Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(281) A new gene signature for endothelial senescence identifies self-RNA sensing by retinoic acid-inducible gene I as a molecular facilitator of vascular agingAging cellSeptember 1, 2024Guduric-Fuchs J, Pedrini E, Bertelli PM, McDonnell S, Pathak V, McLoughlin K, O'Neill CL, Stitt AW, Medina RJ.was based on an absolute log 2‐fold change >1.0 and p < 0.05. RNA from HRMECs was extracted using the Maxwell® RSC instrument and simplyRNA Cells Kit (Promega). Total RNA samples were sent to Edinburgh Genomics (The University

(282) Comparison of DNA extraction methods for genotyping equine histidine-rich glycoprotein insertion/deletion polymorphisms using oral mucosa swabs and fecesVeterinary and Animal ScienceSeptember 1, 2024Ryo Muko, Yoshinobu Ojima, Hiroshi Matsuda, Yuko Toishi, Masa-aki Oikawa, Taekyun Shin, Hiroaki Sato, Akane TanakaMadison, WI, USA) according to the manufacturer's protocol. The kit is optimized for the use with the Maxwell RSC Instrument (Promega) which enables the automated extraction of nucleic acids. An oral mucosa swab sample was collected

(283) Refinement of prognostication for IDH ‐mutant astrocytomas using DNA methylation‐based classificationBrain PathologySeptember 1, 2024Teresia Kling, Sandra Ferreyra Vega, Medha Suman, Anna Dénes, Anna Lipatnikova, Stina Lagerström, Thomas Olsson Bontell, Asgeir Store Jakola, Helena CarénDNA methylation profiling DNA was isolated from FFPE tumor samples with the Maxwell® FFPE Plus DNA Kit using the Maxwell® RSC Instrument (Promega, Madison, Wisconsin, USA) as indicated by the developers. Extraction of DNA from FF tumor samples

(284) Colorectal adenocarcinoma with clear cell changes: immunohistological and molecular findings in three casesVirchows ArchivSeptember 1, 2024Andreas Gocht, Carsten Heidel, Jutta Kirfel, Rita Vesce, Pamela Lazar-Karsten, Helen Pasternack, Madelaine Melzer, Phillip Hildebrand, Nicole Warkentin, Hendrik Schimmelpenning, et al.acid extractions. Isolation of genomic DNA was performed using the Maxwell RSC DNA FFPE Kit and the Maxwell RSC instrument (Promega, Fitchburg WI, U.S.A.). DNA samples were quantified using the Qubit fluorimeter (Thermo Fisher,

(285) Association of genetic variants with autism spectrum disorder in Japanese children revealed by targeted sequencingFrontiers in GeneticsAugust 30, 2024Yuka Shiota, Tomoaki Nishiyama, Shigeru Yokoyama, Yuko Yoshimura, Chiaki Hasegawa, Sanae Tanaka, Sumie Iwasaki, Mitsuru Kikuchiprocessing Buccal mucosa was collected using a swab. Genomic DNA was extracted from the buccal mucosa using a Maxwell RSC Instrument (Promega, Madison, WI, United States) with the Maxwell RSC Blood DNA Kit (Promega), according to the

(286) Overexpression of CCL-20 and CXCL-8 genes enhances tumor escape and resistance to cemiplimab, a programmed cell death protein-1 (PD-1) inhibitor, in patients with locally advanced and metastatic cutaneous squamous cell carcinomaOncoimmunologyAugust 26, 2024Vincenzo De Falco, Stefania Napolitano, Renato Franco, Federica Zito Marino, Luigi Formisano, Daniela Esposito, Gabriella Suarato, Rossella Napolitano, Alfonso Esposito, Francesco Caraglia, et al.tumor samples and 3 healthy samples was extracted using Maxwell® RSC RNA FFPE Kit (Promega) by using Maxwell RSC Instrument of Promega Corporation according to manufacturers’ standard protocol. Total RNA quantification and quality

(287) Pitfalls When Determining HNA-1 Genotypes and Finding Novel AllelesInternational Journal of Molecular SciencesAugust 22, 2024Kirstine Kløve-Mogensen, Tom Browne, Thure Mors Haunstrup, Rudi Steffensenblood or buccal swabs using the Maxwell RSC Blood DNA Kit or the Maxwell RSC Buccal Swab Kit on the Maxwell RSC instrument according to the manufacturer’s protocol (Promega, Madison, WI, USA). Written and oral informed consent

(288) Case report: Pathology, antimicrobial resistance, and molecular characterization of bovine abortion cases caused by Nocardia farcinica in Korean native cattleFrontiers in Veterinary ScienceAugust 21, 2024Eun-Mi Kim, Chi Sun Yun, You-Chan Bae, Hyunkyoung Lee, Bo-Youn Moon, Kichan Lee, Hye-Young Jeoung, Bok-Kyung Ku, Jongho Kimskeletal muscle, small and large intestines, mesenteric lymph nodes, and endocrine organs) using the Maxwell RSC instrument (Promega, Madison, Wisconsin, United States) with the Maxwell® RSC Blood DNA Kit (Promega) and RSC Viral

(289) Buccal DNA global methylation and cognitive performance in stunted children under five years of ageJ Biomed ResAugust 16, 2024Ahmad Rusdan Handoyo Utomo, Yusnita Yusnita, Siti Maulidya Sari, Octaviani Indrasari Ranakusuma, Sunu Bagaskara, Wening Sari, Yulia Suciati, Anggi Puspa Nur Hidayati, Silviatun Nihayah, Catur Anggono Putro, et al.(Maxwell® RSC Blood DNA Kit, Cat. AS1400, Promega, Madison, WI, USA) with magnetic bead technology (Maxwell® RSC Instrument, Promega). The DNA concentration was quantified using spectrophotometry (Tecan Infinite M200 Pro, Switzerland). Epigenetic

(290) Impact of Nanoplastic Particles on Macrophage Inflammation and Intestinal Health in a Mouse Model of Inflammatory Bowel DiseaseNanomaterials (Basel)August 15, 2024Marlene Schwarzfischer, Tano S. Ruoss, Anna Niechcial, Sung Sik Lee, Marcin Wawrzyniak, Andrea Laimbacher, Kirstin Atrott, Roberto Manzini, Marijn Wilmink, Luise Linzmeier, et al.Isolation, RT-PCR, and Real-Time PCR RNA was extracted using the Maxwell RSC simplyRNA Tissue kit and Maxwell RSC instrument (Promega, Walldorf, Germany), following the manufacturer’s guidelines. RNA concentration was determined

(291) Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustardCell Death & DiseaseAugust 10, 2024Virginia Egea, Karina Lutterberg, Dirk Steinritz, Simone Rothmiller, Konrad Steinestel, Jan Caca, Andreas Nerlich, Helmut Blum, Sarah Reschke, Sajjad Khani, et al.aliquots (0.5 × 106 cells) using the Maxwell® RSC miRNA Tissue Kit (Promega, Madison, WI, USA) on the Maxwell® RSC instrument according to the manufacturer’s instructions. Immediately before library construction, RNA aliquots

(292) Circulating microRNAs as biomarkers for stratifying different phases of liver cancer progression and response to therapyScientific ReportsAugust 9, 2024Lucilla D’Abundo, Cristian Bassi, Elisa Callegari, Farzaneh Moshiri, Paola Guerriero, Angelo Michilli, Fernanda Mora, Andrea Casadei Gardini, Angelo Sangiovanni, Fabio Piscaglia, et al.samples using the Maxwell RSC miRNA Plasma and Serum Kit (Promega Italia, Milano, Italy) in an automated Maxwell RSC Instrument (Promega). Purified RNA was collected in 40 μl of deionized sterile water; hence, each μl contained

(293) In pancreatic cancer patients, chemotherapy reshapes the gene expression profile and antigen receptor repertoire of T lymphocytes and enhances their effector response to tumor-associated antigensFrontiers in ImmunologyAugust 8, 2024Silvia Brugiapaglia, Sara Bulfamante, Claudia Curcio, Maddalena Arigoni, Raffaele Calogero, Lisa Bonello, Elisa Genuardi, Rosella Spadi, Maria Antonietta Satolli, Donata Campra, et al.extraction following the manufacturer’s instructions with Maxwell® RSC simplyRNA Cells Kit compatible with Maxwell® RSC Instrument (Promega, Madison, WI). The concentration of mRNA was evaluated with QuantiFluor® RNA System (Promega,

(294) Iron capture through CD71 drives perinatal and tumor-associated Treg expansionJCI InsightAugust 8, 2024Ilenia Pacella, Alessandra Pinzon Grimaldos, Alessandra Rossi, Gloria Tucci, Marta Zagaglioni, Elena Potenza, Valeria Pinna, Ivano Rotella, Ilenia Cammarata, Valeria Cancila, et al.concentration (5–10 ng/μL) for all samples was used for library preparation. Samples were subjected to robotic (Maxwell RSC Instrument, Promega) PCR amplification, library preparation, and sequencing according to the Illumina 16S metagenomics

(295) Phishing vulnerability compounded by older age, apolipoprotein E e4 genotype, and lower cognitionPNAS NexusAugust 5, 2024Didem Pehlivanoglu, Alayna Shoenfelt, Ziad Hakim, Amber Heemskerk, Jialong Zhen, Mario Mosqueda, Robert C Wilson, Matthew Huentelman, Matthew D Grilli, Gary Turner, et al.completely at room temperature for a minimum of 3 hours. DNA was isolated from the Mitra device using the Maxwell RSC instrument (Promega, Madison, WI, USA) according to the manufacturer's instructions in the customized Product Application

(296) The intron binding protein EMB-4 is an opposite regulator of cold and high temperature tolerance in Caenorhabditis elegansPNAS NexusAugust 5, 2024Akane Ohta, Yuki Sato, Kazuho Isono, Takuma Kajino, Keisuke Tanaka, Teruaki Taji, Atsushi Kuharawas extracted from the crushed worms in the homogenization solution using the RSC Tissue RNA kit and Maxwell RSC instrument (Promega). RNA-seq libraries were prepared using TruSeq RNA sample prep kit v2 (Illumina) according

(297) Lipolysis pathways modulate lipid mediator release and endocannabinoid system signaling in dairy cows’ adipocytesJournal of Animal Science and BiotechnologyAugust 3, 2024Madison N. Myers, Miguel Chirivi, Jeff C. Gandy, Joseph Tam, Maya Zachut, G. Andres Contreras°C. Prior to extraction, samples were thawed on ice. RNA was extracted and purified using the automated Maxwell® RSC Instrument (Promega Corp.) and simplyRNA Cells Kit (Promega Corp.) according to the manufacturer’s instructions.

(298) SMARCB1-deficient sinonasal adenocarcinoma: a rare variant of SWI/SNF-deficient malignancy often misclassified as high-grade non-intestinal-type sinonasal adenocarcinoma or myoepithelial carcinomaVirchows ArchivAugust 1, 2024Alena Skálová, Touraj Taheri, Martina Bradová, Tomáš Vaněček, Alessandro Franchi, David Slouka, Tomáš Kostlivý, Gisele de Rezende, Jaroslav Michálek, Natálie Klubíčková, et al.Oncology 500 Kit (Illumina, San Diego, CA). RNA was extracted using the Maxwell RSC DNA FFPE Kit and the Maxwell RSC Instrument (Promega, Madison, WI) according to the manufacturer’s instructions and quantified using the Qubit HS

(299) α7 nicotinic receptor activation mitigates herpes simplex virus type 1 infection in microglia cellsAntiviral ResearchAugust 1, 2024Shih-Heng Chen, Joanne C. Damborsky, Belinda C. Wilson, Rick D. Fannin, James M. Ward, Kevin E. Gerrish, Bo He, Negin P. Martin, Jerrel L. Yakelselection for 48 hours prior to use. 2.5. RNA analysis Total RNA was extracted from cultures using the Maxwell RSC instrument and Maxwell miRNA Tissue Kit (Promega, Cat. # AS1460) according to the manufacturer's protocol. Reverse

(300) Rapid response to selpercatinib in RET fusion positive pancreatic neuroendocrine carcinoma confirmed by smartwatchnpj Precision OncologyJuly 31, 2024Barbara Deschler-Baier, Markus Krebs, Matthias Kroiss, Manik Chatterjee, Daniel Gundel, Christian Kestler, Alexander Kerscher, Volker Kunzmann, Silke Appenzeller, Katja Maurus, et al.ensure adequate tumor cellularity for analysis. DNA and RNA were extracted from FFPE tissue using a Maxwell®RSC instrument (Promega GmbH, Walldorf, Germany) according to standard protocols. Genomic profiling was performed using

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