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Automated DNA/RNA Purification Sample Preparation Workstations
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
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Citations:
(849)
Figures:
(1)
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Promega for
Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Molecular Weight
~85kDa
UV Lamp
Avg. lifetime approximately 6,000 hrs
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (849)
(1)
Can GM soybean be reliably quantified after screening? A risk-based approach for optimizing GMO testing workflow
GM Crops Food
December 31, 2026
Davide La Rocca, Katia Spinella, Pietro Franceschi, Daniela Verginelli, Sara Ciuffa, Marisa Misto, Cinzia Quarchioni, Cristiana Fusco, Stefania Peddis, Pamela Bonini,
et al.
DNA Estractor FAST (©Generon S.p.A, Italy) and later with the RSC PureFood GMO by using an extractor
Maxwell®RSC Instrument
(
Promega
Madison, WI, USA), according to the manufacturer’s instructions. As a test portion, 2 g of
(2)
High-throughput analyses of Phocaeicola vulgatus reveal fitness determinants for gut colonization and during colitis
Gut Microbes
December 31, 2026
Nazik M. Elmekki, Michael J. Coyne, Katia Flores, Leonor García-Bayona, Laurie E. Comstock
Family Institute Microbiome
Metagenomics
Facility (DFI-MMF). Following nucleic acid recovery using a
Maxwell RSC instrument
(
Promega Corporation
, Madison, WI), DNAse treatment and elution, the samples were quantified using Qubit
(3)
Multiplex gene editing suppresses random integration of hepatitis B virus DNA in chronically infected liver
Mol Ther Nucleic Acids
June 16, 2026
Samuel Slattery, Wenwen Huo, Amena Arif, Jennifer Gordon, Ryo Takeuchi
incubated at 80°C for 30 min prior to loading into the Maxwell RSC blood DNA cartridge and ran on the
Maxwell RSC instrument
. Genomic DNA was extracted from 293FT cells using a
Maxwell RSC Cultured Cells DNA Kit
(
Promega
) according
(4)
Cuproptosis inducers mediate cold lethality via SLCR-46.1 in C. elegans
Nat Commun
May 27, 2026
Serina Yamashiro, Satomi Mizuno, Haruka Motomura, Aidan T. Pezacki, Yukina Mori, Christopher J. Chang, Akane Ohta, Atsushi Kuhara
using the Maxwell RSC Simply RNA Tissue Kit (
Promega
;
AS1340
) and the
Maxwell RSC Instrument
(
Promega
;
AS4500
), following the manufacturer’s instructions.
Sequencing
libraries were prepared with the TruSeq Stranded
(5)
Circulating Tumor DNA and microRNA–Based Liquid Biopsy for Longitudinal Treatment Monitoring and Recurrence Prediction in Pediatric Sarcomas: A Prospective Cohort Study
Oncology Research
May 21, 2026
Maher Kurdi, Amber Hassan, Bashar Reda, Anas Nooh, Mohammed Alsobaie, Alaa Alkhotani, Dahlia S. Mirdad, Majid Almansouri, Khalid Khashoggi, Manal Halwani,
et al.
using the
Maxwell RSC miRNA Plasma and Serum Kit
(Cat. No.
AS1680
,
Promega
, Madison, WI, USA) on the
Maxwell RSC Instrument
, in accordance with the manufacturer’s instructions. Total RNA concentration was quantified using the
(6)
Streptococcus agalactiae Serotype Ia ST7 CC1 in Farmed Nile Tilapia in Latin America: Age-Dependent Disease Expression and Antimicrobial Susceptibility of an Emerging Clonal Lineage
Pathogens
May 18, 2026
Marco Rozas-Serri, Miguel Fernandez-Alarcon, Mariene Miyoko-Natori, Renata Galetti, Ricardo Harakava, Mateus Cardoso-Guimarães, Ricardo Ildefonso
manufacturer’s instructions. Bacterial genomic DNA was then semi-automatically extracted using the
Maxwell® RSC instrument
for the RSC Genomic DNA Kit (
Promega Corporation
, Madison, WI, USA) according to the manufacturer’s
(7)
Evaluating fecal inflammation biomarkers for non-invasive detection of weaning-related intestinal inflammation in piglets
J Anim Sci
May 9, 2026
Júlia Suppi, Eudald Llauradó-Calero, Jaume Coma, Anna Pelegrí-Pineda, Yolanda Saco, Anna Bassols, David Solà-Oriol
RNA was performed using
Maxwell® RSC simplyRNA Tissue Kit
(
Promega Corporation
, Madison, WI, US) in a
Maxwell ® RSC instrument
(
Promega Corporation
, Madison, WI, US). Quantification of total RNA was carried out in a NanoDrop ND-1000
(8)
Chloroplast stress caused by maltose hyperaccumulation activates chlorophagy via the core autophagy machinery
Plant Physiol
May 8, 2026
Sakuya Nakamura, Mayumi Wakazaki, Mayuko Sato, Kiminori Toyooka, Atsushi J Nagano, Hiroyuki Ishida, Shinya Hagihara, Masanori Izumi
shown.
RT-qPCR
Total RNA was isolated from rosette leaves using a
Maxwell RSC Plant RNA Kit
(
Promega
) and a
Maxwell RSC instrument
(
Promega
). The third rosette leaves from 2 plants were pooled as a sample. Equal amounts of total RNA
(9)
Globodera pallida virulence on major potato resistance has a common genetic basis across Western Europe
PLoS Pathog
May 6, 2026
Arno S. Schaveling, Leidy van Rijt, Yoonseon Do, Nike Soffree, Daan Langendoen, Hilde Room, André Machado Bertran, Margien Raven, Sebastiaan P. van Kessel, Evelyn Y.J. van Heese,
et al.
DNA was extracted using the
Maxwell RSC PureFood GMO and Authentication Kit
in combination with the
Maxwell RSC instrument
(
Promega
, USA) following the manufacturer’s instructions. This yielded between 4.1 and 11.3 ng/ μL of
(10)
Evaluating Viral Pollution in Wastewater and Mediterranean Ecosystems
Food Environ Virol
April 29, 2026
Pablo Puchades-Colera, Inés Girón-Guzmán, Enric Cuevas-Ferrando, Azahara Díaz-Reolid, Irene Falcó, Rosa Aznar, Marinella Farré, Marta Llorca, Alba Pérez-Cataluña, Gloria Sánchez
concentrates (300 µL), as well as from biosolids and sediment suspensions (300 µL), was performed using the
Maxwell® RSC Instrument
(
Promega
, Madison, USA) in combination with the Maxwell RSC Pure Food GMO and authentication kit, following
(11)
Dietary 1.3-1.6 yeast β-glucans enhance immune response and disease resilience in European seabass challenged with Tenacibaculum maritimum
Frontiers in Immunology
April 20, 2026
Miguel Cabano, Nadège Richard, Julie Schulthess, Lourenço Ramos-Pinto, Francisco Pinto-Cunha, Maria João Peixoto, Cláudia Aragão, Benjamin Costas
was extracted from posterior gut and skin tissues (n = 16, per diet ×
infection
condition) using the
Maxwell® RSC Instrument
(
Promega
, USA) and the
Maxwell® RSC simplyRNA Tissue Kit
, following the manufacturer’s instructions.
(12)
Extracellular Vesicle-Associated miR-222-3p and miR-186-5p as Potential Hypoxic Markers in Canine Osteosarcoma: A Preliminary In Vitro Study
Animals (Basel)
April 20, 2026
Raffaella De Maria, Manuela Poncina, Sara Divari, Lorenza Parisi, Sonia Capellero, Luiza Cesar Conti, Eugenio Mazzone, Federica Fratini, Luca Aresu, Lorella Maniscalco
No.
AS1680
, Madison, WI, USA) according to the manufacturer’s instructions, employing the automated
Maxwell® RSC instrument
(
Promega
, Madison, WI, USA) to ensure consistent yield and minimize manual handling.
MiRNA
concentration
(13)
Validation of a Duplex Digital PCR Assay for the Quantification of the NK603 Maize Event Across Three dPCR Platforms
Foods
April 14, 2026
Daniela Verginelli, Katia Spinella, Sara Ciuffa, Raffaele Carrano, Davide La Rocca, Elisa Pierboni, Monica Borghi, Silvana Farneti, Ugo Marchesi
starting from 200 mg of CRMs was performed using the Maxwell® RSC PureFood GMO extraction method with the
Maxwell® RSC Instrument
(
Promega Corporation
, Madison, WI, USA), according to the manufacturer’s instructions, for the Bio-Rad
(14)
Molecular Sex Determination in Caenophidian Snakes Using qPCR Amplification of Sex-Linked Genes: Validation and Interspecific Comparison
Animals (Basel)
April 11, 2026
George Iulian Enacrachi, Anamaria Ioana Paştiu, Dana Liana Pusta
dorsal trunk region of the exuvium (Figure 2) to standardize sampling across individuals, using the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA) and the
Maxwell® RSC Genomic DNA Kit
(
Promega
, USA), following the manufacturer’s
(15)
Targeting noncanonical TGF-beta signaling: inhibition effects on the human keloid fibroblast transcriptome
Itch (Phila)
April 10, 2026
Jordan Morningstar, Athira Sivadas, Martin Romeo, Silvia Vaena, Manuel Valdebran, Shawn G. Kwatra, Russell A. Norris, Tyler C. Beck
extracted using the Promega Maxwell RSC automated instrument (
Promega Corporation
; catalog number:
AS4500
). Poly(A) enrichment was performed using the
NEBNext Poly(A) mRNA Magnetic Isolation Module
(
New England Biolabs
(16)
Deruxtecan-based antibody–drug-conjugates induce senescence in HER2-positive breast cancer
Scientific Reports
April 9, 2026
Elena Vezzoli, Riccardo Pinos, Silvia Galbiati, Desiree Zambroni, Chiara Dall’Ara, Alberta Locatelli, Emanuele Colombo, Barbara Galbardi, Lucia Viganò, Zeno Lavagnino,
et al.
°C.
Maxwell® RSC Whole blood DNA kit
(AS 1520) was used to extract DNA from cell pellets employing the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA). DNA was eluted in 50 µL of
Elution Buffer
. The ddPCR mix was prepared in
(17)
Genome-Scale Phylogenetic Evidence Supports the Synonymy of Lasiodiplodia brasiliensis with Lasiodiplodia theobromae
J Fungi (Basel)
April 8, 2026
Celynne Ocampo-Padilla, Yoshiki Takata, Shunsuke Nozawa, Yui Harada, Katsuhiko Ando, Kyoko Watanabe
processed using the CTAB method combined with the
Maxwell® RSC PureFood GMO and Authentication Kit
on a
Maxwell® RSC instrument
(
Promega Corporation
, Fitchburg, WI, USA). DNA concentration and quality were assessed using a NanoDrop
(18)
A Simple and Fast Protocol to Detect Nucleophosmin 1 (NPM1) Mutation and Fms-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3/ITD): Optimizing Laboratory Routine
Methods Protoc
April 3, 2026
Alessandra Helena da Silva Hellwig, Gisele Menezes Ewald, Grazielle Motta Rodrigues, William Latosinski Matos, Juliana Bergmann, Viviane Horn de de Melo, Rodrigo Minuto Paiva, Dariane Castro Pereira, Eduardo Wandame Gomez
PCR-96-AB-C
). 2.3. Equipment
Maxwell® RSC Instrument
(
Promega Corporation
, Madison, WI, USA; Cat. no.:
AS4500
);NanoDrop™ 2000 Spectrophotometers (
Thermo Fisher Scientific
, Waltham, MA, USA; Cat. no.:
ND-2000
);Benchtop
(19)
CD9 regulates macrophage-mediated remodeling of adipose tissue in obesity
JCI Insight
March 23, 2026
Julia Chini, Nicole DeMarco, Dana V. Mitchell, Sam J. McCright, Kaitlyn M. Shen, Divyansi Pandey, Rachel L. Clement, Jessica Miller, Rajan Jain, Deanne M. Taylor,
et al.
(Promega, AD1340). Briefly, tissue was homogenized in Thioglycerol Homogenization solution using a
Maxwell RSC instrument
(
Promega
). RNA was quantified using a
NanoDrop 8000 spectrophotometer
(
Thermo Fisher Scientific
) and
(20)
Lipidomics of allantoic fluid collected by allantocentesis indicates a possible mechanism underlying partial litter loss in multifetal pregnancies of ewes
Scientific Reports
March 18, 2026
Tamir Alon, Maya Ross, Jen Spirer, Priscila Dos Santos Silva, Alexander Rosov, Lila Lifshitz, Gitit Kra, Moran Gershoni, Sergey Malitsky, Maxim Itkin,
et al.
performed by Maxwell® RSC simplyRNA Kit (#
AS1390
,
Promega
, WI, USA) in a
Maxwell® RSC Instrument
(#
AS4500
,
Promega
). A total of 200 µL of each sample was transferred into a 1.5-mL microfuge tube along with
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Maxwell RSC Instrument from Promega
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