Fig 1: Evaluation of inflammatory responses. Representative images for the detection of astrocytes a–c, and microglia d–f, co-stained with Hoechst for the detection of cellular nucleus (blue). Scale bar: 200 µm. Graphic representation of fluorescence intensity quantification for GFAP g and IBA1 h. In both cases, statistical analysis was performed through one-way ANOVA (n = 5) and Tukey’s post hoc test, * p < 0.05. ** p < 0.01 and *** p < 0.001. i. protein levels for TLR4 and PTP1B where two representative samples out of four or five per group are shown (n = 4–5). All results were represented as mean ± SD. Groups were compared against each other using one-way ANOVA and Tukey post-test, * p < 0.05 and ** p < 0.01