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Maxwell® RSC 48 Instrument
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Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument from Promega
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Citations:
(183)
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Maxwell® RSC 48 Instrument
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Description
The Maxwell RSC 48 Instrument is a platform for automated purification of nucleic acid from a range of sample types. Purification methods use sample lysis and binding to paramagnetic particles as the primary separation principle.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell® RSC 48 Instrument
Company
Promega
Price
Supplier Page
Catalog Number
AS8500
Quantity
EA
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (183)
(41)
Mucosal delivery of influenza antigens using a replication deficient adenovirus supports broadly reactive antibody responses and heterologous viral immunity in the respiratory tract of animals
bioRxiv
October 17, 2025
Michael D. Schultz, Davide Botta, Aaron Silva-Sanchez, Isabella R. Cheatwood, Davies Kalange, Sarah M. Terapane, Aaron C. K. Lucander, Fen Zhou, Jobaida Akther, Guang Yang,
et al.
vortexed and incubated at 56°C for 10 min for
viral inactivation
prior to RNA extraction using the
Maxwell® RSC 48 Instrument
(
Promega
, Madison, WI). Quantification of influenza A viral N RNA was performed via
qRT-PCR
on a QuantStudio™
(42)
Chromatin remodeling restrains oncogenic functions in prostate cancer
Nature communications
October 16, 2025
Rosti V, Lembo G, Petrini C, Gorini F, Quadri R, Cordiglieri C, Mutarelli M, Salviato E, Casari E, Di Patrizio Soldateschi E,
et al
.
stored frozen at −80 °C for total RNA automated
purification
using
Maxwell® RSC 48 Instrument
(
Promega
,
AS8500
). Total RNA was quantified by Qubit 4 fluorometer with
Qubit RNA HS Assay Kit
(
Invitrogen
,
Q32852
) and
(43)
Analysis of myeloid neoplasms with isolated trisomy 19 reveals a novel MDS subgroup characterized by the presence of ring sideroblasts, fibrosis and SRSF2 and/or ASXL1 mutations
J Hematop
October 9, 2025
Konnie M. Hebeda, Ludmila Boudová, Maarten F. Corsten, Nikola Ptáková, Torsten Haferlach, Aniek O. de Graaf, Jaroslav Cermak, Tomas Vanecek, Joop H. Jansen, Marian J. P. L. Stevens-Kroef,
et al.
paraffin embedded BM
biopsies
was extracted from tissue slides using an FFPE DNA kit (automated on
Maxwell RSC 48 Instrument
,
Promega
, Madison, Wisconsin, USA) or a DNA/RNA Kit (Qiagen). The DNA was purified using AMPure XP Beads
(44)
Intestinal Myo-Inositol Metabolism and Metabolic Effects of myo-Inositol Utilizing Anaerostipes rhamnosivorans in Mice
International Journal of Molecular Sciences
September 24, 2025
Aldo Grefhorst, Antonella S. Kleemann, Stefan Havik, Antonio Dario Troise, Sabrina De Pascale, Andrea Scaloni, Max Nieuwdorp, Thi Phuong Nam Bui
tubes to ensure full recovery. The supernatant was mixed with nuclease-free water and placed into the
Maxwell RSC 48 instrument
(
Promega
, Madison, WI, USA) to extract DNA. The DNA concentration was measured with the
Qubit dsDNA BR assay kit
(45)
Comparing DNA Isolation and Preparation Protocols for Dried Blood Spots in the Context of Genomic Newborn Screening
International Journal of Neonatal Screening
September 3, 2025
Annelotte J. Duintjer, Sandra Imholz, Ingrid Pico-Knijnenburg, Adinda Heuperman, Hennie Hodemaekers, Eva S. Deutekom, Els Voorhoeve, Martijn E. T. Dollé, Mirjam van der Burg
was eluted in 35 µL stabilizing buffer. In protocol 8 (‘Maxwell’), DNA isolation was performed on the
Maxwell® RSC 48 instrument
using the
Maxwell® RSC FFPE Plus DNA Kit
(
Promega
, Madison, WI, USA) with its corresponding protocol
(46)
The Influence of Maternal Inflammatory Status on Fetal Telomere Length at Birth
Biomedicines
August 14, 2025
Mircea Diaconu, Flavius Olaru, Ahmed Abu-Awwad, Simona-Alina Abu-Awwad, Tiberiu Dragomir, Geanina Sacarin, Nicolae Ciprian Pilut, Bogdan Sorop, Melisa Bicu, Razvan Nitu
leucocytes were isolated for DNA extraction using the
Maxwell® RSC Buffy Coat DNA Kit
and processed on a
Maxwell® RSC 48 Instrument
(
Promega Corporation
, Madison, WI, USA). 2.4. Inflammatory Marker Analysis (
ELISA
) High-
sensitivity
(47)
GLI1/2-altered mesenchymal tumors: a study of 8 cases expanding the clinicopathological and molecular spectrum including an upstream PTCH1-inactivating mutation
Virchows Archiv
August 14, 2025
L. S. Hiemcke-Jiwa, R. van Ewijk, M. M. van Noesel, B. B. J. Tops, S. A. Koppes, S. F. K. Lubeek, G. N. Jonges, A. J. Witkamp, A. von Deimling, A. H. G. Cleven,
et al.
analyses Targeted mRNA sequencing According to standard protocols, RNA was isolated from FFPE with the
Maxwell RSC 48 Instrument
(
Promega
, Madison, Wisconsin, USA) using the RNA FFPE kit (promega), and cDNA libraries were generated
(48)
Genetic and antigenic characterization of classical and recombinant waterfowl parvoviruses circulating in Taiwan
Poult Sci
August 7, 2025
Yu-Chen Hsu, Kuang-Po Li, Poa-Chun Chang, Jui-Hung Shien, Wei-Li Hsu, Hua Yen, Jung-Pin Hsu, Tai-Ting Chen, Shan-Chia Ou
nucleic acids from collected organ samples were extracted using a Maxwell® RSC Viral TNA kit with a
Maxwell® RSC 48 Instrument
(
Promega
, Madison, USA), according to the manufacturer’s instructions. Extracted nucleic acid was used
(49)
Oregano-based feed additive reduces Salmonella enterica serovar Enteritidis colonization in young broilers
Poultry Science
August 1, 2025
Christina L. Swaggerty, M. Dolores Cabrera, Santiago Sasia, Gabriel Cabrera, Kenneth J. Genovese, J. Allen Byrd, Michael H. Kogut, Rafael A. Cabrera
then loaded into the Maxwell cartridge for RNA isolation. All RNA extractions were carried out on the
Maxwell® RSC 48 instrument
(
Promega
Corp.). Upon completion, the purified RNA samples were stored at −80°C. Quantitative
real-time RT-PCR
(50)
Bioluminescence-based assays for quantifying endogenous protein interactions in live cells
Journal of Biological Chemistry
August 1, 2025
Andrew L. Niles, Michael R.C. Dibble, Thomas Machleidt, Kelli Martino, Matthew R. Swiatnicki, Elizabeth H. Vu, Marie K. Schwinn
clones
was isolated from 5 × 104 to 5 × 105 cells using the Maxwell RSC Culture Cells DNA Kit and the
Maxwell RSC 48 Instrument
(
Promega
) according to the manufacturer’s protocol. DNA was quantitated on the
NanoDrop 8000 Spectrophotometer
(51)
Evaluation of the Global White Lupin Collection Reveals Significant Associations Between Homologous FLOWERING LOCUS T Indels and Flowering Time, Providing Validated Markers for Tracking Spring Ecotypes Within a Large Gene Pool
Int J Mol Sci
July 17, 2025
Wojciech Bielski, Anna Surma, Michał Książkiewicz, Sandra Rychel-Bielska
Qiagen, Hilden, Germany) using
TissueLyser II
(
Qiagen
) at 30 rpm for 30 s. The automated isolation system
Maxwell® RSC 48 Instrument
(
Promega
, Mannheim, Germany) and the
Maxwell® RSC PureFood GMO and Authentication Kit
(
Promega
) [103]
(52)
KDM6A expression loss is frequent in low grade non-invasive urothelial carcinomas of the urinary bladder
Pathologica
June 30, 2025
Florian Viehweger, Natalia Gorbokon, Seyma Büyücek, Henning Plage, Sebastian Hofbauer, Kira Furlano, Sarah Weinberger, Bernhard Ralla, Annika Fendler, Nadine Biernath,
et al.
FFPE specimens using the
Maxwell® RSC DNA FFPE Kit
(
Promega Corporation
, Madison, WI, USA) and the
Maxwell RSC 48 Instrument
according to the manufacturer’s instructions. Targeted gene
sequencing
was performed on a MiniSeq (Illumina,
(53)
KDM6A expression loss is frequent in low grade non-invasive urothelial carcinomas of the urinary bladder
Pathologica
June 30, 2025
Florian Viehweger, Natalia Gorbokon, Seyma Büyücek, Henning Plage, Sebastian Hofbauer, Kira Furlano, Sarah Weinberger, Bernhard Ralla, Annika Fendler, Nadine Biernath,
et al.
FFPE specimens using the
Maxwell® RSC DNA FFPE Kit
(
Promega Corporation
, Madison, WI, USA) and the
Maxwell RSC 48 Instrument
according to the manufacturer’s instructions. Targeted gene
sequencing
was performed on a MiniSeq (Illumina,
(54)
Serum RNA Profile Reflects Fluid Status and Atrophic Retinal Changes in Neovascular Age-Related Macular Degeneration
Int J Mol Sci
May 19, 2025
Hanna Heloterä, Joanna Kostanek, Mikko Liukkonen, Leea Siintamo, Suvi Linna-Kuosmanen, Cezary Watala, Janusz Blasiak, Kai Kaarniranta
Life Science (HiLIFE) and Biocenter Finland. Total RNA was extracted (serum volume 1 mL) using the
Maxwell® RSC 48 Instrument
(Madison, WI, USA) and
Maxwell RSC miRNA Plasma and Serum Kit
(
Promega
, Madison, WI, USA) following
(55)
Pathological Characterization of African Swine Fever Viruses With Genetic Deletions Detected in South Korea
Transbound Emerg Dis
May 6, 2025
Seong-Keun Hong, Ki-Hyun Cho, Jung-Hoon Kwon, Da-Won Kim, Jongho Kim, Da-Young Kim, Hae-Eun Kang, Jong-Soo Lee, Yeon-Hee Kim
Extraction and
Real-Time PCR
Analysis Automatic DNA extraction was carried out in accordance with the
Maxwell RSC 48 instrument
using Maxwell RSC whole blood DNA and
Maxwell RSC viral total nucleic acid purification kit
(
Promega
,
(56)
Molecular dissection of the genetic architecture of phenology underlying Lupinus hispanicus early flowering and adaptation to winter- or spring sowing
Sci Rep
May 2, 2025
Wojciech Bielski, Anna Surma, Jolanta Belter, Bartosz Kozak, Michał Książkiewicz, Sandra Rychel-Bielska
homogenizer (
Qiagen
, Hilden, Germany) for 45 s at 30 rpm. DNA isolation was performed in automated station
Maxwell® RSC 48 Instrument
(
Promega
, Mannheim, Germany) using
Maxwell® RSC PureFood GMO and Authentication Kit
(
Promega
) according
(57)
Population structure and gene flux of Listeria monocytogenes ST121 reveal prophages as a candidate driver of adaptation and persistence in food production environments
Microb Genom
April 17, 2025
Ana Victoria Gutiérrez, Michaela Matthews, Maria Diaz, Thanh Le Viet, Leonardo de Oliveira Martins, Frieda Jørgensen, Heather Aird, Anaïs Painset, Nicolle Som, Oleksii Omelchenko,
et al.
DNA used for short-read
sequencing
was extracted from 800 µl of overnight culture using the automated
Maxwell® RSC 48 instrument
and the Maxwell® RSC
Cultured Cells
DNA (
Promega
) kit following the manufacturer’s instructions; DNA
(58)
In vivo armed macrophages curb liver metastasis through tumor-reactive T-cell rejuvenation
Nat Commun
April 11, 2025
Marco Notaro, Maristella Borghetti, Chiara Bresesti, Giovanna Giacca, Thomas Kerzel, Carl Mirko Mercado, Stefano Beretta, Marco Monti, Ivan Merelli, Silvia Iaia,
et al.
determination Genomic DNA was extracted from
cell culture
samples using the
Maxwell RSC 48 Instrument
(
Promega
/
AS8500
) with
Maxwell RSC Cultured Cells DNA Kit
(
Promega
/
AS1620
). Genomic DNA from whole tissue samples was
(59)
Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models
Elife
April 3, 2025
Ulrike Pech, Jasper Janssens, Nils Schoovaerts, Sabine Kuenen, Carles Calatayud Aristoy, Sandra F Gallego, Samira Makhzami, Gert J Hulselmans, Suresh Poovathingal, Kristofer Davie,
et al.
England Biolabs, Inc (NEB)",
NEB
#
E2621
, "Commercial
assay
, kit",
Maxwell RSC instrument
and kit,
Promega
,"
AS8500
,
AS1340
", "Commercial
assay
, kit",Chromium Single Cell 3′ Library & Gel Bead Kit v2,
10x Genomics
,PN-
120237
, "Commercial
(60)
Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models
Elife
April 3, 2025
Ulrike Pech, Jasper Janssens, Nils Schoovaerts, Sabine Kuenen, Carles Calatayud Calatayud Aristoy, Sandra F Gallego, Samira Makhzami, Gert J Hulselmans, Suresh Poovathingal, Kristofer Davie,
et al.
England Biolabs, Inc (NEB)",
NEB
#
E2621
, "Commercial
assay
, kit",
Maxwell RSC instrument
and kit,
Promega
,"
AS8500
,
AS1340
", "Commercial
assay
, kit",Chromium Single Cell 3′ Library & Gel Bead Kit v2,
10x Genomics
,PN-
120237
, "Commercial
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Maxwell® RSC 48 Instrument from Promega
Supplier Page
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