Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(121) Accurate genotyping of three major respiratory bacterial pathogens with ONT R10.4.1 long-read sequencingGenome ResearchAugust 1, 2025Nora Zidane, Carla Rodrigues, Valérie Bouchez, Martin Rethoret-Pasty, Virginie Passet, Sylvain Brisse, Chiara Crestanistandardized conditions, as previously described (Bouchez et al. 2018). DNA extraction was performed on a Maxwell RSC instrument (Promega) with the Maxwell RSC Blood DNA Kit (Promega) following the manufacturer's instructions. Library

(122) Identifying Genetic Variations in emm89 Streptococcus pyogenes Associated with Severe Invasive InfectionsElifeJuly 24, 2025Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara, et al.mg/ml RNase A (Promega, Madison, WI, USA). Next, genomic DNA was extracted from each lysate using a Maxwell RSC instrument (Promega), according to the manufacturer’s instructions, and 250 bp paired-end libraries were then generated

(123) Identifying genetic variations in emm89 Streptococcus pyogenes associated with severe invasive infectionsElifeJuly 24, 2025Masayuki Ono, Masaya Yamaguchi, Daisuke Motooka, Yujiro Hirose, Kotaro Higashi, Tomoko Sumitomo, Tohru Miyoshi-Akiyama, Rumi Okuno, Takahiro Yamaguchi, Ryuji Kawahara, et al.mg/ml RNase A (Promega, Madison, WI, USA). Next, genomic DNA was extracted from each lysate using a Maxwell RSC instrument (Promega), according to the manufacturer’s instructions, and 250 bp paired-end libraries were then generated

(124) FGFR4 p.Gly388Arg polymorphism in PBMCs of LAM patients: findings of a pilot studyFrontiers in MedicineJuly 24, 2025Sinem Koc-Gunel, Amy L. Ryan, Melanie Winter, Thomas O. F. Wagnerplatelets and Ficoll. DNA extraction and quantification Genomic DNA was (13) extracted using the Maxwell® RSC Instrument (Promega Corporation, Madison, Wisconsin, United States) with the Maxwell® RSC FFPE Plus DNA Kit (Promega Corporation

(125) A predictive endocrine resistance index accurately stratifies luminal breast cancer treatment responders and nonrespondersJ Clin InvestJuly 24, 2025Guokun Zhang, Vindi Jurinovic, Stephan Bartels, Matthias Christgen, Henriette Christgen, Leonie Donata Kandt, Lidiya Mishieva, Hua Ni, Mieke Raap, Janin Klein, et al.microdissection to enrich for invasive tumor cells, DNA was extracted using the Maxwell RSC DNA FFPE kit on a Maxwell RSC instrument (Promega), and quality control tested (post-QC, discovery cohort, n = 362; validation cohort 1, n =

(126) Site‐Specific Mutations on KRAS , NRAS , and BRAF Corelate With the Frequency of ctDNA in Colorectal CancerCancer Rep (Hoboken)July 23, 2025Fumihiro Yoshimura, Yoichiro Yoshida, Teppei Yamada, Keita Tanaka, Takaomi Hayashi, Hideki Shimaoka, Ryohei Sakamoto, Naoya Aisu, Gumpei Yoshimatsu, Suguru Hasegawafrom 1.0 mL plasma using the Maxwell RSC cfDNA plasma kit (Promega Corporation, Madison, WI, USA) and Maxwell RSC Instrument (Promega Corporation, Madison, USA) following the manufacturer's protocol, as described previously [19]. 2.4

(127) Analysis of the Microbiota of Milk from Holstein-Friesian Dairy Cows Fed a Microbial SupplementAnimals (Basel)July 18, 2025Bronwyn E. Campbell, Mohammad Mahmudul Hassan, Timothy Olchowy, Shahab Ranjbar, Martin Soust, Orlando Ramirez-Garzon, Rafat Al Jassim, Robert J. Moore, John I. Alawnehbuffers but no sample, were loaded into the cartridges of the kit and extracted automatically on a Maxwell® RSC instrument (Promega, Madison, WI, USA). The quality and quantity of DNA were assessed using a NanoDrop™ spectrophotometer

(128) Altered expression of autophagy-related molecules and β-catenin in different subtypes of thyroid cancer: co-localization in intranuclear cytoplasmic inclusionsEndocr JJuly 17, 2025Yerkezhan Sailaubekova, Katsuya Matsuda, Yuko Akazawa, Hirokazu Kurohama, Yuki Matsuoka, Keiji Suzuki, Adiya Kerimbayeva, Hisayoshi Kondo, Van Phu Thang Nguyen, Thi Ngoc Anh Nguyen, et al.56°C. DNA extraction was performed using a Maxwell RSC DNA FFPE kit (Promega, Madison, WI, USA) and Maxwell RSC instrument (Promega), according to the manufacturer’s protocols. The concentration of double-strand DNA was quantified

(129) Prevotella as the main driver for the association between dairy farming and human gut microbiome compositionFrontiers in MicrobiomesJuly 9, 2025Tryntsje Cuperus, Jolanda Kool, David Boverhoff, Kees van der Ark, Marieke Opsteegh, Susana Fuentesof S.T.A.R. buffer following the same procedure. Pooled faecal lysates were then transferred to the Maxwell RSC Instrument (Promega Benelux BV) for further purification steps. Eluted sample was cleaned-up using the OneStep PCR Inhibitor Removal Kit

(130) Loss of PLA2G4E compromises synaptic structure and cognitive outcomes in miceLife Sci AllianceJuly 9, 2025Sara Badesso, Marta Perez-Gonzalez, Sara Exposito, Maria Espelosin, Clara Cambria, Laura D'Andrea, Gabriele Imperato, Pedram Moeini, Africa Vales, Gloria Gonzalez-Aseguinolaza, et al.following the manufacturer’s protocol. Thanks to magnetic beads supplied in the Maxwell RSC Cartridge, Maxwell RSC Instrument performed RNA extraction and DNase I treatment resulting in 25-50 μl RNA-containing solution that was

(131) Discovery of glycerol phosphate and an immunogenic glycan motif in rhamnose-rich polysaccharides of Streptococcus uberisVet ResJuly 7, 2025Yao Shi, Göran Widmalm, Natalia Korotkova, Adrian Molenaar, Mark A. Holmes, Scott McDougall, Jetta J. E. Bijlsma, Nina M. van Sorge, Lindert Benedictus120 rpm. Whole-genome sequencing and assembly Genomic DNA of S. uberis 233 was isolated using the Maxwell® RSC Instrument (Promega) after overnight growth in THY broth. DNA was quantified by Qubit Fluorometer (Invitrogen).

(132) Examination of the enrichment of neuronal extracellular vesicles from cell conditioned media and human plasma using an anti-NCAM immunocapture bead approachBMC MethodsJuly 1, 2025Mary E. W. Collier, Natalie Allcock, Nicolas Sylvius, Jordan Cassidy, Flaviano Giorginiwas isolated from the EV lysates using the Maxwell RSC miRNA from plasma and serum kit (Promega) on a Maxwell RSC instrument (Promega) according to the manufacturer’s instructions and eluted in 40 µl of nuclease free water. RNA

(133) Efficient cell-free translation from diverse human cell typesJournal of Biological ChemistryJuly 1, 2025Jana Ziegelmüller, Nikolaos Kouvelas, Nino Schwaller, Priyanka Thambythurai, Alexander M. Hofer, Oliver Mühlemann, Evangelos D. Karousisextraction RNA extraction for RT-qPCR analysis was carried out using the Maxwell RSC Instrument (Promega, Cat# AS4500) and the Maxwell RSC simplyRNA Cells Kit (Promega, Cat# AS1390), following the manufacturer’s protocol.

(134) Comparative transcriptomics of salinomycin molecular toxicity in chicken and turkeySci RepJuly 1, 2025İlksen Berfin Ekinci, Anna Sławińska, Kacper Żukowski, Małgorzata Olejniksummarized in Fig. 1. RNA isolation The total RNA was isolated from the liver and heart samples using the Maxwell® RSC instrument (Promega, USA). The tissue size was 100 mg, and the extraction was performed with Maxwell® RSC simplyRNA Tissue Kit

(135) Comparative Evaluation of the Serological Methods and the Molecular Genetics Techniques for the Diagnosis of Encephalitozoon cuniculi in Rabbits (Oryctolagus cuniculus)MicroorganismsJune 25, 2025Anca-Alexandra Doboși, Anamaria Ioana Paștiu, Sanda Andrei, Dana Liana Pustasamples, where the enzymatic digestion of the samples was performed with proteinase K at 56 °C. The Maxwell® RSC Instrument (Promega, Madison, WI, USA) for automatic extractions was required for this process and the final products

(136) Identification of diagnostic DNA methylation markers in the blood of Japanese Alzheimer's disease patients using methylation capture sequencingClin EpigeneticsJune 20, 2025Risa Mitsumori, Kayoko Sawamura, Kimi Yamakoshi, Akinori Nakamura, Yutaka Arahata, Shumpei Niida, Daichi Shigemizu, Kouichi Ozaki, Nobuyoshi Shimodaobtained from the NCGG biobank. Preparation of gDNA gDNA was extracted from peripheral blood using a Maxwell RSC Instrument (Promega, USA) with the Maxwell RSC Buffy Coat DNA Kit (Promega, USA). The quantity of gDNA was measured

(137) Sustainable water reuse in food production: risks of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and antimicrobial resistance gene release from tertiary-treated reclaimed waterFrontiers in MicrobiologyJune 19, 2025Pilar Truchado, Márcia Oliveira, Rebeca Cordero-García, Manuel Abellán Soler, Amador Rancaño, Francisca García, Avelino Álvarez-Ordóñez, Ana Allendegenomic DNA extraction. Genomic DNA extraction from wastewater concentrates was performed using the Maxwell® RSC Instrument (Promega) and the Maxwell RSC Pure Food GMO and Authentication Kit (Promega), following the Maxwell

(138) Marked reduction of SARS-CoV-2 infection and improved recovery following supplementation with a probiotic mix of four strains and two strains of Bifidobacterium breve in hamstersApplied and Environmental MicrobiologyJune 18, 2025Edgar Torres-Maravilla, Marine Wasniewski, Aurélie Wauquier, Alexandre Servat, Evelyne Picard-Meyer, Elodie Monchatre-Leroy, Sandrine Auger, Sophie Holowacz, Franck Boué, Philippe Langella, et al.DNA was extracted from 100 mg of fecal sample using the Maxwell RSC Fecal Microbiome DNA Kit on the Maxwell RSC Instrument according to the provided user guidelines (Promega). The concentration and quality of extracted DNA

(139) Pollen parent affects rutin content of seeds of buckwheat (Fagopyrum esculentum)Breeding ScienceJune 18, 2025Shiori Otsuka, Takashi Hara, Koji Ishiguro, Kenichi Matsushima, Yasuo Yasui, Katsuhiro Matsuiwith a mortar and pestle. Total RNA was extracted from the seeds with a Maxwell RSC Plant RNA Kit in a Maxwell RSC Instrument (Promega) according to the manufacturer’s protocol. A Next Generation Sequencing library was constructed

(140) Targeting inflammatory macrophages with hyaluronan tetrasaccharide: effects on fibroblast collagen degradation and synthesisFront ImmunolJune 5, 2025Eiko Uno, Florence Kim, Mihoko Yoshino, Yasunari Sato, Masao Hashimoto, Kenji Watanabe, Yoichi Mizukami, Jun MutoCambridge, UK). 2.7 Real-time qPCR analysis Total RNA was extracted from macrophages and NHDF with the Maxwell® RSC Instrument (Promega, Madison, WI, USA) following the manufacturer’s guidelines. The complementary DNA (cDNA) library

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