Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

Add to Compare List

Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(41) Methylation-specific, universal, and highly sensitive identification of ctDNA in prostate cancer by multiplex droplet digital PCRPLOS OneJanuary 29, 2026Søren Kahns, Ahmed H. Zedan, Mads M. Aagaard, Luisa M. D. Canto, Sanne Kjær-Frifeldt, Stine V. Eriksen, Christine V. Madsen, Jonna S. Madsen, Palle J. S. Osther, Torben F. Hansen, et al.mCRPC. Extraction of DNA from tissue, whole blood, and plasma DNA was extracted from FFPE biopsy specimens on the Maxwell RSC instrument using the Maxwell RSC FFPE Plus DNA Kit (Promega, Madison, WI, USA) according to the manufacturer’s

(42) Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade gliomaFrontiers in RadiologyJanuary 29, 2026Georg Gihr, Hans Henkes, Ali Khanafer, Mehdi Allouche, Oliver Ganslandt, Sebastian Johannes Müller, Walter Alexander Wohlgemuth, Stefan Schobparaffin-embedded tissue blocks using the Maxwell® RSC FFPE Plus DNA Kit AS1720 (Promega, Madison, WI, USA) and the Maxwell® RSC Instrument (Promega). The isolated DNA underwent bisulfite treatment using the EpiTect® Bisulfite Kit (QIAGEN,

(43) Surveillance of avian influenza viruses in migratory wild birds in South Korea, 2019–2025Journal of Veterinary ScienceJanuary 26, 2026Jae Kyung Lee, Min Beom Kim, Seo Hyeon Kim, Song Hwi Jeong, HaanWoo Sung, Hyung-Kwan Jang, Kang-Seuk Choi, Daesung Yoo, Se-Hee An, Gyeong-Beom Heo, et al.described [17]. Briefly, Viral RNA was directly extracted from pooled fecal supernatant sample using the Maxwell RSC instrument with Maxwell RSC simplyRNA Tissue Kit (Promega, Korea), and AI virus matrix (M), H5, and H7 real-time

(44) PCB 153 Modulates Genes Involved in Proteasome and Neurodegeneration-Related Pathways in Differentiated SH-SY5Y Cells: A Transcriptomic StudyCellsJanuary 23, 2026Aurelio Minuti, Serena Silvestro, Claudia Muscarà, Michele Scuruchi, Simone D’AngioliniRNA was then extracted using the Maxwell® RSC simplyRNA Cells Kit (Promega, Madison, WI, USA) on the Maxwell® RSC Instrument, following the manufacturer’s protocol. Library preparation was performed using 100 ng of total RNA

(45) Targeting metabolic vulnerabilities: REV-ERB agonist SR9009 potentiates sorafenib efficacy in liver cancerCell Death DiscoveryJanuary 19, 2026Silvia Sabbioni, Paola Guerriero, Ram C. Shankaraiah, Laura Masatti, Angelo Michilli, Cristian Bassi, Lucilla D’Abundo, Farzaneh Moshiri, Bruno De Siena, Edi Simoni, et al.protein expression. RNA purification Total RNA was extracted from frozen liver cells or tissues using a Maxwell RSC instrument (Promega Italia, Milan) and a Maxwell RSC miRNA from a tissue purification kit (#AS1460, Promega) according

(46) Germline variants in ATM, BRCA2, other cancer predisposition and novel candidate genes are implicated in glioma risk in adult glioma patients with a familial or personal history of tumorsActa NeuropathologicaJanuary 17, 2026Frank Brand, Lily S. Rose, Amir H. Akbarzadeh, Christine A. M. Weber, Isabel Eckert, Gunnar Schmidt, Bernd Auber, Alisa Förster, Ulrike Beyer, Robert Geffers, et al.tumor sections. DNA was extracted using the Maxwell RSC DNA FFPE Kit (Promega, Madison, WI, USA) and a Maxwell RSC Instrument (Promega). For TMB detection, 15 ng tumor DNA was used in an Oncomine Tumor Mutation Load Assay (n =

(47) Molecular Responses to Temperature Changes Across Timescales in the Madagascar Ground Gecko ( Paroedura picta )Molecular EcologyJanuary 17, 2026Fuku Sakamoto, Shunsuke Kanamori, Félix Rakotondraparany, Takashi Makino, Masakado KawataTranscriptome Analysis Total RNA was extracted using the Maxwell RSC Plant RNA Kit and Maxwell RSC Instrument AS4500 (Promega, Madison, WI, USA). RNA concentration and purity were verified using a Nanodrop spectrophotometer

(48) Contrasting whole-genome diversity patterns and adaptation in honeybees from two southern European glacial refugiaiScienceJanuary 16, 2026Carlos A. Yadró Garcia, Dora Henriques, Giovanni Cilia, José Rufino, Cristina Vella, Abdessamad Aglagane, Soledad Sagastume, Marion Zammit-Mangion, Raquel Martín-Hernández, Antonio Nanetti, et al.Italian and 26 A. m. sahariensis samples was extracted from the thorax of individual drones using the Maxwell® RSC Instrument (Promega, USA) with the Maxwell® RSC PureFood GMO and Authentication kit (Promega, USA). To investigate

(49) Statistical and Evolutionary Analysis of Sequenced DNA from Breast Cancer FFPE SpecimensbioRxivJanuary 16, 2026Monika K. Kurpas, Paweł Kuś, Roman Jaksik, Khanh N. Dinh, Agnieszka Adamczyk, Kaja Majchrzyk, Marek KimmelTumor Pathology from macrodissected FFPE tissue samples using a semi-automatic method available from Maxwell® RSC Instrument (Promega) with the settings recommended by the manufacturer. The quality and amount of DNA was evaluated

(50) Polyamine-dependent metabolic shielding regulates alternative splicingNatureJanuary 14, 2026Amaia Zabala-Letona, Mikel Pujana-Vaquerizo, Belen Martinez-Laosa, Maria Ponce-Rodriguez, Saioa Garcia-Longarte, Isabel Mendizabal, Ana Gimeno, Malgorzata Rogalska, Joycelyn Tan, Diana Cabrera, et al.NucleoSpin RNA isolation kit from Macherey-Nagel (ref: 740955.240 C) or automatically extracted using Maxwell RSC instrument (Promega) according to the manufacturers’ instructions (Supplementary Methods). RNA-seq analysis The

(51) Effects of phage-based treatments against an OXA-48-producing Klebsiella pneumoniae isolate in simulated human gut microbiomesBMC MicrobiologyJanuary 8, 2026Celia Ferriol-González, Ana Hernanz-Grimalt, Carlos Valdivia, Silvia García-Cobos, Ana Heredia, Jorge García-Hernández, Ana Andrés, Pilar Domingo-CalapDNA extraction was performed using the Maxwell PureFood GMO and Authentication Kit (Promega) on the Maxwell RSC Instrument (Promega). Quantification of the K. pneumoniae complex was performed by qPCR targeting the zur-khe intergenic

(52) Early-life stages impact later feeding behavior and physiology in light-born pigletsJournal of Animal ScienceJanuary 8, 2026Elizabeth Huenul, Susana M Martín-Orúe, Lluís Fabà, Ruth Forsten, Pau Salgado-López, Ferran Llobet-Cabau, María José Rodríguez-Lagunas, Marta Fornós, José Francisco Pérezobtained using the Maxwell RSC simplyRNA Tissue Kit (Promega Corporation, Madison, WI, United States) in a Maxwell RSC instrument (Promega Corporation, Madison, WI, United States) following the manufacturer’s instructions. The quantity

(53) Targeted next-generation sequencing-based sequencing of cell-free DNA in cerebrospinal fluid uncovers cancer-specific mutations in patients with brain cancer using a widely available panelNeuro-Oncology AdvancesJanuary 7, 2026Alexander Köpp, Peter Westarp, Marta Nowak, Nils Briel, Maximilian Mastall, Adela Brzobohata, Roger Schenk, Michael Schmid, Emilie Le Rhun, Holger Moch, et al.extraction from formalin-fixed paraffin-embedded tissue, the Maxwell RSC DNA FFPE Kit (Promega) on a Maxwell RSC instrument (Promega) was used following the manufacturer’s protocol. Molecular Analysis Liquid biopsy specimens

(54) Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severityeBioMedicineJanuary 6, 2026Claudio Cappadona, Valeria Rimoldi, Francesca Tettamanzi, Giulia Cardamone, Alberto Mantovani, Giulia Soldà, Elvezia Maria Paraboschi, Rosanna AsseltaPromega Maxwell RSC Blood DNA Kit (Promega, Madison, Wisconsin, USA) on a benchtop automated extractor (Maxwell RSC Instrument, RRID:SCR_025867). Library preparation was performed using the SureSelect Human All Exon V7 kit (Agilent Technologies

(55) Epigenetic, histological and clinical characterization of preeclampsia in oocyte donation pregnancies: insights into immune dysregulation and microRNA-mediated pathwaysFrontiers in Cell and Developmental BiologyJanuary 5, 2026Irma Saulle, Maria Di Giminiani, Ozge Yazici, Claudio Fenizia, Manuela Nebuloni, Roberta Rossi, Mara Biasin, Valeria SavasimicroRNA tissue extraction respectively (Promega, Fitchburg, WI, United States) and extracted through the Maxwell® RSC Instrument (Promega, Fitchburg, WI, United States) according to manufacturer’s protocol (Saulle et al., 2023);

(56) Autologous fecal microbiota capsules are safe and potentially preserve beta-cell function in individuals with type 1 diabetesGut MicrobesDecember 31, 2025Pleun de Groen, Coco M. Fuhri Snethlage, Koen Wortelboer, Sevilay Tokgöz, Mark Davids, Xanthe Verdoes, Florine H.M. Westerbeke, Rick I. Meijer, Martin Gotthardt, Willem M. de Vos, et al.protocol, and the purification of the lysates was done using the Maxwell® system (RSC Promega, Cat# AS4500). For both sample types, 300 µL S.T.A.R. buffer (Roche Diagnostics, Cat# 03335208001) was added to the

(57) Liver-specific loss of Atg9a perturbs lipid metabolism and hepatocyte integrityAutophagy ReportsDecember 31, 2025Elodie Mailler, Asmita Singh, Michal Jarnik, Yan Li, Lynne Holtzclaw, Victoria Hoffmann, Sohtaro Mine, Paulina Stallcup, Laleh Ordoubadinia, Carlos M. Guardiagene expression analysis RNA was purified from FFPE sections using the Maxwell RSC RNA FFPE Kit (Promega, AS1440) with the Maxwell RSC Instrument, following the manufacturer’s protocol. Briefly, 3–4 sections (~30 μm thickness) were combined in a

(58) Comparison of two digital PCR platforms for quantification of genetically modified soybean eventsGM Crops & FoodDecember 31, 2025Daniela Verginelli, Sara Ciuffa, Katia Spinella, Davide La Rocca, Daniela Villa, Alessandra Barbante, Elena Perri, Ugo MarchesiUrbana, IL, USA). DNA was extracted from 200 mg of CRMs using the RSC PureFood GMO kit with the extractor Maxwell®RSC Instrument (Promega Madison, WI, USA), according to the manufacturer’s instructions for the Bio-Rad platform and

(59) Performance evaluation of the automated haematology analyzer XN-31 for malaria diagnosis in Plasmodium vivax-dominant regions of ThailandMalaria JournalDecember 29, 2025Miki Kawaguchi, Kanako Komaki-Yasuda, Masami Nakatsu, Nattha Kerdsakundee, Mieko Hamana, Takahiro Tougan, Mina Kamei, Aya Konishi, Srivicha Krudsood, Shigeyuki Kanospecies. PCR DNA was extracted using the Maxwell DNA FFPE Kit (Promega, Madison, WI, USA) and the automated Maxwell RSC Instrument (Promega) from a punched dried blood spot of 5 mm in diameter (approximately equivalent to 20–30 µL

(60) Germline BRCA1/2 Variants in Polish Patients with Family History of Breast and Ovarian Cancer: Prevalence, CNV Detection, and Identification of a Novel Loss-of-Function MutationCurrent OncologyDecember 24, 2025Sebastian Skoczylas, Tomasz Płoszaj, Izabela Dróżdż, Hanna Moczulska, Marcin Serafin, Katarzyna Piekarska, Olga Wojtyczka, Karolina Żeżawska, Agnieszka Zmysłowskatheir informed written consent to genetic testing. DNA was extracted from peripheral blood using the Maxwell® RSC Instrument (Maxwell® RSC Blood DNA Kit, Promega, Madison, WI, USA). Libraries were prepared using the Devyser BRCA

Be the First to Write a Review!