HDAC Assay Kits

HDAC assay kits are available from several suppliers to detect the activity of histone deacetylases (HDACs). HDACs are enzymes that remove the acetyl group from the lysine residues of core histones, which results in a more tightly packed chromatin structure and repression of gene expression. They play important roles in the regulation of the cell cycle and tissue differentiation. Certain HDAC members, such as HDAC1, have also been implicated in regulating non-histone proteins, such as those involved in disease. HDAC assay kits use the deacetylase activity of HDACs against a synthetic acetylated peptide substrate that, upon reaction, will produce a fluorescent signal. Visit the HDAC assay kit suppliers for more details, including kit components.