Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(61) Extracellular Vesicle-Associated miR-222-3p and miR-186-5p as Potential Hypoxic Markers in Canine Osteosarcoma: A Preliminary In Vitro StudyAnimals (Basel)April 20, 2026Raffaella De Maria, Manuela Poncina, Sara Divari, Lorenza Parisi, Sonia Capellero, Luiza Cesar Conti, Eugenio Mazzone, Federica Fratini, Luca Aresu, Lorella ManiscalcoNo. AS1680, Madison, WI, USA) according to the manufacturer’s instructions, employing the automated Maxwell® RSC instrument (Promega, Madison, WI, USA) to ensure consistent yield and minimize manual handling. MiRNA concentration

(62) Dietary 1.3-1.6 yeast β-glucans enhance immune response and disease resilience in European seabass challenged with Tenacibaculum maritimumFrontiers in ImmunologyApril 20, 2026Miguel Cabano, Nadège Richard, Julie Schulthess, Lourenço Ramos-Pinto, Francisco Pinto-Cunha, Maria João Peixoto, Cláudia Aragão, Benjamin Costaswas extracted from posterior gut and skin tissues (n = 16, per diet × infection condition) using the Maxwell® RSC Instrument (Promega, USA) and the Maxwell® RSC simplyRNA Tissue Kit, following the manufacturer’s instructions.

(63) In cold blood: screening wild Alaskan moose (Alces alces gigas) for filarial nematode (Filarioidea: Onchocercidae) infections using a deep-amplicon sequencing approachParasitologyApril 20, 2026Matthew R. Kulpa, John A. Crouse, Daniel P. Thompson, Joe L. Luksovsky, John C. Blazier, John S. Gilleard, Guilherme G. Verocaithermomixer at 300 rpm for 30 minutes. Once complete, 200 μL of each sample was aliquoted and placed into a Maxwell® RSC Instrument (Promega Corporation, Madison, WI, USA) for automated DNA extraction using a Maxwell® RSC Tissue DNA Kit

(64) Antagonism by the type VI secretion system of Bacteroides fragilis is controlled by a TetR family regulator and released small moleculeProceedings of the National Academy of SciencesApril 14, 2026Leila Tuzlak, Téa E. Pappas, Michael J. Coyne, Madeline L. Sheahan, Victoria Burgo, Phoebe A. Rice, Laurie E. ComstockDNAse treatment and elution. Nucleic acid was recovered from broth grown bacterial cultures using the Maxwell RSC instrument (Promega Corporation, Madison, WI). RNA was quantified using QubitFlex (Life Technologies) and integrity

(65) Validation of a Duplex Digital PCR Assay for the Quantification of the NK603 Maize Event Across Three dPCR PlatformsFoodsApril 14, 2026Daniela Verginelli, Katia Spinella, Sara Ciuffa, Raffaele Carrano, Davide La Rocca, Elisa Pierboni, Monica Borghi, Silvana Farneti, Ugo Marchesistarting from 200 mg of CRMs was performed using the Maxwell® RSC PureFood GMO extraction method with the Maxwell® RSC Instrument (Promega Corporation, Madison, WI, USA), according to the manufacturer’s instructions, for the Bio-Rad

(66) Molecular Sex Determination in Caenophidian Snakes Using qPCR Amplification of Sex-Linked Genes: Validation and Interspecific ComparisonAnimals (Basel)April 11, 2026George Iulian Enacrachi, Anamaria Ioana Paştiu, Dana Liana Pustadorsal trunk region of the exuvium (Figure 2) to standardize sampling across individuals, using the Maxwell® RSC Instrument (Promega, Madison, WI, USA) and the Maxwell® RSC Genomic DNA Kit (Promega, USA), following the manufacturer’s

(67) Targeting noncanonical TGF-beta signaling: inhibition effects on the human keloid fibroblast transcriptomeItch (Phila)April 10, 2026Jordan Morningstar, Athira Sivadas, Martin Romeo, Silvia Vaena, Manuel Valdebran, Shawn G. Kwatra, Russell A. Norris, Tyler C. Beckextracted using the Promega Maxwell RSC automated instrument (Promega Corporation; catalog number: AS4500). Poly(A) enrichment was performed using the NEBNext Poly(A) mRNA Magnetic Isolation Module (New England Biolabs

(68) Deruxtecan-based antibody–drug-conjugates induce senescence in HER2-positive breast cancerScientific ReportsApril 9, 2026Elena Vezzoli, Riccardo Pinos, Silvia Galbiati, Desiree Zambroni, Chiara Dall’Ara, Alberta Locatelli, Emanuele Colombo, Barbara Galbardi, Lucia Viganò, Zeno Lavagnino, et al.°C. Maxwell® RSC Whole blood DNA kit (AS 1520) was used to extract DNA from cell pellets employing the Maxwell® RSC Instrument (Promega, Madison, WI, USA). DNA was eluted in 50 µL of Elution Buffer. The ddPCR mix was prepared in

(69) Genetic landscape of stage II melanoma identifies CBL as a new driver gene and prognostic biomarkerBritish Journal of CancerApril 9, 2026Elena Sophia Lindner, Jakob Admard, German Demidov, Sorin Armeanu-Ebinger, Tobias Sinnberg, Heike Niessner, Teresa Amaral, Claus Garbe, Andrea Forschner, Olga Kelemen, et al.isolated from 8 µm tumour and normal tissue paraffin sections using the Maxwell® RSC DNA FFPE Kit and the Maxwell® RSC Instrument (Promega, Madison, WI, USA) according to the manufacturer’s instructions. Library construction, hybrid

(70) Genome-Scale Phylogenetic Evidence Supports the Synonymy of Lasiodiplodia brasiliensis with Lasiodiplodia theobromaeJ Fungi (Basel)April 8, 2026Celynne Ocampo-Padilla, Yoshiki Takata, Shunsuke Nozawa, Yui Harada, Katsuhiko Ando, Kyoko Watanabeprocessed using the CTAB method combined with the Maxwell® RSC PureFood GMO and Authentication Kit on a Maxwell® RSC instrument (Promega Corporation, Fitchburg, WI, USA). DNA concentration and quality were assessed using a NanoDrop

(71) A Simple and Fast Protocol to Detect Nucleophosmin 1 (NPM1) Mutation and Fms-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3/ITD): Optimizing Laboratory RoutineMethods ProtocApril 3, 2026Alessandra Helena da Silva Hellwig, Gisele Menezes Ewald, Grazielle Motta Rodrigues, William Latosinski Matos, Juliana Bergmann, Viviane Horn de de Melo, Rodrigo Minuto Paiva, Dariane Castro Pereira, Eduardo Wandame GomezPCR-96-AB-C). 2.3. Equipment Maxwell® RSC Instrument (Promega Corporation, Madison, WI, USA; Cat. no.: AS4500);NanoDrop™ 2000 Spectrophotometers (Thermo Fisher Scientific, Waltham, MA, USA; Cat. no.: ND-2000);Benchtop

(72) CD9 regulates macrophage-mediated remodeling of adipose tissue in obesityJCI InsightMarch 23, 2026Julia Chini, Nicole DeMarco, Dana V. Mitchell, Sam J. McCright, Kaitlyn M. Shen, Divyansi Pandey, Rachel L. Clement, Jessica Miller, Rajan Jain, Deanne M. Taylor, et al.(Promega, AD1340). Briefly, tissue was homogenized in Thioglycerol Homogenization solution using a Maxwell RSC instrument (Promega). RNA was quantified using a NanoDrop 8000 spectrophotometer (Thermo Fisher Scientific) and

(73) Lipidomics of allantoic fluid collected by allantocentesis indicates a possible mechanism underlying partial litter loss in multifetal pregnancies of ewesScientific ReportsMarch 18, 2026Tamir Alon, Maya Ross, Jen Spirer, Priscila Dos Santos Silva, Alexander Rosov, Lila Lifshitz, Gitit Kra, Moran Gershoni, Sergey Malitsky, Maxim Itkin, et al.performed by Maxwell® RSC simplyRNA Kit (#AS1390, Promega, WI, USA) in a Maxwell® RSC Instrument (#AS4500, Promega). A total of 200 µL of each sample was transferred into a 1.5-mL microfuge tube along with

(74) Impact of Semi-Permanent Nail Polish on Forensic DNA Profiling and Phenotyping from FingernailsGenes (Basel)March 16, 2026Giulia Fazio, Sara Amurri, Arianna Giorgetti, Filomena Melchionda, Chiara Turchi, Susi Pelotti, Carla Binisamples was performed using the Maxwell® FSC DNA IQ™ Casework Kit (Promega, Madison, WI, USA) on a Maxwell® RSC Instrument, following the manufacturer’s protocol, “Automated Purification of DNA from Fingernail Clippings”. The

(75) Behavioral screening defines the molecular Parkinsonism-related subgroups in DrosophilaNature CommunicationsMarch 10, 2026Natalie Kaempf, Jorge S. Valadas, Pieter Robberechts, Nils Schoovaerts, Roman Praschberger, Antonio Ortega, Eliana Nachman, Lorenzo Ghezzi, Ayse Kilic, Dries Chabot, et al.Pink1KO-WS/y, for which we only used hemizygous males, at 1–5 days after eclosion. RNA was extracted using Maxwell RSC instrument and Maxwell RSC RNA kit (Promega) and transcribed using the SuperScript VILO cDNA Synthesis Kit (ThermoFisher Scientific

(76) Somatic and germline genomic variation in thymic carcinomasESMO OpenMarch 10, 2026F. Tettamanzi, C. De Carlo, C. Cappadona, D. Giuliano, V. Rimoldi, C. Piombo, L.G. Cecchi, S. Zanella, G. Marulli, E. Voulaz, et al.extracted from FFPE samples, using the Maxwell® RSC DNA FFPE Kit (Promega Corporation, Madison, WI) on a Maxwell® RSC instrument (Promega Corporation); gDNA extraction from blood samples was carried out using a Microlab STAR Liquid

(77) Clonal Dynamics of FLT3-ITD from Diagnosis to Relapse: Ultra-Sensitive Patient-Specific Monitoring by ddPCRInt J Mol SciMarch 8, 2026Alessandro Ferrando, Johanna Umurungi, Alice Costanza Danzero, Antonio Frolli, Rita Vacca, Arianna Savi, Giovanni Fornari, Valentina Gaidano, Alessandro Cignetti, Beatrice Sani, et al.from whole blood using the Maxwell RSC Blood DNA Kit (Promega, Madison, WI, USA) and processed on the Maxwell® RSC Instrument (Promega, Madison, WI, USA) according to the manufacturer’s instructions. DNA concentration and purity

(78) Binary vector origin predictably determines Agrobacterium -mediated transformation outcome across eukaryotic kingdomsbioRxivMarch 7, 2026Matthew J. Szarzanowicz, Michael Busche, Ziyu Dai, Nathan Lapp, Gina M. Geiselman, Jiayuan Jia, Lucas M. Waldburger, Yan Liang, Guoliang Yuan, Rylan Duong, et al.(BioSpec Products, Inc, Bartlesville, OK, USA). DNA was purified using the Maxwell® RSC plant DNA kit by the Maxwell® RSC instrument (Promega, Madison, WI, USA). Transgene insertion number quantification Transgene insertion number

(79) Identification of a miRNA signature for schizophrenia in plasma-derived extracellular vesiclesbioRxiv : the preprint server for biologyMarch 6, 2026Collier MEW, Chiappelli J, Marshall H, Sylvius N, Allcock N, Whittingham J, Kochunov P, Schwarcz R, Hong EL, Giorgini F.was isolated from the EV lysates using the Maxwell RSC miRNA from plasma and serum kit (Promega) on a Maxwell RSC instrument (Promega) according to the manufacturer’s instructions and eluted in 40 μl of nuclease free water. RT-qPCR

(80) Targeted BDNF upregulation via upstream open reading frame disruptionMolecular TherapyMarch 4, 2026Ning Feng, Thomas Goedert, Nenad Svrzikapa, Dongnan Yan, Hans J. Friedrichsen, Britt Hanson, Alicia Ljungdahl, Ruxandra Dafinca, Kevin Talbot, Stephan J. Sanders, et al.1. RT-qPCR To quantify firefly and Renilla luciferase transcripts, total RNA was first extracted using the Maxwell RSC Instrument and the Maxwell RSC simplyRNA Tissue Kit (both Promega). Reverse transcription was performed using the

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