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Automated DNA/RNA Purification Sample Preparation Workstations
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
Be the first to write a review!
Citations:
(862)
Figures:
(1)
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Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV Lamp
Avg. lifetime approximately 6,000 hrs
Molecular Weight
~85kDa
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (862)
(1)
Can GM soybean be reliably quantified after screening? A risk-based approach for optimizing GMO testing workflow
GM Crops Food
December 31, 2026
Davide La Rocca, Katia Spinella, Pietro Franceschi, Daniela Verginelli, Sara Ciuffa, Marisa Misto, Cinzia Quarchioni, Cristiana Fusco, Stefania Peddis, Pamela Bonini,
et al.
DNA Estractor FAST (©Generon S.p.A, Italy) and later with the RSC PureFood GMO by using an extractor
Maxwell®RSC Instrument
(
Promega
Madison, WI, USA), according to the manufacturer’s instructions. As a test portion, 2 g of
(2)
High-throughput analyses of Phocaeicola vulgatus reveal fitness determinants for gut colonization and during colitis
Gut Microbes
December 31, 2026
Nazik M. Elmekki, Michael J. Coyne, Katia Flores, Leonor García-Bayona, Laurie E. Comstock
Family Institute Microbiome
Metagenomics
Facility (DFI-MMF). Following nucleic acid recovery using a
Maxwell RSC instrument
(
Promega Corporation
, Madison, WI), DNAse treatment and elution, the samples were quantified using Qubit
(3)
Circulating Cell-Free DNA Analysis for Diagnostic and Prognostic Assessment of Hepatocellular Carcinoma in Cirrhosis
Int J Mol Sci
June 20, 2026
Inés Aznar-Peralta, Amparo Roa-Colomo, Javier López Hidalgo, Cristobal Fresno, Valeria Denninghoff, María José Serrano
cfDNA cfDNA was extracted from plasma samples using the Maxwell® RSC cfDNA LV Plasma Kit with the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA). The obtained cfDNA was immediately quantified using the
Qubit dsDNA HS Assay Kit
(4)
Multiplex gene editing suppresses random integration of hepatitis B virus DNA in chronically infected liver
Mol Ther Nucleic Acids
June 16, 2026
Samuel Slattery, Wenwen Huo, Amena Arif, Jennifer Gordon, Ryo Takeuchi
incubated at 80°C for 30 min prior to loading into the Maxwell RSC blood DNA cartridge and ran on the
Maxwell RSC instrument
. Genomic DNA was extracted from 293FT cells using a
Maxwell RSC Cultured Cells DNA Kit
(
Promega
) according
(5)
Environmental Pollutant PCB 153 Is Associated with Candidate Alternative Splicing Alterations in Intellectual Disability-Associated Genes: An Exploratory RNA-Seq Splicing Analysis in a Neuronal Model
Genes (Basel)
June 13, 2026
Maria Lui, Aurelio Minuti, Simone D'Angiolini, Michele Scuruchi, Serena Silvestro, Osvaldo Artimagnella
resulting cell pellets using the
Maxwell® RSC simplyRNA Cells Kit
(
Promega
, Madison, WI, USA) on the
Maxwell® RSC Instrument
, following the manufacturer’s instructions. For library preparation, 100 ng of total RNA from two biological
(6)
Methods for detecting highly pathogenic avian influenza H5N1 virus in dairy processing environments
Front Microbiol
June 4, 2026
Pablo Puchades-Colera, Inés Girón-Guzmán, Alba Pérez-Cataluña, Gloria Sánchez
triplicate. In parallel with the concentration step, our study compared the analytical performance of the
Maxwell® RSC Instrument
(
Promega
, Madison, USA) nucleic acid extraction protocol using the Maxwell RSC Pure Food GMO and authentication
(7)
Cancer of unknown primary genomic profiling from cell-free DNA provides insights into CUP biology and vulnerabilities
Front Med (Lausanne)
June 3, 2026
Roberta Roncarati, Beatrice Fontana, Ilaria Pace, Giorgio Durante, Nicole Conci, Alessia Soru, Giulia Gallerani, Mattia Riefolo, Irene Salamon, Noemi Laprovitera,
et al.
use. Cell-free DNA (cfDNA) was extracted from 1 mL of plasma using the
Maxwell RSC instrument
(Cat No:
AS4500
,
Promega
, Madison, WI, USA) with the
Maxwell RSC ccfDNA Plasma Kit
(Cat No:
AS1480
,
Promega
), according
(8)
Functional Characterization of a Novel Homozygous DNAH5 Single-Nucleotide Intronic Deletion in a Consanguineous Portuguese Family with Primary Ciliary Dyskinesia
Cells
June 2, 2026
Catarina Hilário, Sara Raimundo, Catarina Dias, Joana Saramago, Telma Oliveira, Rute Pereira, Sofia Quental, João Parente Freixo, Luís Gales, Jorge Oliveira,
et al.
were immediately immersed in RNAlater (Thermo Fisher Scientific), and total RNA was isolated using the
Maxwell® RSC Instrument
and the
Maxwell® RSC simplyRNA Tissue Kit
(
Promega
, Madison, WI, USA), following the manufacturer’s
(9)
Phenotypic heterogeneity shapes phage resistance and cocktail efficacy in Klebsiella pneumoniae
Microbiology Spectrum
June 2, 2026
Lucas Mora-Quilis, Rafael Sanjuán, Pilar Domingo-Calap
concentrated lysate was used to extract DNA from viral capsids using an automated protocol with the
Maxwell RSC Instrument
(
Promega
). DNA libraries were generated using the Illumina Nextera XT DNA kit (2 × 150 bp or 2 × 250
(10)
Performance of Seven-Gene Panel Testing for Risk Stratification of Thyroid Nodules with Indeterminate Cytology Results
Int J Mol Sci
May 30, 2026
Ann-Kristin Jochum, Frida Renström, Barbara Bischofberger-Baumann, Izadora Demmer, René Schönegg, Michael Brändle, Stefan Bilz, Wolfram Jochum
FNA material was available. Total nucleic acids were extracted from liquid-based FNA samples using a
Maxwell RSC instrument
(
Promega
, Madison, WI, USA) with the
Maxwell RSC Viral Total Nucleic Acid Purification Kit
(
Promega
)
(11)
A guide for establishing patient-derived organoids from bile samples obtained during endoscopic procedures and performing gene expression knockdown
Frontiers in Cell and Developmental Biology
May 29, 2026
Carla Rojo, Juan J. Vila, Laura Guembe, Amaia Arrubla-Gamboa, Vanesa Jusué-Irurita, Juan Carrascosa-Gil, María Rullan, Javier Rández-Garbayo, Maite G. Fernández-Barrena, Meritxell Huch,
et al.
the final
centrifugation
step (prior to Matrigel re-embedding).RNA is extracted using the automated
Maxwell RSC Instrument
with the Maxwell RSC simply RNA Tissue kit (
Promega
, Madison, WI, United States of America) following
(12)
Deciphering macrophage molecular responses to Porphyromonas gingivalis outer membrane vesicles through combined immunoassay and Raman spectroscopic analyses
Frontiers in Microbiology
May 29, 2026
Yoshiyuki Matsuo, Aoi Son, Sara Gentile, Riccardo Bernola, Takashi Yamashita, Saki Ikegami, Lucia Sileo, Luna Ardondi, Toru Kariu, Barbara Zavan,
et al.
IFN-γ (0.02 μg/mL) for 16 h. Total RNA was extracted using the
Maxwell RSC simplyRNA Cells Kit
and the
Maxwell RSC Instrument
(
Promega
, Co., Madison, WI, United States). One microgram of total RNA was reverse transcribed into
(13)
Cuproptosis inducers mediate cold lethality via SLCR-46.1 in C. elegans
Nat Commun
May 27, 2026
Serina Yamashiro, Satomi Mizuno, Haruka Motomura, Aidan T. Pezacki, Yukina Mori, Christopher J. Chang, Akane Ohta, Atsushi Kuhara
using the Maxwell RSC Simply RNA Tissue Kit (
Promega
;
AS1340
) and the
Maxwell RSC Instrument
(
Promega
;
AS4500
), following the manufacturer’s instructions.
Sequencing
libraries were prepared with the TruSeq Stranded
(14)
Method optimization of protein and nucleic acid extraction from skin tape strip samples for biomarker analysis
Frontiers in Medicine
May 25, 2026
Erika L. Boarder, Jessica L. Moore, Kyra A. Richardson, Angelina Volkova, Danielle Guttierez, Cynthia D. Timmers, Susan H. Smith
(Qiagen, RNeasy Mini Kit, Hilden, Germany), (b) automated bead-based extraction and
purification
using the
Maxwell RSC Instrument
(
Promega
, Madison, WI, United States), or (c) lysis in Buffer RLT, containing guanidine thiocyanate,
(15)
Circulating Tumor DNA and microRNA–Based Liquid Biopsy for Longitudinal Treatment Monitoring and Recurrence Prediction in Pediatric Sarcomas: A Prospective Cohort Study
Oncology Research
May 21, 2026
Maher Kurdi, Amber Hassan, Bashar Reda, Anas Nooh, Mohammed Alsobaie, Alaa Alkhotani, Dahlia S. Mirdad, Majid Almansouri, Khalid Khashoggi, Manal Halwani,
et al.
using the
Maxwell RSC miRNA Plasma and Serum Kit
(Cat. No.
AS1680
,
Promega
, Madison, WI, USA) on the
Maxwell RSC Instrument
, in accordance with the manufacturer’s instructions. Total RNA concentration was quantified using the
(16)
Streptococcus agalactiae Serotype Ia ST7 CC1 in Farmed Nile Tilapia in Latin America: Age-Dependent Disease Expression and Antimicrobial Susceptibility of an Emerging Clonal Lineage
Pathogens
May 18, 2026
Marco Rozas-Serri, Miguel Fernandez-Alarcon, Mariene Miyoko-Natori, Renata Galetti, Ricardo Harakava, Mateus Cardoso-Guimarães, Ricardo Ildefonso
manufacturer’s instructions. Bacterial genomic DNA was then semi-automatically extracted using the
Maxwell® RSC instrument
for the RSC Genomic DNA Kit (
Promega Corporation
, Madison, WI, USA) according to the manufacturer’s
(17)
Evaluating fecal inflammation biomarkers for non-invasive detection of weaning-related intestinal inflammation in piglets
J Anim Sci
May 9, 2026
Júlia Suppi, Eudald Llauradó-Calero, Jaume Coma, Anna Pelegrí-Pineda, Yolanda Saco, Anna Bassols, David Solà-Oriol
RNA was performed using
Maxwell® RSC simplyRNA Tissue Kit
(
Promega Corporation
, Madison, WI, US) in a
Maxwell ® RSC instrument
(
Promega Corporation
, Madison, WI, US). Quantification of total RNA was carried out in a NanoDrop ND-1000
(18)
Chloroplast stress caused by maltose hyperaccumulation activates chlorophagy via the core autophagy machinery
Plant Physiol
May 8, 2026
Sakuya Nakamura, Mayumi Wakazaki, Mayuko Sato, Kiminori Toyooka, Atsushi J Nagano, Hiroyuki Ishida, Shinya Hagihara, Masanori Izumi
shown.
RT-qPCR
Total RNA was isolated from rosette leaves using a
Maxwell RSC Plant RNA Kit
(
Promega
) and a
Maxwell RSC instrument
(
Promega
). The third rosette leaves from 2 plants were pooled as a sample. Equal amounts of total RNA
(19)
Globodera pallida virulence on major potato resistance has a common genetic basis across Western Europe
PLoS Pathog
May 6, 2026
Arno S. Schaveling, Leidy van Rijt, Yoonseon Do, Nike Soffree, Daan Langendoen, Hilde Room, André Machado Bertran, Margien Raven, Sebastiaan P. van Kessel, Evelyn Y.J. van Heese,
et al.
DNA was extracted using the
Maxwell RSC PureFood GMO and Authentication Kit
in combination with the
Maxwell RSC instrument
(
Promega
, USA) following the manufacturer’s instructions. This yielded between 4.1 and 11.3 ng/ μL of
(20)
Evaluating Viral Pollution in Wastewater and Mediterranean Ecosystems
Food Environ Virol
April 29, 2026
Pablo Puchades-Colera, Inés Girón-Guzmán, Enric Cuevas-Ferrando, Azahara Díaz-Reolid, Irene Falcó, Rosa Aznar, Marinella Farré, Marta Llorca, Alba Pérez-Cataluña, Gloria Sánchez
concentrates (300 µL), as well as from biosolids and sediment suspensions (300 µL), was performed using the
Maxwell® RSC Instrument
(
Promega
, Madison, USA) in combination with the Maxwell RSC Pure Food GMO and authentication kit, following
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Maxwell RSC Instrument from Promega
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