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Maxwell® RSC 48 Instrument
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Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument from Promega
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Citations:
(175)
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Maxwell® RSC 48 Instrument
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Description
The Maxwell RSC 48 Instrument is a platform for automated purification of nucleic acid from a range of sample types. Purification methods use sample lysis and binding to paramagnetic particles as the primary separation principle.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell® RSC 48 Instrument
Company
Promega
Price
Supplier Page
Catalog Number
AS8500
Quantity
EA
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (175)
(1)
Highly focused human CD8+ T-cell response in the lower airways during acute influenza infection
J Immunol
May 19, 2026
Adam Saidu, Jeremy Chase Crawford, Sarah Walden, Jia-Hua Qu, Heather M Machkovech, Fangjie Han, Resha Sisti, E Kaitlynn Allen, Daniel Reynolds, Nicholas Borcherding,
et al.
universal transport media or BALF using the Viral Total
Nucleic Acid Purification
kit (
Promega
) on a
Maxwell RSC 48 instrument
and eluted in 50 µL of nuclease-free water according to the manufacturer’s instructions. For
RT-PCR
,
(2)
Natural senolytic activity of Rhodiola rosea extract alleviates age-associated phenotypes via paraptosis
iScience
May 15, 2026
Ryo Furuuchi, Yohko Yoshida, Goro Katsuumi, Takaaki Furihata, Yusuke Joki, Chieh-Lun Hsiao, Masayoshi Suda, Hana Saito, Tamano Kumazaki, Hidefumi Makabe,
et al.
was extracted from tissue and cell samples using either QIAzol Lysis Reagent (
QIAGEN
,
79306
) or the
Maxwell RSC 48 Instrument
(
Promega
) in combination with the
Maxwell RSC simplyRNA Tissue Kit
(
Promega
,
AS1340
), according to the
(3)
Adapting Clinical Chemistry Plasma as a Source for Liquid Biopsies
eLife
May 1, 2026
Spencer C Ding, Jingru Yu, Tiepeng Liao, Lauren S Ahmann, Yvette Y Yao, Chandler Ho, Linlin Wang, Benjamin A Pinsky, Wei Gu
described (Gu et al., 2021). DNA extraction cfDNA was extracted from 0.5 to 1 mL of plasma using the
Maxwell RSC 48 instrument
(
Promega
) with the
Maxwell RSC ccfDNA Plasma Kit
(
AS1480
), following the manufacturer’s instructions.
(4)
Rapid Preparation of Electrocompetent Listeria monocytogenes and Enhancement of Transformation Efficiency with cAMP Supplementation☆
Journal of Food Protection
May 1, 2026
A.V. Gutiérrez, N. Som, E. Smith, M. Diaz, M. Matthews, R.A. Kingsley, M. Gilmour
for short-read
sequencing
was extracted from 800 µL of overnight culture in BHI using the automated
Maxwell® RSC 48 instrument
and the Maxwell® RSC
Cultured Cells
DNA (
Promega
; Madison, WI, USA) kit following the manufacturer’s
(5)
Adapting clinical chemistry plasma as a source for liquid biopsies
Elife
May 1, 2026
Spencer C Ding, Jingru Yu, Tiepeng Liao, Lauren Ahmann, Yvette Yao, Chandler Ho, Linlin Wang, Benjamin A Pinsky, Wei Gu
described (Gu et al., 2021). DNA extraction cfDNA was extracted from 0.5 to 1 mL of plasma using the
Maxwell RSC 48 instrument
(
Promega
) with the
Maxwell RSC ccfDNA Plasma Kit
(
AS1480
), following the manufacturer’s instructions.
(6)
Intranasal Immunization with Live-Attenuated RSV-Vectored SARS-CoV-2 Vaccines Elicits Antigen-Specific Systemic and Mucosal Immunity and Protects Against Viral Challenge and Natural Infection
Vaccines (Basel)
April 29, 2026
Davide Botta, Michael D. Schultz, Aaron Silva-Sanchez, Davies Kalange, Jobaida Akther, Fen Zhou, Jennifer L. Tipper, Guang Yang, Levi T. Schaefers, Courtney A. Barkley,
et al.
(
Promega
, Madison, WI, USA), vortexed, and incubated at 56 °C for 10 min. RNA was extracted using the
Maxwell® RSC 48 Instrument
(
Promega
) according to the manufacturer’s instructions. Quantitative
RT-PCR
was performed on a QuantStudioTM
(7)
QTL mapping of vernalization-insensitive and photoperiod-independent early flowering in yellow lupin (Lupinus luteus L.)
Frontiers in Plant Science
April 23, 2026
Ishani Dogra, Allen Eldho-Paul, Anna Surma, Sandra Rychel-Bielska, Wojciech Bielski, Bartosz Kozak, Michał Książkiewicz
2 mL tubes (Eppendorf, Hamburg, Germany). DNA isolation was performed with the
aid
of an automated
Maxwell® RSC 48 Instrument
station (
Promega
, Mannheim, Germany), using a
Maxwell® RSC PureFood GMO and Authentication Kit
(
Promega
)
(8)
Molecular Characterization of Syndromic Hearing Loss in North African Moroccan Families
Biomolecules
April 22, 2026
Khawla El Fizazi, Amama Ghaffar, Laila Bouguenouch, Irum Badshah Saleem, Karim Ouldim, Zubair M. Ahmed, Mohammed Ridal, Saima Riazuddin
Bioinformatic Analysis
Blood samples were obtained from all participants. Genomic DNA was extracted using a
Maxwell RSC 48 Instrument
(
Promega Corporation
, Madison, WI, USA) with a
Maxwell RSC Blood DNA Kit
, and DNA concentration (ng/μL)
(9)
Mapping Genomic Heterogeneity in Pediatric and Adolescent–Young Adult Sarcomas: Insights from the Italian SAR-GEN2016 and SAR-GEN_ITA Prospective Multicenter Trials
Cancer Res Commun
April 1, 2026
Elisa Tirtei, Valeria Difilippo, Federico Divincenzo, Sebastian Dorin Asaftei, Nicola Ratto, Raimondo Piana, Pietro Pellegrino, Alessandra Linari, Mauro Papotti, Katia Mareschi,
et al.
2-μm-thick FFPE sections (8–10 sections per sample) using
Maxwell RSC DNA FFPE Kit
(
Promega Corporation
) on
Maxwell RSC 48 Instrument
(
Promega Corporation
) following the manufacturer’s protocol. DNA from peripheral blood samples was used
(10)
Mapping genomic heterogeneity in paediatric and adolescent-young adult sarcomas: insights from the Italian SAR-GEN2016 and SAR-GEN_ITA prospective multicenter trials
Cancer Research Communications
April 1, 2026
Elisa Tirtei, Valeria Difilippo, Federico Divincenzo, Sebastian Dorin. Asaftei, Nicola Ratto, Raimondo Piana, Pietro Pellegrino, Alessandra Linari, Mauro Papotti, Katia Mareschi,
et al.
2-μm-thick FFPE sections (8–10 sections per sample) using
Maxwell RSC DNA FFPE Kit
(
Promega Corporation
) on
Maxwell RSC 48 Instrument
(
Promega Corporation
) following the manufacturer’s protocol. DNA from peripheral blood samples was used
(11)
Intranasal immunization with live-attenuated RSV-vectored SARS-CoV-2 vaccines elicits antigen-specific systemic and mucosal immunity and protects against viral challenge and natural infection
bioRxiv
March 31, 2026
Davide Botta, Michael D. Schultz, Aaron Silva-Sanchez, Davies Kalange, Jobaida Akther, Fen Zhou, Jennifer L. Tipper, Guang Yang, Levi T. Schaefers, Courtney A. Barkley,
et al.
Maxwell® RSC Viral Total Nucleic Acid Purification Kit
(
Promega
), vortexed, and incubated at 56 °C for 10 min. RNA was extracted using the
Maxwell® RSC 48 Instrument
(
Promega
) according to manufacturer’s instructions. Quantitative
RT-PCR
was performed on a QuantStudio™
(12)
Evaluating long-term stool preservation methods for maximizing the recovery of viable human fecal microbiota
Gut Microbes Reports
March 30, 2026
Youzheng Teo, Anton Lavrinienko, Diana Albertos Torres, Paul Tetteh Asare, Antonia Ruder, Maria Gloria Dominguez-Bello, Adrian Egli, Nicholas A. Bokulich, Pascale Vonaesch
RSC PureFood GMO and Authentication Kit (
Promega
,
AS1600
) and a
Maxwell RSC 48 instrument
(
Promega
,
AS8500
). The bacterial suspensions were thawed, and 200 µL of the suspension was transferred into a PowerBead
(13)
SMARCA4-deficient carcinoma of the head and neck region: report of 8 new sinonasal and non-sinonasal cases and literature review
Virchows Archiv
March 9, 2026
Mihaela Farkas, Abbas Agaimy, Marián Švajdler, Lukáš Hauer, Petr Martínek, Tomáš Vaněček, Kristýna Pivovarčíková, Barbora Prchlíková, Roderick H. W. Simpson, Klaudia Gočárová,
et al.
to 3 FFPE sections (10 µm thick) were used and DNA was extracted using
Maxwell RSC DNA FFPE Kit
on
Maxwell RSC 48 Instrument
(
Promega
, Madison, WI, USA). DNA was quantified using the Qubit Broad Range DNA
Assay
(Thermo Fisher
(14)
Next‐Generation Short‐Read Sequencing Reveals Impacts on Major Histocompatibility Complex Diversity Resulting From Differences in Captive Rhesus Macaque ( Macaca Mulatta ) Colony Expansion Strategies
American Journal of Primatology
February 27, 2026
Sreetharan Kanthaswamy, Roger W. Wiseman, Miranda R. Stauss, Max C. Ertl, Divy K. Patel, David G. Smith, Melween I. Martínez, Elizabeth Maldonado, Carlos A. Sariol
isolated from barcoded blood tubes using Maxwell® Buffy Coat DNA Kits with a Maxprep® Liquid Handler and
Maxwell® RSC 48 instrument
(
Promega
, Madison, WI). Barcoding and robotic liquid handling helped prevent sample mix-ups. Purified
(15)
Adapting Clinical Chemistry Plasma as a Source for Liquid Biopsies
medRxiv
February 27, 2026
Spencer C. Ding, Jingru Yu, Tiepeng Liao, Lauren S. Ahmann, Yvette Y. Yao, Chandler Ho, Linlin Wang, Benjamin A. Pinsky, Wei Gu
described(26). DNA extraction Cell-free DNA (cfDNA) was extracted from 0.5 to 1 mL of plasma using the
Maxwell RSC 48 instrument
(
Promega
) with the
Maxwell RSC ccfDNA Plasma Kit
(
AS1480
), following the manufacturer’s instructions.
(16)
Immunopeptidomics of cutaneous leishmaniasis patients reveals the natural antigenic landscape
Frontiers in Immunology
February 20, 2026
Nicky de Vrij, Elise Pepermans, Louise Laurijssen, Thao-Thy Pham, Lauren Thijs, Kurt Boonen, Kadrie Ramadan, Ilse Maes, Yetemwork Aleka, Mekibib Kassa,
et al.
the
mass spectrometry
-based immunopeptidomics
assay
(Cohort 1 study samples) (Figure 1), using the
Maxwell® RSC 48 instrument
(
Promega
, Wisconsin, U.S.A.) with the
Maxwell® RSC Whole Blood DNA kit
(
Promega
, Wisconsin, U.S.A.)
(17)
Pitfalls in body fluid identification – age independent DNA methylation markers for vaginal secretions and menstrual blood in sexual assaults
International Journal of Legal Medicine
February 19, 2026
Helen Konrad, Leandra Jürgens, Paula Hiekel, Sophie Fertyk, Daniela Wübbe, Benno Hartung, Micaela Poetsch
site. DNA extraction was performed using the DNA IQ Casework Pro Kit and
Casework Extraction Kit
in the
Maxwell® RSC 48 instrument
(
Promega
, Walldorf, Germany). Subsequently, DNA was quantified using the
PowerQuant™ System
(
Promega
)
(18)
Development of a non-invasive diagnostic method for pathogenic RNA viruses using sebum wiped from the cat’s body surface
Scientific Reports
February 18, 2026
Yuri V Fukushima, Namiko Saito, Hirohisa Mekata, Akatsuki Saito
RNA from cat BSLs was processed using the
Maxwell® RSC 48 Instrument
(
Promega
, Madison, WI, USA; Cat#
AS8500
) in combination with the
Maxwell® RSC miRNA Plasma and Serum Kit
(
Promega
; Cat#
AS1680
), according to
(19)
Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect
J Exp Med
February 2, 2026
Kyle Rhodehouse, Carolin Zitzmann, Meghana Ravi, Ciara Armstrong, Milica Moskovljevic, Hannah P. Moore, Courtney Schill, Emily J. Fray, Mithra R. Kumar, Toni Penney,
et al.
(Del Prete et al., 2016). Animal genotyping Genomic DNA was isolated from whole blood samples with a
Maxwell RSC 48 instrument
using a
Maxwell RSC Buffy Coat DNA kit
according to the manufacturer’s protocol (
Promega
). Amplicons
(20)
The COMFORTage project: study protocol for the integration of multiple sources towards personalised preventions at Ace Alzheimer Center Barcelona
Frontiers in Digital Health
January 26, 2026
Sergi Valero, Andrea Miguel, Josep Blazquez-Folch, Berta Calm, Montserrat Alegret, Ariadna Solivar, George Manias, Athos Antoniades, Nelina Angelova, Despina Psimaris,
et al.
research purposes (42). 2.4.6
Genotyping
Genomic DNA is extracted from buffy coat samples using the
Maxwell RSC 48 instrument
(
Promega
) with the
AS1540
DNA extraction kit, ensuring high-quality samples for genetic analysis, and
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Maxwell® RSC 48 Instrument from Promega
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