Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(41) Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and PlasmidsZoonoses and Public HealthJune 15, 2026Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwichextracted using the Maxwell RSC Cultured Cell DNA Kit (Promega) on semiautomated DNA extraction machines (Maxwell RSC Instrument, Promega), following the manufacturer's instructions. DNA was quantified using the QuantiFluor ONE dsDNA System

(42) Environmental Pollutant PCB 153 Is Associated with Candidate Alternative Splicing Alterations in Intellectual Disability-Associated Genes: An Exploratory RNA-Seq Splicing Analysis in a Neuronal ModelGenes (Basel)June 13, 2026Maria Lui, Aurelio Minuti, Simone D'Angiolini, Michele Scuruchi, Serena Silvestro, Osvaldo Artimagnellaresulting cell pellets using the Maxwell® RSC simplyRNA Cells Kit (Promega, Madison, WI, USA) on the Maxwell® RSC Instrument, following the manufacturer’s instructions. For library preparation, 100 ng of total RNA from two biological

(43) Immunopeptidomics-guided identification of functional neoantigens in non-small cell lung cancernpj Precision OncologyJune 10, 2026Ben Nicholas, Alistair Bailey, Katy J. McCann, Oliver Wood, Eve Currall, Peter Johnson, Tim Elliott, Christian Ottensmeier, Paul Skippnitrogen. Ten to twenty 10 µm cryosections were used for nucleic acid extraction using the automated Maxwell® RSC instrument (Promega) with the appropriate sample kit and according to the manufacturer’s instructions: Maxwell

(44) Methods for detecting highly pathogenic avian influenza H5N1 virus in dairy processing environmentsFront MicrobiolJune 4, 2026Pablo Puchades-Colera, Inés Girón-Guzmán, Alba Pérez-Cataluña, Gloria Sáncheztriplicate. In parallel with the concentration step, our study compared the analytical performance of the Maxwell® RSC Instrument (Promega, Madison, USA) nucleic acid extraction protocol using the Maxwell RSC Pure Food GMO and authentication

(45) Non-coding structural variants disrupt FOXG1 transcriptional regulation in early neurodevelopmentNature CommunicationsJune 3, 2026Lisa Hamerlinck, Eva D’haene, Michael B. Vaughan, Nore Van Loon, María del Rocío Pérez Baca, Sebastian Leimbacher, Michael Kosicki, Lara Colombo, Lukas Genbrugge, Lies Vantomme, et al.cultured in RPMI (Roswell Park Memorial Institute). RNA was extracted using the Maxwell® RSC instrument (AS4500, Promega) using the Maxwell® RSC Simply RNA Tissue kit (AS1340, Promega). Case lymphoblastoid cell lines

(46) Cancer of unknown primary genomic profiling from cell-free DNA provides insights into CUP biology and vulnerabilitiesFront Med (Lausanne)June 3, 2026Roberta Roncarati, Beatrice Fontana, Ilaria Pace, Giorgio Durante, Nicole Conci, Alessia Soru, Giulia Gallerani, Mattia Riefolo, Irene Salamon, Noemi Laprovitera, et al.use. Cell-free DNA (cfDNA) was extracted from 1 mL of plasma using the Maxwell RSC instrument (Cat No: AS4500, Promega, Madison, WI, USA) with the Maxwell RSC ccfDNA Plasma Kit (Cat No: AS1480, Promega), according

(47) Phenotypic heterogeneity shapes phage resistance and cocktail efficacy in Klebsiella pneumoniaeMicrobiology SpectrumJune 2, 2026Lucas Mora-Quilis, Rafael Sanjuán, Pilar Domingo-Calapconcentrated lysate was used to extract DNA from viral capsids using an automated protocol with the Maxwell RSC Instrument (Promega). DNA libraries were generated using the Illumina Nextera XT DNA kit (2 × 150 bp or 2 × 250

(48) Functional Characterization of a Novel Homozygous DNAH5 Single-Nucleotide Intronic Deletion in a Consanguineous Portuguese Family with Primary Ciliary DyskinesiaCellsJune 2, 2026Catarina Hilário, Sara Raimundo, Catarina Dias, Joana Saramago, Telma Oliveira, Rute Pereira, Sofia Quental, João Parente Freixo, Luís Gales, Jorge Oliveira, et al.were immediately immersed in RNAlater (Thermo Fisher Scientific), and total RNA was isolated using the Maxwell® RSC Instrument and the Maxwell® RSC simplyRNA Tissue Kit (Promega, Madison, WI, USA), following the manufacturer’s

(49) Performance of Seven-Gene Panel Testing for Risk Stratification of Thyroid Nodules with Indeterminate Cytology ResultsInt J Mol SciMay 30, 2026Ann-Kristin Jochum, Frida Renström, Barbara Bischofberger-Baumann, Izadora Demmer, René Schönegg, Michael Brändle, Stefan Bilz, Wolfram JochumFNA material was available. Total nucleic acids were extracted from liquid-based FNA samples using a Maxwell RSC instrument (Promega, Madison, WI, USA) with the Maxwell RSC Viral Total Nucleic Acid Purification Kit (Promega)

(50) Deciphering macrophage molecular responses to Porphyromonas gingivalis outer membrane vesicles through combined immunoassay and Raman spectroscopic analysesFrontiers in MicrobiologyMay 29, 2026Yoshiyuki Matsuo, Aoi Son, Sara Gentile, Riccardo Bernola, Takashi Yamashita, Saki Ikegami, Lucia Sileo, Luna Ardondi, Toru Kariu, Barbara Zavan, et al.IFN-γ (0.02 μg/mL) for 16 h. Total RNA was extracted using the Maxwell RSC simplyRNA Cells Kit and the Maxwell RSC Instrument (Promega, Co., Madison, WI, United States). One microgram of total RNA was reverse transcribed into

(51) A guide for establishing patient-derived organoids from bile samples obtained during endoscopic procedures and performing gene expression knockdownFrontiers in Cell and Developmental BiologyMay 29, 2026Carla Rojo, Juan J. Vila, Laura Guembe, Amaia Arrubla-Gamboa, Vanesa Jusué-Irurita, Juan Carrascosa-Gil, María Rullan, Javier Rández-Garbayo, Maite G. Fernández-Barrena, Meritxell Huch, et al.the final centrifugation step (prior to Matrigel re-embedding).RNA is extracted using the automated Maxwell RSC Instrument with the Maxwell RSC simply RNA Tissue kit (Promega, Madison, WI, United States of America) following

(52) Cuproptosis inducers mediate cold lethality via SLCR-46.1 in C. elegansNat CommunMay 27, 2026Serina Yamashiro, Satomi Mizuno, Haruka Motomura, Aidan T. Pezacki, Yukina Mori, Christopher J. Chang, Akane Ohta, Atsushi Kuharausing the Maxwell RSC Simply RNA Tissue Kit (Promega; AS1340) and the Maxwell RSC Instrument (Promega; AS4500), following the manufacturer’s instructions. Sequencing libraries were prepared with the TruSeq Stranded

(53) Method optimization of protein and nucleic acid extraction from skin tape strip samples for biomarker analysisFrontiers in MedicineMay 25, 2026Erika L. Boarder, Jessica L. Moore, Kyra A. Richardson, Angelina Volkova, Danielle Guttierez, Cynthia D. Timmers, Susan H. Smith(Qiagen, RNeasy Mini Kit, Hilden, Germany), (b) automated bead-based extraction and purification using the Maxwell RSC Instrument (Promega, Madison, WI, United States), or (c) lysis in Buffer RLT, containing guanidine thiocyanate,

(54) Circulating Tumor DNA and microRNA–Based Liquid Biopsy for Longitudinal Treatment Monitoring and Recurrence Prediction in Pediatric Sarcomas: A Prospective Cohort StudyOncology ResearchMay 21, 2026Maher Kurdi, Amber Hassan, Bashar Reda, Anas Nooh, Mohammed Alsobaie, Alaa Alkhotani, Dahlia S. Mirdad, Majid Almansouri, Khalid Khashoggi, Manal Halwani, et al.using the Maxwell RSC miRNA Plasma and Serum Kit (Cat. No. AS1680, Promega, Madison, WI, USA) on the Maxwell RSC Instrument, in accordance with the manufacturer’s instructions. Total RNA concentration was quantified using the

(55) Streptococcus agalactiae Serotype Ia ST7 CC1 in Farmed Nile Tilapia in Latin America: Age-Dependent Disease Expression and Antimicrobial Susceptibility of an Emerging Clonal LineagePathogensMay 18, 2026Marco Rozas-Serri, Miguel Fernandez-Alarcon, Mariene Miyoko-Natori, Renata Galetti, Ricardo Harakava, Mateus Cardoso-Guimarães, Ricardo Ildefonsomanufacturer’s instructions. Bacterial genomic DNA was then semi-automatically extracted using the Maxwell® RSC instrument for the RSC Genomic DNA Kit (Promega Corporation, Madison, WI, USA) according to the manufacturer’s

(56) USP29 ‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancerMolecular OncologyMay 13, 2026Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, et al.quantify the wounded area. 2.6 RNA isolation and RT‐qPCR Total RNA was automatically extracted using Maxwell® RSC instrument and Maxwell RSC simplyRNA Cells Kit (Promega) according to the manufacturers' instructions. RNA concentration

(57) Evaluating fecal inflammation biomarkers for non-invasive detection of weaning-related intestinal inflammation in pigletsJ Anim SciMay 9, 2026Júlia Suppi, Eudald Llauradó-Calero, Jaume Coma, Anna Pelegrí-Pineda, Yolanda Saco, Anna Bassols, David Solà-OriolRNA was performed using Maxwell® RSC simplyRNA Tissue Kit (Promega Corporation, Madison, WI, US) in a Maxwell ® RSC instrument (Promega Corporation, Madison, WI, US). Quantification of total RNA was carried out in a NanoDrop ND-1000

(58) Chloroplast stress caused by maltose hyperaccumulation activates chlorophagy via the core autophagy machineryPlant PhysiolMay 8, 2026Sakuya Nakamura, Mayumi Wakazaki, Mayuko Sato, Kiminori Toyooka, Atsushi J Nagano, Hiroyuki Ishida, Shinya Hagihara, Masanori Izumishown. RT-qPCR Total RNA was isolated from rosette leaves using a Maxwell RSC Plant RNA Kit (Promega) and a Maxwell RSC instrument (Promega). The third rosette leaves from 2 plants were pooled as a sample. Equal amounts of total RNA

(59) Globodera pallida virulence on major potato resistance has a common genetic basis across Western EuropePLoS PathogMay 6, 2026Arno S. Schaveling, Leidy van Rijt, Yoonseon Do, Nike Soffree, Daan Langendoen, Hilde Room, André Machado Bertran, Margien Raven, Sebastiaan P. van Kessel, Evelyn Y.J. van Heese, et al.DNA was extracted using the Maxwell RSC PureFood GMO and Authentication Kit in combination with the Maxwell RSC instrument (Promega, USA) following the manufacturer’s instructions. This yielded between 4.1 and 11.3 ng/ μL of

(60) Evaluating Viral Pollution in Wastewater and Mediterranean EcosystemsFood Environ VirolApril 29, 2026Pablo Puchades-Colera, Inés Girón-Guzmán, Enric Cuevas-Ferrando, Azahara Díaz-Reolid, Irene Falcó, Rosa Aznar, Marinella Farré, Marta Llorca, Alba Pérez-Cataluña, Gloria Sánchezconcentrates (300 µL), as well as from biosolids and sediment suspensions (300 µL), was performed using the Maxwell® RSC Instrument (Promega, Madison, USA) in combination with the Maxwell RSC Pure Food GMO and authentication kit, following

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