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Automated DNA/RNA Purification Sample Preparation Workstations
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
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Citations:
(881)
Figures:
(1)
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Promega for
Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV Lamp
Avg. lifetime approximately 6,000 hrs
Molecular Weight
~85kDa
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (881)
(21)
Phenotypic heterogeneity shapes phage resistance and cocktail efficacy in Klebsiella pneumoniae
Microbiology Spectrum
June 2, 2026
Lucas Mora-Quilis, Rafael Sanjuán, Pilar Domingo-Calap
concentrated lysate was used to extract DNA from viral capsids using an automated protocol with the
Maxwell RSC Instrument
(
Promega
). DNA libraries were generated using the Illumina Nextera XT DNA kit (2 × 150 bp or 2 × 250
(22)
Functional Characterization of a Novel Homozygous DNAH5 Single-Nucleotide Intronic Deletion in a Consanguineous Portuguese Family with Primary Ciliary Dyskinesia
Cells
June 2, 2026
Catarina Hilário, Sara Raimundo, Catarina Dias, Joana Saramago, Telma Oliveira, Rute Pereira, Sofia Quental, João Parente Freixo, Luís Gales, Jorge Oliveira,
et al.
were immediately immersed in RNAlater (Thermo Fisher Scientific), and total RNA was isolated using the
Maxwell® RSC Instrument
and the
Maxwell® RSC simplyRNA Tissue Kit
(
Promega
, Madison, WI, USA), following the manufacturer’s
(23)
Performance of Seven-Gene Panel Testing for Risk Stratification of Thyroid Nodules with Indeterminate Cytology Results
Int J Mol Sci
May 30, 2026
Ann-Kristin Jochum, Frida Renström, Barbara Bischofberger-Baumann, Izadora Demmer, René Schönegg, Michael Brändle, Stefan Bilz, Wolfram Jochum
FNA material was available. Total nucleic acids were extracted from liquid-based FNA samples using a
Maxwell RSC instrument
(
Promega
, Madison, WI, USA) with the
Maxwell RSC Viral Total Nucleic Acid Purification Kit
(
Promega
)
(24)
A guide for establishing patient-derived organoids from bile samples obtained during endoscopic procedures and performing gene expression knockdown
Frontiers in Cell and Developmental Biology
May 29, 2026
Carla Rojo, Juan J. Vila, Laura Guembe, Amaia Arrubla-Gamboa, Vanesa Jusué-Irurita, Juan Carrascosa-Gil, María Rullan, Javier Rández-Garbayo, Maite G. Fernández-Barrena, Meritxell Huch,
et al.
the final
centrifugation
step (prior to Matrigel re-embedding).RNA is extracted using the automated
Maxwell RSC Instrument
with the Maxwell RSC simply RNA Tissue kit (
Promega
, Madison, WI, United States of America) following
(25)
Deciphering macrophage molecular responses to Porphyromonas gingivalis outer membrane vesicles through combined immunoassay and Raman spectroscopic analyses
Frontiers in Microbiology
May 29, 2026
Yoshiyuki Matsuo, Aoi Son, Sara Gentile, Riccardo Bernola, Takashi Yamashita, Saki Ikegami, Lucia Sileo, Luna Ardondi, Toru Kariu, Barbara Zavan,
et al.
IFN-γ (0.02 μg/mL) for 16 h. Total RNA was extracted using the
Maxwell RSC simplyRNA Cells Kit
and the
Maxwell RSC Instrument
(
Promega
, Co., Madison, WI, United States). One microgram of total RNA was reverse transcribed into
(26)
Cuproptosis inducers mediate cold lethality via SLCR-46.1 in C. elegans
Nat Commun
May 27, 2026
Serina Yamashiro, Satomi Mizuno, Haruka Motomura, Aidan T. Pezacki, Yukina Mori, Christopher J. Chang, Akane Ohta, Atsushi Kuhara
using the Maxwell RSC Simply RNA Tissue Kit (
Promega
;
AS1340
) and the
Maxwell RSC Instrument
(
Promega
;
AS4500
), following the manufacturer’s instructions.
Sequencing
libraries were prepared with the TruSeq Stranded
(27)
Method optimization of protein and nucleic acid extraction from skin tape strip samples for biomarker analysis
Frontiers in Medicine
May 25, 2026
Erika L. Boarder, Jessica L. Moore, Kyra A. Richardson, Angelina Volkova, Danielle Guttierez, Cynthia D. Timmers, Susan H. Smith
(Qiagen, RNeasy Mini Kit, Hilden, Germany), (b) automated bead-based extraction and
purification
using the
Maxwell RSC Instrument
(
Promega
, Madison, WI, United States), or (c) lysis in Buffer RLT, containing guanidine thiocyanate,
(28)
Circulating Tumor DNA and microRNA–Based Liquid Biopsy for Longitudinal Treatment Monitoring and Recurrence Prediction in Pediatric Sarcomas: A Prospective Cohort Study
Oncology Research
May 21, 2026
Maher Kurdi, Amber Hassan, Bashar Reda, Anas Nooh, Mohammed Alsobaie, Alaa Alkhotani, Dahlia S. Mirdad, Majid Almansouri, Khalid Khashoggi, Manal Halwani,
et al.
using the
Maxwell RSC miRNA Plasma and Serum Kit
(Cat. No.
AS1680
,
Promega
, Madison, WI, USA) on the
Maxwell RSC Instrument
, in accordance with the manufacturer’s instructions. Total RNA concentration was quantified using the
(29)
Streptococcus agalactiae Serotype Ia ST7 CC1 in Farmed Nile Tilapia in Latin America: Age-Dependent Disease Expression and Antimicrobial Susceptibility of an Emerging Clonal Lineage
Pathogens
May 18, 2026
Marco Rozas-Serri, Miguel Fernandez-Alarcon, Mariene Miyoko-Natori, Renata Galetti, Ricardo Harakava, Mateus Cardoso-Guimarães, Ricardo Ildefonso
manufacturer’s instructions. Bacterial genomic DNA was then semi-automatically extracted using the
Maxwell® RSC instrument
for the RSC Genomic DNA Kit (
Promega Corporation
, Madison, WI, USA) according to the manufacturer’s
(30)
USP29 ‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer
Molecular Oncology
May 13, 2026
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés,
et al.
quantify the wounded area. 2.6 RNA isolation and
RT‐qPCR
Total RNA was automatically extracted using
Maxwell® RSC instrument
and
Maxwell RSC simplyRNA Cells Kit
(
Promega
) according to the manufacturers' instructions. RNA concentration
(31)
Evaluating fecal inflammation biomarkers for non-invasive detection of weaning-related intestinal inflammation in piglets
J Anim Sci
May 9, 2026
Júlia Suppi, Eudald Llauradó-Calero, Jaume Coma, Anna Pelegrí-Pineda, Yolanda Saco, Anna Bassols, David Solà-Oriol
RNA was performed using
Maxwell® RSC simplyRNA Tissue Kit
(
Promega Corporation
, Madison, WI, US) in a
Maxwell ® RSC instrument
(
Promega Corporation
, Madison, WI, US). Quantification of total RNA was carried out in a NanoDrop ND-1000
(32)
Chloroplast stress caused by maltose hyperaccumulation activates chlorophagy via the core autophagy machinery
Plant Physiol
May 8, 2026
Sakuya Nakamura, Mayumi Wakazaki, Mayuko Sato, Kiminori Toyooka, Atsushi J Nagano, Hiroyuki Ishida, Shinya Hagihara, Masanori Izumi
shown.
RT-qPCR
Total RNA was isolated from rosette leaves using a
Maxwell RSC Plant RNA Kit
(
Promega
) and a
Maxwell RSC instrument
(
Promega
). The third rosette leaves from 2 plants were pooled as a sample. Equal amounts of total RNA
(33)
Globodera pallida virulence on major potato resistance has a common genetic basis across Western Europe
PLoS Pathog
May 6, 2026
Arno S. Schaveling, Leidy van Rijt, Yoonseon Do, Nike Soffree, Daan Langendoen, Hilde Room, André Machado Bertran, Margien Raven, Sebastiaan P. van Kessel, Evelyn Y.J. van Heese,
et al.
DNA was extracted using the
Maxwell RSC PureFood GMO and Authentication Kit
in combination with the
Maxwell RSC instrument
(
Promega
, USA) following the manufacturer’s instructions. This yielded between 4.1 and 11.3 ng/ μL of
(34)
Evaluating Viral Pollution in Wastewater and Mediterranean Ecosystems
Food Environ Virol
April 29, 2026
Pablo Puchades-Colera, Inés Girón-Guzmán, Enric Cuevas-Ferrando, Azahara Díaz-Reolid, Irene Falcó, Rosa Aznar, Marinella Farré, Marta Llorca, Alba Pérez-Cataluña, Gloria Sánchez
concentrates (300 µL), as well as from biosolids and sediment suspensions (300 µL), was performed using the
Maxwell® RSC Instrument
(
Promega
, Madison, USA) in combination with the Maxwell RSC Pure Food GMO and authentication kit, following
(35)
In cold blood: screening wild Alaskan moose (Alces alces gigas) for filarial nematode (Filarioidea: Onchocercidae) infections using a deep-amplicon sequencing approach
Parasitology
April 20, 2026
Matthew R. Kulpa, John A. Crouse, Daniel P. Thompson, Joe L. Luksovsky, John C. Blazier, John S. Gilleard, Guilherme G. Verocai
thermomixer at 300 rpm for 30 minutes. Once complete, 200 μL of each sample was aliquoted and placed into a
Maxwell® RSC Instrument
(
Promega Corporation
, Madison, WI, USA) for automated DNA extraction using a
Maxwell® RSC Tissue DNA Kit
(36)
Extracellular Vesicle-Associated miR-222-3p and miR-186-5p as Potential Hypoxic Markers in Canine Osteosarcoma: A Preliminary In Vitro Study
Animals (Basel)
April 20, 2026
Raffaella De Maria, Manuela Poncina, Sara Divari, Lorenza Parisi, Sonia Capellero, Luiza Cesar Conti, Eugenio Mazzone, Federica Fratini, Luca Aresu, Lorella Maniscalco
No.
AS1680
, Madison, WI, USA) according to the manufacturer’s instructions, employing the automated
Maxwell® RSC instrument
(
Promega
, Madison, WI, USA) to ensure consistent yield and minimize manual handling.
MiRNA
concentration
(37)
Dietary 1.3-1.6 yeast β-glucans enhance immune response and disease resilience in European seabass challenged with Tenacibaculum maritimum
Frontiers in Immunology
April 20, 2026
Miguel Cabano, Nadège Richard, Julie Schulthess, Lourenço Ramos-Pinto, Francisco Pinto-Cunha, Maria João Peixoto, Cláudia Aragão, Benjamin Costas
was extracted from posterior gut and skin tissues (n = 16, per diet ×
infection
condition) using the
Maxwell® RSC Instrument
(
Promega
, USA) and the
Maxwell® RSC simplyRNA Tissue Kit
, following the manufacturer’s instructions.
(38)
Antagonism by the type VI secretion system of Bacteroides fragilis is controlled by a TetR family regulator and released small molecule
Proceedings of the National Academy of Sciences
April 14, 2026
Leila Tuzlak, Téa E. Pappas, Michael J. Coyne, Madeline L. Sheahan, Victoria Burgo, Phoebe A. Rice, Laurie E. Comstock
DNAse treatment and elution. Nucleic acid was recovered from broth grown bacterial cultures using the
Maxwell RSC instrument
(
Promega Corporation
, Madison, WI). RNA was quantified using QubitFlex (Life Technologies) and integrity
(39)
Validation of a Duplex Digital PCR Assay for the Quantification of the NK603 Maize Event Across Three dPCR Platforms
Foods
April 14, 2026
Daniela Verginelli, Katia Spinella, Sara Ciuffa, Raffaele Carrano, Davide La Rocca, Elisa Pierboni, Monica Borghi, Silvana Farneti, Ugo Marchesi
starting from 200 mg of CRMs was performed using the Maxwell® RSC PureFood GMO extraction method with the
Maxwell® RSC Instrument
(
Promega Corporation
, Madison, WI, USA), according to the manufacturer’s instructions, for the Bio-Rad
(40)
Molecular Sex Determination in Caenophidian Snakes Using qPCR Amplification of Sex-Linked Genes: Validation and Interspecific Comparison
Animals (Basel)
April 11, 2026
George Iulian Enacrachi, Anamaria Ioana Paştiu, Dana Liana Pusta
dorsal trunk region of the exuvium (Figure 2) to standardize sampling across individuals, using the
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA) and the
Maxwell® RSC Genomic DNA Kit
(
Promega
, USA), following the manufacturer’s
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Maxwell RSC Instrument from Promega
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