Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(41) Targeted next-generation sequencing-based sequencing of cell-free DNA in cerebrospinal fluid uncovers cancer-specific mutations in patients with brain cancer using a widely available panelNeuro-Oncology AdvancesJanuary 7, 2026Alexander Köpp, Peter Westarp, Marta Nowak, Nils Briel, Maximilian Mastall, Adela Brzobohata, Roger Schenk, Michael Schmid, Emilie Le Rhun, Holger Moch, et al.extraction from formalin-fixed paraffin-embedded tissue, the Maxwell RSC DNA FFPE Kit (Promega) on a Maxwell RSC instrument (Promega) was used following the manufacturer’s protocol. Molecular Analysis Liquid biopsy specimens

(42) Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severityeBioMedicineJanuary 6, 2026Claudio Cappadona, Valeria Rimoldi, Francesca Tettamanzi, Giulia Cardamone, Alberto Mantovani, Giulia Soldà, Elvezia Maria Paraboschi, Rosanna AsseltaPromega Maxwell RSC Blood DNA Kit (Promega, Madison, Wisconsin, USA) on a benchtop automated extractor (Maxwell RSC Instrument, RRID:SCR_025867). Library preparation was performed using the SureSelect Human All Exon V7 kit (Agilent Technologies

(43) Epigenetic, histological and clinical characterization of preeclampsia in oocyte donation pregnancies: insights into immune dysregulation and microRNA-mediated pathwaysFrontiers in Cell and Developmental BiologyJanuary 5, 2026Irma Saulle, Maria Di Giminiani, Ozge Yazici, Claudio Fenizia, Manuela Nebuloni, Roberta Rossi, Mara Biasin, Valeria SavasimicroRNA tissue extraction respectively (Promega, Fitchburg, WI, United States) and extracted through the Maxwell® RSC Instrument (Promega, Fitchburg, WI, United States) according to manufacturer’s protocol (Saulle et al., 2023);

(44) Liver-specific loss of Atg9a perturbs lipid metabolism and hepatocyte integrityAutophagy ReportsDecember 31, 2025Elodie Mailler, Asmita Singh, Michal Jarnik, Yan Li, Lynne Holtzclaw, Victoria Hoffmann, Sohtaro Mine, Paulina Stallcup, Laleh Ordoubadinia, Carlos M. Guardiagene expression analysis RNA was purified from FFPE sections using the Maxwell RSC RNA FFPE Kit (Promega, AS1440) with the Maxwell RSC Instrument, following the manufacturer’s protocol. Briefly, 3–4 sections (~30 μm thickness) were combined in a

(45) Autologous fecal microbiota capsules are safe and potentially preserve beta-cell function in individuals with type 1 diabetesGut MicrobesDecember 31, 2025Pleun de Groen, Coco M. Fuhri Snethlage, Koen Wortelboer, Sevilay Tokgöz, Mark Davids, Xanthe Verdoes, Florine H.M. Westerbeke, Rick I. Meijer, Martin Gotthardt, Willem M. de Vos, et al.protocol, and the purification of the lysates was done using the Maxwell® system (RSC Promega, Cat# AS4500). For both sample types, 300 µL S.T.A.R. buffer (Roche Diagnostics, Cat# 03335208001) was added to the

(46) Comparison of two digital PCR platforms for quantification of genetically modified soybean eventsGM Crops & FoodDecember 31, 2025Daniela Verginelli, Sara Ciuffa, Katia Spinella, Davide La Rocca, Daniela Villa, Alessandra Barbante, Elena Perri, Ugo MarchesiUrbana, IL, USA). DNA was extracted from 200 mg of CRMs using the RSC PureFood GMO kit with the extractor Maxwell®RSC Instrument (Promega Madison, WI, USA), according to the manufacturer’s instructions for the Bio-Rad platform and

(47) Performance evaluation of the automated haematology analyzer XN-31 for malaria diagnosis in Plasmodium vivax-dominant regions of ThailandMalaria JournalDecember 29, 2025Miki Kawaguchi, Kanako Komaki-Yasuda, Masami Nakatsu, Nattha Kerdsakundee, Mieko Hamana, Takahiro Tougan, Mina Kamei, Aya Konishi, Srivicha Krudsood, Shigeyuki Kanospecies. PCR DNA was extracted using the Maxwell DNA FFPE Kit (Promega, Madison, WI, USA) and the automated Maxwell RSC Instrument (Promega) from a punched dried blood spot of 5 mm in diameter (approximately equivalent to 20–30 µL

(48) Germline BRCA1/2 Variants in Polish Patients with Family History of Breast and Ovarian Cancer: Prevalence, CNV Detection, and Identification of a Novel Loss-of-Function MutationCurrent OncologyDecember 24, 2025Sebastian Skoczylas, Tomasz Płoszaj, Izabela Dróżdż, Hanna Moczulska, Marcin Serafin, Katarzyna Piekarska, Olga Wojtyczka, Karolina Żeżawska, Agnieszka Zmysłowskatheir informed written consent to genetic testing. DNA was extracted from peripheral blood using the Maxwell® RSC Instrument (Maxwell® RSC Blood DNA Kit, Promega, Madison, WI, USA). Libraries were prepared using the Devyser BRCA

(49) Centriflaken: An automated data analysis pipeline for assembly and in silico analyses of foodborne pathogens from metagenomic samplesPLoS OneDecember 23, 2025Kranti Konganti, Julie A. Kase, Narjol Gonzalez-Escalonaenriched agricultural water sample was extracted using the Maxwell RSC Cultured Cell DNA Kit with a Maxwell RSC Instrument (Promega Corporation, Madison, WI, USA) according to the manufacturer’s instructions DNA concentration

(50) Claudin‐18 expression in gastric type adenocarcinoma and HPV ‐associated adenocarcinoma of the uterine cervixHistopathologyDecember 22, 2025Nobuko Yasutake, Yuki Yokawa, Takehiro Tanaka, Riri Mishima, Misato Komamizu, Ryosuke Kuga, Rina Jiromaru, Shinichiro Kawatoko, Kenzo Sonoda, Hideaki Yahata, et al.CLDN18.2 mRNA Expression Total RNA was extracted from FFPE samples using a Maxwell® RSC RNA FFPE Kit and Maxwell® RSC Instrument (Promega Corporation, Madison, WI, USA) according to the manufacturer's protocol. RNA concentrations

(51) Variant analysis and biochemical investigation in two siblings with late onset idiopathic secondary erythrocytosis: A case reportMedicine (Baltimore)December 19, 2025Vincenza Ylenia Cusenza, Beatrice Melli, Chiara Marraccini, Agnese Razzoli, Margherita Genitoni, Laura Albertazzi, Nesrine Gamal, Gaia Gavioli, Davide Nicoli, Enrico Farnetti, et al.peripheral blood sample using the Maxwell® 16 LEV Blood DNA kit (Maxwell® 16 LEV Blood DNA Kit) on the Maxwell® RSC instrument (Promega Corporation, Madison), according to the manufacturer’s specifications. DNA amplification by

(52) Genome and transcriptome-wide association studies identify multiple novel loci for dementia with grain in JapaneseJournal of Human GeneticsDecember 17, 2025Risa Mitsumori, Kouichi Ozaki, Yuko Saito, Daichi Shigemizu, Atsushi Iwata, Shigeo Murayama, Masahiro Akishita, Tomio Arai, Shumpei Niida, Kenji TobaDNA from NCGG biobank was extracted from peripheral blood leukocytes by standard protocols using a Maxwell RSC Instrument and a Maxwell RSC Buffy Coat DNA Kit (Promega, Madison, WI, USA). Genomic DNA from TMIG was extracted

(53) Effects of Long-Term Ocean Acidification Exposure on the Structural, Mineralogical, and Mechanical Properties of Sea Urchin (Echinometra spp.) Skeletons at a Natural Volcanic CO2 SeepEnviron Sci TechnolDecember 16, 2025Callum J. Hudson, Jeffrey Jolly, Sean D. Connell, Timothy Ravasi, Ben P. Harveyextracted from the tissue using Promega Maxwell RSC Tissue DNA Kits (Promega, USA) and the associated Maxwell RSC Instrument according to the manufacturer’s protocols. The extracted DNA concentration was measured by fluorometry

(54) Identification of Intronic Variants in NDUFA3 as a Cause of Leigh Syndrome by Whole Genome Sequencing and RNA SequencingNeurol GenetDecember 11, 2025Kohta Nakamura, Yoshihito Kishita, Ayumu Sugiura, Kokoro Ozaki, Yukiko Yatsuka, Naoyuki Matsumoto, Atsuko Okazaki, Holger Prokisch, Koichi Maruyama, Hiroyasu Iwasa, et al.RNA Sequencing RNA was purified from patient-derived skin fibroblasts by the Maxwell RSC simplyRNA Cells Kit and a Maxwell RSC Instrument (Promega). mRNA was enriched using oligo (dT) beads and rRNA removed using the Illumina Ribo-Zero kit.

(55) Replicon-based genome-wide CRISPR knockout screening for the identification of host factors involved in viral replicationNat CommunDecember 10, 2025Karen W. Cheng, Madhura Bhave, Andrew L. Markhard, Duo Peng, Karan D. Bhatt, Katherine A. Travisano, Josette V. Medicielo, Astrid Anaya, Sanae Lembirik, Leila Njoya, et al.Maxwell RSC Viral Total Nucleic Acid Purification Kit (Promega, AS1330) and the automated Maxwell RSC extractor (Promega, AS4500). Briefly, 200 µL of TRIzol LS-treated sample were added to 200 µL of the kit’s lysis buffer and vortexed

(56) A phage displaying an Aβ-interacting peptide mitigates neurotoxicity and prevents Aβ-driven gene expression changesFront Mol NeurosciDecember 10, 2025Laura Maria De Plano, Luigi Chiricosta, Simone D'Angiolini, Alessandra Saitta, Alessandra Trainito, Serena Silvestro, Sabrina Conoci, Salvatore Oddo, Antonella Caccamoof 12CIII1. Following treatment, cell pellets were collected, and total RNA was extracted using the Maxwell® RSC instrument according to the manufacturer’s instructions for the Maxwell® RSC simplyRNA Cells Kit (Promega, Madison,

(57) Induction of immune education in type 1 diabetes through controlled allogeneic islet rejection at onset: a monocentric open-label pilot studyEClinicalMedicineDecember 4, 2025Lorenzo Piemonti, Andrea Mario Bolla, Amelia Caretto, Raffaella Melzi, Alessia Mercalli, Valeria Sordi, Paolo Monti, Paola Magistretti, Vito Lampasona, Ilaria Marzinotto, et al.12, 18 months; and 2, 3, 4, 5 years) using the Maxwell® RSC miRNA from Plasma and Serum kit with the Maxwell® RSC Instrument (Promega), according to manufacturer's instructions. All serum miRNAs underwent universal reverse transcription

(58) Soil phosphate availability drives shifts between arbuscular mycorrhizal and ectomycorrhizal fungi in the dual mycorrhizal plant Quercus serrataNew PhytologistDecember 1, 2025Tatsuhiro Ezawa, Chika Mizukami, Anjar Cahyaningtyas, Mana Mukai, Kanehiro KitayamaMulti‐Beads Shocker (Yasui Kikai), and DNA was extracted and purified from c. 100 mg FW of ground sample by Maxwell RSC Instrument using Maxwell RSC PureFood GMO and Authentication Kit (Promega, Tokyo, Japan) according to the manufacturer's

(59) Infection Dynamics and Host Biomarker Identification for Spotty Liver Disease in ChickensVet SciNovember 29, 2025Helen James, Emily Gan, Robert J. Moore, Daniel M. Andrews, Thi Thu Hao Vanwith C. hepaticus-specific primers as described by Van et al. 2017 [24]. DNA was extracted using the Maxwell® RSC instrument with the Maxwell® RSC PureFood GMO and Authentication Kit (Promega, Madison, WI, USA), following the

(60) Efficacy of nutraceutical supplements containing Passiflora incarnata L., Withania somnifera (L.) Dunal and Taraxacum officinale (L.) weber ex F.H.Wigg. on markers of inflammation, oxidative stress and gut microbiota in senior dogsFrontiers in Veterinary ScienceNovember 27, 2025Roberto Ciarcia, Consiglia Longobardi, Valeria Iervolino, Tommaso Manenti, Francesco Ferrucci, Iolanda Veneruso, Valeria D’Argenio, Antonio Rubino, Alessandra Pelagalli, Pietro Lombardi, et al.h, frozen at −80 °C until analysis. Genomic DNAs were obtained using the RSC Blood DNA kit and the Maxwell RSC instrument (both from Promega, Madison, WI, USA), as previously reported (26). Two blank/negative samples were

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