The Biocompare Nucleic Acid Purification Search Tool is a searchable catalog of products dedicated to the isolation or extraction of DNA and RNA. Listed by leading life science companies, these kits and reagents enable optimized and efficient purifications of nucleic acid materials necessary for downstream molecular biology applications. These products can help streamline workflows in cloning, PCR, RT-PCR, sequencing, library construction, genotyping, and microbial analysis. Use our database to help simplify product search by entering keywords and selecting filters for citations, reviews, nucleic acid type, source/sample type, purification scale, format, and supplier company.
The spin column method of isolating DNA or RNA is widely used in many nucleic acid purification kits. A type of solid-phase extraction, the principle relies on nucleic acid binding to a solid surface, such as silica gel. Once the cellular lysate is eluted, addition of buffers with varying conditions, such as in pH or salt concentration, facilitate nucleic acid binding and removal of unwanted particles. Spin-based kits that utilize 96-well plates for centrifugation are also available for DNA extraction workflows that require higher throughputs.