Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(201) A multi-omics integration approach relying on circulating factors does not discern subtypes of childhood type 1 diabetesCommun Med (Lond)May 27, 2025Valentina Codazzi, Nicola Baldoni, Giulia M. Scotti, Anna Giovenzana, Andrea Rigamonti, Giulio Frontino, Eugenia Bezzecchi, Camillo Bechi Genzano, Alessandra Mandelli, Debora Carnovale, et al.from whole blood was conducted on a subset of 90 subjects using the Maxwell® RSC Blood DNA Kit and the Maxwell® RSC Instrument from Promega. For each participant, the Type 1 Diabetes Genetic Risk Score 2 (T1D GRS-2) was calculated.

(202) The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological featuresMolecular OncologyMay 26, 2025Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulanynext‐generation sequencing Genomic DNA was extracted using the Maxwell® RSC DNA FFPE Kit and the Maxwell® RSC Blood Kit, and the Maxwell® RSC instrument (Promega, Madison, WI, USA) according to the manufacturer's instructions. Targeted multigen mutation

(203) Microevolution and genomic epidemiology of the diphtheria-causing zoonotic pathogen Corynebacterium ulceransNat CommunMay 24, 2025Chiara Crestani, Virginie Passet, Martin Rethoret-Pasty, Nora Zidane, Sylvie Brémont, Edgar Badell, Alexis Criscuolo, Sylvain Brisseprotocol described by the manufacturer38. DNA extraction for Oxford Nanopore sequencing was performed on a Maxwell RSC Instrument (Promega, Madison, USA) with the Maxwell RSC Blood DNA Kit (Promega, Madison, Wisconsin, USA) following

(204) Human endothelial colony forming cells (ECFCs) require endothelial protein C receptor (EPCR) for cell cycle progression and angiogenic activityAngiogenesisMay 23, 2025Sarah E. J. Chambers, Jasenka Guduric-Fuchs, Edoardo Pedrini, Pietro M. Bertelli, Chutima Charoensuk, Elisa Peixoto, Varun Pathak, Hamza I. Alhamdan, Ruoxiao Xie, Anna Krasnodembskaya, et al.barrier. Real-time qRT-qPCR Total RNA was isolated using the Maxwell RSC simplyRNA Cells Kit (Promega) and a Maxwell RSC instrument (Promega) following the manufacturer’s instructions. RNA quantity and purity were assessed using the

(205) TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysisFront ImmunolMay 19, 2025Miguel Chirivi, Ursula Abou-Rjeileh, Madison Myers, Jair Parales-Giron, Lynn Worden, Adam L. Lock, G. Andres Contrerasgenomic DNA, 5 µL of DNase I (Promega) was added. Automated extraction of RNA was carried out using the Maxwell® RSC instrument (Promega Corp.). RNA was flash-frozen in LN2, stored at -80°C, and the concentration and integrity of

(206) Blood collection tube and RNA purification method recommendations for extracellular RNA transcriptome profilingNat CommunMay 15, 2025The exRNAQC Consortium(Promega, AX5740 and AS1680) in combination with the Maxwell RSC Instrument (Maxwell method; Promega, AS4500), and MagNA Pure 24 Total NA Isolation Kit (Roche, 07658036001) in combination with the MagNA Pure 24

(207) Presence of Potentially Infectious Human Enteric Viruses and Antibiotic Resistance Genes in Mussels from the Campania Region, Italy: Implications for Consumer's SafetyFood Environ VirolMay 15, 2025Iolanda Venuti, Enric Cuevas-Ferrando, Irene Falcó, Inés Girón-Guzmán, Marina Ceruso, Tiziana Pepe, Gloria Sánchez– 80 °C (Fig. 2). Nucleic acid extraction from mussel concentrates (300 μL) was performed using the Maxwell® RSC Instrument (Promega, Spain) with the Maxwell RSC Pure Food GMO and authentication kit (Promega), utilizing the

(208) Examination of the enrichment of neuronal extracellular vesicles from cell conditioned media and human plasma using an anti-NCAM immunocapture bead approachbioRxiv : the preprint server for biologyMay 14, 2025Collier MEW, Allcock N, Sylvius N, Cassidy J, Giorgini F.was isolated from the EV lysates using the Maxwell RSC miRNA from plasma and serum kit (Promega) on a Maxwell RSC instrument (Promega) according to the manufacturer’s instructions and eluted in 40 µl of nuclease free water. RNA

(209) Novel cross-feeding human gut microbes metabolizing tryptophan to indole-3-propionateGut MicrobesMay 8, 2025Janina N. Zünd, Denisa Mujezinovic, Markus Reichlin, Serafina Plüss, Marina Caflisch, Serina Robinson, Christophe Lacroix, Benoit Puginrcf for 5 min. The DNA from fecal cultures incubated with tryptophan was further purified using the Maxwell® RSC instrument and the Maxwell® RSC PureFood GMO and Authentication Kit (Promega). The DNA from fecal cultures incubated

(210) Clonal hematopoiesis in patients with cancer and its association with risk of thrombosis and prognosis of diseaseResearch and Practice in Thrombosis and HaemostasisMay 8, 2025Cornelia Englisch, Roland Jäger, Jasmina Gassner, Alice Assinger, Matthias Preusser, Peter Valent, Ingrid Pabinger, Cihan Aypreparation DNA was isolated from patients’ peripheral blood samples using the Maxwell RSC Blood DNA Kit on a Maxwell RSC Instrument (Promega). Routine parameters including hemoglobin, platelet and leucocyte counts, red cell distribution width

(211) Identification and characterization of tertiary lymphoid structures in brain metastasesActa Neuropathol CommunMay 3, 2025Sadaf S. Mughal, Yvonne Reiss, Jörg Felsberg, Lasse Meyer, Jadranka Macas, Silja Schlue, Tatjana Starzetz, Karl Köhrer, Tanja Fehm, Volkmar Müller, et al.of ≥ 80% were used for RNA extraction. RNA was extracted using the Maxwell® RSC RNA FFPE kit and the Maxwell® RSC instrument (Promega, Mannheim, Germany) as recommended by the manufacturer. RNA sequencing Total RNA samples

(212) RNA sequencing driven diagnosis expands the phenotypic spectrum of NBAS deficiencyMolecular Genetics and MetabolismMay 1, 2025Sarah Silverstein, Thomas Cassini, Jiayu Fu, Barbara Pusey, Ellen Macnamara, F Graeme Frost, Charlotte Williams, Yan Huang, Cynthia J. Tifft, Undiagnosed Diseases Network, et al.(A1285901, Gibco/ThermoFisher), washed with PBS and pelleted. Total RNA was extracted using Maxwell® RSC (AS4500, Promega) and Maxwell® RSC simplyRNA Cells Kit (AS1390, Promega) following manufacturer’s instructions.

(213) Identifying Rare Germline Variants Associated with Metastatic Prostate Cancer Through an Extreme Phenotype StudymedRxivApril 30, 2025Yen-Yi Lin, Hamideh Sharifi Sharifi Noghabi, Stanislav Volik, Robert Bell, Funda Sar, Anne Haegert Haegert, Hee Chul Chung, Ladan Fazli, Htoo Zarni Zarni Oo, Mads Dauggard, et al.tumour and matched distant benign tissues was extracted using the Maxwell RSC DNA FFPE kit and with the Maxwell RSC instrument (Promega) according to the manufacturer’s instructions. The quality and quantity of the extracted DNA

(214) Hypericin Suppresses SARS-CoV-2 Replication and Synergizes with Antivirals via Dual Targeting of RdRp and 3CLproMicroorganismsApril 27, 2025Helena da Silva Souza, Jéssica Santa Cruz Carvalho Martins, Thiagos das Chagas Sousa, Saiqa Sardar, Natalia Fintelman-Rodrigues, Lina Silva-Trujillo, Thiago Moreno Lopes e Souza, Marilda Mendonça Siqueira, Jorge Hernandes Fernandes, Aline da Rocha Matoswere collected for viral RNA quantification by real-time RT-PCR. Total RNA was extracted using the Maxwell® RSC Instrument (Promega, Madison, WI, USA), according to the manufacturer’s instructions. Quantitative RT-PCR was performed

(215) Genomic epidemiology of Salmonella Enteritidis human infections in the Netherlands, 2019 to 2023Microb GenomApril 23, 2025Linda E. Chanamé Pinedo, Eelco Franz, Timothy J. Dallman, Claudia E. Coipan, Roxanne Wolthuis, Kees T. Veldman, Lapo Mughini-Gras, Roan Pijnacker, Maaike J.C. van den Beldperformed using either the GenElute Bacterial Genomic DNA kit (Sigma-Aldrich, Inc.) or automated with the Maxwell® RSC Instrument using the cultured cells DNA kit (Promega Corp.), both according to the manufacturers' protocol. Library

(216) Epileptic encephalopathy in a young Bengal cat caused by CAD deficiencySci RepApril 18, 2025Adriana Kaczmarska, Matthias Christen, Francisco Del Caño-Ochoa, Santiago Ramon-Maiques, Ana Cloquell Miro, Angie Rupp, Vidhya Jagannathan, Tosso Leeb, Rodrigo Gutierrez-Quintanainvestigation Genomic DNA was extracted from EDTA blood samples using the Maxwell RSC Whole Blood Kit and the Maxwell RSC instrument (Promega, Dübendorf, Switzerland). An Illumina TruSeq DNA PCR-free library from the affected cat was

(217) Hypoxia-induced Wnt5a-secreting fibroblasts promote colon cancer progressionNat CommunApril 17, 2025Akikazu Harada, Yoshiaki Yasumizu, Takeshi Harada, Katsumi Fumoto, Akira Sato, Natsumi Maehara, Ryota Sada, Shinji Matsumoto, Takashi Nishina, Kiyoshi Takeda, et al.203-15263) or 200 μM CoCl2 (Nacalai Tesque; Cat. 09206-92) for 24 h, and total RNA was isolated using Maxwell RSC instrument with Maxwell RSC simplyRNA cells kit (Promega, Madison, WI, USA; Cat. AS1390). Library preparation was

(218) NTRK1 Gene Fusions Are Frequent in Juvenile XanthogranulomaAm J Surg PatholApril 16, 2025Elisabeth Schlögl, Helga Hürner-Unterberger, Ingrid Simonitsch-Klupp, Gabriele Amann, Jaqueline Blank-Foltin, Barbara Neudert, Lisa Wozelka-Oltjan, Christine Haberler, Georg Ebetsberger-Dachs, Leonhard MüllauerPlus DNA Kit (Promega), whereas RNA was extracted using the Maxwell RSC RNA FFPE Kit (Promega) on a Maxwell RSC instrument (Promega). DNA concentrations were quantified using the Qubit dsDNA HS Assay Kit (Thermo Fisher Scientific)

(219) Transmissibility of a new Plasmodium falciparum 3D7 bank for use in malaria volunteer infection studies evaluating transmission blocking interventionsSci RepApril 16, 2025Sean A. Lynch, Azrin N. Abd-Rahman, Jenny M. Peters, Juanita M. Heunis, Jeremy S.E. Gower, Adam J. Potter, Rebecca Webster, Helen Jennings, Susan Mathison, Nischal Sahai, et al.samples incubated for 30 min at 65 °C. DNA was extracted as per Manufacturer’s instructions using the Maxwell® RSC Instrument (Promega) and eluted into 100 μL elution buffer. qPCR assays were performed as previously described18. Outcomes The

(220) NTRK1 Gene Fusions Are Frequent in Juvenile XanthogranulomaAmerican Journal of Surgical PathologyApril 16, 2025Elisabeth Schlögl, Helga Hürner-Unterberger, Ingrid Simonitsch-Klupp, Gabriele Amann, Jaqueline Blank-Foltin, Barbara Neudert, Lisa Wozelka-Oltjan, Christine Haberler, Georg Ebetsberger-Dachs, Leonhard MüllauerPlus DNA Kit (Promega), whereas RNA was extracted using the Maxwell RSC RNA FFPE Kit (Promega) on a Maxwell RSC instrument (Promega). DNA concentrations were quantified using the Qubit dsDNA HS Assay Kit (Thermo Fisher Scientific)

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