Anti-Perforin antibodies are essential reagents in flow cytometry for detecting the target protein, perforin 1 (PRF1). Perforin is a pore-forming protein that allows the release of granzymes and subsequent cytolysis of target cells, enabling cell death and defense against virus-infected or neoplastic cells. The protein is localized to the cell membrane, cytolytic granules, and is secreted. Examine the supplier's provided validation data when comparing Perforin antibodies for flow cytometry. Also look for application-specific recommendations, such as dilutions, protocols, sample types, and other helpful usage notes.