Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(21) Parasitic surveillance in wolves of central Italy: a focus on the Abruzzo regionParasites & VectorsFebruary 21, 2026Sabrina Vanessa Patrizia Defourny, Mariasole Colombo, Gianluca D’Amico, Stefania Salucci, Antonio Cocco, Maria Chiara Cantelmi, Daniela Averaimo, Marco Rulli, Gianfranco Romeo, Susanna Tora, et al.min. DNA was extracted from the sediment using the standardized lysis and purification protocol of the Maxwell RSC® Instrument Genomic Kit (Promega, Madison, WI, USA). DNA was analyzed by real-time PCR (qPCR) [23] to detect Leishmania

(22) Detection of structural DNA variants in medulloblastomas using optical genome mappingActa Neuropathologica CommunicationsFebruary 11, 2026Nadezhda Kubon, Mirela Bălan, David Koppstein, Sophia Praeger, Marietta Wolter, Peter Ebert, David Pauck, Jörg Felsberg, Thomas Beez, Daniel Picard, et al.extracted from fresh-frozen MB tissue samples (n = 29) using the Maxwell® RSC simplyRNA Tissue Kit and Maxwell® RSC Instrument (Promega). RNA sequencing libraries were prepared either with the Illumina Stranded Total RNA Prep,

(23) Enhanced virulence of mpox virus clade Ib over clade IIb in the CAST/EiJ mouse modelCommunications BiologyFebruary 11, 2026Alazne R. Unanue, Rocío Martín, Carolina Sánchez, Isabel Alonso-Sánchez, Ana Moraga-Quintanilla, Laura Fernandez del Ama, Pedro J. Sánchez-Cordón, Antonio Alcamí, Bruno HernáezDNA was isolated from homogenized MPXV infected organs using Maxwell RSC Viral TNA kit (Promega) and Maxwell RSC instrument (Promega) and finally eluted in 50 μl nuclease free water. We set up a multiplex RT-qPCR to detect viral

(24) Rapid Drug Sensitivity Profiling via a Novel High-Success-Rate Culture Method for Patient-Derived Pancreatic Cancer: An Exploratory Preclinical Platform for Advancing Clinical Applications and Drug DevelopmentCellsFebruary 7, 2026Yu Kato, Naoki Yamamoto, Yuichiro Uchida, Noriko Hiramatsu, Takato Ozeki, Yukari Minobe, Yukika Hasegawa, Sho Kawabe, Hikaru Yabuuchi, Seiji Yamada, et al.passage) using Maxwell® RSC Cultured Cell DNA Kit (Cat No. AS1620; Promega, Madison, WI, USA) with a Maxwell® RSC Instrument according to the manufacturer’s instructions. DNA concentration was quantified using a Quantus Fluorometer

(25) Strawberry atlas: Fragaria vesca gene expression atlas for strawberry genomicsPeerJFebruary 5, 2026Minto Odagiri, Chonprakun Thagun, Takeshi Kurokura, Tomohiro Suzuki, Yutaka Kodama, Yoshinori Fukasawaexpression Total RNA was extracted from each tissue using the Maxwell RSC Plant RNA kit together with the Maxwell RSC instrument (Promega, Madison, WI, USA) according to the manufacturer’s instructions. Extracted RNA was quantified

(26) Enhancing the accuracy of molecular classification of pediatric CNS tumors: a dual-classifier approach using DNA methylation profilingFrontiers in OncologyFebruary 5, 2026Esra Moosa, Rania Alanany, Shimaa Sherif, Erdener Ozer, Sukoluhle Dube, Aayesha Jabeen, Apryl Sanchez, Asma Jamil, Aisha Khalifa, Chiara Cugno, et al.(#69504, Qiagen) or the Maxwell® RSC Tissue DNA Kit (AS1610, Promega) on the Maxwell RSC instrument (AS4500, Promega) following the manufacturers’ protocols. Two pathologists (W.M. and E.O.) and one research

(27) Cytoplasmic poly-adenosine binding proteins modulate susceptibility of mRNAs to Pumilio-mediated decayNucleic Acids ResFebruary 5, 2026Katherine M McKenney, Carmen Hernandez-Perez, Elise B Dunshee, John M Pum, Anna J DesMarais, Robert P Connacher, Aaron C Goldstrohmfor 5 min. RNA was purified from the cell pellet using the SimplyRNA Cells kit (Promega, AS1390) and Maxwell RSC instrument following the manufacturer’s protocol. For the on-bead DNase digestion, the amount of DNase I (Promega,

(28) GJB6 missense variant in a Labrador Retriever with paw pad hyperkeratosisAnimal GeneticsFebruary 1, 2026Stefan J. Rietmann, Joseph Malatos, Vidhya Jagannathan, Tosso Leebwhole genome sequencing Genomic DNA was extracted from EDTA‐whole blood samples. The extraction was performed with a Maxwell™ RSC instrument using the Maxwell RSC Whole Blood DNA Kit (Promega, Dübendorf, Switzerland). For whole genome sequencing

(29) Basal cell adenoma with S100 protein–positive “stroma”: a distinct triphasic salivary gland neoplasm characterized by CTNNB1 mutationVirchows ArchivFebruary 1, 2026Alena Skálová, Martina Bradová, Jan Laco, Tomáš Vaněček, Veronika Hájková, Petr Martínek, Marián Grendár, Giulia Querzoli, Ilmo Leivo, Michal Michal(Thermo Fisher Scientific, Waltham, MA). RNA was extracted using the Maxwell RSC DNA FFPE Kit and the Maxwell RSC Instrument (Promega, Madison, WI) according to the manufacturer’s instructions and quantified using the Qubit HS

(30) Methylation-specific, universal, and highly sensitive identification of ctDNA in prostate cancer by multiplex droplet digital PCRPLOS OneJanuary 29, 2026Søren Kahns, Ahmed H. Zedan, Mads M. Aagaard, Luisa M. D. Canto, Sanne Kjær-Frifeldt, Stine V. Eriksen, Christine V. Madsen, Jonna S. Madsen, Palle J. S. Osther, Torben F. Hansen, et al.mCRPC. Extraction of DNA from tissue, whole blood, and plasma DNA was extracted from FFPE biopsy specimens on the Maxwell RSC instrument using the Maxwell RSC FFPE Plus DNA Kit (Promega, Madison, WI, USA) according to the manufacturer’s

(31) Association between histogram parameters of T2 weighted MRI data, WHO grade, tumor proliferation index and selected molecular markers in low-grade gliomaFrontiers in RadiologyJanuary 29, 2026Georg Gihr, Hans Henkes, Ali Khanafer, Mehdi Allouche, Oliver Ganslandt, Sebastian Johannes Müller, Walter Alexander Wohlgemuth, Stefan Schobparaffin-embedded tissue blocks using the Maxwell® RSC FFPE Plus DNA Kit AS1720 (Promega, Madison, WI, USA) and the Maxwell® RSC Instrument (Promega). The isolated DNA underwent bisulfite treatment using the EpiTect® Bisulfite Kit (QIAGEN,

(32) Surveillance of avian influenza viruses in migratory wild birds in South Korea, 2019–2025Journal of Veterinary ScienceJanuary 26, 2026Jae Kyung Lee, Min Beom Kim, Seo Hyeon Kim, Song Hwi Jeong, HaanWoo Sung, Hyung-Kwan Jang, Kang-Seuk Choi, Daesung Yoo, Se-Hee An, Gyeong-Beom Heo, et al.described [17]. Briefly, Viral RNA was directly extracted from pooled fecal supernatant sample using the Maxwell RSC instrument with Maxwell RSC simplyRNA Tissue Kit (Promega, Korea), and AI virus matrix (M), H5, and H7 real-time

(33) PCB 153 Modulates Genes Involved in Proteasome and Neurodegeneration-Related Pathways in Differentiated SH-SY5Y Cells: A Transcriptomic StudyCellsJanuary 23, 2026Aurelio Minuti, Serena Silvestro, Claudia Muscarà, Michele Scuruchi, Simone D’AngioliniRNA was then extracted using the Maxwell® RSC simplyRNA Cells Kit (Promega, Madison, WI, USA) on the Maxwell® RSC Instrument, following the manufacturer’s protocol. Library preparation was performed using 100 ng of total RNA

(34) Targeting metabolic vulnerabilities: REV-ERB agonist SR9009 potentiates sorafenib efficacy in liver cancerCell Death DiscoveryJanuary 19, 2026Silvia Sabbioni, Paola Guerriero, Ram C. Shankaraiah, Laura Masatti, Angelo Michilli, Cristian Bassi, Lucilla D’Abundo, Farzaneh Moshiri, Bruno De Siena, Edi Simoni, et al.protein expression. RNA purification Total RNA was extracted from frozen liver cells or tissues using a Maxwell RSC instrument (Promega Italia, Milan) and a Maxwell RSC miRNA from a tissue purification kit (#AS1460, Promega) according

(35) Molecular Responses to Temperature Changes Across Timescales in the Madagascar Ground Gecko ( Paroedura picta )Molecular EcologyJanuary 17, 2026Fuku Sakamoto, Shunsuke Kanamori, Félix Rakotondraparany, Takashi Makino, Masakado KawataTranscriptome Analysis Total RNA was extracted using the Maxwell RSC Plant RNA Kit and Maxwell RSC Instrument AS4500 (Promega, Madison, WI, USA). RNA concentration and purity were verified using a Nanodrop spectrophotometer

(36) Germline variants in ATM, BRCA2, other cancer predisposition and novel candidate genes are implicated in glioma risk in adult glioma patients with a familial or personal history of tumorsActa NeuropathologicaJanuary 17, 2026Frank Brand, Lily S. Rose, Amir H. Akbarzadeh, Christine A. M. Weber, Isabel Eckert, Gunnar Schmidt, Bernd Auber, Alisa Förster, Ulrike Beyer, Robert Geffers, et al.tumor sections. DNA was extracted using the Maxwell RSC DNA FFPE Kit (Promega, Madison, WI, USA) and a Maxwell RSC Instrument (Promega). For TMB detection, 15 ng tumor DNA was used in an Oncomine Tumor Mutation Load Assay (n =

(37) Contrasting whole-genome diversity patterns and adaptation in honeybees from two southern European glacial refugiaiScienceJanuary 16, 2026Carlos A. Yadró Garcia, Dora Henriques, Giovanni Cilia, José Rufino, Cristina Vella, Abdessamad Aglagane, Soledad Sagastume, Marion Zammit-Mangion, Raquel Martín-Hernández, Antonio Nanetti, et al.Italian and 26 A. m. sahariensis samples was extracted from the thorax of individual drones using the Maxwell® RSC Instrument (Promega, USA) with the Maxwell® RSC PureFood GMO and Authentication kit (Promega, USA). To investigate

(38) Polyamine-dependent metabolic shielding regulates alternative splicingNatureJanuary 14, 2026Amaia Zabala-Letona, Mikel Pujana-Vaquerizo, Belen Martinez-Laosa, Maria Ponce-Rodriguez, Saioa Garcia-Longarte, Isabel Mendizabal, Ana Gimeno, Malgorzata Rogalska, Joycelyn Tan, Diana Cabrera, et al.NucleoSpin RNA isolation kit from Macherey-Nagel (ref: 740955.240 C) or automatically extracted using Maxwell RSC instrument (Promega) according to the manufacturers’ instructions (Supplementary Methods). RNA-seq analysis The

(39) Early-life stages impact later feeding behavior and physiology in light-born pigletsJournal of Animal ScienceJanuary 8, 2026Elizabeth Huenul, Susana M Martín-Orúe, Lluís Fabà, Ruth Forsten, Pau Salgado-López, Ferran Llobet-Cabau, María José Rodríguez-Lagunas, Marta Fornós, José Francisco Pérezobtained using the Maxwell RSC simplyRNA Tissue Kit (Promega Corporation, Madison, WI, United States) in a Maxwell RSC instrument (Promega Corporation, Madison, WI, United States) following the manufacturer’s instructions. The quantity

(40) Effects of phage-based treatments against an OXA-48-producing Klebsiella pneumoniae isolate in simulated human gut microbiomesBMC MicrobiologyJanuary 8, 2026Celia Ferriol-González, Ana Hernanz-Grimalt, Carlos Valdivia, Silvia García-Cobos, Ana Heredia, Jorge García-Hernández, Ana Andrés, Pilar Domingo-CalapDNA extraction was performed using the Maxwell PureFood GMO and Authentication Kit (Promega) on the Maxwell RSC Instrument (Promega). Quantification of the K. pneumoniae complex was performed by qPCR targeting the zur-khe intergenic

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