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Automated DNA/RNA Purification Sample Preparation Workstations
Maxwell RSC Instrument
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Maxwell RSC Instrument
Maxwell RSC Instrument
Maxwell RSC Instrument from Promega
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Citations:
(849)
Figures:
(1)
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Maxwell RSC Instrument
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Description
The Maxwell RSC Instrument is a platform for automated extraction of nucleic acid from a range of sample types. Extraction methods use sample lysis and binding to paramagnetic particles followed by washing steps and elution.
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Maxwell RSC Instrument
Company
Promega
Price
Supplier Page
View Company Product Page
Catalog Number
AS4500
Quantity
EA
Processing Time
30 to 60 min (depending on sample type and method)
Capacity
Up to 16
Dimensions
(WxDxH) 330.2 x 345.2 x 299.7 mm (13 x 13.6 x 11.8 in)
UV Lamp
Avg. lifetime approximately 6,000 hrs
Molecular Weight
~85kDa
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Promega
2800 Woods Hollow Rd
Madison
,
WI
53711
United States
Phone
: Tel: +1 (608) 274-4330
Fax: +1 (608) 277-2516
Email: custserv@promega.com
techserv@promega.com
Company Profile
Website:
http://www.promega.com
Citations (849)
(581)
Independent DSG4 frameshift variants in cats with hair shaft dystrophy
Molecular Genetics and Genomics
January 1, 2022
Sarah Kiener, Ana Rostaher, Silvia Rüfenacht, Vidhya Jagannathan, John P. Sundberg, Monika Welle, Tosso Leeb
S1). Genomic DNA was isolated from ETDA blood samples with the Maxwell RSC Whole Blood Kit using a
Maxwell RSC instrument
(
Promega
, Dübendorf, Switzerland). Histopathological examinations Skin
biopsies
from alopecic skin
(582)
PIEZO1 mechanoreceptor activation reduces adipogenesis in perivascular adipose tissue preadipocytes
Frontiers in endocrinology
January 1, 2022
Rendon CJ, Flood E, Thompson JM, Chirivi M, Watts SW, Contreras GA.
well #4 of the Maxwell® RSC Cartridge to eliminate genomic DNA. The RNA was automated extracted in
Maxwell® RSC Instrument
(
Promega
, Madison, WI, USA) following the manufacturer protocol. The purity, concentration, and integrity
(583)
Long term high glucose exposure induces premature senescence in retinal endothelial cells
Frontiers in physiology
January 1, 2022
Bertelli PM, Pedrini E, Hughes D, McDonnell S, Pathak V, Peixoto E, Guduric-Fuchs J, Stitt AW, Medina RJ.
control HRMECs. Extraction was performed using the
Maxwell RSC simplyRNA Cells Kit
(Promega) and a
Maxwell RSC instrument
(
Promega
) following the manufacturer’s instructions. Three biological replicates were sent for each
(584)
Clinical relevance and prognostic role of preoperative cell-free single-stranded DNA concentrations in colorectal cancer patients
Korean Journal of Clinical Oncology
December 31, 2021
Hyun Soo Song, Dong Hyun Kang, Hyunjung Kim, Tae Sung Ahn, Tae Wan Kim, Moo-Jun Baek
analysis. Isolation of ccfDNA from plasma ccfDNA was isolated from plasma (100 μL) using a
Maxwell RSC Instrument
(
AS4500
;
Promega
, Madison, WI, USA) and a
Maxwell RSC ccfDNA Plasma Kit
(
AS1480
,
Promega
) according to the user
(585)
Distribution and Genetic Diversity of Hepatitis E Virus in Wild and Domestic Rabbits in Australia
Pathogens
December 17, 2021
Maria Jenckel, Ina Smith, Tegan King, Peter West, Patrick L. Taggart, Tanja Strive, Robyn N. Hall
stabilization solution [26,27]. RNA from tissue samples (liver and
bone
marrow) was extracted using the
Maxwell® RSC instrument
(
Promega
) in combination with the
Maxwell® RSC SimplyRNA Tissue Kit
(
Promega
) according to the manufacturer’s
(586)
Clinicopathological and Molecular Characteristics of Macroscopically Yellowish-Colored Chromophobe Renal Cell Carcinoma Compared to Non-Yellowish-Colored Chromophobe Renal Cell Carcinoma
Clin Pathol
December 12, 2021
Fumiyoshi Kojima, Ibu Matsuzaki, Naoto Kuroda, Yurina Mikasa, Fidele Y Musangile, Ryuta Iwamoto, Yuichi Takahashi, Akiko Matsubara, Yasuo Kohjimoto, Isao Hara,
et al.
was extracted from
formalin-fixed paraffin-embedded
ChRCC or non-neoplastic renal tissue using the
Maxwell® RSC Instrument
(
Promega Corporation
, Madison, WI, USA) with the
Maxwell RSC RNA FFPE Kit
(
Promega Corporation
, Madison,
(587)
Clinicopathological and Molecular Characteristics of Macroscopically Yellowish-Colored Chromophobe Renal Cell Carcinoma Compared to Non-Yellowish-Colored Chromophobe Renal Cell Carcinoma
Clinical Pathology
December 12, 2021
Fumiyoshi Kojima et al.
was extracted from
formalin-fixed paraffin-embedded
ChRCC or non-neoplastic renal tissue using the
Maxwell® RSC Instrument
(
Promega Corporation
, Madison, WI, USA) with the
Maxwell RSC RNA FFPE Kit
(
Promega Corporation
, Madison,
(588)
Alteration of DNA mismatch repair capacity underlying the co-occurrence of non-small-cell lung cancer and nonmedullary thyroid cancer
Scientific Reports
December 1, 2021
Shiro Fujita, Katsuhiro Masago
analysis MSI analyses were performed on genomic DNA extracted using the Maxwell RSC FFPE DNA Kit and
Maxwell RSC Instrument
(
Promega
). MSI analyses were performed using the MSI Analysis System v1.2 (Promega). The analysis included
(589)
Genome-wide DNA methylation profiling is able to identify prefibrotic PMF cases at risk for progression to myelofibrosis
Clinical Epigenetics
December 1, 2021
Ulrich Lehmann, Helge Stark, Stephan Bartels, Jerome Schlue, Guntram Büsche, Hans Kreipe
committee for retrospective analyses. DNA extraction Extraction of genomic DNA was performed using the
Maxwell RSC instrument
(
Promega
, Madison, WI, USA) and the
Maxwell RSC DNA FFPE kit
according to the manufacturer's instructions.
(590)
DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status
Clinical Epigenetics
December 1, 2021
Philipp Jurmeister, Karsten Weber, Sonia Villegas, Thomas Karn, Michael Untch, Anne Thieme, Volkmar Müller, Eliane Taube, Peter Fasching, Wolfgang D. Schmitt,
et al.
performed to reach a
tumor
cell content of at least 70%. Semi-automated DNA extraction was performed on the
Maxwell RSC Instrument
using the Maxwell RSC FFPE Plus DNA Purification Kit (Custom, AX4920;
Promega
), according to the manufacturer’s
(591)
Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer
Nature Communications
December 1, 2021
Gillian Vandekerkhove, Jean-Michel Lavoie, Matti Annala, Andrew J. Murtha, Nora Sundahl, Simon Walz, Takeshi Sano, Sinja Taavitsainen, Elie Ritch, Ladan Fazli,
et al.
using the QIAGEN DNeasy Blood and Tissue Kit, or the
Promega
Maxwell® RSC Blood DNA Kit
and
Promega
Maxwell® RSC Instrument
. Extracted gDNA was quantified with a NanoDrop spectrophotometer. For archival FFPE tissue samples,
(592)
UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication
Scientific Reports
December 1, 2021
Mara Biasin et al.
days post
infection
. RNA was extracted from VeroE6
cell culture
supernatant and cell lysate by the
Maxwell RSC Instrument
with
Maxwell RSC Viral Total Nucleic Acid Purification Kit
(
Promega
, Fitchburg, WI, USA), quantified
(593)
Sensitive and Specific qPCR and Nested RT-PCR Assays for the Detection of Tobacco Streak Virus in Soybean
PhytoFrontiers™
December 1, 2021
Cristina Zambrana-Echevarría, Mitchell G. Roth, Ranjit Dasgupta, Thomas L. German, Carol L. Groves, Damon L. Smith
TRIzol Plus RNA Purification Kit
(
Invitrogen
, Carlsbad, CA, U.S.A.) or the
Maxwell RSC Plant RNA kit
with the automated
Maxwell RSC Instrument
(
Promega
Corp., Madison, WI, U.S.A.) according to the manufacturers’ instructions. RNA quantity was
(594)
Identification of molecular signatures associated with early relapse after complete resection of lung adenocarcinomas
Scientific Reports
December 1, 2021
Helen Pasternack et al.
DNA and mRNA were performed using the Maxwell RSC DNA FFPE resp. Maxwell RSC RNA FFPE Kits and the
Maxwell RSC instrument
(
Promega
, Fitchburg WI, U.S.A.). DNA samples were quantified with Nanodrop (ThermoFisher, Waltham MA, U.S.A.).
(595)
TP53
mutations are associated with primary endocrine resistance in luminal early breast cancer
Cancer Medicine
December 1, 2021
Isabel Grote et al.
µm) were taken. Genomic DNA was extracted from FFPE specimens with the
Maxwell® RSC DNA FFPE Kit
on a
Maxwell® RSC instrument
(
Promega
) according to the manufacturer's recommendations. DNA concentration was quantified using a
(596)
Weaving Mitochondrial DNA and Y-Chromosome Variation in the Panamanian Genetic Canvas
Genes (Basel)
November 29, 2021
Nicola Rambaldi Migliore, Giulia Colombo, Marco Rosario Capodiferro, Lucia Mazzocchi, Ana Maria Chero Osorio, Alessandro Raveane, Maribel Tribaldos, Ugo Alessandro Perego, Tomás Mendizábal, Alejandro GarcÃa Montón,
et al.
either following a standard phenol/chloroform protocol or with automated extraction performed with the
Maxwell® RSC Instrument
from
Promega
Italia srl (Milan, Italy) according to the manufacturer’s protocol. 2.2. Mitochondrial
(597)
Variant profiling of colorectal adenomas from three patients of two families with MSH3-related adenomatous polyposis
PLOS ONE
November 29, 2021
Claudia Perne et al.
isolation of genomic DNA was performed post-deparaffinisation using the Maxwell RSC DNA Kit and the
Maxwell RSC instrument
(
Promega
, Fitchburg WI, U.S.A.). To reduce FFPE-induced
sequencing
artifacts
, an FFPE repair kit was
(598)
LTBP3 Frameshift Variant in British Shorthair Cats with Complex Skeletal Dysplasia
Genes (Basel)
November 29, 2021
Gabriela Rudd Garces, Anna Knebel, Kirsten Hülskötter, Vidhya Jagannathan, Theresa Störk, Marion Hewicker-Trautwein, Tosso Leeb, Holger A. Volk
from 500 μL EDTA blood samples of the cats in the study with the Maxwell RSC Whole Blood Kit, using a
Maxwell RSC instrument
(
Promega
, Dübendorf, Switzerland). 2.6.
Whole Genome Sequencing
of an Affected Kitten An Illumina
(599)
LAMA2 Nonsense Variant in an Italian Greyhound with Congenital Muscular Dystrophy
Genes (Basel)
November 19, 2021
Matthias Christen, Victoria Indzhova, Ling T. Guo, Vidhya Jagannathan, Tosso Leeb, G. Diane Shelton, Josep Brocal
Italian Greyhounds. Genomic DNA was isolated from EDTA blood with the Maxwell RSC Whole Blood Kit using a
Maxwell RSC instrument
(
Promega
, Dübendorf, Switzerland). 2.4.
Whole-Genome Sequencing
An Illumina TruSeq
PCR
-free DNA library
(600)
Geographic Variations in Test Reactivity for the Serological Diagnosis of Trypanosoma cruzi Infection
Journal of Clinical Microbiology
November 18, 2021
Carine Truyens, Eric Dumonteil, Jackeline Alger, Maria Luisa Cafferata, Alvaro Ciganda, Luz Gibbons, Claudia Herrera, Sergio Sosa-Estani, Pierre Buekens
DNA was extracted from 300 μl of blood conserved in 6 M guanidine HCl, 0.2 M EDTA using an automated
Maxwell RSC instrument
(
Promega
Benelux, Leiden, The Netherland) as described previously (13). All DNA extractions and
PCR assays
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Maxwell RSC Instrument from Promega
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