi Kondo, Van Phu Thang Nguyen, Thi Ngoc Anh Nguyen, et al.56°C. DNA extraction was performed using a Maxwell RSC DNA FFPE kit (Promega, Madison, WI, USA) and Maxwell RSC instrument (Promega), according to the manufacturer’s protocols. The concentration of double-strand DNA was quantified

(139) Oxford Nanopore Technologies [ONT] Sequencing: Clinical Validation in Genetically Heterogeneous DisordersGenes (Basel)November 3, 2025Mario Urtis, Chiara Paganini, Viviana Vilardo, Antonio Tescari, Samantha Minetto, Claudia Cavaliere, Andrea Pilotto, Carmela Giorgianni, Alessia Cattaneo, Marilena Tagliani, et al.Supplementary Table S1. 2.4. DNA Isolation DNA previously extracted from peripheral blood samples by Maxwell RSC Instrument (Promega, Madison, WI, USA) using Maxwell CSC Blood DNA Kit (Promega) according to the manufacturer’s

(140) TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast CancerAdvanced ScienceNovember 1, 2025Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, et al.silenced cells using the Maxwell RSC miRNA Tissue kit (AS1460, Promega) with the Maxwell RSC Instrument (AS4500, Promega). cDNA preparation was performed using the i‐Script reverse transcription Supermix Real Time

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