These Bcl-2 ELISA kits are immunodetection tools for measuring the levels of Bcl-2 in biological samples. Bcl-2 is an alias of the human BCL2 gene, which encodes the protein, BCL2 apoptosis regulator. Notably, Bcl-2 is known to play a role in the apoptotic pathway and neuronal development, among other functions. The BCL2 protein is 239 amino acid residues in length and 26.3 kilodaltons in mass. However, as many as 2 protein isoforms have been identified. It is localized to the nucleus, mitochondria, ER, and cytoplasm of the cell. In terms of tissue specificity, it is reported to be expressed in a variety of tissues. This protein is known to be ubiquitinated, cleaved and phosphorylated. Other names for this target antigen include PPP1R50, apoptosis regulator Bcl-2, and B-cell CLL/lymphoma 2.
The detection range for different Bcl-2 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 100 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.