Anti-TNFRSF1A antibodies are used in the immunodetection of the protein TNF receptor superfamily member 1A. In humans, the canonical protein has a reported length of 455 amino acid residues and a mass of 50.5 kDa. Its subcellular localization is in the Golgi, cell membrane, and is secreted. Up to 5 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. TNFRSF1A is a known receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. Post-translational modifications have been described, including glycosylation and protein cleavage. TNFRSF1A is also used as a cellular marker for characterizing granulocytes. Synonyms for this target antigen include FPF, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, and CD120a. TNFRSF1A gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. Over 560 citations in the literature describe the use of TNFRSF1A antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Flow Cytometry are also common applications.