Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(41) Targeting noncanonical TGF-beta signaling: inhibition effects on the human keloid fibroblast transcriptomeItch (Phila)April 10, 2026Jordan Morningstar, Athira Sivadas, Martin Romeo, Silvia Vaena, Manuel Valdebran, Shawn G. Kwatra, Russell A. Norris, Tyler C. Beckextracted using the Promega Maxwell RSC automated instrument (Promega Corporation; catalog number: AS4500). Poly(A) enrichment was performed using the NEBNext Poly(A) mRNA Magnetic Isolation Module (New England Biolabs

(42) Genetic landscape of stage II melanoma identifies CBL as a new driver gene and prognostic biomarkerBritish Journal of CancerApril 9, 2026Elena Sophia Lindner, Jakob Admard, German Demidov, Sorin Armeanu-Ebinger, Tobias Sinnberg, Heike Niessner, Teresa Amaral, Claus Garbe, Andrea Forschner, Olga Kelemen, et al.isolated from 8 µm tumour and normal tissue paraffin sections using the Maxwell® RSC DNA FFPE Kit and the Maxwell® RSC Instrument (Promega, Madison, WI, USA) according to the manufacturer’s instructions. Library construction, hybrid

(43) Deruxtecan-based antibody–drug-conjugates induce senescence in HER2-positive breast cancerScientific ReportsApril 9, 2026Elena Vezzoli, Riccardo Pinos, Silvia Galbiati, Desiree Zambroni, Chiara Dall’Ara, Alberta Locatelli, Emanuele Colombo, Barbara Galbardi, Lucia Viganò, Zeno Lavagnino, et al.°C. Maxwell® RSC Whole blood DNA kit (AS 1520) was used to extract DNA from cell pellets employing the Maxwell® RSC Instrument (Promega, Madison, WI, USA). DNA was eluted in 50 µL of Elution Buffer. The ddPCR mix was prepared in

(44) Genome-Scale Phylogenetic Evidence Supports the Synonymy of Lasiodiplodia brasiliensis with Lasiodiplodia theobromaeJ Fungi (Basel)April 8, 2026Celynne Ocampo-Padilla, Yoshiki Takata, Shunsuke Nozawa, Yui Harada, Katsuhiko Ando, Kyoko Watanabeprocessed using the CTAB method combined with the Maxwell® RSC PureFood GMO and Authentication Kit on a Maxwell® RSC instrument (Promega Corporation, Fitchburg, WI, USA). DNA concentration and quality were assessed using a NanoDrop

(45) A Simple and Fast Protocol to Detect Nucleophosmin 1 (NPM1) Mutation and Fms-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3/ITD): Optimizing Laboratory RoutineMethods ProtocApril 3, 2026Alessandra Helena da Silva Hellwig, Gisele Menezes Ewald, Grazielle Motta Rodrigues, William Latosinski Matos, Juliana Bergmann, Viviane Horn de de Melo, Rodrigo Minuto Paiva, Dariane Castro Pereira, Eduardo Wandame GomezPCR-96-AB-C). 2.3. Equipment Maxwell® RSC Instrument (Promega Corporation, Madison, WI, USA; Cat. no.: AS4500);NanoDrop™ 2000 Spectrophotometers (Thermo Fisher Scientific, Waltham, MA, USA; Cat. no.: ND-2000);Benchtop

(46) CD9 regulates macrophage-mediated remodeling of adipose tissue in obesityJCI InsightMarch 23, 2026Julia Chini, Nicole DeMarco, Dana V. Mitchell, Sam J. McCright, Kaitlyn M. Shen, Divyansi Pandey, Rachel L. Clement, Jessica Miller, Rajan Jain, Deanne M. Taylor, et al.(Promega, AD1340). Briefly, tissue was homogenized in Thioglycerol Homogenization solution using a Maxwell RSC instrument (Promega). RNA was quantified using a NanoDrop 8000 spectrophotometer (Thermo Fisher Scientific) and

(47) Lipidomics of allantoic fluid collected by allantocentesis indicates a possible mechanism underlying partial litter loss in multifetal pregnancies of ewesScientific ReportsMarch 18, 2026Tamir Alon, Maya Ross, Jen Spirer, Priscila Dos Santos Silva, Alexander Rosov, Lila Lifshitz, Gitit Kra, Moran Gershoni, Sergey Malitsky, Maxim Itkin, et al.performed by Maxwell® RSC simplyRNA Kit (#AS1390, Promega, WI, USA) in a Maxwell® RSC Instrument (#AS4500, Promega). A total of 200 µL of each sample was transferred into a 1.5-mL microfuge tube along with

(48) Impact of Semi-Permanent Nail Polish on Forensic DNA Profiling and Phenotyping from FingernailsGenes (Basel)March 16, 2026Giulia Fazio, Sara Amurri, Arianna Giorgetti, Filomena Melchionda, Chiara Turchi, Susi Pelotti, Carla Binisamples was performed using the Maxwell® FSC DNA IQ™ Casework Kit (Promega, Madison, WI, USA) on a Maxwell® RSC Instrument, following the manufacturer’s protocol, “Automated Purification of DNA from Fingernail Clippings”. The

(49) Behavioral screening defines the molecular Parkinsonism-related subgroups in DrosophilaNature CommunicationsMarch 10, 2026Natalie Kaempf, Jorge S. Valadas, Pieter Robberechts, Nils Schoovaerts, Roman Praschberger, Antonio Ortega, Eliana Nachman, Lorenzo Ghezzi, Ayse Kilic, Dries Chabot, et al.Pink1KO-WS/y, for which we only used hemizygous males, at 1–5 days after eclosion. RNA was extracted using Maxwell RSC instrument and Maxwell RSC RNA kit (Promega) and transcribed using the SuperScript VILO cDNA Synthesis Kit (ThermoFisher Scientific

(50) Somatic and germline genomic variation in thymic carcinomasESMO OpenMarch 10, 2026F. Tettamanzi, C. De Carlo, C. Cappadona, D. Giuliano, V. Rimoldi, C. Piombo, L.G. Cecchi, S. Zanella, G. Marulli, E. Voulaz, et al.extracted from FFPE samples, using the Maxwell® RSC DNA FFPE Kit (Promega Corporation, Madison, WI) on a Maxwell® RSC instrument (Promega Corporation); gDNA extraction from blood samples was carried out using a Microlab STAR Liquid

(51) Clonal Dynamics of FLT3-ITD from Diagnosis to Relapse: Ultra-Sensitive Patient-Specific Monitoring by ddPCRInt J Mol SciMarch 8, 2026Alessandro Ferrando, Johanna Umurungi, Alice Costanza Danzero, Antonio Frolli, Rita Vacca, Arianna Savi, Giovanni Fornari, Valentina Gaidano, Alessandro Cignetti, Beatrice Sani, et al.from whole blood using the Maxwell RSC Blood DNA Kit (Promega, Madison, WI, USA) and processed on the Maxwell® RSC Instrument (Promega, Madison, WI, USA) according to the manufacturer’s instructions. DNA concentration and purity

(52) Binary vector origin predictably determines Agrobacterium -mediated transformation outcome across eukaryotic kingdomsbioRxivMarch 7, 2026Matthew J. Szarzanowicz, Michael Busche, Ziyu Dai, Nathan Lapp, Gina M. Geiselman, Jiayuan Jia, Lucas M. Waldburger, Yan Liang, Guoliang Yuan, Rylan Duong, et al.(BioSpec Products, Inc, Bartlesville, OK, USA). DNA was purified using the Maxwell® RSC plant DNA kit by the Maxwell® RSC instrument (Promega, Madison, WI, USA). Transgene insertion number quantification Transgene insertion number

(53) Identification of a miRNA signature for schizophrenia in plasma-derived extracellular vesiclesbioRxiv : the preprint server for biologyMarch 6, 2026Collier MEW, Chiappelli J, Marshall H, Sylvius N, Allcock N, Whittingham J, Kochunov P, Schwarcz R, Hong EL, Giorgini F.was isolated from the EV lysates using the Maxwell RSC miRNA from plasma and serum kit (Promega) on a Maxwell RSC instrument (Promega) according to the manufacturer’s instructions and eluted in 40 μl of nuclease free water. RT-qPCR

(54) Targeted BDNF upregulation via upstream open reading frame disruptionMolecular TherapyMarch 4, 2026Ning Feng, Thomas Goedert, Nenad Svrzikapa, Dongnan Yan, Hans J. Friedrichsen, Britt Hanson, Alicia Ljungdahl, Ruxandra Dafinca, Kevin Talbot, Stephan J. Sanders, et al.1. RT-qPCR To quantify firefly and Renilla luciferase transcripts, total RNA was first extracted using the Maxwell RSC Instrument and the Maxwell RSC simplyRNA Tissue Kit (both Promega). Reverse transcription was performed using the

(55) Pediatric H3 G34-mutant diffuse hemispheric glioma: clinical, imaging and molecular prognostic factors, MGMT expression, and temozolomide responseActa NeuropatholMarch 2, 2026Dana Tlais, Qunyu Zhang, Jordan T. Roach, Christopher L. Tinkle, Tong Lin, Xiaoyu Li, Ayatullah Mostafa, Daniel C. Moreira, Rene Y. McNall-Knapp, Sarah Z. Rush, et al.guidelines. Whole genome sequencing Genomic DNA was extracted from snap-frozen tumor tissue using an automated Maxwell RSC Instrument (Promega), as previously described [6, 15, 18]. DNA quality was assessed on a 4200 TapeStation (Agilent).

(56) Impact of Heterogeneous DNA Methylation on the Accuracy of Quantitative Methylation-Specific PCR for Detecting DNA Hypermethylation in Prostate CancerInternational Journal of Molecular SciencesFebruary 27, 2026Wieke C. H. Visser, Hans de Jong, Laureen B. Janssen, Jolly Shrivastava, Peter F. A. Mulders, Jack A. Schalken, Willem J. G. MelchersUSA) to concentrate large-volume urine samples prior to extraction, followed by extraction using the Maxwell RSC Instrument (Promega Corporation, Madison, WI, USA), with the Maxwell RSC miRNA Plasma and Serum Kit (cat. no. AS1460,

(57) Prospective multicenter study of ctDNA versus tumor tissue guiding FGFR-targeted therapy in metastatic urothelial cancerNature CommunicationsFebruary 27, 2026David C. Müller, Andrew J. Murtha, Jack V. W. Bacon, Maria Stephenson, Connor Wells, Carlos Vasquez-Rios, Kimia Rostin, Lisa Rebane, Elena Schönlau, Jussi Nikkola, et al.using the QIAGEN DNeasy Blood and Tissue Kit, or the Promega Maxwell® RSC Blood DNA Kit and Promega Maxwell® RSC Instrument. Extracted gDNA was quantified with a NanoDrop spectrophotometer. cfDNA libraries were generated using

(58) Parasitic surveillance in wolves of central Italy: a focus on the Abruzzo regionParasites & VectorsFebruary 21, 2026Sabrina Vanessa Patrizia Defourny, Mariasole Colombo, Gianluca D’Amico, Stefania Salucci, Antonio Cocco, Maria Chiara Cantelmi, Daniela Averaimo, Marco Rulli, Gianfranco Romeo, Susanna Tora, et al.min. DNA was extracted from the sediment using the standardized lysis and purification protocol of the Maxwell RSC® Instrument Genomic Kit (Promega, Madison, WI, USA). DNA was analyzed by real-time PCR (qPCR) [23] to detect Leishmania

(59) Detection of structural DNA variants in medulloblastomas using optical genome mappingActa Neuropathologica CommunicationsFebruary 11, 2026Nadezhda Kubon, Mirela Bălan, David Koppstein, Sophia Praeger, Marietta Wolter, Peter Ebert, David Pauck, Jörg Felsberg, Thomas Beez, Daniel Picard, et al.extracted from fresh-frozen MB tissue samples (n = 29) using the Maxwell® RSC simplyRNA Tissue Kit and Maxwell® RSC Instrument (Promega). RNA sequencing libraries were prepared either with the Illumina Stranded Total RNA Prep,

(60) Enhanced virulence of mpox virus clade Ib over clade IIb in the CAST/EiJ mouse modelCommunications BiologyFebruary 11, 2026Alazne R. Unanue, Rocío Martín, Carolina Sánchez, Isabel Alonso-Sánchez, Ana Moraga-Quintanilla, Laura Fernandez del Ama, Pedro J. Sánchez-Cordón, Antonio Alcamí, Bruno HernáezDNA was isolated from homogenized MPXV infected organs using Maxwell RSC Viral TNA kit (Promega) and Maxwell RSC instrument (Promega) and finally eluted in 50 μl nuclease free water. We set up a multiplex RT-qPCR to detect viral

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