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Maxwell® RSC 48 Instrument
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Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument
Maxwell® RSC 48 Instrument from Promega
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Citations:
(183)
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Maxwell® RSC 48 Instrument
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Description
The Maxwell RSC 48 Instrument is a platform for automated purification of nucleic acid from a range of sample types. Purification methods use sample lysis and binding to paramagnetic particles as the primary separation principle.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell® RSC 48 Instrument
Company
Promega
Price
Supplier Page
Catalog Number
AS8500
Quantity
EA
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (183)
(21)
Adapting Clinical Chemistry Plasma as a Source for Liquid Biopsies
medRxiv
February 27, 2026
Spencer C. Ding, Jingru Yu, Tiepeng Liao, Lauren S. Ahmann, Yvette Y. Yao, Chandler Ho, Linlin Wang, Benjamin A. Pinsky, Wei Gu
described(26). DNA extraction Cell-free DNA (cfDNA) was extracted from 0.5 to 1 mL of plasma using the
Maxwell RSC 48 instrument
(
Promega
) with the
Maxwell RSC ccfDNA Plasma Kit
(
AS1480
), following the manufacturer’s instructions.
(22)
Immunopeptidomics of cutaneous leishmaniasis patients reveals the natural antigenic landscape
Frontiers in Immunology
February 20, 2026
Nicky de Vrij, Elise Pepermans, Louise Laurijssen, Thao-Thy Pham, Lauren Thijs, Kurt Boonen, Kadrie Ramadan, Ilse Maes, Yetemwork Aleka, Mekibib Kassa,
et al.
the
mass spectrometry
-based immunopeptidomics
assay
(Cohort 1 study samples) (Figure 1), using the
Maxwell® RSC 48 instrument
(
Promega
, Wisconsin, U.S.A.) with the
Maxwell® RSC Whole Blood DNA kit
(
Promega
, Wisconsin, U.S.A.)
(23)
Pitfalls in body fluid identification – age independent DNA methylation markers for vaginal secretions and menstrual blood in sexual assaults
International Journal of Legal Medicine
February 19, 2026
Helen Konrad, Leandra Jürgens, Paula Hiekel, Sophie Fertyk, Daniela Wübbe, Benno Hartung, Micaela Poetsch
site. DNA extraction was performed using the DNA IQ Casework Pro Kit and
Casework Extraction Kit
in the
Maxwell® RSC 48 instrument
(
Promega
, Walldorf, Germany). Subsequently, DNA was quantified using the
PowerQuant™ System
(
Promega
)
(24)
Development of a non-invasive diagnostic method for pathogenic RNA viruses using sebum wiped from the cat’s body surface
Scientific Reports
February 18, 2026
Yuri V Fukushima, Namiko Saito, Hirohisa Mekata, Akatsuki Saito
RNA from cat BSLs was processed using the
Maxwell® RSC 48 Instrument
(
Promega
, Madison, WI, USA; Cat#
AS8500
) in combination with the
Maxwell® RSC miRNA Plasma and Serum Kit
(
Promega
; Cat#
AS1680
), according to
(25)
Analysis of gut microbiota in super donors for fecal microbiota transplantation and isolated gut commensal bacteria of inhibition against Clostridioides difficile
Intestinal Research
February 4, 2026
Ki Sung Kang, Gee Hyeun Choi, Yu Jin Kim, Won Suk Lee, Do Eun Lee, Min Yeong Kim, Hyuk Yoon, Dong Ho Lee
RSC PureFood Pathogen Cartridge. Prior to this, the cartridges were placed onto the Deck Tray of the
Maxwell RSC 48 Instrument
(
Promega
). Following the transfer of the supernatant, 300 μL of
Lysis Buffer
and 30 μL of RNase were
(26)
Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect
J Exp Med
February 2, 2026
Kyle Rhodehouse, Carolin Zitzmann, Meghana Ravi, Ciara Armstrong, Milica Moskovljevic, Hannah P. Moore, Courtney Schill, Emily J. Fray, Mithra R. Kumar, Toni Penney,
et al.
(Del Prete et al., 2016). Animal genotyping Genomic DNA was isolated from whole blood samples with a
Maxwell RSC 48 instrument
using a
Maxwell RSC Buffy Coat DNA kit
according to the manufacturer’s protocol (
Promega
). Amplicons
(27)
The COMFORTage project: study protocol for the integration of multiple sources towards personalised preventions at Ace Alzheimer Center Barcelona
Frontiers in Digital Health
January 26, 2026
Sergi Valero, Andrea Miguel, Josep Blazquez-Folch, Berta Calm, Montserrat Alegret, Ariadna Solivar, George Manias, Athos Antoniades, Nelina Angelova, Despina Psimaris,
et al.
research purposes (42). 2.4.6
Genotyping
Genomic DNA is extracted from buffy coat samples using the
Maxwell RSC 48 instrument
(
Promega
) with the
AS1540
DNA extraction kit, ensuring high-quality samples for genetic analysis, and
(28)
Tracking Antimicrobial Resistance in Salmonella via Poultry Supply Chains, Human Clinical Samples, and Environmental Reservoirs
Foods
January 23, 2026
Diana M. Álvarez-Espejo, Diego Fredes-García, Constanza Díaz-Gavidia, Sebastián Gutiérrez, Rocio Barron-Montenegro, Francisca P. Álvarez, Rodrigo Constenla-Albornoz, Vivien Cadet-Arenas, Angélica Reyes-Jara, Jorge Olivares-Pacheco,
et al.
S1A–C). Genomic DNA from poultry meat isolates was extracted using the
Cultured Cells
DNA Kit on a
Maxwell RSC-48 Instrument
(
Promega
, Madison, WI, USA). Libraries were constructed with the Illumina DNA Prep kit (Illumina, San
(29)
The Regulation of Oxidative Stress Is a Conserved Response to RNA Virus Infection in Fish
Antioxidants (Basel)
January 12, 2026
Alejandro Romero, Patricia Pereiro, Antonio Figueras, Beatriz Novoa
extracted using the SimplyRNA Tissue Kit (Promega Biotech Iberica, Madrid, Spain) in the automated
Maxwell RSC 48 Instrument
(
Promega
Biotech Iberica, Madrid, Spain), following the manufacturer’s protocol. RNA concentration was
(30)
Metadata assessment of non-human primate studies of AAV9 uncovers potential tissue specific variation in expression efficiency
Gene Therapy
January 7, 2026
Muhammad Shahrukh, Julianne R. Sweeney, Tony del Rio, Fatih Ozsolak
chloroform. The aqueous phase was collected and processed using the
Maxwell® RSC SimplyRNA tissue kit
and
Maxwell RSC 48 Instrument
(
Promega Corporation
,
AS1340
). Purified RNA samples were treated with Turbo DNase (
Thermo Fisher
,
AM2238
)
(31)
The structure and allelic diversity of the self-incompatibility locus (S-locus) in diploid potatoes inferred from genome sequences and transcriptome data from styles and pollen
Plant Genome
December 22, 2025
Mercedes Ames, Dennis Halterman, Paul C. Bethke
nitrogen. RNA extraction was done using the
Maxwell RSC Plant RNA Kit
(
Promega Corporation
) and the
Maxwell RSC 48 instrument
(
Promega
). Extracted RNA was submitted to the
Gene Expression
Center at the University of Wisconsin‐Madison
(32)
Exploring transmission dynamics in epidemiologically linked pulmonary tuberculosis cases and household contacts: a WGS-based investigation
BMC Genomics
December 18, 2025
Getachew Seid, Andrea Maurizio Cabibbe, Betselot Zerihun, Ayinalem Alemu, Getu Diriba, Gemechu Tadesse, Wilber Sabiiti, Kiarash Moghaddasi, Ilaria Iannucci, Daniela Maria Cirillo,
et al.
extracted and purified using the
Maxwell RSC Pathogen Total Nucleic Acid Kit
(
Promega
)
procedure
on the
Maxwell RSC 48 Instrument
according to the manufacturer’s instructions [20]. DNA libraries were generated using the Illumina DNA
(33)
Campylobacter jejuni stimulates a robust cytokine response in the cecal tonsil following a repeated challenge infection model
Poultry Science
December 1, 2025
Christina L. Swaggerty, Alejandra V. Velilla, Kenneth J. Genovese, J. Allen Byrd, Michael H. Kogut
Scientific). Total RNA was extracted from the homogenate using the
Maxwell® RSC SimplyRNA Tissue Kit
on the
Maxwell® RSC 48 instrument
according to the manufacturer’s instructions (
Promega
Corp., Madison, WI). Briefly, Thioglycerol/Homogenization
(34)
Infection Dynamics and Host Biomarker Identification for Spotty Liver Disease in Chickens
Vet Sci
November 29, 2025
Helen James, Emily Gan, Robert J. Moore, Daniel M. Andrews, Thi Thu Hao Van
Control Approximately 20–30 mg of liver tissue was homogenised, and total RNA was extracted using the
Maxwell® RSC 48 Instrument
with the
Maxwell® RSC miRNA Tissue Kit
(
Promega
, Madison, WI, USA) according to the manufacturer’s instructions.
(35)
Germline Variant Call Accuracy in Whole Genome Sequence Data from Canine Formalin-Fixed Paraffin-Embedded Tissue Samples
Genes (Basel)
November 11, 2025
Vidhya Jagannathan, Tosso Leeb
derived from three 2-month-old male
dogs
(
dogs
#1–3) using the Maxwell RSC Whole Blood Kit and the
Maxwell RSC 48 instrument
(
Promega
, Dübendorf, Switzerland). The size distribution of the DNA fragments was evaluated on a Femto
(36)
The histone variant H3.14 is an early player in the abiotic stress response of Arabidopsis
Developmental Cell
November 3, 2025
Rocío Nunez-Vazquez, Sofía Madeira, Laura Rodríguez-Casillas, Diego Gomez-Martinez, Bénédicte Desvoyes, Crisanto Gutierrez
RNA,
Promega
,https://www.promega.es/en/products/
lab-automation
/automated-dna-rna-extraction-
purification
-maxwell/
maxwell-rsc-48-instrument
/?tabset0=0&cs=y BioruptorPico,Diagenode,https://www.diagenode.com/en/p/bioruptorpico2 AmershamTM Imager
(37)
Whole-genome nanopore sequencing and automatic downstream analysis of respiratory syncytial virus using RSVTyper
Scientific Reports
October 31, 2025
Duyen Bao Le, Inga Tometten, Nadine Lübke, Martha Paluschinski, Anna-Kathrin Schupp, Lutz Ehlkes, Pascal Kreuzer, Nicole Zacharias, Jörg Timm, Alexander Dilthey,
et al.
cell culture
supernatant or nasopharyngeal swabs and eluted in 60 µL, using the
Maxwell RSC Blood DNA Kit
on
Maxwell® RSC 48 Instrument
(
Promega
) following the manufacturer’s instructions. Total nucleic acids from wastewater samples were
(38)
Whole-Genome Sequencing of Hepatitis B Virus Genotypes E and A in Zambia Reveals Limited Viral Diversity in HIV Coinfection
Open Forum Infectious Diseases
October 30, 2025
Michael J Vinikoor, Andreas Walker, Bright Nsokolo, Taonga Musonda, Guy Muula, Eleftherios Michailidis, Gilles Wandeler, Nadia Alatrakchi, Paul Kelly, Maximillian Damagnez,
et al.
from 300μL of serum or plasma was extracted automatically using the
Maxwell RSC Blood DNA Kit
on a
Maxwell RSC 48 Instrument
(both
Promega
), and the complete HBV genome was amplified in 2 fragments as previously described [20].
(39)
Chromosome-level genome assembly of the hamour (orange-spotted grouper), Epinephelus coioides
F1000Research
October 29, 2025
Razan Khalifa, Tim Bean, Dana Albatesh, Ronny van Aerle, Zenaba Kahtir, Zainab Hizam, Marta Gut, Francisco Câmara, Fernando Cruz, Jèssica Gómez-Garrido,
et al.
(
Agilent
). DNA was stored at +4 °C until library preparation. Total RNA was extracted using a
Promega
Maxwell ® RSC 48 Instrument
and Maxwell RSC simply RNA Tissue kit (Promega), quantified using an
Invitrogen
Qubit RNA BR Assay kit
(40)
Detection of the intergenic region III and multigene family 505 9R and 10R-V variant of African swine fever virus genotype II on pig farms in South Korea
Arch Virol
October 26, 2025
Ki-Hyun Cho, Da-Young Kim, Seong-Keun Hong, Dae-Sung Yoo, Hae-Eun Kang, Yeon-Hee Kim
in sterile phosphate-buffered saline in a ratio of
1:10
w/v and centrifuged at 6000 g for 5 min. A
Maxwell RSC 48 instrument
(
Promega
, Madison, WI, USA) was used to extract viral nucleic acids from blood and tissue samples according
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Maxwell® RSC 48 Instrument from Promega
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