PTP1B Antibody AF1366 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemPTP1B Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $419.00Supplier Page View Company Product Page
Catalog NumberAF1366
ApplicationsImmunohistochemistry,Immunoprecipitation,Western Blot,Simple Western,Immunocytochemistry
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse
TargetPTP1B
Conjugate/TagUnconjugated
HostRabbit
Quantity100 ug (also 25 ug)
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human PTP1B
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameprotein tyrosine phosphatase non-receptor type 1
NCBI Gene AliasesPTP1B

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects endogenous human PTP1B in Western blots.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175FASEB journal : official publication of the Federation of American Societies for Experimental BiologySeptember 1, 2019Kim DY, Park JA, Kim Y, Noh M, Park S, Lie E, Kim E, Kim YM, Kwon YG.MilliporeSigma), VE–protein tyrosine phosphatase (PTP) (PAB048Hu01; Cloud-Clone, Katy, Houston, USA), PTP1B (AF1366; R&D Systems), and IgG (26702; GeneTex, Irvine, CA, USA) were used for immunoprecipitation. SALM4 (PA5-20706)

(2) The pseudophosphatase phogrin enables glucose-stimulated insulin signaling in pancreatic β cellsThe Journal of biological chemistryApril 20, 2018Torii S, Kubota C, Saito N, Kawano A, Hou N, Kobayashi M, Torii R, Hosaka M, Kitamura T, Takeuchi T, et al.

(3) A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermiseLifeOctober 18, 2017Mishra A, Oulès B, Pisco AO, Ly T, Liakath-Ali K, Walko G, Viswanathan P, Tihy M, Nijjher J, Dunn SJ, et al.

(4) Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cellsCell death & diseaseMay 11, 2017Hilmarsdottir B, Briem E, Halldorsson S, Kricker J, Ingthorsson S, Gustafsdottir S, Mælandsmo GM, Magnusson MK, Gudjonsson T.combinations: PTP1B mouse (BD, #610139) with Src rabbit (Cell Signaling, #2109) and PTP1B rabbit (R&D Systems, AF1366) with EGFR mouse (BD, #555996) overnight, followed by a standard PLA protocol according to the manufacturer's

(5) Selective activation of SHP2 activity by cisplatin revealed by a novel chemical probe-based assayBiochemical and biophysical research communicationsJanuary 1, 2010Kuo CC, Chu CY, Lin JJ, Lo LC.

(6) Cysteine S-nitrosylation protects protein-tyrosine phosphatase 1B against oxidation-induced permanent inactivationThe Journal of biological chemistryDecember 12, 2008Chen YY, Chu HM, Pan KT, Teng CH, Wang DL, Wang AH, Khoo KH, Meng TC.

(7) Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug responseOncogeneAugust 21, 2008Lei K, Townsend DM, Tew KD.was immunoprecipitated using polyclonal rabbit anti-PTP1B antibody (R&D Systems, Minneapolis, MN, USA, AF1366) and PTP1B phosphatase activity was measured as the amount of released phosphate from phosphopeptide

(8) Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasionThe Journal of cell biologyMarch 10, 2008Cortesio CL, Chan KT, Perrin BJ, Burton NO, Zhang S, Zhang ZY, Huttenlocher A.

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PTP1B Antibody

PTP1B Antibody

PTP1B Antibody

PTP1B Antibody

PTP1B Antibody

PTP1B Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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PTP1B Antibody from R&D Systems, a Bio-Techne Brand

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