Maxwell RSC Instrument from Promega

Product Specs
ItemMaxwell RSC Instrument
CompanyPromega
Price Supplier Page View Company Product Page
Catalog NumberAS4500
QuantityEA
Processing Time30 to 60 min (depending on sample type and method)
CapacityUp to 16
Dimensions(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV LampAvg. lifetime approximately 6,000 hrs
Molecular Weight~85kDa

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Promega

2800 Woods Hollow Rd

Madison, WI 53711

United States

Phone: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516

Email: custserv@promega.com
techserv@promega.com

Company Profile

Website: http://www.promega.com

(61) NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasmsNature CommunicationsNovember 26, 2025Ruth-Miriam Koerber, Calvin Krollmann, Kevin Cieslak, Elisabeth Tregel, Maria L. Saenz, Tim H. Brümmendorf, Steffen Koschmieder, Martin Griesshammer, Ines Gütgemann, Conny K. Baldauf, et al.(IBL). Quantitative RT–PCR RNA was extracted from cells with the Maxwell RSC simplyRNA Cells Kit (Promega) on a Maxwell RSC instrument and mRNA reverse transcribed with the RevertAid First Strand cDNA Synthesis Kit (Thermo Fisher Scientific).

(62) The host range of generalist and specialist phages in capsule-diverse Klebsiella hosts is driven by the evolvability of receptor-binding proteinsPLOS BiologyNovember 26, 2025Celia Ferriol-González, Pilar Domingo-Calap5-Kit (Zymo) for the passages and using Maxwell PureFood GMO and Authentication Kit (Promega) with Maxwell RSC Instrument (Promega) for single plaques. Sequencing libraries were prepared using the Illumina Nextera XT DNA kit

(63) Genomic landscape and molecular subtypes of primary central nervous system lymphomaBlood Cancer JournalNovember 26, 2025Shengjie Li, Danhui Li, Zuguang Xia, Jianing Wu, Jun Ren, Yingzhu Li, Jiazhen Cao, Ying Sun, Chengxun Li, Wenjun Cao, et al.DNA (gDNA) was extracted via the Maxwell RSC Blood DNA Kit (AS1400, Promega) on a Maxwell RSC system (AS4500, Promega) following the manufacturer’s instructions. For FFPE tissue, total gDNA was extracted via the

(64) Olutasidenib for mutated IDH1 acute myeloid leukemia: final five-year results from the phase 2 pivotal cohortJournal of Hematology & OncologyNovember 14, 2025Jorge Cortes, Antonio Curti, Pierre Fenaux, Brian A. Jonas, Jürgen Krauter, Pau Montesinos, Christian Récher, David C. Taussig, Eunice S. Wang, Justin Watts, et al.in PAXGene® tubes. Blood genomic DNA (gDNA) was isolated using the Maxwell® RSC Blood DNA Kit on the Maxwell® RSC Instrument (Promega, Madison, WI, USA), according to the manufacturer’s instructions. The yield of gDNA was assessed

(65) Identification of poultry commensal bacteria with the ability to inhibit the growth of Salmonella enterica serovar Typhimurium in co-cultureBMC MicrobiologyNovember 12, 2025Zhixuan Feng, Valérie Dagenais, Valérie Leclerc, Clara Pigozzo, Jennifer Ronholmincubation period. The suspension was then transferred into the DNA extraction cartridge and placed in the Maxwell® RSC instrument (Promega, USA). The DNA was extracted using the pre-programmed “Blood DNA extraction” program. The DNA

(66) Gut bacteria metabolize natural and synthetic steroid hormones via the reductive OsrABC pathwayCell Host & MicrobeNovember 12, 2025Christian Jacoby, Kaylie Scorza, Lia Ecker, Paola Nol Nol Bernardino, Alexander S. Little, Mary McMillin, Ramanujam Ramaswamy, Anitha Sundararajan, Ashley M. Sidebottom, Huaiying Lin, et al.processing. Cell pellets were thawed and total RNA from biological replicates were extracted using the Maxwell RSC instrument (Promega). Extracted RNA was quantified using Qubit, and integrity was measured using TapeStation (Agilent

(67) Germline Mutations in DNA Repair Genes in Patients with Pancreatic Neuroendocrine Neoplasms: Diagnostic and Therapeutic ImplicationsCurrent OncologyNovember 10, 2025Beata Jurecka-Lubieniecka, Małgorzata Ros-Mazurczyk, Aleksandra Sygula, Alexander J. Cortez, Marcela Krzempek, Anna B. Tuleja, Agnieszka Kotecka-Blicharz, Marta Cieslicka, Malgorzata Oczko-Wojciechowska, Daria Handkiewicz-JunakVacutainer® tubes. Genomic DNA was isolated from leukocytes using the Maxwell® RSC Blood DNA Kit on the Maxwell® RSC Instrument (Promega GmbH, Madison, WI, USA). DNA concentration and quality were assessed using the Qubit® 2.0 fluorometer

(68) Altered expression of autophagy-related molecules and β-catenin in different subtypes of thyroid cancer: co-localization in intranuclear cytoplasmic inclusionsEndocrine JournalNovember 4, 2025Yerkezhan Sailaubekova, Katsuya Matsuda, Yuko Akazawa, Hirokazu Kurohama, Yuki Matsuoka, Keiji Suzuki, Adiya Kerimbayeva, Hisayoshi Kondo, Van Phu Thang Nguyen, Thi Ngoc Anh Nguyen, et al.56°C. DNA extraction was performed using a Maxwell RSC DNA FFPE kit (Promega, Madison, WI, USA) and Maxwell RSC instrument (Promega), according to the manufacturer’s protocols. The concentration of double-strand DNA was quantified

(69) Oxford Nanopore Technologies [ONT] Sequencing: Clinical Validation in Genetically Heterogeneous DisordersGenes (Basel)November 3, 2025Mario Urtis, Chiara Paganini, Viviana Vilardo, Antonio Tescari, Samantha Minetto, Claudia Cavaliere, Andrea Pilotto, Carmela Giorgianni, Alessia Cattaneo, Marilena Tagliani, et al.Supplementary Table S1. 2.4. DNA Isolation DNA previously extracted from peripheral blood samples by Maxwell RSC Instrument (Promega, Madison, WI, USA) using Maxwell CSC Blood DNA Kit (Promega) according to the manufacturer’s

(70) Collective homeostasis of condensation-prone proteins via their mRNAsNatureNovember 1, 2025Faraway R, Costello Heaven N, Digby H, Kuret Hodnik K, Rebselj J, Wilkins OG, Chakrabarti AM, Iosub IA, Vadnjal N, Dore R, et al.extractions were performed from cell pellets using the Maxwell RSC simplyRNA kit (Promega) using a Maxwell RSC Instrument (Promega). 3′ End sequencing For each sample, 250 ng µl−1 of RNA was fragmented in 10 mM Tris-HCl

(71) TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast CancerAdvanced ScienceNovember 1, 2025Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, et al.silenced cells using the Maxwell RSC miRNA Tissue kit (AS1460, Promega) with the Maxwell RSC Instrument (AS4500, Promega). cDNA preparation was performed using the i‐Script reverse transcription Supermix Real Time

(72) Preclinical biodistribution and toxicology assessment of an AAV5-based subretinal modifier gene therapy for retinitis pigmentosaFrontiers in MedicineOctober 29, 2025Arun Upadhyay, Selina Drag, Pushpendra Singh, Kalpana Rajanala, Rasappa Arumughamtissues were procured at Charles River Laboratories. DNA was isolated from study tissues using the Maxwell® RSC Instrument and Maxwell® RSC Blood DNA Kit (Promega, AS1400) and quantified by spectrophotometer (SpectraMax). Samples

(73) Loss of histone macroH2A1.1 causes kidney abnormalities secondary to a change in nutrient metabolizationSci AdvOctober 24, 2025René Winkler, Gemma Comas-Armangué, David Corujo, Adrián Sanz-Moreno, Julia Calzada-Wack, Shubhra Ashish Bhattacharya, Birgit Rathkolb, Nathalia Romanelli Vicente Dragano, Colina X. Qiao, Valentina Chiodi, et al.RNA was isolated from at least 20 mg of homogenized tissue using an automatic purification platform (Maxwell RSC Instrument, Promega, Madison, WI, USA) and the corresponding Maxwell RSC simplyRNA Tissue Kit (Promega) according

(74) Comparative Analysis of Concentration and Quantification Methods for Antibiotic Resistance Genes and Their Phage-Mediated Dissemination in Treated Wastewater and BiosolidsPathogensOctober 18, 2025Irene Falcó, Ana Allende, Francesca Cutrupi, Rosa Aznar, Gloria Sánchez, Pilar Truchadousing the Maxwell RSC Pure Food GMO and Authentication Kit (Promega, Southampton, UK) along with the Maxwell® RSC Instrument (Promega, UK). Briefly, 300 μL of the concentrated water samples or resuspended biosolids were added

(75) Malignant Potential of Thyroid Follicular Nodular Disease With Solid/Trabecular Components: A Case ReportPathology InternationalOctober 15, 2025Mayu Ueda, Katsuya Matsuda, Yusuke Mori, Hirokazu Kurohama, Hiroyuki Mishima, Koh‐Ichiro Yoshiura, Norisato Mitsutake, Hisakazu Shindo, Shinya Sato, Hiroyuki Yamashita, et al.Out‐N, In‐N, and the skin tumor using the Maxwell RSC DNA FFPE Kit (Promega, Madison, WI, USA) with the Maxwell RSC Instrument (Promega). Libraries were prepared from 50 ng of DNA using NEBNext FFPE DNA Repair Mix (Biolabs, Tokyo,

(76) RNA-seq Splicing Profile of the CDH1 Gene and Its Impact on the Clinical Pathogenicity Classification of CDH1 Variants: A Description of Alternative and Pathogenic Splicing PatternsCancers (Basel)October 14, 2025Molka Sebai, Roseline Tang, Yahia Adnani, Alice Fievet, Odile Cabaret, Marie-Aude Robert de Rancher, Nathalie Auger, Yasmina Elaribi, Houweyda Jilani, Jean-Marc Limacher, et al.extraction using Maxwell RSC SimplyRNA Blood kit (AS1380) (Promega Corporation, Madison, WI, USA) on Promega Maxwell RSC Instrument for LCLs and Maxwell RSC RNA FFPE kit (AS1440) for FFPE blocks. RNA yield and RNA quality were checked

(77) Impact of Light-Activated Nanocomposite with Erythrosine B on agr Quorum Sensing System in Staphylococcus aureusAntibiotics (Basel)October 11, 2025Larysa Bugyna, Ľubomír Švantner, Katarína Bilská, Marek Pribus, Helena BujdákováMD-01N-110/220, Major Science, Saratoga, CA, USA) and centrifuged (5 min, 10,413× g). For RNA isolation, a Maxwell RSC instrument (Promega, Madison, WI, USA) was used. A total of 600 µL of each sample, 10 µL of DNase (the Maxwell RSC miRNA Tissue Kit

(78) The Derkay Scale as a Predictor of Voice Dysfunction in Recurrent Respiratory Papillomatosis: Correlations Between Acoustic and Patient-Reported OutcomesJ Clin MedOctober 8, 2025Beata Miaśkiewicz, Elżbieta Gos, Aleksandra Panasiewicz, Paulina Krasnodębska, Dominika Oziębło, Monika Ołdak, Agata Szkiełkowskawas isolated from the collected tissue using the commercial Maxwell FSC DNA IQ Casework Kit and the Maxwell RSC instrument following the manufacturer’s protocol (Promega, Walldorf, Germany). Subsequently, virus genotyping was

(79) ALOXE3 missense variant in a Chihuahua with autosomal recessive ichthyosisAnim GenetOctober 7, 2025Carina Vinberg, Stefan J. Rietmann, Sara Soto, Vidhya Jagannathan, Susanne Åhman, Tosso Leebwhole genome sequencing Genomic DNA was extracted from EDTA blood samples using a Maxwell RSC Whole Blood Kit on a Maxwell RSC instrument (Promega, Dübendorf, Switzerland). For whole genome sequencing of the affected dog, a PCR‐free library

(80) RNA-seq dataset of land snails collected in AustraliaData BriefOctober 4, 2025Berenice Talamantes-Becerra, Wei-Shan Chang, Michelle Michie, Mike Hodda, Mariana Hopper, Valerie Caronprotocol of Maxwell ® RSC simplyRNA Tissue Kit (Promega A1340) and the Maxwell ® RSC Instrument (Cat. AS4500). The modification done to the protocol was the inclusion of 400 µL of lysis buffer to each cooled homogenate,

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