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Maxwell® RSC 48 Instrument
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Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument from Promega
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Citations:
(175)
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Maxwell® RSC 48 Instrument
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Description
The Maxwell RSC 48 Instrument is a platform for automated purification of nucleic acid from a range of sample types. Purification methods use sample lysis and binding to paramagnetic particles as the primary separation principle.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell® RSC 48 Instrument
Company
Promega
Price
Supplier Page
Catalog Number
AS8500
Quantity
EA
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (175)
(41)
Bioluminescence-based assays for quantifying endogenous protein interactions in live cells
Journal of Biological Chemistry
August 1, 2025
Andrew L. Niles, Michael R.C. Dibble, Thomas Machleidt, Kelli Martino, Matthew R. Swiatnicki, Elizabeth H. Vu, Marie K. Schwinn
clones
was isolated from 5 × 104 to 5 × 105 cells using the Maxwell RSC Culture Cells DNA Kit and the
Maxwell RSC 48 Instrument
(
Promega
) according to the manufacturer’s protocol. DNA was quantitated on the
NanoDrop 8000 Spectrophotometer
(42)
Oregano-based feed additive reduces Salmonella enterica serovar Enteritidis colonization in young broilers
Poultry Science
August 1, 2025
Christina L. Swaggerty, M. Dolores Cabrera, Santiago Sasia, Gabriel Cabrera, Kenneth J. Genovese, J. Allen Byrd, Michael H. Kogut, Rafael A. Cabrera
then loaded into the Maxwell cartridge for RNA isolation. All RNA extractions were carried out on the
Maxwell® RSC 48 instrument
(
Promega
Corp.). Upon completion, the purified RNA samples were stored at −80°C. Quantitative
real-time RT-PCR
(43)
Evaluation of the Global White Lupin Collection Reveals Significant Associations Between Homologous FLOWERING LOCUS T Indels and Flowering Time, Providing Validated Markers for Tracking Spring Ecotypes Within a Large Gene Pool
Int J Mol Sci
July 17, 2025
Wojciech Bielski, Anna Surma, Michał Książkiewicz, Sandra Rychel-Bielska
Qiagen, Hilden, Germany) using
TissueLyser II
(
Qiagen
) at 30 rpm for 30 s. The automated isolation system
Maxwell® RSC 48 Instrument
(
Promega
, Mannheim, Germany) and the
Maxwell® RSC PureFood GMO and Authentication Kit
(
Promega
) [103]
(44)
KDM6A expression loss is frequent in low grade non-invasive urothelial carcinomas of the urinary bladder
Pathologica
June 30, 2025
Florian Viehweger, Natalia Gorbokon, Seyma Büyücek, Henning Plage, Sebastian Hofbauer, Kira Furlano, Sarah Weinberger, Bernhard Ralla, Annika Fendler, Nadine Biernath,
et al.
FFPE specimens using the
Maxwell® RSC DNA FFPE Kit
(
Promega Corporation
, Madison, WI, USA) and the
Maxwell RSC 48 Instrument
according to the manufacturer’s instructions. Targeted gene
sequencing
was performed on a MiniSeq (Illumina,
(45)
KDM6A expression loss is frequent in low grade non-invasive urothelial carcinomas of the urinary bladder
Pathologica
June 30, 2025
Florian Viehweger, Natalia Gorbokon, Seyma Büyücek, Henning Plage, Sebastian Hofbauer, Kira Furlano, Sarah Weinberger, Bernhard Ralla, Annika Fendler, Nadine Biernath,
et al.
FFPE specimens using the
Maxwell® RSC DNA FFPE Kit
(
Promega Corporation
, Madison, WI, USA) and the
Maxwell RSC 48 Instrument
according to the manufacturer’s instructions. Targeted gene
sequencing
was performed on a MiniSeq (Illumina,
(46)
Serum RNA Profile Reflects Fluid Status and Atrophic Retinal Changes in Neovascular Age-Related Macular Degeneration
Int J Mol Sci
May 19, 2025
Hanna Heloterä, Joanna Kostanek, Mikko Liukkonen, Leea Siintamo, Suvi Linna-Kuosmanen, Cezary Watala, Janusz Blasiak, Kai Kaarniranta
Life Science (HiLIFE) and Biocenter Finland. Total RNA was extracted (serum volume 1 mL) using the
Maxwell® RSC 48 Instrument
(Madison, WI, USA) and
Maxwell RSC miRNA Plasma and Serum Kit
(
Promega
, Madison, WI, USA) following
(47)
Pathological Characterization of African Swine Fever Viruses With Genetic Deletions Detected in South Korea
Transbound Emerg Dis
May 6, 2025
Seong-Keun Hong, Ki-Hyun Cho, Jung-Hoon Kwon, Da-Won Kim, Jongho Kim, Da-Young Kim, Hae-Eun Kang, Jong-Soo Lee, Yeon-Hee Kim
Extraction and
Real-Time PCR
Analysis Automatic DNA extraction was carried out in accordance with the
Maxwell RSC 48 instrument
using Maxwell RSC whole blood DNA and
Maxwell RSC viral total nucleic acid purification kit
(
Promega
,
(48)
Molecular dissection of the genetic architecture of phenology underlying Lupinus hispanicus early flowering and adaptation to winter- or spring sowing
Sci Rep
May 2, 2025
Wojciech Bielski, Anna Surma, Jolanta Belter, Bartosz Kozak, Michał Książkiewicz, Sandra Rychel-Bielska
homogenizer (
Qiagen
, Hilden, Germany) for 45 s at 30 rpm. DNA isolation was performed in automated station
Maxwell® RSC 48 Instrument
(
Promega
, Mannheim, Germany) using
Maxwell® RSC PureFood GMO and Authentication Kit
(
Promega
) according
(49)
Population structure and gene flux of Listeria monocytogenes ST121 reveal prophages as a candidate driver of adaptation and persistence in food production environments
Microb Genom
April 17, 2025
Ana Victoria Gutiérrez, Michaela Matthews, Maria Diaz, Thanh Le Viet, Leonardo de Oliveira Martins, Frieda Jørgensen, Heather Aird, Anaïs Painset, Nicolle Som, Oleksii Omelchenko,
et al.
DNA used for short-read
sequencing
was extracted from 800 µl of overnight culture using the automated
Maxwell® RSC 48 instrument
and the Maxwell® RSC
Cultured Cells
DNA (
Promega
) kit following the manufacturer’s instructions; DNA
(50)
In vivo armed macrophages curb liver metastasis through tumor-reactive T-cell rejuvenation
Nat Commun
April 11, 2025
Marco Notaro, Maristella Borghetti, Chiara Bresesti, Giovanna Giacca, Thomas Kerzel, Carl Mirko Mercado, Stefano Beretta, Marco Monti, Ivan Merelli, Silvia Iaia,
et al.
determination Genomic DNA was extracted from
cell culture
samples using the
Maxwell RSC 48 Instrument
(
Promega
/
AS8500
) with
Maxwell RSC Cultured Cells DNA Kit
(
Promega
/
AS1620
). Genomic DNA from whole tissue samples was
(51)
Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models
Elife
April 3, 2025
Ulrike Pech, Jasper Janssens, Nils Schoovaerts, Sabine Kuenen, Carles Calatayud Calatayud Aristoy, Sandra F Gallego, Samira Makhzami, Gert J Hulselmans, Suresh Poovathingal, Kristofer Davie,
et al.
England Biolabs, Inc (NEB)",
NEB
#
E2621
, "Commercial
assay
, kit",
Maxwell RSC instrument
and kit,
Promega
,"
AS8500
,
AS1340
", "Commercial
assay
, kit",Chromium Single Cell 3′ Library & Gel Bead Kit v2,
10x Genomics
,PN-
120237
, "Commercial
(52)
Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models
Elife
April 3, 2025
Ulrike Pech, Jasper Janssens, Nils Schoovaerts, Sabine Kuenen, Carles Calatayud Aristoy, Sandra F Gallego, Samira Makhzami, Gert J Hulselmans, Suresh Poovathingal, Kristofer Davie,
et al.
England Biolabs, Inc (NEB)",
NEB
#
E2621
, "Commercial
assay
, kit",
Maxwell RSC instrument
and kit,
Promega
,"
AS8500
,
AS1340
", "Commercial
assay
, kit",Chromium Single Cell 3′ Library & Gel Bead Kit v2,
10x Genomics
,PN-
120237
, "Commercial
(53)
Mutant KRAS and GATA6 Stratify Survival in Patients Treated with Chemotherapy for Pancreatic Adenocarcinoma: A Prospective Cohort Study
Cancers (Basel)
March 5, 2025
Jung Won Chun, Dong-Eun Lee, Nayoung Han, SooBeen Heo, Hyeji Kim, Mi Rim Lee, Hyeong Min Park, Sung-Sik Han, Sang-Jae Park, Tae Hyun Kim,
et al.
were performed from FFPE samples using a
Maxwell RSC RNA FFPE kit
(
Promega
, Madison, WI, USA) on a
Maxwell RSC 48 Instrument
(
Promega
), according to the manufacturer’s protocol. The RNA was eluted in 40 µL of nuclease-free water.
(54)
Intronic SYNE1 Gene Novel Variant Associated with Myocardial Infarction in Young People with a Family History of Premature Atherosclerosis: A Case–Control Study in the Polish Population †
Int J Mol Sci
March 3, 2025
Michał Ambroziak, Jakub Franke, Anna Wójcicka, Monika Kolanowska, Tomasz Jaxa-Chamiec, Andrzej Budaj
Genotyping
Total DNA was extracted from whole peripheral blood samples. The extraction was performed on a
Maxwell® RSC 48 Instrument
(
Promega
, Madison, WI, USA) using the
Maxwell® RSC Blood DNA Kit
, according to the protocol. The targeted
(55)
Machine learning-optimized targeted detection of alternative splicing
Nucleic Acids Research
January 24, 2025
Kevin Yang, Nathaniel Islas, San Jewell, Di Wu, Anupama Jha, Caleb M Radens, Jeffrey A Pleiss, Kristen W Lynch, Yoseph Barash, Peter S Choi
independent days. RNA isolation and processing Total RNA was purified from cell pellets with the
Maxwell RSC 48 instrument
using the
Maxwell RSC simplyRNA Cells Kit
(#
AS1340
,
Promega
). Poly-A selection was subsequently performed
(56)
Development and validation of PCR marker array for molecular selection towards spring, vernalization-independent and winter, vernalization-responsive ecotypes of white lupin (Lupinus albus L.)
Sci Rep
January 21, 2025
Anna Surma, Michał Książkiewicz, Wojciech Bielski, Bartosz Kozak, Renata Galek, Sandra Rychel-Bielska
Maxwell® RSC PureFood GMO and Authentication Kit
(
Promega
, Mannheim, Germany)131 and automated isolation station
Maxwell® RSC 48 Instrument
(
Promega
). No changes to the standard protocol were made. DNA concentration and quality were estimated
(57)
FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models
Commun Med (Lond)
January 18, 2025
Timothy Weeden, Tyler Picariello, Brendan Quinn, Sean Spring, Pei-Yi Shen, Qifeng Qiu, Benjamin F. Vieira, Lydia Schlaefke, Ryan J. Russo, Ya-An Chang,
et al.
controls were subjected to total RNA extraction with the
Maxwell RSC simplyRNA Tissue Kit
using the
Maxwell RSC 48 instrument
(
Promega
) in accordance with the manufacturer’s protocol. Purified total RNA was reverse-transcribed
(58)
Unraveling Effects of miRNAs Associated with APR Leaf Rust Resistance Genes in Hybrid Forms of Common Wheat (Triticum aestivum L.)
Int J Mol Sci
January 14, 2025
Julia Spychała, Aleksandra Noweiska, Agnieszka Tomkowiak, Roksana Bobrowska, Katarzyna Szewczyk, Michał Tomasz Kwiatek
using the Maxwell RSC Plant RNA Isolation Kit (Promega, Madison, WI, USA) harnessing automated station
Maxwell® RSC 48 Instrument
(
Promega
). During RNA isolation, samples were treated with DNAase according to the manufacturer’s recommendations.
(59)
Oral administration of Lactobacillus casei DG® after ileostomy closure in restorative proctocolectomy: a randomized placebo-controlled trial (microbiota and immune microenvironment in pouchitis -MEP1)
Gut Microbes
December 31, 2024
Imerio Angriman, Melania Scarpa, Edoardo Savarino, Ilaria Patuzzi, Alessandra Rigo, Andromachi Kotsafti, Astghik Stepanyan, Elisa Sciuto, Francesco Celotto, Silvia Negro,
et al.
Maxwell® RSC Fecal Microbiome DNA Kit
following the manufacturer’s instructions (
Promega
, Madison, Wisconsin) on a
Maxwell® RSC 48 Instrument
(
Promega
). The
sequencing
protocol was performed at BMR Genomics Srl. Briefly: V3–V4 regions of 16S
(60)
Performance evaluation of nine reference centers and comparison of DNA extraction protocols for effective surveillance of Leishmania-infected Phlebotomine sand flies: Basis for technical recommendations
PLOS Neglected Tropical Diseases
December 23, 2024
Jorian Prudhomme, Aymeric Delabarre, Bulent Alten, Umut Berberoglu, Eduardo Berriatua, Gioia Bongiorno, José Manuel Cristovao, Maya Davidovich-Cohen, Trentina Di Muccio, Ozge Erisoz Kasap,
et al.
RSC Viral TNA (Promega, Southampton, England) and RSC Blood DNA (Promega, Southampton, England) using
Maxwell RSC 48 instrument
(
Promega
). Amplifications were realized using a QuantStudio 5
Real-Time PCR System
(Applied Biosystems,
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Maxwell® RSC 48 Instrument from Promega
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