Anti-PTPN1 antibodies are used in the immunodetection of the protein protein tyrosine phosphatase non-receptor type 1. In humans, the canonical protein has a reported length of 435 amino acid residues and a mass of 50 kDa. Its subcellular localization is in the ER and cell membrane. It is reported to be expressed in keratinocytes. A member of the Protein-tyrosine phosphatase protein family, PTPN1 is reported to be a tyrosine-protein phosphatase, which acts as a regulator of endoplasmic reticulum unfolded protein response. Synonyms for this target antigen include tyrosine-protein phosphatase non-receptor type 1, protein tyrosine phosphatase, placental, protein-tyrosine phosphatase 1B, and PTP1B. PTPN1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 100 citations in the literature describe the use of PTPN1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.