Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(121) Marked reduction of SARS-CoV-2 infection and improved recovery following supplementation with a probiotic mix of four strains and two strains of Bifidobacterium breve in hamstersApplied and Environmental MicrobiologyJune 18, 2025Edgar Torres-Maravilla, Marine Wasniewski, Aurélie Wauquier, Alexandre Servat, Evelyne Picard-Meyer, Elodie Monchatre-Leroy, Sandrine Auger, Sophie Holowacz, Franck Boué, Philippe Langella, et al.DNA was extracted from 100 mg of fecal sample using the Maxwell RSC Fecal Microbiome DNA Kit on the Maxwell RSC Instrument according to the provided user guidelines (Promega). The concentration and quality of extracted DNA

(122) Targeting inflammatory macrophages with hyaluronan tetrasaccharide: effects on fibroblast collagen degradation and synthesisFront ImmunolJune 5, 2025Eiko Uno, Florence Kim, Mihoko Yoshino, Yasunari Sato, Masao Hashimoto, Kenji Watanabe, Yoichi Mizukami, Jun MutoCambridge, UK). 2.7 Real-time qPCR analysis Total RNA was extracted from macrophages and NHDF with the Maxwell® RSC Instrument (Promega, Madison, WI, USA) following the manufacturer’s guidelines. The complementary DNA (cDNA) library

(123) Visualizing fatigue mechanisms in non-communicable diseases: an integrative approach with multi-omics and machine learningBMC Med Inform Decis MakJune 3, 2025Yusuke Kobayashi, Naoki Fujiwara, Yuki Murakami, Shoichi Ishida, Sho Kinguchi, Tatsuya Haze, Kengo Azushima, Akira Fujiwara, Hiromichi Wakui, Masayoshi Sakakura, et al.gene sequencing to characterize microbial communities. Extraction of DNA was performed using a Promega Maxwell RSC Instrument (Promega Corporation, Madison, WI, USA), and the V3–V4 regions of the 16S rRNA gene were amplified using

(124) Low-grade oncocytic tumor of the kidney-a clinical, pathological, and next generation sequencing-based study of 20 tumorsPathol Oncol ResJune 2, 2025Alex Jenei, Boglárka Pósfai, Borbála Dénes, Áron Somorácz, Gertrud Forika, Attila Fintha, Zsófia Mészáros, Noémi Kránitz, Tamás Micsik, Kornélia Veronika Eizler, et al.sequencing was carried out. Nucleic acid isolation was performed using Maxwell RSC DNA/RNA FFPE Kit on Maxwell RSC Instrument (Promega) according to the manufacturer’s instruction. DNA and RNA concentrations were measured using

(125) Wastewater surveillance of SARS-CoV-2 from aircraft to citywide monitoringNat CommunJune 2, 2025Mariel Perez-Zabaleta, Carlo Berg, Neus Latorre-Margalef, Isaac Owusu-Agyeman, Ayda Kiyar, Helene Botnen, Caroline Schönning, Luisa W. Hugerth, Zeynep Ceteciogluloaded into a cartridge provided by the kit. Afterwards, total nucleic acid (TNA) was extracted using Maxwell RSC Instrument (Promega Biotech AB, Sweden) and Maxwell RSC Pure Food GMO programme was selected. The elution volume

(126) Cracking rare disorders: a new minimally invasive RNA-seq protocolNPJ Genom MedMay 28, 2025Laurenz De Cock, Erika D'haenens, Lies Vantomme, Lynn Backers, Aude Beyens, Kathleen Bm Claes, Griet De Clercq, Robin de Putter, Candy Kumps, Nika Schuermans, et al.kb (as described earlier44). RNA extraction RNA was extracted using the Maxwell® RSC instrument (AS4500, Promega). Depending from which tissue RNA was isolated a different extraction kit was used: (1) PBMCs,

(127) A multi-omics integration approach relying on circulating factors does not discern subtypes of childhood type 1 diabetesCommun Med (Lond)May 27, 2025Valentina Codazzi, Nicola Baldoni, Giulia M. Scotti, Anna Giovenzana, Andrea Rigamonti, Giulio Frontino, Eugenia Bezzecchi, Camillo Bechi Genzano, Alessandra Mandelli, Debora Carnovale, et al.from whole blood was conducted on a subset of 90 subjects using the Maxwell® RSC Blood DNA Kit and the Maxwell® RSC Instrument from Promega. For each participant, the Type 1 Diabetes Genetic Risk Score 2 (T1D GRS-2) was calculated.

(128) The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological featuresMolecular OncologyMay 26, 2025Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulanynext‐generation sequencing Genomic DNA was extracted using the Maxwell® RSC DNA FFPE Kit and the Maxwell® RSC Blood Kit, and the Maxwell® RSC instrument (Promega, Madison, WI, USA) according to the manufacturer's instructions. Targeted multigen mutation

(129) Microevolution and genomic epidemiology of the diphtheria-causing zoonotic pathogen Corynebacterium ulceransNat CommunMay 24, 2025Chiara Crestani, Virginie Passet, Martin Rethoret-Pasty, Nora Zidane, Sylvie Brémont, Edgar Badell, Alexis Criscuolo, Sylvain Brisseprotocol described by the manufacturer38. DNA extraction for Oxford Nanopore sequencing was performed on a Maxwell RSC Instrument (Promega, Madison, USA) with the Maxwell RSC Blood DNA Kit (Promega, Madison, Wisconsin, USA) following

(130) Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activityAngiogenesisMay 23, 2025Sarah E. J. Chambers, Jasenka Guduric-Fuchs, Edoardo Pedrini, Pietro M. Bertelli, Chutima Charoensuk, Elisa Peixoto, Varun Pathak, Hamza I. Alhamdan, Ruoxiao Xie, Anna Krasnodembskaya, et al.barrier. Real-time qRT-qPCR Total RNA was isolated using the Maxwell RSC simplyRNA Cells Kit (Promega) and a Maxwell RSC instrument (Promega) following the manufacturer’s instructions. RNA quantity and purity were assessed using the

(131) TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysisFront ImmunolMay 19, 2025Miguel Chirivi, Ursula Abou-Rjeileh, Madison Myers, Jair Parales-Giron, Lynn Worden, Adam L. Lock, G. Andres Contrerasgenomic DNA, 5 µL of DNase I (Promega) was added. Automated extraction of RNA was carried out using the Maxwell® RSC instrument (Promega Corp.). RNA was flash-frozen in LN2, stored at -80°C, and the concentration and integrity of

(132) Blood collection tube and RNA purification method recommendations for extracellular RNA transcriptome profilingNat CommunMay 15, 2025The exRNAQC Consortium(Promega, AX5740 and AS1680) in combination with the Maxwell RSC Instrument (Maxwell method; Promega, AS4500), and MagNA Pure 24 Total NA Isolation Kit (Roche, 07658036001) in combination with the MagNA Pure 24

(133) Presence of Potentially Infectious Human Enteric Viruses and Antibiotic Resistance Genes in Mussels from the Campania Region, Italy: Implications for Consumer's SafetyFood Environ VirolMay 15, 2025Iolanda Venuti, Enric Cuevas-Ferrando, Irene Falcó, Inés Girón-Guzmán, Marina Ceruso, Tiziana Pepe, Gloria Sánchez– 80 °C (Fig. 2). Nucleic acid extraction from mussel concentrates (300 μL) was performed using the Maxwell® RSC Instrument (Promega, Spain) with the Maxwell RSC Pure Food GMO and authentication kit (Promega), utilizing the

(134) Novel cross-feeding human gut microbes metabolizing tryptophan to indole-3-propionateGut MicrobesMay 8, 2025Janina N. Zünd, Denisa Mujezinovic, Markus Reichlin, Serafina Plüss, Marina Caflisch, Serina Robinson, Christophe Lacroix, Benoit Puginrcf for 5 min. The DNA from fecal cultures incubated with tryptophan was further purified using the Maxwell® RSC instrument and the Maxwell® RSC PureFood GMO and Authentication Kit (Promega). The DNA from fecal cultures incubated

(135) Clonal hematopoiesis in patients with cancer and its association with risk of thrombosis and prognosis of diseaseResearch and Practice in Thrombosis and HaemostasisMay 8, 2025Cornelia Englisch, Roland Jäger, Jasmina Gassner, Alice Assinger, Matthias Preusser, Peter Valent, Ingrid Pabinger, Cihan Aypreparation DNA was isolated from patients’ peripheral blood samples using the Maxwell RSC Blood DNA Kit on a Maxwell RSC Instrument (Promega). Routine parameters including hemoglobin, platelet and leucocyte counts, red cell distribution width

(136) Identification and characterization of tertiary lymphoid structures in brain metastasesActa Neuropathol CommunMay 3, 2025Sadaf S. Mughal, Yvonne Reiss, Jörg Felsberg, Lasse Meyer, Jadranka Macas, Silja Schlue, Tatjana Starzetz, Karl Köhrer, Tanja Fehm, Volkmar Müller, et al.of ≥ 80% were used for RNA extraction. RNA was extracted using the Maxwell® RSC RNA FFPE kit and the Maxwell® RSC instrument (Promega, Mannheim, Germany) as recommended by the manufacturer. RNA sequencing Total RNA samples

(137) RNA sequencing driven diagnosis expands the phenotypic spectrum of NBAS deficiencyMolecular Genetics and MetabolismMay 1, 2025Sarah Silverstein, Thomas Cassini, Jiayu Fu, Barbara Pusey, Ellen Macnamara, F Graeme Frost, Charlotte Williams, Yan Huang, Cynthia J. Tifft, Undiagnosed Diseases Network, et al.(A1285901, Gibco/ThermoFisher), washed with PBS and pelleted. Total RNA was extracted using Maxwell® RSC (AS4500, Promega) and Maxwell® RSC simplyRNA Cells Kit (AS1390, Promega) following manufacturer’s instructions.

(138) Identifying Rare Germline Variants Associated with Metastatic Prostate Cancer Through an Extreme Phenotype StudymedRxivApril 30, 2025Yen-Yi Lin, Hamideh Sharifi Sharifi Noghabi, Stanislav Volik, Robert Bell, Funda Sar, Anne Haegert Haegert, Hee Chul Chung, Ladan Fazli, Htoo Zarni Zarni Oo, Mads Dauggard, et al.tumour and matched distant benign tissues was extracted using the Maxwell RSC DNA FFPE kit and with the Maxwell RSC instrument (Promega) according to the manufacturer’s instructions. The quality and quantity of the extracted DNA

(139) Hypericin Suppresses SARS-CoV-2 Replication and Synergizes with Antivirals via Dual Targeting of RdRp and 3CLproMicroorganismsApril 27, 2025Helena da Silva Souza, Jéssica Santa Cruz Carvalho Martins, Thiagos das Chagas Sousa, Saiqa Sardar, Natalia Fintelman-Rodrigues, Lina Silva-Trujillo, Thiago Moreno Lopes e Souza, Marilda Mendonça Siqueira, Jorge Hernandes Fernandes, Aline da Rocha Matoswere collected for viral RNA quantification by real-time RT-PCR. Total RNA was extracted using the Maxwell® RSC Instrument (Promega, Madison, WI, USA), according to the manufacturer’s instructions. Quantitative RT-PCR was performed

(140) Genomic epidemiology of Salmonella Enteritidis human infections in the Netherlands, 2019 to 2023Microb GenomApril 23, 2025Linda E. Chanamé Pinedo, Eelco Franz, Timothy J. Dallman, Claudia E. Coipan, Roxanne Wolthuis, Kees T. Veldman, Lapo Mughini-Gras, Roan Pijnacker, Maaike J.C. van den Beldperformed using either the GenElute Bacterial Genomic DNA kit (Sigma-Aldrich, Inc.) or automated with the Maxwell® RSC Instrument using the cultured cells DNA kit (Promega Corp.), both according to the manufacturers' protocol. Library

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