Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(21) Genetic variants associated with clinical characteristics and atopies in eosinophilic esophagitisJournal of Allergy and Clinical Immunology: GlobalSeptember 1, 2026Leticia Rodríguez-Alcolado, Marcos Navares-Gómez, Sergio Casabona-Francés, Javier Molina-Infante, Danila Guagnozzi, Paula Soria-Chacartegui, Sara Feo-Ortega, Laura Arias-González, Macarena Torres-Larrubia, Ronald Llerena-Castro, et al.subcohorts. Genotyping DNA extraction was performed using the Maxwell RSC Whole Blood DNA kit (Promega, Madison, Wis) in a Maxwell RSC instrument (Promega) following the manufacturer’s instructions. Genotyping was performed using the QuantStudio 12K Flex Real-Time PCR System

(22) Unrecognized mitochondrial diabetes cases in a group of patients with type 2 diabetesActa DiabetologicaAugust 24, 2026Sebastian Skoczylas, Tomasz Płoszaj, Natalia Kapelan, Julia Grzybowska-Adamowicz, Katarzyna Piekarska, Julia Gonciarz, Katarzyna Nalepa, Ewa Zmysłowska-Polakowska, Maciej Borowiec, Katarzyna Cypryk, et al.centrifuged at 3000 g for 10 min at room temperature. Total DNA was extracted from the cell pellet using a Maxwell® RSC Instrument (Maxwell® RSC Blood DNA Kit, Promega, Madison, USA), following the manufacturer’s instructions. The

(23) SINE Insertion in LAMA3 in Dogs With Junctional Epidermolysis BullosaAnim GenetAugust 23, 2026Sarah Kiener, Ronnie Kaufmann, Ori Brenner, Vidhya Jagannathan, Tosso Leebincluded in the study was isolated from EDTA blood with the Maxwell RSC Whole Blood DNA Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland). One of the affected female dogs was whole‐genome sequenced as follows.

(24) Linking the Degree of Intrauterine Growth Restriction to Alterations in Metabolism, Energy Reserves, and Gut Health in Newborn PigletsJournal of Animal ScienceAugust 17, 2026Pau Salgado-López, Júlia Suppi, Katelyn N Gaffield, Mike D Tokach, Jaume Coma, Josep Gasa, David Solà-Oriolextracted with the Maxwell® RSC simplyRNA Tissue Kit (Promega Corporation, Madison, Wisconsin, USA) on a Maxwell® RSC instrument (Promega Corporation, Madison, Wisconsin, USA), following the manufacturer’s instructions. RNA quantity

(25) The telomeric DNA damage response as a therapeutic target in idiopathic pulmonary fibrosisEMBO Molecular MedicineAugust 12, 2026Francesca Rossiello, Giada Cicio, Sara Sepe, Alexandra Mancheno-Ferris, Valeria Cancila, Arianna Castellini, Federica Rey, Giorgio Bertolazzi, Alessia Oppezzo, Eugenia Marinelli, et al.then added, and samples were incubated at 56 °C for 10 min. RNA extraction was then performed using Maxwell® RSC Instrument (Promega), with Maxwell® RSC simplyRNA Tissue Kit (Promega, AS134), following the manufacturer’s instructions.

(26) Applicability of Nanopore-only whole-genome sequencing for Pseudomonas aeruginosa outbreak investigation in the ICU setting: a multicentric studyJournal of Clinical MicrobiologyAugust 12, 2026J. Dingemans, S. Vandersanden, P. Hilkens, J. Godelaine, K. Magerman, F. Crombé, D. De Geyter, A. Boel, P. Bruynseels, J. Frans, et al.suspensions of plate-grown bacterial cultures in DNA/RNA shield using the RSC Cultured Cells DNA kit on the Maxwell RSC instrument (Promega) according to the manufacturer’s instructions. DNA concentration was assessed using the Qubit fluorometer

(27) NUP153 immunoreactivity in neuroendocrine neoplasms supports the diagnosis of NET versus NEC and is modulated by post-translational modificationsJ NeuroendocrinolAugust 12, 2026Sven Mattern, Arslan Ali, Vanessa Hollfoth, Eyyub Bag, Katharina Kluthe, Esther Herpel, Frank Bergmann, Thomas Muley, Michael Meister, Judith Lehmann-Koch, et al.was extracted from macrodissected 5 μm paraffin sections using the Maxwell® RSC RNA FFPE Kit and the Maxwell® RSC Instrument (Promega, Madison, WI, USA) according to the manufacturer's instructions. For further information, see

(28) Patterned ELR‐Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface TopographyAdvanced Healthcare MaterialsAugust 10, 2026Jagoda Litowczenko, Yannick Richter, Martyna Michalska, Piotr Paczos, Karine Tadevosyan, Daniel Uribe, Jose Carlos Rodriguez‐Cabello, Ioannis Papakonstantinou, Angel RayaQuantitative Real‐Time Polymerase Chain Reaction (qRT‐PCR) Total RNA was extracted from iPSC‐ECs using Maxwell RSC simplyRNA Cells kits on a Maxwell RSC instrument (Promega). cDNA was synthesized from 1 µg RNA using Transcriptor First Strand cDNA kit (Roche). qPCR

(29) Environmental tuning of thyroid hormone signaling drives developmental plasticitySci AdvAugust 7, 2026Marcela Herrera, Saori Miura, Zoé Chamot, Mathieu Reynaud, Emma Gairin, Roger Huerlimann, Timothy Ravasi, Laurence Besseau, Yann Gibert, David Lecchini, et al.RNA was extracted from whole larvae using the Maxwell RSC simplyRNA Tissue Kit (Promega, USA) on the Maxwell RSC instrument, following the manufacturer’s instructions. RNA quantity and quality were assessed with an Invitrogen

(30) The Impact of Molecular Profile Changes and Other Histopathological Parameters on Endometrial Cancer RecurrenceCancers (Basel)July 30, 2026Robert Rottscholl, Johanna Winkelmann, Konstantin Fritz, Verena Gassenmaier, Isabell Goetting, Annette Staebler, Annika Simma, Sascha Hoffmann, Birgitt Schoenfisch, Stefan Kommoss, et al.from macrodissected 5 µm paraffin sections was performed using the Maxwell® RSC DNA FFPE Kit and the Maxwell® RSC Instrument (Promega, Madison, WI, USA) and followed by DNA quantification with the Qubit Fluorometer employing

(31) Biological, genomic, and biogeographic characterization of two lytic phages infecting Vibrio natriegensVirology JournalJuly 29, 2026Michiko Takahashiassembly, and phylogenetic analysis The genomic DNA of the isolated phages was extracted using the Maxwell RSC instrument (Promega, Madison, WI, USA) with the Maxwell RSC Genomic DNA Kit (Promega) according to the manufacturer’s

(32) Strong catchment-specific structuring of Swedish wastewater microbiomes in a paired two-timepoint metagenomic surveyFrontiers in MicrobiologyJuly 29, 2026Dhananjay Mukhedkar, Milan S. Stosic, Anna J. Székely, Ekaterina Avershina, Laila Sara Arroyo Mührinfluent wastewater using the Maxwell® RSC Enviro TNA Kit (Promega Corporation, Madison, WI, USA) on the Maxwell® RSC instrument (Promega Corporation, Madison, WI, USA), following the manufacturer’s instructions with the PureFood

(33) Genomic Alterations in Quadruple-Negative Breast Cancer TumorsInternational Journal of Molecular SciencesJuly 25, 2026Carolina Jaliffa, Uwe Rogel, Cornelia Leo, Gad Singerslices. Total nucleic acid (TNA) from tumor areas was isolated using the Maxwell® RSC RNA FFPE kit on the Maxwell® RSC instrument (Promega, Madison, WI, USA) according to the manufacturer’s instructions. DNA was quantified using the

(34) Natural products modulate social behavior and gut microbiota in a valproic acid-induced zebrafish model of autism spectrum disorderBiomolecules and BiomedicineJune 26, 2026Oana-Georgiana Oprea, Ioana-Miruna Balmus, Tudor Ilie, Gabriel Plavan, Mircea Nicusor Nicusor Nicoara, Lucian Gorgan, Anca Trifan, Bogdan Stoica, Bogdan-Ionel Tamba, Alin Ciobica, et al.intestinal samples using the Maxwell® RSC Fecal Microbiome DNA Kit (Promega, Madison, WI, USA) on a Maxwell RSC Instrument, following the manufacturer’s instructions. The concentration and purity of microbial DNA were assessed

(35) Microbiome histidine competition mediates dietary control of systemic imidazole propionatebioRxivJune 26, 2026Paola Nol Bernardino, Christian Jacoby, Isaac T. Younker, Joshua Stemczynski, Alexander S. Little, Michael W. Mullowney, Tess H. Brunner, Joyce Ghali, Matteo Fardin, Kelsey Rose, et al.extraction. Cell pellets were thawed and total RNA from biological replicates were extracted using the Maxwell RSC instrument (Promega). Extracted RNA was quantified using Qubit, and integrity was measured using TapeStation (Agilent

(36) Copy number variants in BRCA1 and BRCA2 genes in Polish patients with breast and ovarian cancerJournal of Cancer Research and Clinical OncologyJune 23, 2026Anna Doraczynska-Kowalik, Rafal Matkowski, Dagmara Michalowska, Agnieszka Chrusciel, Mariola Semeniuk, Dorota Blomka, Paulina Lawicka, Ewelina Czykalko, Mariola Abrahamowska, Aleksandra Pietron, et al.fresh whole blood using a Maxwell RSC Blood DNA Kit (Promega Corporation) and a Maxwell RSC isolator (AS4500, Promega Corporation) according to the manufacturer’s instructions. Following extraction, Quantus Fluorometer

(37) Circulating Cell-Free DNA Analysis for Diagnostic and Prognostic Assessment of Hepatocellular Carcinoma in CirrhosisInt J Mol SciJune 20, 2026Inés Aznar-Peralta, Amparo Roa-Colomo, Javier López Hidalgo, Cristobal Fresno, Valeria Denninghoff, María José SerranocfDNA cfDNA was extracted from plasma samples using the Maxwell® RSC cfDNA LV Plasma Kit with the Maxwell® RSC Instrument (Promega, Madison, WI, USA). The obtained cfDNA was immediately quantified using the Qubit dsDNA HS Assay Kit

(38) Telomere length and appendicular lean mass over six years in older adults with overweight or obesity and metabolic syndrome: a prospective cohort studyGeroScienceJune 20, 2026Héctor Vázquez-Lorente, María Fernández de la Puente, Julio Plaza-Diaz, Nancy Babio, Montse Fitó, Miguel Ángel Martínez-González, Sonia García-Calzón, Amelia Marti del Moral, Jordi Salas-Salvadófrom frozen buffy coat samples using the Maxwell RSC Blood DNA Kit (Promega, Madison, WI, USA) on the Maxwell RSC Instrument, following the manufacturer’s instructions. Relative leukocyte TL was determined at baseline using a

(39) Multiplex gene editing suppresses random integration of hepatitis B virus DNA in chronically infected liverMol Ther Nucleic AcidsJune 16, 2026Samuel Slattery, Wenwen Huo, Amena Arif, Jennifer Gordon, Ryo Takeuchiincubated at 80°C for 30 min prior to loading into the Maxwell RSC blood DNA cartridge and ran on the Maxwell RSC instrument. Genomic DNA was extracted from 293FT cells using a Maxwell RSC Cultured Cells DNA Kit (Promega) according

(40) Fibroblastic aspartoacylase suppresses TGFβ-mediated responses and cancer progressionNature CommunicationsJune 16, 2026Ianire Astobiza, Catalina Capó-Serra, Cristina Viera, Javier Rodríguez, Patricia Carnicero, Miguel Juliá, Ainara Martinez, Carmen Pérez-López, María Subijana, Carolina Ortiz-Sanz, et al.NucleoSpin® RNA isolation kit from Macherey-Nagel (ref: 740955.240 C) or automatically extracted using Maxwell RSC instrument (Promega) according to manufacturer´s instructions. Complementary DNA (cDNA) from 0.5 or 1 µg of the

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